high-risk pregnancy

高危妊娠
  • 文章类型: Journal Article
    青少年妊娠定义为10至19岁的年轻女性怀孕。青少年怀孕,这是发达国家和发展中国家关注的社会医疗保健问题之一,对母婴健康有负面影响。青春期的怀孕会使母亲和孩子的健康都处于危险之中,由于青春期怀孕的子痫发病率较高,全身性感染,低出生体重,与其他怀孕相比,早产。在这项研究中,教育水平的影响,吸烟,和婚姻状况对青少年妊娠的母婴结局进行了评估。
    对总共960名孕妇(480名15-19岁的怀孕青少年和480名20-26岁的怀孕成年妇女)的记录进行了回顾性检查。比较了各组的人口统计学数据以及妊娠的母婴结局。建立了逻辑回归模型,作为减少混杂效应的统计方法。
    未婚女性在青少年组中的患病率明显更高(38.3%vs.7.3%)。在考虑的风险因素中,先兆子痫(2.9%vs.0.8%)和吸烟(29.8%与9.8%)在青少年组中更常见。当两组在怀孕期间的危险因素方面进行比较时,研究发现,青春期怀孕与吸烟风险增加3.04倍有关,未婚风险高5.25倍,先兆子痫的风险高3.50倍,宫内发育迟缓(IUGR)的风险增加1.70倍。
    这项研究表明先兆子痫的风险增加,IUGR,青春期孕妇在怀孕期间吸烟。这些发现可用于识别需要特定援助的青少年怀孕,并采取措施降低不良后果的可能性。
    在这项研究中,我们研究了青少年怀孕的风险。青少年怀孕是一个公共卫生问题,在不发达国家或发展中国家更为普遍。我们认为,非政府组织和政府应该对青少年怀孕采取预防措施,并保护这个法律上脆弱的社会人口群体免于怀孕。为了更健康,更认真的怀孕经历,母亲必须有适当的年龄,已经过了青春期。青少年怀孕,伴随着许多风险,尤其是先兆子痫的风险,早产,和产妇死亡,应尽量减少或防止。
    UNASSIGNED: Adolescent pregnancy is defined as pregnancy occurring in young women between the ages of 10 and 19 years. Adolescent pregnancies, which are among the social healthcare concerns in developed and developing countries, have negative effects on maternal and infant health. Pregnancy in adolescence puts the health of both the mother and child at risk, as adolescent pregnancies have higher rates of eclampsia, systemic infection, low birth weight, and preterm delivery compared to other pregnancies. In this study, the effects of education level, smoking, and marital status on maternal and foetal outcomes in adolescent pregnancies were evaluated.
    UNASSIGNED: The records of a total of 960 pregnant women (480 pregnant adolescents aged 15-19 years and 480 pregnant adult women aged 20-26 years) were examined retrospectively. The demographic data of the groups and maternal and foetal outcomes of the pregnancies were compared. A logistic regression model was established as a statistical method for reducing confounding effects.
    UNASSIGNED: Unmarried women were statistically significantly more prevalent in the adolescent group (38.3% vs. 7.3%). Among the considered risk factors, preeclampsia (2.9% vs. 0.8%) and smoking (29.8% vs. 9.8%) were statistically significantly more common in the adolescent group. When the groups were compared in terms of risk factors in pregnancy, it was found that pregnancy in adolescence was associated with a 3.04-fold higher risk of smoking, 5.25-fold higher risk of being unmarried, 3.50-fold higher risk of preeclampsia, and 1.70-fold higher risk of intrauterine growth retardation (IUGR).
    UNASSIGNED: This study demonstrates an increased risk of preeclampsia, IUGR, and smoking during pregnancy in adolescent pregnant women. These findings can be used to identify adolescent pregnancies requiring specific assistance and to take measures to reduce the probability of adverse outcomes.
