heat balance

热平衡
  • 文章类型: Journal Article
    在严重的环境高温事件中,65岁以上的人是最脆弱的人群,经历比任何其他年龄组更糟糕的健康结果。老年女性的风险高于年龄匹配的男性;然而,这是否反映了女性对热的更高易感性或仅仅是人群性别比例尚不清楚.72名40-92岁的参与者(29M/43F)以旨在反映日常生活活动的代谢率暴露于进行性热应激。在干热(HD;最高53°C;≤25%rh)和温暖潮湿(WH;〜35°C;≥50%rh)的环境中进行了实验。在确定每个条件的临界极限之后,进行正向逐步多元线性回归分析,首先将净代谢率(Mnet)和年龄输入模型,其次是性,体重(mb),V♪o2max,体表面积,和LDL胆固醇。在考虑了Mnet和年龄之后,性别进一步改善了HD环境(R2adj=0.34,p<0.001)和WH环境(R2adj=0.36,P<0.005)下的回归模型。性别解释了HD条件下临界环境极限变化的约15%和WH条件下的12%。在WH(p=0.007,p=0.03)和HD(p=0.001,p=0.01)环境中,与中年女性和老年男性相比,老年女性的热补偿性曲线向左移动,表明年龄和性别依赖性热脆弱性。这反映了相对于年轻人而言,与衰老相关的热平衡阈值的异质性,并表明老年女性比年龄匹配的男性更容易受到伤害。
    Individuals over the age of 65 are the most vulnerable population during severe environmental heat events, experiencing worse health outcomes than any other age cohort. The risk is greater in older women than in age-matched men; however, whether that reflects a greater susceptibility to heat in women or simply population sex proportionality is unclear. Seventy-two participants (29 M/43 F) aged 40-92 yrs were exposed to progressive heat stress at a metabolic rate designed to reflect activities of daily living. Experiments were conducted in both hot-dry (HD; up to 53°C; ≤25% rh) and warm-humid (WH; ~35°C; ≥50% rh) environments. After determining critical limits for each condition, forward stepwise multiple linear regression analyses were conducted with net metabolic rate (Mnet) and age entered into the model first, followed by sex, body mass (mb), V̇o2max, body surface area, and LDL cholesterol. After accounting for Mnet and age, sex further improved the regression model in the HD environment (R2adj = 0.34, p < 0.001) and WH environment (R2 adj = 0.36, P < 0.005). Sex explained approximately 15% of the variance in critical environmental limits in HD conditions and 12% in WH conditions. Heat compensability curves were shifted leftward for older women indicating age and sex-dependent heat vulnerability compared to middle-aged women and older men in WH (p=0.007, p=0.03) and HD (p=0.001, p=0.01) environments. This reflects the heterogeneity of thermal-balance thresholds associated with aging relative to those seen in young adults and suggests that older females are more vulnerable than their age-matched male counterparts.
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  • 文章类型: Journal Article
    冰-海洋阻力系数Cw和转角θw是冰-海洋耦合模拟中的关键参数,确定两种介质之间的动量传递。无论冰海界面的静态稳定性如何,这些参数通常都被视为常数。本研究基于对热能和动能平衡的直接观察,研究了Cw和θw的变异性。在从消融到重新冻结的过渡期间,在整个北极中部广泛的多年冰袋下进行了观测,表明在5m深度处Cw=1-130×10-3和θw=-19-1°的显着变异性。比较不同的站点,观察结果表明,Cw对机械和浮力强迫产生的稳定性参数(μ)具有明显的依赖性。Cw随着μ的增加而迅速衰减,表明在中性或不稳定条件下,冰到海洋的动量转移得到增强,而在稳定的条件下被削弱。此外,观察到的电流垂直剖面表明,|θw|在不稳定的情况下倾向于更小,在稳定的情况下倾向于更大。我们建议使用恒定值进行数值模拟可能会导致低估冰生长期的大规模近地表电流。
    The ice-ocean drag coefficient C w and turning angle θ w are crucial parameters in ice-ocean coupled simulations, determining the transfer of momentum between the two media. These parameters are often treated as constants regardless of the static stability at the ice-ocean interface. This study investigates the variability of C w and θ w based on direct observations of thermal and kinetic energy balance. The observations were conducted beneath multiyear ice packs widely across the central Arctic during a period transitioning from ablation to refreezing, indicating significant variability of C w  = 1-130 × 10-3 and θ w  =  - 19-1° at 5 m depth. Comparing different stations, the observations suggest a pronounced dependence of C w on the stability parameter ( μ ) resulting from mechanical and buoyant forcing. C w rapidly decays with increasing μ , indicating that the ice-to-ocean momentum transfer is enhanced for neutral or unstable conditions, while it is weakened for stable conditions. In addition, observed vertical profiles of currents revealed that | θ w | tends to be smaller for unstable and larger for stable conditions. We suggest that numerical simulations using constant values could result in an underestimate of large-scale near-surface currents during the ice growing period.
