head

Head
  • 文章类型: Journal Article
    通常在不同的条件下评估马的头部和骨盆垂直运动不对称性,但需要更好地了解这些不对称性如何因表面类型或圆形尺寸等因素而改变。这项研究调查了跨步持续时间,不同大小的圆圈中的表面和腹部运动影响了全面训练中骑马时客观测量的头部和骨盆运动不对称性。运动不对称性是用人体安装的加速度计记录的,并且是基于头部的两个垂直位移最小值或最大值之间的差异(HDmin,HDmax)和骨盆(PDmin,PDmax)在跨步周期内。每匹马在直线小跑和在硬表面和软表面上以缓慢和快速的速度(由跨步时间确定)进行训练(d=10m/15m)时进行评估。所有马(N=76)的至少一个运动不对称性参数高于预定义阈值(|HDmin|或|HDmax|>6mm,|PDmin|或|PDmax|>3mm)在硬表面(基线)上直线小跑期间。马匹被分配到一个“主要不对称”组(HDmin,HDmax,PDmin,PDmax)基于在基线条件下哪个运动不对称参数最大;将头部运动不对称值除以2以说明阈值大小的差异。使用线性混合模型-结果变量分别对每个主要不对称组进行分析:主要不对称参数;随机因素:马;固定因素:表面,以跨步持续时间为协变量的方向(P<0.05,Bonferroni事后校正)。\'方向\'条件是直线运动(\'直线\')或与直行条件的直行,进一步按圆直径以及按主要不对称分配的肢体(\'分配的肢体\')是否在圆的内侧或外侧(\'inside10\',\'inside15\',\'外部10\',\'outside15\')。仅与对侧肢体之间的不对称负重有关的参数(HDmin,PDmin)受到跨步持续时间变化的影响-最常见的模式是随着跨步持续时间的减少,不对称性增加。只有骨盆运动的不对称受到影响。当指定的后肢在圆的内侧时,与直线条件相比,PDmin不对称性增加,PDmax不对称性减少。指定的后肢在外面,PDmin不对称性降低,但PDmax不对称性没有改变。与15m圆相比,在10m圆上的微动并没有增加运动不对称性。总之,圆周运动和步幅的变化改变了在全骑工作中确定的马匹的运动不对称性,但在软表面和硬表面之间没有看到变化。这些模式应该在临床跛脚马中进一步研究。
    Head and pelvis vertical movement asymmetries in horses are often evaluated under different conditions yet better understanding is required of how these asymmetries are altered by factors such as surface type or circle size. This study investigated how stride duration, surface and lungeing in circles of different sizes influenced objectively measured head and pelvis movement asymmetries in riding horses in full training. Movement asymmetries were recorded with body mounted accelerometers and were based on the differences between the two vertical displacement minima or maxima of head (HDmin, HDmax) and pelvis (PDmin, PDmax) within a stride cycle. Each horse was evaluated during straight-line trot and during lungeing (d = 10m/15m) on hard and soft surfaces at slow and fast speed (determined by stride duration). All horses (N = 76) had at least one movement asymmetry parameter above a predefined thresholds (|HDmin| or |HDmax| >6mm, |PDmin| or |PDmax| >3mm) during a straight line trot on hard surface (baseline). The horses were assigned to a \'predominant asymmetry\' group (HDmin, HDmax, PDmin, PDmax) based on which movement asymmetry parameter was the greatest during the baseline condition; the head movement asymmetry values were divided by two to account for the difference in magnitude of the thresholds. Analysis was carried out for each predominant asymmetry group separately using linear mixed models-outcome variable: predominant asymmetry parameter; random factor: horse; fixed factors: surface, direction with stride duration as covariate (P<0.05, Bonferroni post-hoc correction). The \'direction\' conditions were either a straight-line locomotion (\'straight\') or lungeing with lungeing conditions further classified by circle diameter and by whether the limb which the predominant asymmetry was assigned to (\'assigned limb\') was on the inside or outside of the circle (\'inside10\', \'inside15\', \'outside10\', \'outside15\'). Only parameters related to asymmetrical weight-bearing between contralateral limbs (HDmin, PDmin) were affected by changes in stride duration-the most common pattern was an increase in asymmetries as stride duration decreased. Only pelvic movement asymmetries were affected by lungeing. When the assigned hindlimb was on the inside of the circle, the PDmin asymmetries increased and PDmax asymmetries decreased compared to the straight-line condition. With the assigned hindlimb on the outside, PDmin asymmetries decreased but PDmax asymmetries did not change. Trotting on 10 m circle compared to 15 m circle did not increase movement asymmetries. In conclusion, circular motion and changes in stride duration altered movement asymmetries identified in horses in full ridden work but no changes were seen between the soft and hard surfaces. These patterns should be further investigated in clinically lame horses.