    In this study, we examine the risks of adolescent pregnancies. Adolescent pregnancy is a public health problem, and it is more common in underdeveloped or developing countries. We believe that non-governmental organisations and governments should take precautions regarding adolescent pregnancies and protect this legally vulnerable sociodemographic group from pregnancy. For healthier and more conscientious pregnancy experiences, mothers must be of appropriate age, having passed the period of adolescence. Adolescent pregnancies, which come with many risks, and especially risks of preeclampsia, premature birth, and maternal death, should be minimised or prevented.
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  • 文章类型: Case Reports
    嗜铬细胞瘤,一种罕见但可能严重的情况,在及时识别方面提出了挑战,特别是在怀孕期间,由于对妊娠相关高血压原因的误解。然而,阵发性症状增加诊断怀疑。诊断依赖于儿茶酚胺分泌过多的生化确认,然后进行肿瘤定位成像。在24周时或之后诊断时,建议在怀孕期间使用α-肾上腺素受体阻滞剂来管理儿茶酚胺过量,延迟肿瘤切除直至存活或分娩后。这种情况在怀孕期间的罕见,再加上诊断和管理方面的挑战,强调其对产科专业人员解决高血压控制的重要性,交货时间,和手术干预。
    Pheochromocytoma, a rare but potentially serious condition, poses challenges in timely identification, especially during pregnancy due to misconceptions about pregnancy-related hypertension causes. However, paroxysmal symptoms heighten diagnostic suspicion. The diagnosis relies on biochemical confirmation of catecholamine hypersecretion followed by imaging for tumor localization. When diagnosed at or after 24 weeks, alpha-adrenoceptor blockers are recommended during pregnancy to manage catecholamine excess, delaying tumor removal until viability or post-delivery. The rarity of this condition during pregnancy, coupled with diagnostic and management challenges, underscores its importance for obstetric professionals in addressing hypertensive control, delivery timing, and surgical intervention.
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  • 文章类型: Journal Article
    背景:这项前瞻性队列研究,从怀孕到产后六个月进行,并以STROBE方法为基础,定量探讨高危孕妇的产前母乳喂养意向与后续母乳喂养结果之间的关系,与低风险妊娠组相比。
    方法:这项研究是在阿提卡最大的公立医院之一进行的,该医院为孕妇提供护理。招募380名参与者,分为高风险(n=200)和低风险(n=180)队列。数据收集时间为20个月(从2020年5月底至2022年1月),从怀孕到产后六个月,通过全面的问卷。
    结果:统计分析显示,两组的产前母乳喂养意向和实际母乳喂养行为之间存在显著的相关性。具体来说,高危人群中81.1%的女性和低危人群中82.5%的女性表达了在怀孕期间纯母乳喂养的意图。产后六个月,54.9%的高风险和64.3%的低风险妊娠组设法维持母乳喂养。延长产前住院时间是一个具有统计学意义的因素(p=0.045),对高危妊娠的纯母乳喂养意愿产生负面影响。
    结论:研究结果阐明了产前意向对母乳喂养结局的关键影响,特别是在高危妊娠中。此外,该研究确定了长期住院对母乳喂养愿望的不利影响.这些见解强调了细微差别的必要性,旨在提高母乳喂养率的支持性干预措施,从而推进符合世界卫生组织建议的孕产妇和新生儿健康目标。
    BACKGROUND: This prospective cohort study, conducted from pregnancy to six months postpartum and grounded in STROBE methodology, quantitatively explores the relationship between antenatal breastfeeding intentions and subsequent breastfeeding outcomes among high-risk pregnant women, compared to a low-risk pregnancy group.
    METHODS: The study was conducted in one of the largest public hospitals in Attica that provides care to pregnant women, enrolling 380 participants divided into high-risk (n = 200) and low-risk (n = 180) cohorts. Data were collected over 20 months (starting from the end of May 2020 until January 2022), spanning from pregnancy to six months postpartum, via comprehensive questionnaires.
