impact analysis

  • 文章类型: Journal Article
    前所未有的2021年热穹顶在加拿大西部造成了广泛而持久的影响。包括不列颠哥伦比亚省619例确诊的与热有关的死亡,紧急医疗电话增加一倍,住院治疗增加,基础设施故障和对动植物的压力。然而,使用单一的事件后分析方法来捕获极端高温的各种社会经济后果可能是具有挑战性的。因此,有必要探索替代方法和数据源。以2021年的圆顶作为案例研究,使用来自5个订阅新闻数据库的在线新闻媒体文章(n=2909)和灰色文献检索进行了事件后分析,以确定加拿大极端高温事件的社会经济影响.文章报道了对自然环境的广泛影响(n=1366),社会基础设施和服务(n=1121),人类健康(n=1074),关键基础设施(n=988)和私营部门(n=165)。基于媒体的事件后分析捕捉到了各种影响,其中一些尚未通过其他数据源和方法确定。总的来说,我们表明,媒体分析可以补充传统的事件后分析方法,并为政府和公共卫生与安全官员提供更多的视角。
    The unprecedented 2021 Heat Dome caused wide-ranging and long-lasting impacts in western Canada, including 619 confirmed heat-related deaths in British Columbia, a doubling of emergency medical calls, increased hospitalisations, infrastructure failures and stress on plants and animals. However, such varied socio-economic consequences of extreme heat can be challenging to capture using a single post-event analysis method. Therefore, there is a need to explore alternative approaches and data sources. Using the 2021 Heat Dome as a case study, a post-event analysis using online news media articles (n = 2909) from 5 subscription news databases and a grey literature search was conducted to identify the socio-economic impacts of the extreme heat event in Canada. The articles reported a wide range of effects to the natural environment (n = 1366), social infrastructure and services (n = 1121), human health (n = 1074), critical infrastructure (n = 988) and the private sector (n = 165). The media-based post-event analysis captured various impacts, some of which have not been identified through other data sources and approaches. Overall, we show that media analysis can complement traditional post-event analysis methods and provide additional perspectives to governments and public health and safety officials.
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  • 文章类型: Case Reports
    这项研究旨在阐明先前报道的与运动相关的脑震荡(SRC)损伤的机制之间的差异,而在接触和碰撞运动中没有意识丧失与SRC损伤的机制之间的差异。根据男子艺术体操比赛中SRC受伤的两个视频(三人受伤),使用多体分析和8项脑损伤评估标准,根据各种参数估算SRC发生的风险.在本研究中,与先前报道的接触运动病例相比,男子艺术体操中发生的三种SRC影响在持续时间上表现出显著特征。这表明SRC的发生可能是由与在接触运动中引起SRC的不同类型的影响引起的(例如,tacking).此外,计算表明大脑变形率的应变表明,在所有涉及2型轴索损伤的病例中,存在神经肿胀的风险。因此,当重新检查运动相关的头部损伤时,重要的是要认识到SRC的特点和机制,发生在每个不同的运动,以及受伤后SRC的症状和病程。
    This study aimed to clarify the differences between the previously reported mechanisms of sports-related concussion (SRC) injuries without a loss of consciousness in contact and collision sports and the mechanisms of SRC injuries in our cases. Based on two videos of SRC injuries occurring during a men\'s rhythmic gymnastics competition (three people were injured), the risk of SRC occurrence was estimated from various parameters using a multibody analysis and eight brain injury evaluation criteria. In the present study, the three SRC impacts that occurred in men\'s rhythmic gymnastics showed significant characteristics in duration compared to previously reported cases in the contact sports. This suggests that the occurrence of SRC may have been caused by a different type of impact from that which causes SRC in contact sports (e.g., tackling). In addition, calculation of the strain indicating the rate of brain deformation suggested a risk of nerve swelling in all cases involving type 2 axonal injuries. Therefore, when reexamining sports-related head injuries, it is important to recognize the characteristics and mechanisms of SRC that occur in each different sport, as well as the symptoms and course of SRC after injury.
