The advancement of intelligent manufacturing technology in the era of Industry 5.0 has propelled the intelligence and automation of manufacturing production, while also exerting a significant impact on sustainable development of the manufacturing industry. However, the challenges and enablers faced by the transformation of intelligent manufacturing technology in the context of sustainable development of Industry 5.0 are still unclear. Based on literature review and expert opinions, this study uses the Likert scale to determine the challenges and enablers of the implementation of intelligent manufacturing technology in social, environmental and economic sustainability. The fuzzy-DEMETAL and AISM are used to analyze the logical relationship and hierarchical relationship between the above factors, and the MICMAC matrix is used to determine the key influencing factors. The research conclusions show that the most important challenges affecting the implementation of intelligent manufacturing technology are cost and funding, and the most important enabler is social benefits and public service improved. This research will provide insights for industry practitioners and decision makers in the management and decision-making process of implementing the transformation and upgrading of manufacturing intelligent manufacturing, thereby enhancing the sustainability of manufacturing development.

Introduction: In this work we explore a potential approach to improve human-robot collaboration experience by adapting cobot behavior based on natural cues from the operator. Methods: Inspired by the literature on human-human interactions, we conducted a wizard-of-oz study to examine whether a gaze towards the cobot can serve as a trigger for initiating joint activities in collaborative sessions. In this study, 37 participants engaged in an assembly task while their gaze behavior was analyzed. We employed a gaze-based attention recognition model to identify when the participants look at the cobot. Results: Our results indicate that in most cases (83.74%), the joint activity is preceded by a gaze towards the cobot. Furthermore, during the entire assembly cycle, the participants tend to look at the cobot mostly around the time of the joint activity. Given the above results, a fully integrated system triggering joint action only when the gaze is directed towards the cobot was piloted with 10 volunteers, of which one characterized by high-functioning Autism Spectrum Disorder. Even though they had never interacted with the robot and did not know about the gaze-based triggering system, most of them successfully collaborated with the cobot and reported a smooth and natural interaction experience. Discussion: To the best of our knowledge, this is the first study to analyze the natural gaze behavior of participants working on a joint activity with a robot during a collaborative assembly task and to attempt the full integration of an automated gaze-based triggering system.

With the advantages of new technologies and rising demand from customers, it is necessary to improve the manufacturing process. This necessity was recognized by the industry; therefore, the concept of Industry 4.0 has been implemented in various areas of manufacturing and services. The backbone and main aspect of Industry 4.0 is digitalization and the implementation of technologies into processes. While this concept helps manufacturers with the modernization and optimization of many attributes of the processes, Industry 5.0 takes a step further and brings importance to the human factor of industry practice, together with sustainability and resilience. The concept of Industry 5.0 contributes to the idea of creating a sustainable, prosperous, and human-friendly environment within companies. The main focus of the article is to analyze the existing literature regarding what is missing from the successful implementation of human centricity into industry practice, namely in small and medium-sized factories (SMEs). These findings are then presented in the form of requirements and barriers for the implementation of human centricity into SME factories, which can serve as guidelines for implementing human-centered manufacturing using axiomatic design theory in SMEs, which can serve as a roadmap for practitioners.

Industry 5.0 has the capacity to surpass the technology -oriented efficiency of Industry 4.0 and advance sustainable development objectives such as prioritizing human needs, ensuring socio-environmental sustainability, and enhancing resilience. Digital twins and simulation technologies improve manufacturing, evaluate products and operations, and predict any potential adverse consequences. With digital twin technology, everything that exists in the physical world will eventually be duplicated in the digital realm. Within the context of Industry 5.0, this study aims to investigate the impact of digital twin technology on the fan manufacturing sector. The proposal for implementing the enabling industry 5.0 application was presented to the chief engineers of eight distinct fan manufacturers. Out of these, five responded positively and their feedback was subsequently followed up on. Three different avenues such as production, supply chain, and testing transparency were proposed for industry 5.0 implementation. The exploration of testing transparency is being undertaken based on a consensual decision. The Web of Things standard that enables digital twin generation in industry 4.0 is implemented to enable the testing transparency. This data was linked with the internal digital twin of fan motor created using ANSYS. This digital twin can predict the lifespan of the motor by analyzing the temperature of the motor housing surface. Toward sustainability and resilience with Industry 4.0 and Industry 5.0 may provide insights into this alignment.