    RESULTS: Statistical analysis revealed a pronounced correlation between prenatal breastfeeding intentions and actual breastfeeding behaviors across both groups. Specifically, 81.1% of women in the high-risk group and 82.5% in the low-risk group expressed intentions of exclusively breastfeeding during pregnancy. By six months postpartum, 54.9% of the high-risk and 64.3% of the low-risk pregnancy group managed to sustain breastfeeding. Extended antenatal hospitalization emerged as a statistically significant factor (p = 0.045) negatively impacting exclusive breastfeeding intentions among high-risk pregnancies.
    CONCLUSIONS: The findings illuminate the critical influence of antenatal intentions on breastfeeding outcomes, particularly among high-risk pregnancies. Moreover, the study identifies the detrimental effect of prolonged hospital stays on breastfeeding aspirations. These insights underscore the necessity for nuanced, supportive interventions aimed at bolstering breastfeeding rates, thereby advancing maternal and neonatal health objectives aligned with World Health Organization recommendations.
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  • 文章类型: Case Reports
    一名41岁的妇女出现急性,妊娠37周时出现严重的左侧腹痛和呕吐。她的症状归因于肾绞痛,她接受了支持治疗。在她入院时,她开始自然分娩。由于其他产科适应症,该小组继续进行紧急剖腹产。术中,确定了坏死的左输卵管和卵巢,并诊断为附件扭转(AT)。去扭转时组织灌注没有恢复,并进行了左输卵管卵巢切除术。在怀孕期间AT是不寻常的,只有少数病例发生在妊娠晚期。这是一个具有挑战性的诊断,需要高度怀疑。超声和磁共振成像可能有助于建立诊断,但不应延迟明确的治疗。及时的手术干预对于防止卵巢组织的不可逆损伤至关重要。
    A 41-year-old woman presented with acute, severe left-sided abdominal pain and vomiting at 37 weeks\' gestation. Her symptoms were attributed to renal colic, and she was admitted for supportive treatment. During her admission, she went into spontaneous labour. Due to other obstetric indications, the team proceeded with delivery by emergency caesarean section. Intra-operatively, a necrotic left fallopian tube and ovary were identified, and a diagnosis of adnexal torsion (AT) was recognised. There was no return of tissue perfusion on de-torsion, and a left salpingo-oopherectomy was performed. AT in pregnancy is unusual, with only a minority of cases occurring in the third trimester. This is a challenging diagnosis to establish and requires a high index of suspicion. Ultrasound and magnetic resonance imaging can be helpful in establishing a diagnosis but should not delay definitive treatment. Prompt surgical intervention is paramount to prevent irreversible damage to ovarian tissue.
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  • 文章类型: Journal Article
    目的:描述诊断为恶性肿瘤的孕妇的妊娠结局和人工流产的发生率。
    方法:我们使用Merative™MarketScan®ResearchDatabases的美国索赔数据,在2015年第四季度至2020年12-55岁的私人保险人群中进行了一项回顾性队列研究。我们包括七个州的怀孕,这些州的私人堕胎保险有优惠政策。
    结果:183,685例妊娠中有1,471例(0.8%)被诊断为癌症。在接受抗癌治疗的人中,21.6%(95CI:14.4-30.4%)进行了人工流产,而没有癌症诊断的孕妇为10.9%(95CI:10.8-11.1%)。
    结论:堕胎限制可能会影响许多在妊娠早期需要癌症治疗的孕妇。
    这项研究使用了MarketScan®研究数据库,这是Merative™的专有数据库。我们的数据使用协议条件禁止我们共享数据。希望获得MarketScan研究数据库的研究人员可以联系Merative™。
    OBJECTIVE: This study aimed to characterize pregnancy outcomes and the incidence of induced abortion among pregnant people with a diagnosis of malignancy.
    METHODS: We conducted a retrospective cohort study among privately insured people aged 12 to 55 years from the fourth quarter of 2015-2020 using US claims data from Merative MarketScan Research Databases. We included pregnancies from seven states with favorable policies for private insurance coverage of abortion.