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  • 文章类型: Journal Article
    背景:此分析的目的是快速评估潜在成本,成本效益,以及多部门社区伙伴关系(MCP)通过解决健康的社会决定因素(SDOH)改善慢性病结局和促进健康公平的努力的长期影响。
    方法:2022年,评估人员与13个MCP合作,收集有关实施SDOH干预措施的启动和持续成本以及干预范围和时机的数据。2023年,该团队使用预防影响模拟模型(PRISM)来估计MCP努力超过5,10-,和20年的时期。该团队还分析了MCPs\'SDOH干预措施的成本和累计10年和20年的成本效益。
    结果:超过20年,由13个MCP实施的SDOH干预措施可以预防970例过早死亡,避免1.05亿美元的医疗费用和4.08亿美元的生产力损失。20年的累积结果显示,从医疗保健部门的角度来看,每质量调整生命年的潜在净成本为38300美元,并表明从社会角度来看,潜在的成本降低和健康结果改善。
    结论:这些发现有助于为未来SDOH干预措施的投资提供信息和支持。通过更好地了解启动和实施SDOH干预措施所需的成本,资助者和MCP可以为完成这项工作所需的资源做好准备。研究结果还表明,大多数MCP实施的SDOH干预措施具有良好的长期影响和潜在的成本效益。
    BACKGROUND: The purpose of this analysis was to rapidly evaluate the potential costs, cost-effectiveness, and long-term effects of efforts by multisector community partnerships (MCPs) to improve chronic disease outcomes and advance health equity by addressing social determinants of health (SDOH).
    METHODS: In 2022, the evaluators partnered with 13 MCPs to collect data on start-up and ongoing costs for implementing SDOH interventions and on intervention reach and timing. In 2023, the team used the Prevention Impacts Simulation Model to estimate the longer-term impact of MCPs\' efforts over 5-, 10-, and 20-year periods. The team also analyzed costs and cumulative 10- and 20-year cost-effectiveness of the MCPs\' SDOH interventions.
    RESULTS: Over 20 years, SDOH interventions implemented by the 13 MCPs can potentially prevent 970 premature deaths and avert $105 million in medical costs and $408 million in productivity losses. The 20-year cumulative results show potential net costs of $38,300 per quality-adjusted life-year gained from the healthcare sector perspective and indicate potentially reduced costs and improved health outcomes from the societal perspective.
    CONCLUSIONS: These findings can help inform and provide support for future investments in SDOH interventions. With a better understanding of costs needed to start up and implement SDOH interventions, funders, and MCPs can prepare for the resources required to do this work. Findings also suggest promising long-term impacts and potential cost-effectiveness for most MCP-implemented SDOH interventions.
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  • 文章类型: Journal Article
    有几种筛查工具可帮助普通神经科医师及时识别可能有资格转诊设备辅助治疗(DAT)的晚期帕金森病(PD)患者。然而,应该注意的是,并非所有这些临床决策规则都以彻底和一致的方式制定和验证.此外,仅进行了有限数量的头对头比较。现有研究表明,与5-2-1标准相比,D-DATS具有更高的阳性预测值和更高的特异性。而两种筛查工具的灵敏度相似。然而,关于决策规则的有效性,仍然没有回答的问题,例如验证研究的诊断性能指标是否可推广到其他人群。最终,问题是筛查工具能否有效地改善PD患者的生活质量.为了解决这个关键问题,应该进行影响分析。作者打算建立一个多国集群随机对照试验,以比较D-DATS和5-2-1标准对实施这些筛查工具的下游后果。特别关注对残疾和生活质量的影响。
    Several screening tools are available to assist general neurologists in the timely identification of patients with advanced Parkinson\'s disease (PD) who may be eligible for referral for a device-aided therapy (DAT). However, it should be noted that not all of these clinical decision rules have been developed and validated in a thorough and consistent manner. Furthermore, only a limited number of head-to-head comparisons have been performed. Available studies suggest that D-DATS has a higher positive predictive value and higher specificity than the 5-2-1 criteria, while the sensitivity of both screening tools is similar. However, unanswered questions remain regarding the validity of the decision rules, such as whether the diagnostic performance measures from validation studies are generalizable to other populations. Ultimately, the question is whether a screening tool will effectively and efficiently improve the quality of life of patients with PD. To address this key question, an impact analysis should be performed. The authors intend to set up a multinational cluster randomised controlled trial to compare the D-DATS and 5-2-1 criteria on the downstream consequences of implementing these screening tools, with a particular focus on the impact on disability and quality of life.