Industry 4.0 has led to digitalization and an increase in industrial activity. However, it has recently been recognized as inadequate for achieving European goals by 2030. Therefore, a novel Industry 5.0 paradigm has emerged in response to the unexpected negative effects caused by its predecessor. Industry 5.0 is mainly based on three foundational ideas: i) human-centrism, ii) resilience, and iii) sustainability. Human-centric solutions and human-machine-interaction; bio-inspired technologies and smart materials; real time-based digital twins and simulation; cyber safe data transmission, storage, and analysis; artificial intelligence; and energy efficiency and trustworthy autonomy have been recognized as the enabling technologies of this transformative vision. This paper outlines the protocol adopted to conduct a systematic literature review with the aim of exploring how the Architecture, Engineering, Construction, Management, Operation, and Conservation (AECMO&C) industry can adapt and be better prepared to embrace novel Industry 5.0 principles and enabling technologies, ultimately resulting in enhanced conservation practices for the built cultural heritage environment.
UNASSIGNED: The protocol has been registered on Open Science Framework (24/02/2024) and follows the PRISMA-P guidelines.
The arrival of \"Industry 4.0\" has brought a lot of changes to the way industries work, making them more digital. However, it hasn\'t been enough to meet Europe’s targets for 2030. As a result, a new concept called \"Industry 5.0\" has been created to fix some of the problems caused by Industry 4.0. Industry 5.0 is based on three main ideas. First, it focuses on people and how they interact with machines. Second, it aims to create systems that can recover from disruptions. Finally, it emphasizes the need to protect our environment while creating economic and social benefits. This new concept makes use of different technologies. These include solutions that focus on people and their interaction with machines, technologies inspired by nature, smart materials, virtual copies of physical systems that work in real time, secure data handling, artificial intelligence, and energy-saving measures. This paper outlines the method used to review a bunch of studies on how the industries of architecture, construction, engineering, management, operation, and conservation can adapt to Industry 5.0. The goal is to help these industries better preserve our cultural heritage buildings. The method used for this review has been officially registered and follows a set of guidelines called the PRISMA-P.

UNASSIGNED: Worldwide, the worker population age is growing at an increasing rate. Consequently, government institutions and companies are being tasked to find new ways to address age-related workforce management challenges and opportunities. The development of age-friendly working environments to enhance ageing workforce inclusion and diversity has become a current management and national policy imperative. Since an ageing workforce population is a spreading worldwide trend, an identification and analysis of worker age related best practices across different countries would help the development of novel palliative paradigms and initiatives.
UNASSIGNED: This study proposes a new systematic research-based roadmap that aims to support executives and administrators in implementing an age-inclusive workforce management program. The roadmap integrates and builds on published literature, best practices, and international policies and initiatives that were identified, collected, and analysed by the authors. The roadmap provides a critical comparison of age-inclusive management practices and policies at three different levels of intervention: international, country, and company. Data collection and analysis was conducted simultaneously across eight countries: Canada, France, Germany, Italy, Japan, New Zealand, Slovenia, and the USA.
UNASSIGNED: The findings of this research guide the development of a framework and roadmap to help manage the challenges and opportunities of an ageing workforce in moving towards a more sustainable, inclusive, and resilient labour force.

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Introduction: Flow state, the optimal experience resulting from the equilibrium between perceived challenge and skill level, has been extensively studied in various domains. However, its occurrence in industrial settings has remained relatively unexplored. Notably, the literature predominantly focuses on Flow within mentally demanding tasks, which differ significantly from industrial tasks. Consequently, our understanding of emotional and physiological responses to varying challenge levels, specifically in the context of industry-like tasks, remains limited. Methods: To bridge this gap, we investigate how facial emotion estimation (valence, arousal) and Heart Rate Variability (HRV) features vary with the perceived challenge levels during industrial assembly tasks. Our study involves an assembly scenario that simulates an industrial human-robot collaboration task with three distinct challenge levels. As part of our study, we collected video, electrocardiogram (ECG), and NASA-TLX questionnaire data from 37 participants. Results: Our results demonstrate a significant difference in mean arousal and heart rate between the low-challenge (Boredom) condition and the other conditions. We also found a noticeable trend-level difference in mean heart rate between the adaptive (Flow) and high-challenge (Anxiety) conditions. Similar differences were also observed in a few other temporal HRV features like Mean NN and Triangular index. Considering the characteristics of typical industrial assembly tasks, we aim to facilitate Flow by detecting and balancing the perceived challenge levels. Leveraging our analysis results, we developed an HRV-based machine learning model for discerning perceived challenge levels, distinguishing between low and higher-challenge conditions. Discussion: This work deepens our understanding of emotional and physiological responses to perceived challenge levels in industrial contexts and provides valuable insights for the design of adaptive work environments.