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  • 文章类型: Journal Article
    频率,持续时间,极端高温事件的严重程度有所增加,预计在下个世纪将继续增加。因此,在这些极端高温事件期间,过度高温和心血管相关的发病率和死亡率的风险增加.因此,这项调查的目的是建立(1)中年人(MA)的临界环境核心温度(Tc)限值,(2)导致心率(HR)逐渐上升的MA和老年人(O)的环境阈值,(3)检查整个成年年龄范围内的关键环境Tc限制和HR环境阈值。33名青年(Y)(15F;23±3年),28MA(17F;51±6年),和31O(16F;70±3年)受试者在温暖潮湿的环境室中暴露于进行性热应激(WH,34-36°C,50-90%Rh)和干热(HD,38°C-52°C,<30%rh)环境,同时以低代谢率运动,反映日常生活活动(〜1.8METS)。在这两种环境中,年龄对临界环境Tc限值和环境HR阈值有主要影响(年龄的主要影响均p<0.001)。在整个生命周期中,在HD环境中,临界环境Tc和HR阈值随年龄线性下降(R2≥0.3),并且在WH环境中曲线早期(R2≥0.4)。这些数据支持关键环境Tc限值和HR阈值向较低环境条件的年龄相关转变,并可用于制定基于证据的安全指南,以最大程度地减少整个成人年龄范围内未来与热相关的发病率和死亡率。
    The frequency, duration, and severity of extreme heat events have increased and are projected to continue to increase throughout the next century. As a result, there is an increased risk of excessive heat- and cardiovascular-related morbidity and mortality during these extreme heat events. Therefore, the purposes of this investigation were to establish 1) critical environmental core temperature (Tc) limits for middle-aged adults (MA), 2) environmental thresholds that cause heart rate (HR) to progressively rise in MA and older (O) adults, and 3) examine critical environmental Tc limits and HR environmental thresholds across the adult age span. Thirty-three young (Y) (15 F; 23 ± 3 yr), 28 MA (17 F; 51 ± 6 yr), and 31 O (16 F; 70 ± 3 yr) subjects were exposed to progressive heat stress in an environmental chamber in a warm-humid (WH, 34-36°C, 50-90% rh) and a hot-dry (HD, 38°C-52°C, <30% rh) environment while exercising at a low metabolic rate reflecting activities of daily living (∼1.8 METs). In both environments, there was a main effect of age on the critical environmental Tc limit and environmental HR thresholds (main effect of age all P < 0.001). Across the lifespan, critical environmental Tc and HR thresholds decline linearly with age in HD environments (R2 ≥ 0.3) and curvilinearly in WH environments (R2 ≥ 0.4). These data support an age-associated shift in critical environmental Tc limits and HR thresholds toward lower environmental conditions and can be used to develop evidence-based safety guidelines to minimize future heat-related morbidity and mortality across the adult age span.NEW & NOTEWORTHY This study is the first to identify critical environmental core temperature and heart rate thresholds across the adult age spectrum. In addition, our data demonstrate that the rate of decline in Tc and HR limits with age is environmental-dependent. These findings provide strong empirical data for the development of safety guidelines and policy decisions to mitigate excessive heat- and cardiovascular-related morbidity and mortality for impending heat events.
