目标:随着人口老龄化,血管外科医生正在逐渐变老,多患者存在围手术期并发症的风险。嵌入式医师已被证明可以改善普通和骨科手术的结果。本系统综述和荟萃分析旨在探讨外科医师共同管理模式对血管住院患者发病率和死亡率的影响。
方法:PubMed,Scopus,Embase,会议摘要列表,和临床试验注册。
方法:将接受联合管理的成人血管外科住院患者与“标准护理”进行比较的研究符合资格。死亡的相对风险(RR),医疗并发症,并计算了共同管理和标准护理之间30天的再入院时间。共同管理对平均住院时间的影响是使用加权方法计算的。使用非随机研究方法学指数评估偏倚风险,使用等级分析工具进行确定性评估。
结果:没有确定随机试验。纳入了2011年至2020年间的8项单一机构研究,共7410例患者。所有研究均采用前后方法进行观察。研究中存在高到中等偏倚风险,结果证据的等级确定性非常低。共同管理与统计学上显着降低的相对死亡率风险相关(RR0.64,95%置信区间[CI]0.44-0.92;p=.02),心脏并发症(RR0.47,95%CI0.25-0.87;p=0.02),血管性住院患者的感染性并发症(RR0.49,95%CI0.35-0.67;p<.001)。住院时间无统计学差异(MD-0.6天,95%CI-1.44-0.24天;p=.16)和30天再次入院(RR0.96,95%CI0.84-1.08;p=.49)。
结论:对于血管外科住院患者,医师和外科医生共同管理的早期结果从非常低的确定性数据中显示了有希望的结果。进一步精心设计,需要前瞻性研究来确定如何最大限度地发挥医生在血管服务中的影响,以改善患者的预后,同时有效地利用医院资源。
OBJECTIVE: As the population ages, vascular surgeons are treating progressively older, multimorbid patients at risk of peri-operative complications. An embedded physician has been shown to improve outcomes in general and orthopaedic surgery. This systematic review and meta-analysis aimed to investigate the impact of surgeon-physician co-management models on morbidity and mortality in vascular inpatients.
METHODS: PubMed, Scopus, Embase, conference abstract listings, and clinical trial registries.
METHODS: Studies comparing adult vascular surgery inpatients under co-management with \"standard of care\" were eligible. The relative risks (RRs) of mortality, medical complications, and 30 day re-admission between co-management and standard care were calculated. The effect of co-management on the mean length of stay was calculated using weighted means. Risk of bias was assessed using the Methodological Index for Non-Randomised Studies, and certainty assessment with the GRADE analysis tools.
RESULTS: No randomised trials were identified. Eight single institution studies between 2011 and 2020 with 7 410 patients were included. All studies were observational using before-after methodology. Studies were of high to moderate risk of bias, and outcomes were of very low GRADE certainty of evidence. Co-management was associated with a statistically significantly lower relative risk of mortality (RR 0.64, 95% confidence interval [CI] 0.44 - 0.92; p = .02), cardiac complications (RR 0.47, 95% CI 0.25 - 0.87; p = .02), and infective complications (RR 0.49, 95% CI 0.35 - 0.67; p < .001) in vascular inpatients. No statistically significant differences in length of stay (MD -0.6 days, 95% CI -1.44 - 0.24 days; p = .16) and 30 day re-admission (RR 0.96, 95% CI 0.84 - 1.08; p = .49) were noted.
CONCLUSIONS: Early results of physician and surgeon co-management for vascular surgery inpatients showed promising results from very low certainty data. Further well designed, prospective studies are needed to determine how to maximise the impact of physicians within a vascular service to improve patient outcomes while effectively using hospital resources.