Salient objects often capture attention in a purely exogenous way, followed by inhibition of their locations after a period. Yet, the neural circuits underlying the exogenous attention remain underspecified. Seidel Malkinson et al. explore this by uncovering large-scale cortical gradients associated with exogenous attention within the human cortex.

Humans coordinate their eye, head, and body movements to gather information from a dynamic environment while maximizing reward and minimizing biomechanical and energetic costs. However, such natural behavior is not possible in traditional experiments employing head/body restraints and artificial, static stimuli. Therefore, it is unclear to what extent mechanisms of fixation selection discovered in lab studies, such as inhibition-of-return (IOR), influence everyday behavior. To address this gap, participants performed nine real-world tasks, including driving, visually searching for an item, and building a Lego set, while wearing a mobile eye tracker (169 recordings; 26.6 h). Surprisingly, in all tasks, participants most often returned to what they just viewed and saccade latencies were shorter preceding return than forward saccades, i.e., consistent with facilitation, rather than inhibition, of return. We hypothesize that conservation of eye and head motor effort (\"laziness\") contributes. Correspondingly, we observed center biases in fixation position and duration relative to the head\'s orientation. A model that generates scanpaths by randomly sampling these distributions reproduced all return phenomena we observed, including distinct 3-fixation sequences for forward versus return saccades. After controlling for orbital eccentricity, one task (building a Lego set) showed evidence for IOR. This, along with small discrepancies between model and data, indicates that the brain balances minimization of motor costs with maximization of rewards (e.g., accomplished by IOR and other mechanisms) and that the optimal balance varies according to task demands. Supporting this account, the orbital range of motion used in each task traded off lawfully with fixation duration.

Attention can be covertly shifted to peripheral stimuli to improve their processing. However, attention is also then inhibited against returning to the previously attended location; thus, both detection and discrimination of a stimulus presented at that location decrease (the inhibition of return [IOR] effect). The after-effect of the covert orienting hypothesis postulates a close link between attention shifting, IOR, and oculomotor control. The fixation offset, which improves the generation of saccades, decreases IOR in detection tasks, suggesting a close link between IOR and oculomotor control. However, according to some alternative views (e.g., the input-based IOR hypothesis and the object files segregation/integration hypothesis), IOR may be related to some sensory rather than motor processes. Some studies support that view and show that IOR may occur differently in detection and discrimination tasks and that oculomotor processes do not affect IOR in tasks where manual responses are required and eye movements are suppressed. Two experiments presented in this article show that removing the fixation point decreases manual IOR in detection and discrimination tasks. The results are discussed in terms of various theoretical approaches.

There is some evidence for attentional biases in individuals with chronic pain (CP). Cultural and linguistic differences might affect the manifestation of these processes across populations. However, such attentional biases have not been explored in the Arabic-speaking population. The current study investigated these attentional biases and possible associations with resilience. Two matched groups of Arabic-speaking participants with (58) and without (58) CP were recruited from Jordan and the United Kingdom. They completed emotionally modified versions of the Posner cueing and Stroop tasks, alongside questionnaires. Significant group differences were found for the Posner task, with the CP group exhibiting disengagement revealed by the inhibition of return (IOR) effect for sensory pain-related cues compared to delayed disengagement for the other cue types. The control group showed IOR across cue types. No group differences were found on the Stroop task. The CP group had lower resilience scores than healthy controls, and resilience moderated performance on the Posner task. The study provides preliminary evidence about the attentional processes in the Arabic population; the speed of disengagement is affected in the CP group with early disengagement for sensory pain-related information compared to affect pain and neutral stimuli. Furthermore, resilience levels in the CP and control group moderated the performance on the Posner task, suggesting that it influences attentional allocation. This study can help in understanding how the phenomenon of attention bias intertwines with the cultural and linguistic factors. Future research should further explore attentional dynamics across different time points in this population and the modulatory effect of resilience.

In the Posner cueing paradigm, the early attentional capture and subsequent inhibition of return (IOR) of attention to the same location, although they are microscale phenomena measured in milliseconds, seem to encapsulate the interaction between two fundamental dimensions of behavior - engaging in and sustaining activity versus withdrawing from and inhibiting activity. In the field of differential psychology, the dynamics of reciprocal relations between these behavioral dimensions have been thought to be determined by central nervous system properties that constitute an individual\'s temperament. Yet the research on any differential effects of temperament on visuospatial orienting is rather sparse and has produced ambiguous results. Here, we used saccadic responses to measure whether individual differences in reactivity as a temperamental trait might affect orienting of visuospatial attention on discrimination cueing tasks. Our results suggested that, in individuals with lower reactivity, attentional capture took place at a short stimulus onset asynchrony (SOA), producing a facilitatory cueing effect, which was not the case in those who were higher in reactivity. We explain and discuss these results with the Regulative Theory of Temperament.