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  • 文章类型: Journal Article
    我们的目标是开发和验证中高强度户外自行车和跑步的单独的全身出汗率预测方程,使用简单的测量或估计的活动和环境输入。在澳大利亚的两个收集地点,182个室外跑步试验,158个室外自行车试验在湿球温度范围从~15℃到~29℃的条件下完成,在每个试验中测量〜60分钟的全身出汗率。数据随机分为模型开发(跑步:120;循环:100个试验)和验证组(跑步:62;循环:58个试验),使专有的预测模型被开发,然后验证。当当地测量的环境条件用参与者对黑球温度的主观评分代替时,还开发并测试了跑步和骑行模型。风速,和湿度。对于跑步和自行车模型,预测出汗率的平均绝对误差为0.03和0.02L·h-1,分别。跑步(0.44和-0.38L·h-1)和循环(0.45和-0.42L·h-1)的95%置信区间在可接受的范围内,在3小时内总体重的等效变化为±2%。预测模型描述的观察到的出汗的个体差异为跑步和骑自行车的77%和60%,分别。用气候特征的主观评估代替测量的环境变量,使运行模型描述的观察到的出汗变化减少了约25%,但自行车模型只有2%左右。这些预测模型是公开访问的(https://sweatratecalculator.com),可以在户外跑步和骑自行车之前指导个性化的水合管理。
    Our aim was to develop and validate separate whole body sweat rate prediction equations for moderate to high-intensity outdoor cycling and running, using simple measured or estimated activity and environmental inputs. Across two collection sites in Australia, 182 outdoor running trials and 158 outdoor cycling trials were completed at a wet-bulb globe temperature ranging from ∼15°C to ∼29°C, with ∼60-min whole body sweat rates measured in each trial. Data were randomly separated into model development (running: 120; cycling: 100 trials) and validation groups (running: 62; cycling: 58 trials), enabling proprietary prediction models to be developed and then validated. Running and cycling models were also developed and tested when locally measured environmental conditions were substituted with participants\' subjective ratings for black globe temperature, wind speed, and humidity. The mean absolute error for predicted sweating rate was 0.03 and 0.02 L·h-1 for running and cycling models, respectively. The 95% confidence intervals for running (+0.44 and -0.38 L·h-1) and cycling (+0.45 and -0.42 L·h-1) were within acceptable limits for an equivalent change in total body mass over 3 h of ±2%. The individual variance in observed sweating described by the predictive models was 77% and 60% for running and cycling, respectively. Substituting measured environmental variables with subjective assessments of climatic characteristics reduced the variation in observed sweating described by the running model by up to ∼25%, but only by ∼2% for the cycling model. These prediction models are publicly accessible (https://sweatratecalculator.com) and can guide individualized hydration management in advance of outdoor running and cycling.NEW & NOTEWORTHY We report the development and validation of new proprietary whole body sweat rate prediction models for outdoor running and outdoor cycling using simple activity and environmental inputs. Separate sweat rate models were also developed and tested for situations where all four environmental parameters are not available, and some must be subsequently estimated by the user via a simple rating scale. All models are freely accessible through an online calculator: https://sweatratecalculator.com. These models, via the online calculator, will enable individualized hydration management for training or recreational cycling or running in an outdoor environment.
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  • 文章类型: Journal Article
    本研究利用神经网络来检测和定位低压汽轮机的热异常,其中一些经历了效率下降。由于在存在线性和强关系的情况下难以捕获非线性和弱关系,因此依赖于专家知识或统计方法的标准方法难以识别异常蒸汽管线。在这项研究中,一些与产出呈线性关系的投入被有意忽略。其余输入已用于使用测量数据训练浅层前馈或长短期记忆神经网络。由此产生的模型已经通过Shapley加法解释进行了分析,它可以确定单个输入或模型特征对输出的影响。此分析确定了不应连接的线之间的意外关系。随后,在定期关闭工厂期间,在指示的管线中发现了泄漏。
    This study utilizes neural networks to detect and locate thermal anomalies in low-pressure steam turbines, some of which experienced a drop in efficiency. Standard approaches relying on expert knowledge or statistical methods struggled to identify the anomalous steam line due to difficulty in capturing nonlinear and weak relations in the presence of linear and strong ones. In this research, some inputs that linearly relate to outputs have been intentionally neglected. The remaining inputs have been used to train shallow feedforward or long short-term memory neural networks using measured data. The resulting models have been analyzed by Shapley additive explanations, which can determine the impact of individual inputs or model features on outputs. This analysis identified unexpected relations between lines that should not be connected. Subsequently, during periodic plant shutdown, a leak was discovered in the indicated line.