    RESULTS: There were 1471 of 183,685 (0.8%) pregnancies with a cancer diagnosis. Among those receiving anticancer therapy, 21.6% (95% CI: 14.4-30.4%) underwent induced abortion compared with 10.9% (95% CI: 10.8-11.1%) of pregnant patients without a cancer diagnosis.
    CONCLUSIONS: Abortion restrictions may affect many pregnant women requiring cancer treatment in early pregnancy.
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  • 文章类型: Journal Article
    背景:加强母乳喂养实践,即使在富裕国家,大大降低了儿童死亡率。然而,五分之三的新生儿在出生后的第一个小时内没有接受母乳喂养。研究表明,在高风险怀孕的情况下,在开始和维持母乳喂养方面可能存在挑战.高危妊娠出生的婴儿特别容易患病和死亡。尽管母乳喂养是预防各种婴儿和婴儿期后疾病的保护措施,许多母亲在开始或维持母乳喂养时遇到困难,原因是与她们的状况相关的并发症。本研究旨在阐明高危妊娠母亲对母乳喂养的理解和经验。考虑到伊朗的文化和社会背景。
    方法:本研究是一项利用常规内容分析方法的定性研究。在这项定性研究中,将通过有目的和滚雪球抽样选择经历过高风险怀孕并目前有6个月以下婴儿的母亲。他们的母乳喂养经验将通过个人收集,半结构化,和面对面的采访。除了面试,观察组和焦点组也将用于收集数据。数据分析采用Graneheim和Lundman's方法,MAXQDA软件版本10,VERBISoftwareGmbH,柏林。该研究将利用Lincoln和Guba(1985)的有效性和可靠性标准。
    结论:这项定性研究旨在调查高危妊娠母亲母乳喂养的经历和挑战,以查明这一人群中的母乳喂养障碍,并制定解决这些障碍的必要干预措施和策略。
    BACKGROUND: Enhancing breastfeeding practices, even in affluent nations, significantly reduces child mortality rates. Nevertheless, three out of five newborns do not receive breastfeeding within the first hour of birth. Research indicates that under high-risk pregnancy circumstances, there may be challenges in initiating and sustaining breastfeeding. Infants born from high-risk pregnancies are particularly vulnerable to illnesses and mortality. Although breastfeeding serves as a protective measure against various infant and post-infancy ailments, many mothers encounter difficulties in commencing or maintaining breastfeeding due to complications associated with their conditions. The present study aims to illuminate the understanding and experience of breastfeeding in mothers with high-risk pregnancies, considering the cultural and social context of Iran.
    METHODS: This study is a qualitative research utilizing a conventional content analysis approach. In this qualitative study, mothers who have undergone a high-risk pregnancy and currently have infants under 6 months old will be chosen through purposeful and snowball sampling. Their breastfeeding experiences will be gathered through individual, semi-structured, and face-to-face interviews. In addition to interviews, observation and focus groups will also be used to collect data. Data analysis was performed using Graneheim and Lundman\'s method with MAXQDA software version 10, VERBI Software GmbH, Berlin. The study will utilize the criteria of Lincoln and Guba (1985) for validity and reliability.
    CONCLUSIONS: This qualitative study aims to investigate the experiences and challenges of breastfeeding in mothers with high-risk pregnancies to pinpoint breastfeeding barriers in this demographic and develop essential interventions and strategies to address these obstacles.