We explore the world by constantly shifting our focus of attention toward salient stimuli and then disengaging from them in search of new ones. The alpha rhythm (8-13 Hz) has been suggested as a pivotal neural substrate of these attentional shifts, due to its local synchronization and desynchronization that suppress irrelevant cortical areas and facilitate relevant areas, a phenomenon called alpha lateralization. Whether alpha lateralization tracks the focus of attention from orienting toward a salient stimulus to disengaging from it is still an open question. We addressed it by leveraging the phenomenon of inhibition of return (IOR), consisting of an initial facilitation in response times (RTs) for stimuli appearing at an exogenously cued location, followed by a suppression of that location. Our behavioral data from human participants showed a typical IOR effect with both early facilitation and subsequent inhibition. In contrast, alpha lateralized in the cued direction after the behavioral facilitation effect and never re-lateralized compatibly with the behavioral inhibition. Furthermore, we analyzed the interaction between alpha lateralization and microsaccades: while alpha was lateralized toward the cued location, microsaccades were mostly oriented away from it. Crucially, the two phenomena showed a significant positive correlation. These results indicate that alpha lateralization reflects primarily the processing of salient stimuli, challenging the view that alpha lateralization is directly involved in exogenous attentional orienting per se. We discuss the relevance of the present findings for an oculomotor account of alpha lateralization as a modulator of cortical excitability in preparation of a saccade.

An increasing number of studies show that attentional shifting is a primary contributor during the process of learning to read. However, it remains unclear what is the relationship between attentional shifting and word-reading ability in adult readers whose reading skills have matured. More fundamentally, how attentional shifting affects individuals\' reading ability remains poorly understood. To address these issues, we grouped adult readers by the level of Chinese character reading and examined the time course of attentional shifting by setting up multiple stimulus-onset asynchronies (SOAs) in the Posner cue-target paradigm. Based on the phonological mediation hypothesis, we also measured multiple abilities involving phonological processing (i.e., rapid automatic naming and phonological awareness). Results showed that compared with adults at the high reading level, adults at the low reading level showed a selective impairment of attentional disengagement. Rapid automatic naming of Chinese characters played a partially mediating role in the association between attentional shifting and word reading. These results provided evidence for the phonological mediation hypothesis, and suggest that attentional shifting affects word reading by influencing phonological processing in adult Chinese readers.

Action control theories assume that upon responding to a stimulus response and stimulus features are integrated into a short episodic memory trace; repeating any component spurs on retrieval, affecting subsequent performance. The resulting so-called \"binding effects\" are reliably observed in discrimination tasks. In contrast, in localization performance, these effects are absent and only inhibition of return (IOR) emerges - a location change benefit. Affective information has been found to modulate binding effects; yet a modulation of IOR has led to mixed results, with many finding no influence at all. In the current study, participants discriminated letters (Experiment 1) or localized dots (Experiment 2) on a touchpad in prime-probe sequences. During the prime display two images - one with fruits and one with a spider - appeared, one of which spatially congruent with the to-be-touched area. In the discrimination task, previously touching a spider compared to a fruit slowed down response repetitions. In contrast, the localization task only showed IOR. This suggests that task-irrelevant valence is integrated with the response and affects subsequent responses due to retrieval. However, this is not ubiquitous but depends on task type. The results shed further light on the impact of affective information on actions.

\"Inhibition of return\" (IOR) was originally described in the field of spatial attention, but it has also been observed in random number generation tasks. Subjects showed a tendency of \"repetition avoidance,\" which can be considered as equivalent to IOR in another cognitive domain. As temporal factors have been suspected to play an important role in random number generation, we aimed to examine how such factors might influence regularities such as repetition avoidance in random number generation tasks. Participants were instructed to verbally generate a sequence of numbers at a certain pace, that is, with either 0.5, 1.5, 3 or 4 s between each response. Each number in the sequence should have the same probability of appearance and should be independent from the others. However, it was observed that the human-generated sequences differed drastically from computer-simulated pseudo-random sequences. The distribution of the repetition gap, which indicates how many different numbers are reported between two identical numbers in the generated sequences, showed a \"three-phase\" characteristic: a phase of avoidance of the same number, an oscillatory component for coming back to the same number, and finally an exponential decay of number selection frequencies. This three-phase characteristic was independent of the time interval between responses. These observations indicate an item-based process in random number generation, making a time-based control in this task rather unlikely as has been hypothetically assumed.

Inhibition of return (IOR) has proved to be weakened by audiovisual integration because of the increased perceptual salience of targets. Although other audiovisual interactions, such as crossmodal correspondence, have also been shown to facilitate attentional processes, to the best of our knowledge, no study has investigated the interaction between crossmodal correspondence and IOR. The present study employed Posner\'s spatial cueing paradigm and manipulated the cue validity, crossmodal correspondence congruency and time interval of auditory and visual stimuli (AV interval) to explore the effect of crossmodal correspondence on the IOR effect. The behavioral results showed a reduced IOR effect under the correspondence congruency condition in contrast to the correspondence incongruency condition at the AV interval of 200 ms, whereas at an AV interval of 80 ms, the decreased IOR effect under crossmodal correspondence congruency was eliminated. The electrophysiological results showed a reduced amplitude difference in P2 between valid and invalid cue conditions when the crossmodal correspondence effect decreased the IOR effect. The present study provided the first evidence of the weakened effect of the crossmodal correspondence effect on the IOR effect, which could be eliminated by audiovisual integration.