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  • 文章类型: Journal Article
    我们使用热成像和热平衡模型来检查野生哺乳动物的热生态学,以昼夜有袋动物(Myrmecobiusfasciatus)为模型。在11.7-29°C和16.4-49.3°C的环境湿球温度下,使用红外热像法测量体表温度,分别;表面温度随不同身体部位和环境温度而变化。辐射和对流热交换随环境条件以及反映其形状的各种身体表面而显着变化,表面积和投影面积。前背外侧身体区域和后背外侧身体区域均充当热窗。阴影下的numbats的太阳辐射热增益率较低,但非太阳辐射热增益的途径却很大。黑色条纹的辐射增益较高,白色条纹的辐射增益较低,但总的来说,条纹没有热作用。总热增益通常是正的(<4至>20W),并且常常大大超过代谢热产生(3-6W)。我们的热平衡模型表明,高环境热负荷限制了在空旷地区觅食10分钟,气候变化可能会延长不活动的时间,对未来的保护和管理有影响。我们得出的结论是,非侵入性热成像可为模拟自由生活的哺乳动物的热平衡提供信息。
    We used thermal imagining and heat balance modelling to examine the thermal ecology of wild mammals, using the diurnal marsupial numbat (Myrmecobius fasciatus) as a model. Body surface temperature was measured using infra-red thermography at environmental wet and dry bulb temperatures of 11.7-29°C and 16.4-49.3°C, respectively; surface temperature varied for different body parts and with environmental temperature. Radiative and convective heat exchange varied markedly with environmental conditions and for various body surfaces reflecting their shapes, surface areas and projected areas. Both the anterior and posterior dorsolateral body areas functioned as thermal windows. Numbats in the shade had lower rates of solar radiative heat gain but non-solar avenues for radiative heat gain were substantial. Radiative gain was higher for black and lower for white stripes, but overall, the stripes had no thermal role. Total heat gain was generally positive (<4 to >20 W) and often greatly exceeded metabolic heat production (3-6 W). Our heat balance model indicates that high environmental heat loads limit foraging in open areas to as little as 10 min and that climate change may extend periods of inactivity, with implications for future conservation and management. We conclude that non-invasive thermal imaging is informative for modelling heat balance of free-living mammals.
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  • 文章类型: Journal Article
    户外运动员经常避免使用防晒霜,因为他们认为防晒霜会损害体温调节的热量损失。过去研究防晒霜对体温调节的影响的研究是模棱两可的。这项研究的目的是确定矿物和化学防晒霜对干热(HD)和湿热(WH)环境中出汗反应和关键环境极限的影响。10名受试者(3M/7F;25±2年)接受了(1)无防晒霜(对照)的测试,(2)化学-,和(3)矿物基防晒霜。受试者暴露于进行性热应激,其中(1)在34°C下恒定干球温度(Tdb)并增加水蒸气压(Pa)(WH试验)或(2)在12mmHg下恒定Pa并增加Tdb(HD试验)。受试者以4.9±0.5METS行走,直到观察到胃肠道温度上升(即,关键环境限制)。与对照(39.9±3.0°C)相比,临界Tdb在矿物中没有差异(39.2±3.5°C,P=0.39)或化学(39.7±3.0°C,P=0.98)HD环境中的防晒试验。与对照组相比(18.8±4.0mmHg),临界Pa在矿物中没有差异(18.9±4.8mmHg,P=0.81)或化学(19.5±4.6mmHg,P=0.81)在WH环境中的防晒试验。出汗率,蒸发热损失,皮肤湿润,在WH(P=0.48)或HD(P=0.87)环境中,三项试验的出汗效率没有差异。关键的环境限制不受防晒霜应用的影响,表明防晒霜在高温运动期间不会改变综合的体温调节反应。
    Outdoor athletes often eschew using sunscreen due to perceived performance impairments, which many attribute in part to the potential for reduced thermoregulatory heat loss. Past studies examining the impact of sunscreen on thermoregulation are equivocal. The purpose of this study was to determine the effects of mineral and chemical-based sunscreens on sweating responses and critical environmental limits in hot-dry (HD) and warm-humid (WH) environments. Nine subjects (3 M/6 F; 25 ± 2 yr) were tested with 1) no sunscreen (control), 2) chemical-, and 3) mineral-based sunscreen. Subjects were exposed to progressive heat stress with either 1) constant dry-bulb temperature (Tdb) at 34°C and increasing water vapor pressure (Pa) (WH trials) or 2) constant Pa at 12 mmHg and increasing