慢性肌肉骨骼痛(CMP),定义为持续超过3个月的肌肉骨骼组织持续不适,全球约有17.1亿人口,导致严重的功能障碍和心理困扰,从而不利地影响个人的生活质量。这篇叙述性综述的目的是阐明饮食习惯之间的复杂关系,少肌症,和肠道菌群组成,着眼于加强患者管理和治疗效果。鉴于人们对饮食对CMP的影响越来越感兴趣,有必要对当前文献进行详细研究。营养摄入是肠道微生物群分布的关键决定因素,which,反过来,与肌肉组织的完整性和性能有关,有可能导致肌肉减少症.由于肌肉力量和功能的减弱,肌肉减少症的发展会加重CMP。此外,肠道微生物群的破坏可能直接调节伤害感受,加剧CMP的表现。因此,营养优化已成为CMP管理的可行方法。强调有利于健康肠道微生物组的饮食可以预防或减轻肌肉减少症,从而衰减CMP强度。然而,该领域需要进一步的实证探索,以解开这些相互作用的细微差别,并为CMP患者制定有效的饮食策略。除了单纯的镇痛,CMP的全面患者护理需要承认疼痛的复杂性和多因素性质及其基本要素。采用综合治疗模式使医疗保健从业者能够承诺更好的患者预后,丰富的生活质量,以及与CMP相关的持续医疗保健成本下降。
慢性肌肉骨骼疼痛(CMP)是骨骼的长期疼痛,肌肉,和关节,这是一个普遍的问题,影响着全世界超过17亿人。这种痛苦真的会扰乱一个人的日常生活,使日常工作变得困难,并造成很大的压力。这篇评论就像是对饮食习惯的深入研究,肌肉损失,生活在我们内脏中的微小生物都与这种疼痛有关。随着我们对食物如何影响CMP越来越好奇,仔细观察我们已经知道的东西很重要。我们吃的东西可以改变我们肠道中的小虫子,这对我们的肌肉有很大的影响。如果我们的肌肉变得虚弱和萎缩(一种称为肌少症的疾病),它会使CMP变得更糟,因为虚弱的肌肉不能很好地支撑我们的身体。此外,如果我们肠道中的虫子平衡失调,它甚至可能使我们感到更强烈的疼痛。所以,改变我们的饮食可能是解决CMP的好方法。吃让我们的肠道细菌快乐的食物可能有助于防止肌肉损失和减轻疼痛。但是我们仍然需要做更多的研究来更好地了解这一点,并找出为此目的吃的最佳食物。治疗CMP不仅仅是摆脱疼痛;它是关于查看整个情况以及所有导致疼痛的事情。通过考虑一切-从我们的饮食到我们的肌肉到我们的肠道细菌-医生可以帮助改善CMP患者的生活,让他们更舒适,从长远来看可能会降低医疗成本。
Chronic musculoskeletal pain (CMP), defined as persistent discomfort in musculoskeletal tissues persisting for over 3 months, afflicts an estimated 1.71 billion people globally, leading to significant functional impairments and psychological distress, thereby detrimentally affecting individuals\' quality of life. The objective of this narrative review is to elucidate the complex relationship among dietary habits, sarcopenia, and gut microbiota composition, with an eye toward enhancing patient management and outcomes. Given the burgeoning interest in the influence of diet on CMP, a detailed examination of the current literature is warranted. Nutritional intake is a critical determinant of the gut microbiota profile, which, in turn, is linked to musculature integrity and performance, potentially leading to sarcopenia. The development of sarcopenia can aggravate CMP owing to diminished muscular strength and functionality. Additionally, disruptions in the gut microbiota may directly modulate nociception, intensifying CMP manifestations. Thus, nutritional optimization emerges as a viable approach to CMP management. Emphasizing a diet conducive to a healthy gut microbiome could forestall or mitigate sarcopenia, thereby attenuating CMP intensity. Nevertheless, the domain calls for further empirical exploration to unravel the nuances of these interactions and to forge efficacious dietary strategies for individuals with CMP. Beyond mere analgesia, comprehensive patient care for CMP requires acknowledgment of the complex and multifactorial nature of pain and its foundational elements. Embracing an integrative treatment model allows healthcare practitioners to promise better patient prognoses, enriched life quality, and a decrease in the sustained healthcare costs associated with CMP.
Chronic musculoskeletal pain (CMP) is long-lasting pain in the bones, muscles, and joints, and it’s a common problem affecting over 1.7 billion people worldwide. This kind of pain can really disrupt someone’s daily life, making it hard to do everyday things and causing a lot of stress. This review is like a deep dive into how eating habits, muscle loss, and the tiny organisms living in our guts all connect to this pain. As we are becoming more curious about how food affects CMP, it’s important to look closely at what we already know. What we eat can change the tiny bugs in our guts, which has a big impact on our muscles. If our muscles get weak and shrink (a condition called sarcopenia), it can make CMP worse because weak muscles cannot support our bodies well. Also, if the balance of bugs in our gut is off, it might even make us feel pain more intensely. So, changing what we eat might be a good way to tackle CMP. Eating foods that keep our gut bugs happy might help prevent muscle loss and reduce pain. But we still need to do more research to understand this better and to figure out the best foods to eat for this purpose. Treating CMP is not just about getting rid of the pain; it’s about looking at the whole picture and all the things that contribute to the pain. By considering everything — from our diet to our muscles to our gut bugs — doctors can help improve the lives of people with CMP, making them more comfortable and possibly reducing medical costs in the long run.