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  • 文章类型: Journal Article
    我们首先根据性别和月龄建立海南省婴儿身长和头围百分位参考曲线,并与2022年国家标准和世界卫生组织(WHO)标准进行比较。这项横断面调查涉及海南省18个市县的2736名婴儿(1471名男孩和1265名女孩)。使用标准化仪器测量头围和长度。使用LMS方法确定海南婴儿身长和头围的参考值。使用LMS图表制作软件生成曲线。根据新建立的参考曲线,海南婴幼儿身长和头围呈稳定增长趋势。然而,平均头围低于2022年国家参考值和世卫组织标准.平均长度低于新的国家参考值,但大致符合WHO标准。与全国和全球平均水平相比,海南的婴儿身长和头围存在差异。为了提高婴儿的身长和头围增长,卫生部门应鼓励头6个月纯母乳喂养,确保婴儿晚上的睡眠需求,促进围产期补充维生素D的规律性。
    We first established percentile reference curves for infant length and head circumference in Hainan Province based on gender and age in months and compared them with the 2022 national standards and World Health Organization (WHO) standards. This cross-sectional survey involved 2736 infants (1471 boys and 1265 girls) in 18 cities and counties in Hainan Province. Standardized instruments were used to measure head circumference and length. Reference values for Hainan infants\' length and head circumference were determined using the LMS method. Curves were generated using the LMS Chart Maker software. According to the newly established reference curves, the length and head circumference of Hainan infants exhibited a consistent trend of steady growth. However, the average head circumference was below the 2022 national reference values and WHO standards. The mean length was lower than the new national reference values but roughly consistent with the WHO standards. Differences exist in infant length and head circumference in Hainan compared to national and global averages. To enhance infant length and head circumference growth, the health department should encourage exclusive breastfeeding for the first 6 months, ensure infants\' sleep needs at night, and promote the regularity of vitamin D supplementation during the perinatal period.
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  • 文章类型: Journal Article
    为了帮助放射科医生检查越来越多的计算机断层扫描(CT)扫描,自动异常检测是医学影像研究的热点。放射科医生必须通过搜索与正常健康解剖结构的任何偏差来分析CT扫描。我们提出了一种检测大脑轴向2DCT切片图像异常的方法。尽管已经进行了许多关于检测大脑磁共振图像异常的研究,CT扫描的工作很少,由于必须由所使用的模型表示的图像对比度低,因此更难以检测到异常。
    我们在第一步中使用生成对抗网络(GAN)来学习正常的大脑解剖结构,并比较两种图像重建方法:在第二步中训练编码器,并在推理过程中使用迭代优化。然后,我们分析与原始扫描的差异,以检测和定位大脑中的异常。
    我们的方法可以重建具有良好图像对比度的健康解剖结构,用于脑部CT扫描。我们在出血测试数据上获得的中位Dice评分为0.71,在测试集上获得的中位Dice评分为0.43,其他肿瘤图像来自公开可用的数据源。我们还将我们的模型与最先进的自动编码器和扩散模型进行比较,并获得定性更准确的重建。
    在训练期间没有定义异常,我们使用基于GAN的网络来学习用于脑部CT扫描的健康解剖学.值得注意的是,我们的方法不仅限于出血和肿瘤的定位,因此可用于检测结构解剖变化和其他病变.
    UNASSIGNED: To help radiologists examine the growing number of computed tomography (CT) scans, automatic anomaly detection is an ongoing focus of medical imaging research. Radiologists must analyze a CT scan by searching for any deviation from normal healthy anatomy. We propose an approach to detecting abnormalities in axial 2D CT slice images of the brain. Although much research has been done on detecting abnormalities in magnetic resonance images of the brain, there is little work on CT scans, where abnormalities are more difficult to detect due to the low image contrast that must be represented by the model used.
    UNASSIGNED: We use a generative adversarial network (GAN) to learn normal brain anatomy in the first step and compare two approaches to image reconstruction: training an encoder in the second step and using iterative optimization during inference. Then, we analyze the differences from the original scan to detect and localize anomalies in the brain.
    UNASSIGNED: Our approach can reconstruct healthy anatomy with good image contrast for brain CT scans. We obtain median Dice scores of 0.71 on our hemorrhage test data and 0.43 on our test set with additional tumor images from publicly available data sources. We also compare our models to a state-of-the-art autoencoder and a diffusion model and obtain qualitatively more accurate reconstructions.
    UNASSIGNED: Without defining anomalies during training, a GAN-based network was used to learn healthy anatomy for brain CT scans. Notably, our approach is not limited to the localization of hemorrhages and tumors and could thus be used to detect structural anatomical changes and other lesions.