Tdb (HD trials). Subjects walked at 4.9 ± 0.5 metabolic equivalents (METs) until an upward inflection in gastrointestinal temperature was observed (i.e., the critical environmental limit). Compared with control (39.9 ± 3.0°C), critical Tdb was not different in mineral (39.2 ± 3.5°C, P = 0.39) or chemical (39.7 ± 3.0°C, P = 0.98) sunscreen trials in HD environments. Compared with control (18.8 ± 4.0 mmHg), critical Pa was not different in mineral (18.9 ± 4.8 mmHg, P = 0.81) or chemical (19.5 ± 4.6 mmHg, P = 0.81) sunscreen trials in WH environments. Sweating rates, evaporative heat loss, skin wettedness, and sweating efficiency were not different among the three trials in the WH (all P ≥ 0.48) or HD (all P ≥ 0.87) environments. Critical environmental limits are unaffected by sunscreen application, suggesting sunscreen does not alter integrative thermoregulatory responses during exercise in the heat.NEW & NOTEWORTHY Our findings demonstrate that neither sweating nor critical environmental limits were affected by mineral-based and chemical-based sunscreen applications. The rates of change in core temperature during compensable and uncompensable heat stress were not changed by wearing sunscreen. Evaporative heat loss, efficiency of sweat evaporation, skin wettedness, and sweating rates were unaffected by sunscreen. Sunscreen did not alter integrative thermoregulatory responses during exercise in the heat.
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  • 文章类型: Journal Article
    动物飞行以比任何其他运动方式更高的速率使用代谢能。相对较小比例的代谢能转化为机械动力;其余的作为热量释放。有效的散热对于避免热疗是必要的。在这项研究中,我们使用红外热成像技术测量了爱情鸟(Agapornispersonatus)的表面温度,并使用传热模型来计算对流散热,辐射和传导,之前,在飞行期间和之后。飞行鸟类的总非蒸发散热率比飞行前高12倍,比飞行后高19倍。在飞行中,热量大部分是通过强制对流消散的,通过暴露的腹侧机翼区域,与休息时的鸟类相比,表面温度较低。当栖息时,运动前后,头部和躯干是散热的主要区域。腿的表面温度随着飞行持续时间的增加而增加,并且在着陆时仍然很高,这表明在飞行过程中和飞行后流向该区域的温暖血液有所增加。在这项研究中开发的方法,以调查鸟类在飞行过程中如何调节温度,可以在未来的研究中使用,以评估气候变化对鸟类行为生态的影响。特别是那些进行迁徙飞行的物种。
    Animal flight uses metabolic energy at a higher rate than any other mode of locomotion. A relatively small proportion of the metabolic energy is converted into mechanical power; the remainder is given off as heat. Effective heat dissipation is necessary to avoid hyperthermia. In this study, we measured surface temperatures in lovebirds (Agapornis personatus) using infrared thermography and used heat transfer modelling to calculate heat dissipation by convection, radiation and conduction, before, during and after flight. The total non-evaporative rate of heat dissipation in flying birds was 12× higher than before flight and 19× higher than after flight. During flight, heat was largely dissipated by forced convection, via the exposed ventral wing areas, resulting in lower surface temperatures compared with birds at rest. When perched, both before and after exercise, the head and trunk were the main areas involved in dissipating heat. The surface temperature of the legs increased with flight duration and remained high on landing, suggesting that there was an increase in the flow of warmer blood to this region during and after flight. The methodology developed in this study to investigate how birds thermoregulate during flight could be used in future studies to assess the impact of climate change on the behavioural ecology of birds, particularly those species undertaking migratory flights.
