目的:报告使用iTrack微导管(NovaEyeMedical)作为独立手术或与白内障手术联合进行的ab-interno腔成形术的36个月有效性。
方法:单中心,回顾性病例系列。
方法:诊断为原发性开角型青光眼(POAG)的眼睛。
方法:将患有POAG的眼睛进行独立手术(单独使用iTrack)或与超声乳化术(iTrackphaco)联合进行ab-interno管成形术。
方法:主要结果是术后12、24和36个月的平均眼内压(IOP)降低和青光眼药物治疗的数量。次要终点包括视力和并发症发生率。
结果:包括44例开角型青光眼患者的44只眼:iTrack单独组23只眼,iTrack+phaco组21只眼。当两组一起分析时,12个月时IOP和用药数量均显著降低(P<0.0001),24和36个月时保持稳定.眼压从术前20.5±5.1mmHg下降至12、24和36个月时的13.3±2.1、13.1±2.4和13.3±2.1mmHg,分别;药物数量从术前的2.8±0.9减少到术后12、24和36个月的1.1±1.1、1.0±1.1和1.3±1.3,分别。在单独的iTrack和iTrack+phaco组中观察到了相当的IOP结果。从基线值20.9±6.1和20.0±3.9mmHg,分别,在36个月时达到13.2±2.1和13.5±2.2mmHg,分别。36个月时,95.5%的眼压≤17mmHg,68.2%的眼压≤1次。术中或术后均无严重并发症。
结论:发现使用iTrack微导管进行Ab-inter泪管成形术可有效降低IOP和药物依赖性。当作为独立手术或与白内障手术结合使用时,观察到了可比的结果。
OBJECTIVE: To report the 36-month effectiveness of ab-interno canaloplasty performed with the
iTrack microcatheter (Nova Eye Medical) as a standalone procedure or combined with cataract surgery.
METHODS: A single-center, retrospective case series.
METHODS: Eyes diagnosed with primary open-angle glaucoma (POAG).
METHODS: Eyes with POAG were treated with either ab-interno canaloplasty as a standalone procedure (iTrack alone) or in conjunction with phacoemulsification (
iTrack+phaco).
METHODS: The main outcomes were mean reductions in intraocular pressure (IOP) and numbers of glaucoma medications at 12, 24, and 36 months postoperatively. The secondary endpoints consisted of visual acuity and the rate of complications.
RESULTS: Forty-four eyes of 44 patients with open-angle glaucoma were included: 23 eyes in the iTrack-alone group and 21 eyes in the
iTrack+phaco group. When both groups were analyzed together, both the IOPs and numbers of medications were significantly reduced at 12 months (P < 0.0001) and remained stable at 24 and 36 months. IOPs decreased from 20.5 ± 5.1 mmHg preoperatively to 13.3 ± 2.1, 13.1 ± 2.4, and 13.3 ± 2.1 mmHg at 12, 24, and 36 months, respectively; the numbers of medications were reduced from 2.8 ± 0.9 preoperatively to 1.1 ± 1.1, 1.0 ± 1.1, and 1.3 ± 1.3 at 12, 24, and 36 months postoperatively, respectively. Comparable IOP results were observed in the
iTrack-alone and
iTrack+phaco groups, from baseline values 20.9 ± 6.1 and 20.0 ± 3.9 mmHg, respectively, to 13.2 ± 2.1 and 13.5 ± 2.2 mmHg at 36 months, respectively. At 36 months, 95.5% of eyes had an IOP of ≤ 17 mmHg and 68.2% of eyes were on ≤ 1 medication. No serious intraoperative or postoperative complications were reported.
CONCLUSIONS: Ab-interno canaloplasty performed with the
iTrack microcatheter was found to be effective in reducing IOP and medication dependence. Comparable results were observed when employed as a standalone procedure or when combined with cataract surgery.