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  • 文章类型: Case Reports
    一名22岁的孕妇在经历了与溶血有关的子痫发作后,从外部医疗机构转移过来,肝酶升高和低血小板计数综合征(HELLP)综合征,和后部可逆性脑病综合征(PRES)。她的情况因宫内胎儿死亡和弥散性血管内凝血而更加复杂,需要采取全面的多学科方法。本报告详细介绍了在管理这种具有不同医疗要求的复杂患者方面的诊断过程和挑战。重点放在观察到的止血异常上,我们描绘了我们的方法中的细微差别相比,管理一个非妊娠患者的类似情况。提高医疗保健专业人员的意识对于及时诊断和有效干预妊娠期间这种罕见的神经系统并发症至关重要。
    A 22-year-old pregnant woman was transferred from an external medical facility after experiencing an eclamptic seizure linked to hemolysis, elevated liver enzymes and low platelet count syndrome (HELLP) syndrome, and posterior reversible encephalopathy syndrome (PRES). Her situation was further complicated by intrauterine fetal demise and disseminated intravascular coagulation, necessitating a comprehensive multidisciplinary approach. This report details the diagnostic process and challenges in managing this complex patient with diverse medical requirements. Emphasis is placed on the observed hemostatic abnormalities, and we delineate the nuances in our approach compared to managing a similar condition in a nonpregnant patient. Heightened awareness among healthcare professionals is imperative for prompt diagnosis and effective intervention in such uncommon neurological complications during pregnancy.
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  • 文章类型: Journal Article
    目的:健康相关生活质量(HRQoL)对于高危孕妇及其配偶至关重要。本研究旨在探讨自我效能感之间的二元关联(包括演员和伴侣效应),二元应对,和高危孕妇及其配偶的HRQoL,并检查二元应对的中介作用。
    方法:这项横断面研究从2022年10月至2023年9月招募了来自中国两家三级甲等医院的参与者。包括中文版一般自我效能感量表在内的问卷,二元应对库存,调查使用了12份简短的健康调查量表。构建了行为者-伴侣相互依存中介模型,以检验二元关联和中介效应。
    结果:在演员效果中,自我效能感与二元应对、HRQoL呈正相关(P<0.05)。关于合作伙伴的影响,孕妇的自我效能感与配偶的二元应对和身体健康呈正相关(P<0.05)。二重应对部分介导了两组自我效能感与HRQoL的关系(P<0.05)。
    结论:高危孕妇及其配偶的HRQoL需要紧急关注。增强这些夫妇的自我效能感和二元应对与他们改善的身心健康有关。医疗保健专业人员应考虑夫妻之间的互动,并将它们一起纳入围产期护理。基于现有的积极心理学和二元干预措施的夫妻或家庭干预计划可能会共同努力,以改善夫妻的HRQoL。
    OBJECTIVE: Health-related quality of life(HRQoL) is essential for high-risk pregnant women and their spouses. This study aimed to explore the dyadic associations (including actor and partner effects) among self-efficacy, dyadic coping, and HRQoL of high-risk pregnant women and their spouses and examine the mediating effect of dyadic coping.
    METHODS: This cross-sectional study recruited participants from two Grade A tertiary hospitals in China from October 2022 to September 2023. A questionnaire including the Chinese version of the General Self-Efficacy Scale, Dyadic Coping Inventory, and 12 Short Form Health Survey Scales was used for the survey. The actor-partner interdependence mediation model was constructed to test dyadic associations and mediating effects.
    RESULTS: In the actor effects, self-efficacy was positively associated with dyadic coping and HRQoL (P < 0.05). Regarding partner effects, pregnant women\'s self-efficacy was positively associated with spouses\' dyadic coping and physical health (P < 0.05). Dyadic coping partially mediated the relationship between self-efficacy and HRQoL for both groups(P < 0.05).
    CONCLUSIONS: The HRQoL of high-risk pregnant women and their spouses requires urgent attention. Enhancing self-efficacy and dyadic coping in these couples is related to their improved physical and mental health. Healthcare professionals should consider interactions between couples and include them together in perinatal care. Intervention programs for couples or families based on existing positive psychology and dyadic interventions may work together to improve the HRQoL of couples.