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  • 文章类型: Journal Article
    传热系数(Kv)的测量是冷冻干燥机表征的重要组成部分,也是执行任何建模的必要步骤。在大多数情况下,仅计算Kv的平均值,或提供中心和边缘小瓶的平均值。我们的目标是更进一步,并描述各种小瓶/冷冻干燥器组合的整体Kv分布,无论压力如何。从实验的角度来看,在本文中,我们提出了三种基于冰升华重量法计算单个小瓶Kv值的方法。我们使用的第一种方法是最常见的方法,其中Kv值基于升华冰的质量和在选定的通孔中测量的产品温度来计算。在第二种方法中,估计每个小瓶的平均产品温度,基于升华前后的质量差,相应地计算Kv值。在第三种方法中,通过与来自模拟的升华结果进行比较来估计Kv。方法2和3的结果是非常相似的结果,并且与方法1的结果略有不同。方法1显示出系统偏差,因为它仅基于选定小瓶的记录温度,不能代表所有职位。一旦计算出Kv的各个值,可以为每种方法建立分布。观察到描述中心和边缘小瓶的两个正态分布的叠加提供了经验分布的良好表示。此外,我们提出了一个整体模型,旨在计算任何指定压力下的Kv分布。
    Measurement of heat transfer coefficients (Kv) is an important part of freeze-dryers characterization and as well a necessary step for executing any modelling. In most cases only an average value of Kv is calculated, or an average value of center and edge vials is provided. Our aim is to go a step further and to describe the overall Kv distribution various vial/ freeze drier combinations, whatever the pressure. From an experimental point of view, in this article we propose three methods to calculate the Kv value for individual vials based on the ice sublimation gravimetric method. The first method we use is the most usual one, where the Kv value is calculated based on the mass of sublimated ice and the product temperature measured in selected vias. In the second method, the average product temperature is estimated for each vial, based on the mass difference before and after sublimation and the Kv value is calculated accordingly. In the third method, the Kv is estimated by comparison to sublimation results from a simulation. Results from methods 2 and 3 are very similar results and are slightly different from those of method 1. Method 1 was shown to exhibit a systematic bias due to the fact that it is based on the temperature of recording of selected vials only, which are not representative for all positions. Once the individual values of Kv have been calculated, it is possible to establish a distribution for each method. It was observed that an overlay of two normal distributions describing the center and the edge vials provides a good representation of the empirical distribution. Furthermore, we propose a holistic model aiming to calculate the Kv distribution for any specified pressure.
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  • 文章类型: Journal Article
    管理温度是心脏骤停后护理的重要组成部分。在许多研究中,心脏骤停后的最初几天内发热或高热与较差的结果相关。临床数据尚未确定明显改善患者预后的任何目标温度或温度管理持续时间。当前的指南和最近的评论建议控制温度以防止热疗。较高的温度可以通过增加癫痫发作导致继发性脑损伤,脑水肿和代谢需求。一些数据表明,目标温度低于正常可能有利于选择这种病理常见的患者。临床温度管理应解决热平衡的生理学问题。核心温度反映了头部和躯干的热量,和核心温度的变化是由产热和热损失平衡的变化引起的。心脏骤停后患者的临床管理应包括在准确部位测量核心温度,并监测产热迹象,包括颤抖。多种方法可以增加或减少热损失,包括外部和内部设备。热量损失可以触发代偿反射,增加压力和代谢需求。因此,任何积极的温度管理应包括特定的药物治疗或其他干预措施,以控制产热,尤其是颤抖。需要更多的研究来确定个性化的温度管理是否可以改善结果。
    Managing temperature is an important part of post-cardiac arrest care. Fever or hyperthermia during the first few days after cardiac arrest is associated with worse outcomes in many studies. Clinical data have not determined any target temperature or duration of temperature management that clearly improves patient outcomes. Current guidelines and recent reviews recommend controlling temperature to prevent hyperthermia. Higher temperatures can lead to secondary brain injury by increasing seizures, brain edema and metabolic demand. Some data suggest that targeting temperature below normal could benefit select patients where this pathology is common. Clinical temperature management should address the physiology of heat balance. Core temperature reflects the heat content of the head and torso, and changes in core temperature result from changes in the balance of heat production and heat loss. Clinical management of patients after cardiac arrest should include measurement of core temperature at accurate sites and monitoring signs of heat production including shivering. Multiple methods can increase or decrease heat loss, including external and internal devices. Heat loss can trigger compensatory reflexes that increase stress and metabolic demand. Therefore, any active temperature management should include specific pharmacotherapy or other interventions to control thermogenesis, especially shivering. More research is required to determine whether individualized temperature management can improve outcomes.
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