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  • 文章类型: Journal Article
    新冠肺炎疫情刺激了前所未有的数字化转变,促使远程医疗实践激增。本文通过对科学出版物的全面分析,探讨了大流行对远程医疗的影响。利用文献计量法,该研究调查了新冠肺炎发病前后远程医疗研究的趋势。在PubMed中进行的系统搜索产生了8,454份Covid-19之前的出版物(2016-2019年)和16,633份Covid-19之后的出版物(2020-2023年)。总共提取了21,989个不同的关键词。共现图揭示了不断演变的主题集群,在新冠肺炎之前,“mhealth”和“ehealth”占据主导地位,而“Covid-19”则成为大流行后的热门关键词。前10个关键词在Covid-19之后转移,反映了动态的研究重点。文献计量方法阐明了对大流行后远程医疗解决方案的高度探索,强调危机对学术话语的持久影响。关键术语的变化和关键术语排名的变化表明了动态的研究重点和对多维医疗保健挑战的更广泛考虑。承认研究的局限性,分析提供了一个高层次的视角,专注于作者的关键词。尽管面临挑战,这项研究提供了一个系统的概述,揭示了新的远程医疗应用领域的出现以及进一步深入分析的必要性。未来的研究方向可能会探索远程医疗应用的生态影响和其他有趣的方面,有助于全面理解远程医疗的学术轨迹。
    The Covid-19 pandemic spurred an unprecedented shift towards digitalization, prompting a surge in telehealth practices. This paper explores the impact of the pandemic on telemedicine through a comprehensive analysis of scientific publications. Utilizing a bibliometric approach, the study examines trends in telemedicine research before and after the onset of Covid-19. The systematic search in PubMed yielded 8,454 pre-Covid-19 publications (2016-2019) and 16,633 post-Covid-19 publications (2020-2023). A total of 21,989 distinct keywords were extracted. Co-occurrence maps reveal evolving thematic clusters, with \"mhealth\" and \"ehealth\" dominating pre-Covid-19, while \"Covid-19\" emerges as a top keyword post-pandemic. The Top-10 keywords shift post-Covid-19, reflecting dynamic research priorities. The bibliometric approach illuminates a heightened exploration of telehealth solutions post-pandemic, emphasizing the enduring impact of the crisis on academic discourse. Changes in key terms and shifts in key term ranking indicate dynamic research priorities and a broader consideration of multidimensional healthcare challenges. Acknowledging study limitations, the analysis offers a high-level perspective, focusing on authors\' keywords. Despite challenges, the study provides a systematic overview, revealing the emergence of new telemedicine application domains and the need for further in-depth analyses. Future research directions may explore the ecological impact of telemedicine applications and other intriguing aspects, contributing to a comprehensive understanding of telemedicine\'s scholarly trajectory.
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  • 文章类型: Journal Article
    背景:通过在称为“辅助”的插入器工具上施加连续冲击,可以将未骨水泥的股骨杆插入到骨骼中。影响分析已被证明是监测植入物插入并改善其主要稳定性的有前途的技术。
    方法:本研究旨在更好地了解锤子之间发生的动力学现象,辅助,在股骨柄插入过程中植入物和骨骼,验证植入物插入监测的影响分析的使用。提出了通过嵌塞协议插入股骨柄的动态3-D有限元模型。小梁骨杨氏模量(Et)的影响,过盈配合(IF),评估骨-植入物界面处的摩擦系数(μ)和对植入物插入和冲击力信号的冲击速度(v0)。
    结果:对于所有配置,在整个股骨柄插入过程中观察到冲击力信号的两个第一峰值之间的时间差的减小,阈值为0.23ms。达到该值所需的冲击次数取决于Et,对于本文所考虑的参数集,V0和IF在3和8之间变化。十次撞击后达到的骨-种植体接触比例在60%到98%之间变化,作为v0的函数增加,作为IF的函数减少,μ和Et.
