新烟碱(NEO),用作防治蚜虫的杀虫剂,粉虱,鳞翅目,还有甲虫,对人类健康有许多有害影响,包括慢性病,癌症,不孕症,出生异常。监测食品中的残留是保证公众健康和生态平衡的必要条件。本工作验证了一种新的方法来测量七种新烟碱类杀虫剂(acetamipridACT,clothianidinCLT,dnotfuranDNT,吡虫啉IMD,NTP,噻虫啉TCP,和噻虫胺THT)在小麦中。分析程序基于使用固相萃取(SPE)去除干扰物并富集NEO的简单快速的小麦样品净化,通过反相色谱结合二极管阵列检测器(DAD)进行近地天体分离和定量。使用准确性配置文件策略验证了验证过程,一个简单的决策工具,基于方法的总误差(偏差加标准偏差)的度量。我们的研究结果证明,在未来,使用所提出的方法获得的结果中至少有95%将落在±15%的接受范围内。测试的成本效益,快速性,和简单性表明它用于确定啶虫脒的水平,clothianidin,dinotfuran,吡虫啉,尼坦吡喃,噻虫啉,和噻虫嗪在小麦常规分析中的应用。
Neonicotinoids (NEOs), used as insecticides against aphids, whiteflies, lepidopterans, and beetles, have numerous detrimental impacts on human health, including chronic illnesses, cancer, infertility, and birth anomalies. Monitoring the residues in food products is necessary to guarantee public health and ecological balance. The present work validated a new method to measure seven neonicotinoid insecticides (acetamiprid ACT, clothianidin CLT, dinotefuran DNT,
imidacloprid IMD, nitenpyram NTP, thiacloprid TCP, and thiamethoxan THT) in wheat. The analytical procedure was based on simple and fast wheat sample cleanup using solid-phase extraction (SPE) to remove interferents and enrich the NEOs, alongside the NEOs\' separation and quantification by reverse-phase chromatography coupled with a diode array detector (DAD). The validation process was validated using the accuracy profile strategy, a straightforward decision tool based on the measure of the total error (bias plus standard deviation) of the method. Our results proved that, in the future, at least 95% of the results obtained with the proposed method would fall within the ±15% acceptance limits. The test\'s cost-effectiveness, rapidity, and simplicity suggest its use for determining the levels of acetamiprid, clothianidin, dinotefuran,
imidacloprid, nitenpyram, thiacloprid, and thiamethoxam in routine analyses of wheat.