OCCUPATIONAL APPLICATIONSIn the context of Industry 5.0, our study advances manufacturing factory layout planning by integrating multi-objective optimization with nature-inspired algorithms and a digital human modeling tool. This approach aims to overcome the limitations of traditional planning methods, which often rely on engineers\' expertise and inputs from various functions in a company, leading to slow processes and risk of human errors. By focusing the multi-objective optimization on three primary targets, our methodology promotes objective and efficient layout planning, simultaneously considering worker well-being and system performance efficiency. Illustrated through a pedal car assembly station layout case, we demonstrate how layout planning can transition into a transparent, cross-disciplinary, and automated activity. This methodology provides multi-objective decision support, showcasing a significant step forward in manufacturing factory layout design practices.
Rationale: Integrating multi-objective optimization in manufacturing layout planning addresses simultaneous considerations of productivity, worker well-being, and space efficiency, moving beyond traditional, expert-reliant methods that often overlook critical design aspects. Leveraging nature-inspired algorithms and a digital human modeling tool, this study advances a holistic, automated design process in line with Industry 5.0. Purpose: This research demonstrates an innovative approach to manufacturing layout optimization that simultaneously considers worker well-being and system performance. Utilizing the Non-dominated Sorting Genetic Algorithm II (NSGA-II) and Particle Swarm Optimization (PSO) alongside a Digital Human Modeling (DHM) tool, the study proposes layouts that equally prioritize ergonomic factors, productivity, and area utilization. Methods: Through a pedal car assembly station case, the study illustrates the transition of layout planning into a transparent, cross-disciplinary, and automated process. This method offers objective decision support, balancing diverse objectives concurrently. Results: The optimization results obtained from the NSGA-II and PSO algorithms represent feasible non-dominated solutions of layout proposals, with the NSGA-II algorithm finding a solution superior in all objectives compared to the expert engineer-designed start solution for the layout. This demonstrates the presented method’s capacity to refine layout planning practices significantly. Conclusions: The study validates the effectiveness of combining multi-objective optimization with digital human modeling in manufacturing layout planning, aligning with Industry 5.0’s emphasis on human-centric processes. It proves that operational efficiency and worker well-being can be simultaneously considered and presents future potential manufacturing design advancements. This approach underscores the necessity of multi-objective consideration for optimal layout achievement, marking a progressive step in meeting modern manufacturing’s complex demands.

The bioprocessing industry is undergoing a significant transformation in its approach to quality assurance, shifting from the traditional Quality by Testing (QbT) to Quality by Design (QbD). QbD, a systematic approach to quality in process development, integrates quality into process design and control, guided by regulatory frameworks. This paradigm shift enables increased operational efficiencies, reduced market time, and ensures product consistency. The implementation of QbD is framed around key elements such as defining the Quality Target Product Profile (QTPPs), identifying Critical Quality Attributes (CQAs), developing Design Spaces (DS), establishing Control Strategies (CS), and maintaining continual improvement. The present critical analysis delves into the intricacies of each element, emphasizing their role in ensuring consistent product quality and regulatory compliance. The integration of Industry 4.0 and 5.0 technologies, including Artificial Intelligence (AI), Machine Learning (ML), Internet of Things (IoT), and Digital Twins (DTs), is significantly transforming the bioprocessing industry. These innovations enable real-time data analysis, predictive modelling, and process optimization, which are crucial elements in QbD implementation. Among these, the concept of DTs is notable for its ability to facilitate bi-directional data communication and enable real-time adjustments and therefore optimize processes. DTs, however, face implementation challenges such as system integration, data security, and hardware-software compatibility. These challenges are being addressed through advancements in AI, Virtual Reality/ Augmented Reality (VR/AR), and improved communication technologies. Central to the functioning of DTs is the development and application of various models of differing types - mechanistic, empirical, and hybrid. These models serve as the intellectual backbone of DTs, providing a framework for interpreting and predicting the behaviour of their physical counterparts. The choice and development of these models are vital for the accuracy and efficacy of DTs, enabling them to mirror and predict the real-time dynamics of bioprocessing systems. Complementing these models, advancements in data collection technologies, such as free-floating wireless sensors and spectroscopic sensors, enhance the monitoring and control capabilities of DTs, providing a more comprehensive and nuanced understanding of the bioprocessing environment. This review offers a critical analysis of the prevailing trends in model-based bioprocessing development within the sector.