    结论:这项研究证实了基于影响分析的方法监测植入物插入和检索骨-植入物接触特性的潜力。
    BACKGROUND: Uncemented femoral stem insertion into the bone is achieved by applying successive impacts on an inserter tool called \"ancillary\". Impact analysis has shown to be a promising technique to monitor the implant insertion and to improve its primary stability.
    METHODS: This study aims to provide a better understanding of the dynamic phenomena occurring between the hammer, the ancillary, the implant and the bone during femoral stem insertion, to validate the use of impact analyses for implant insertion monitoring. A dynamic 3-D finite element model of the femoral stem insertion via an impaction protocol is proposed. The influence of the trabecular bone Young\'s modulus (Et), the interference fit (IF), the friction coefficient at the bone-implant interface (μ) and the impact velocity (v0) on the implant insertion and on the impact force signal is evaluated.
    RESULTS: For all configurations, a decrease of the time difference between the two first peaks of the impact force signal is observed throughout the femoral stem insertion, up to a threshold value of 0.23 ms. The number of impacts required to reach this value depends on Et, v0 and IF and varies between 3 and 8 for the set of parameters considered herein. The bone-implant contact ratio reached after ten impacts varies between 60% and 98%, increases as a function of v0 and decreases as a function of IF, μ and Et.
    CONCLUSIONS: This study confirms the potential of an impact analyses-based method to monitor implant insertion and to retrieve bone-implant contact properties.
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  • 文章类型: Journal Article
    使用通过直接(溶剂)浸没退火(DIA)制备的醋酸纤维素复合材料证明了压力响应性颜色变化的被忽视机制,活性炭填料的不同负载量。即,半透明醋酸纤维素的压缩塑性变形导致光程长度的减少和不透明对比填料的可见性的伴随增加。含有1-7wt%活性炭的复合材料在12-56MPa的范围内表现出施加压力与所得压力标记亮度之间的线性关系。压力标记图案与横截面扫描电子显微镜(SEM)的比较支持由DIA产生的多孔形态对于调节压力指示器灵敏度的重要性。简单的落球测试用于说明这些指标在光学影响评估中的鲁棒性和实用性。
    A neglected mechanism for pressure-responsive color change is demonstrated using cellulose acetate composites prepared by direct (solvent) immersion annealing (DIA), with different loadings of activated charcoal filler. Namely, compressive plastic deformation of the translucent cellulose acetate leads to a decrease in the optical path length and a concomitant increase in the visibility of the opaque contrasting filler. Composites bearing 1-7 wt% activated charcoal exhibited a linear relationship between applied pressure and resulting pressure mark brightness in the range of 12-56 MPa. Comparison of pressure mark patterns with cross-sectional scanning electron microscopy (SEM) supports the importance of the porous morphology arising from DIA for the tuning of the pressure indicator sensitivity. A simple ball drop test is used to illustrate the robustness and utility of these indicators in optical impact assessment.