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  • 文章类型: Journal Article
    背景技术高危妊娠的特征在于对孕产妇和新生儿健康结局构成潜在风险的各种因素。及早发现这些高危妊娠是预防孕产妇死亡率和发病率的关键第一步,从而促进母亲和婴儿的整体健康。这项研究旨在评估高危妊娠的发生,并调查孕妇中与之相关的因素。方法在泰米尔纳德邦地区政府医院妇产科门诊部进行描述性调查,涉及1889名孕妇在他们的第二和第三个三个月。结构化问卷,根据印度国家卫生门户网站概述的印度标准标准构建,作为数据收集工具。该调查于2022年2月和3月进行,在此期间对孕妇进行了采访。随后,对收集的数据进行描述性和推断性统计分析.结果在调查的1889名孕妇中,29%(n=530)被列为高危妊娠。在这个群体中,34.3%(n=182)被诊断为甲状腺功能减退症,而23.2%(n=123)的人经历了妊娠高血压。观察到与高危妊娠的显着关联,如年龄,教育状况,职业,家庭收入,社会经济地位,孕妇中还有Gravida.结论政策制定者必须紧急实施循证干预措施,旨在早期发现和治疗高危妊娠。这种积极的方法对于预防孕产妇死亡率和发病率至关重要。
    Background High-risk pregnancies are characterized by various factors that pose potential risks to maternal and newborn health outcomes. Early detection of these high-risk pregnancies serves as a crucial initial step in preventing maternal mortality and morbidity, thereby promoting the overall health of both mother and baby. This study sought to assess the occurrence of high-risk pregnancy and investigate the factors associated with it among pregnant women. Methods A descriptive survey was undertaken at the Obstetrics and Gynaecology outpatient department of a District Government Hospital in Tamil Nadu, involving 1889 pregnant women in their second and third trimesters. A structured questionnaire, constructed following the Indian standard criteria outlined by the National Health Portal of India, served as the data collection tool. The survey was conducted in February and March 2022, during which pregnant women were interviewed. Subsequently, the collected data underwent descriptive and inferential statistical analysis. Results Among the 1889 pregnant women surveyed, 29% (n=530) were classified as high-risk pregnancies. Within this group, 34.3% (n=182) were diagnosed with hypothyroidism, while 23.2% (n=123) experienced pregnancy-induced hypertension. Significant associations with high-risk pregnancy were observed for factors such as age, education status, occupation, family income, socioeconomic status, and gravida among the pregnant women. Conclusion Policymakers must urgently implement evidence-based interventions aimed at early detection and treatment of high-risk pregnancies. This proactive approach is essential in preventing maternal mortality and morbidity.
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  • 文章类型: Systematic Review
    患有肺动脉高压(PH)的妇女在怀孕和围产期的死亡率增加。越来越多的出版物表明产妇结局有所改善,因此,我们对疾病严重程度和产妇生存率进行了系统评价。在筛选了1967年至2021年的9097项潜在研究后,我们确定了66篇相关出版物。结果随着时间的推移不断改善,死亡率从2015年之前发表的研究的11.6%下降到2015年之后发表的研究的8.2%。轻度疾病患者(0.8%)的死亡率低于艾森曼格综合征患者(26.2%)或特发性肺动脉高压患者(7.4-24.0%)。已发表的研究的一个主要缺点是它们使用超声心动图估计的肺动脉压来定义严重程度,不考虑更多当代参数。本系统综述为孕前咨询与PH相关的妊娠风险提供了新的见解,并建议在确定个体的妊娠相关风险时应仔细考虑PH分类和严重程度。
    Women with pulmonary hypertension (PH) have increased mortality during pregnancy and the peripartum period. An increasing number of publications suggest improvements in maternal outcomes, so we conducted a systematic review focusing on disease severity and maternal survival. After screening 9097 potential studies from 1967 to 2021, we identified 66 relevant publications. Outcomes improved continuously over time and mortality fell from 11.6% in studies published before 2015 to 8.2% in studies published after 2015. Mortality was lower in patients with mild disease (0.8%) than in those with Eisenmenger syndrome (26.2%) or idiopathic pulmonary arterial hypertension (7.4-24.0%). One major drawback of the published studies is that they define severity using echocardiographic-estimated pulmonary artery pressures, without considering more contemporary parameters. This systematic review provides new insights for preconception counseling on pregnancy risks related to PH and suggests that PH classification and severity should be carefully considered in determining an individual\'s pregnancy-associated risk.
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