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  • 文章类型: Journal Article
    在各种医学领域,软组织硬度的变化与其生理病理演变有关。虽然弹性成像被广泛用于评估体内软组织硬度,它的应用需要复杂而昂贵的技术。这项研究的目的是确定是否可以采用基于影响分析的易于使用的方法来确定模仿体模的基于琼脂的软组织的浓度。对由质量浓度为1%至5%的琼脂制成的模仿体模的软组织进行了影响分析。从锤和与样品接触的小梁之间的冲击力信号的时间变化得出指标Δt。结果显示At作为琼脂浓度(以及因此样品硬度)的函数的非线性降低。Δt的值提供了对琼脂浓度的估计,误差为0.11%。基于冲击分析的方法对琼脂浓度的灵敏度与用弹性成像技术获得的结果具有相同的数量级。这项研究为影响分析的发展开辟了新的道路,容易和相对便宜的软组织弹性性能的临床评估。
    In various medical fields, a change of soft tissue stiffness is associated with its physio-pathological evolution. While elastography is extensively employed to assess soft tissue stiffness in vivo, its application requires a complex and expensive technology. The aim of this study is to determine whether an easy-to-use method based on impact analysis can be employed to determine the concentration of agar-based soft tissue mimicking phantoms. Impact analysis was performed on soft tissue mimicking phantoms made of agar gel with a mass concentration ranging from 1% to 5%. An indicator Δt is derived from the temporal variation of the impact force signal between the hammer and a small beam in contact with the sample. The results show a non-linear decrease of Δt as a function of the agar concentration (and thus of the sample stiffness). The value of Δt provides an estimation of the agar concentration with an error of 0.11%. This sensitivity of the impact analysis based method to the agar concentration is of the same order of magnitude than results obtained with elastography techniques. This study opens new paths towards the development of impact analysis for a fast, easy and relatively inexpensive clinical evaluation of soft tissue elastic properties.
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  • 文章类型: Review
    尽管预测模型有望识别出2型糖尿病高危人群,预测模型的实施状况还没有得到很好的检验。我们的审查表明,尽管正在开发的模型有所增加,但在实践中预测模型的实施仍然很低。
    Although a prediction model is expected to identify individuals who are at a high risk of type 2 diabetes, the implementation status of prediction models has not been well examined. Our review indicates that the implementation of predictive models in practice remains low despite the increase in models being developed.
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  • 文章类型: Journal Article
    近年来,由于对绿色和低碳能源转型与高质量经济社会增长之间关系的片面解释,一些过于理想化的应有性判断导致了理论的失败或与实践的偏离。选取2010-2020年中国30个省份的面板数据,因为中国在气候变化和全球能源安全方面扮演着不同的角色。本文对经济社会高质量增长和绿色低碳能源转型效率进行了界定和测度。在分析了能源转型的结构特征后,并讨论了转型效率对高质量增长的影响。结果表明,区域高质量增长从量变到质变的拐点尚未到来,而发达地区和发展中地区仍在努力解决明显的不平衡和不足问题。就目前而言,能源中心的能源过渡效率远高于能源负荷中心。具有能源供需平衡特征的省份已从绿色低碳发展的引入阶段无缝转向增长阶段。能源强度的降低和可再生能源份额的增加都能明显促进经济社会的高质量发展;但是,人均碳排放量的减少在短期内无法产生预期的正外部性。
    In recent years, because of the one-sided interpretation of the nexus between the green & low-carbon energy transition and the high-quality economic-social growth, some over-idealized due-oriented judgments have led to failures in theories or deviations from practices. It is necessary and typical to select the panel data of 30 provinces in China from 2010 to 2020 to demonstrate that nexus, since China plays a different role in both climate change and global energy security. This paper defines and measures both the high-quality economic-social growth and the green & low-carbon energy transition efficiency. After analyzing the structure characteristics of energy transition, it also discusses the impact of the transition efficiency on the high-quality growth. The results indicate that the inflection point from quantitative to qualitative change in the regional high-quality growth has not yet arrived, while the developed regions and the developing regions are still grappling with pronounced problems of imbalance and insufficiency. As far as now, the energy transition efficiency in the energy resource centers is much higher than that in the energy load centers. The provinces with a characteristic of energy supply-demand equilibrium have seamlessly shifted from the Introduction stage of green & low-carbon development to the Growth stage. Both the decrease in energy intensity and the increase in renewable share are able to promote high-quality economic-social development obviously; however, the reduction of per capita carbon emission cannot yield the expected positive externality in a short run.
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