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  • 文章类型: Journal Article
    与运动相关的脑震荡是由对头部或身体的一次重大撞击或几次较小的撞击导致头部加速引起的,导致大脑颤抖。有运动相关脑震荡病史的运动员在着陆任务中表现出下肢生物力学,这有助于增加受伤风险。然而,着陆任务中头部加速度对下肢生物力学的影响尚不清楚.将20名参与者均匀分为垂直跳跃组和横向跳跃组。参与者在跳跃干预前后进行了几次土地和切割操作。在跳跃干预期间通过加速度计测量垂直头部加速度(g)。组间比较了跳跃任务期间的头部加速度。此外,比较了组内干预前后以及组间干预后的运动学和动力学变量.与横向跳跃组相比,垂直跳跃组显示出更大的垂直头部加速度(p=0.04)。此外,与横向跳跃组相比,垂直跳跃组干预后着陆时膝关节外展角度更大(p<0.000).在着陆任务期间,通过连续跳跃引起头部加速度会影响下肢生物力学。
    Sports-related concussions are caused by one substantial impact or several smaller-magnitude impacts to the head or body that lead to an acceleration of the head, causing shaking of the brain. Athletes with a history of sports-related concussion demonstrate lower-extremity biomechanics during landing tasks that are conducive to elevated injury risk. However, the effect of head acceleration on lower-extremity biomechanics during landing tasks is unknown. Twenty participants were evenly separated into a vertical hopping group and a lateral hopping group. Participants performed several land-and-cut maneuvers before and after a hopping intervention. Vertical head acceleration (g) was measured via an accelerometer during the hopping interventions. Comparisons in head acceleration during the hopping tasks were made between groups. Additionally, kinematic and kinetic variables were compared pre- and post-intervention within groups as well as post-intervention between groups. The vertical hopping group demonstrated greater vertical head acceleration compared to the lateral hopping group (p = 0.04). Additionally, the vertical hopping group demonstrated greater knee abduction angles during landing post-intervention compared to the lateral hopping group (p < 0.000). Inducing head acceleration via continuous hopping had an influence on lower-extremity biomechanics during a landing task.
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  • 文章类型: Journal Article
    不对称研究可以表明发育过程中的干扰。波动不对称性(FA)被认为是压力的指标。Sanmartinero(SM)克里奥尔牛原产于Meta部门(哥伦比亚Orinoquia),其适应过程使其能够生活在极端的热带环境中。这项横断面和描述性研究的目的是介绍SM克里奥尔牛某些头部特征的不对称性知识的现状。共研究了来自三个不同农场的94只动物(18只未阉割的雄性和76只雌性),年龄范围为0.5-10岁。对于每一种动物,在体内获得耳朵的两个测量值(宽度和长度)和角的两个测量值(周长和长度)。不对称程度计算为(R-L)/(R+L)。双边差异指向波动的不对称性(例如,预期完全对称的特征的随机变化)偏向右耳宽度和角周长,和向左的耳朵和角的长度。因为这些结构——耳朵和角——的发展是在同一组基因的控制下,波动的不对称性可能构成正常状况的反映。
    Asymmetric studies can indicate disturbances in the developmental process. Fluctuating asymmetry (FA) is considered an indicator of stress. The Sanmartinero (SM) creole bovine is native to the department of Meta (Colombian Orinoquia) and its adaptation process has allowed it to live in extreme tropical environments. The aim of this cross-sectional and descriptive study was to present the current state of the knowledge of asymmetries in some cephalic characters of the SM creole bovine. A total of 94 animals were studied (18 uncastrated males and 76 females) from three different farms, with an age range of 0.5-10 years. For each animal, two measurements of the ear (width and length) and two measurements of the horn (perimeter and length) were obtained in vivo. The degree of asymmetry was calculated as (R - L)/(R + L). Bilateral differences pointed towards a fluctuating asymmetry (e.g., a random variation in the trait that is expected to be perfectly symmetrical) biased towards right for ear width and horn perimeter, and towards left for ear and horn length. Since the development of these structures-ears and horns-is under the control of the same set of genes, the fluctuating asymmetry could constitute a reflection of a normal condition.
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  • 文章类型: English Abstract
    Objective:To explore the clinical characteristics of sarcoidosis of head and neck symptoms, and to summarize the diagnosis and treatment experience. Methods:A retrospective study was conducted on patients with nodular disease with main symptoms in the head and neck who visited Henan Provincial People\'s Hospital from January 2020 to August 2023. The clinical data including symptom characteristics, pathological characteristics, treatment methods, and prognosis were analyzed. Results:A total of 14 patients were included, with 4 males(28.6%) and 10 females(71.4%), age ranged from 11 to 71 years, with an average age of(52.0±15.8) years. The lesions were located in the parotid gland in 2 cases and the neck in 12 cases. Twelve cases underwent neck mass resection surgery, and 2 cases underwent ultrasound-guided core biopsy of parotid gland tumor and postoperative pathological diagnosis was confirmed in all cases. Four cases received steroid treatment postoperatively, and showed good prognosis with reduced lesion size after 3 months. Three cases did not take medication and the lesions continued to persist, causing discomfort. Seven cases did not take medication postoperatively, and the lesions expanded with multi-organ progression. Conclusion:Patients with head and neck sarcoidosis are rare in clinical practice, and it is prone to misdiagnosis and missed diagnosis. Steroid therapy can achieve good therapeutic effects.
    目的:探讨以头颈部症状为主的结节病的临床特点,并总结其诊治经验。 方法:回顾性纳入2020年1月-2023年8月于河南省人民医院就诊的以头颈部症状为主的结节病患者,分析其症状特点、病理学特征、治疗方式及预后情况等临床资料。 结果:共纳入14例患者,其中男4例(28.6%),女10例(71.4%);年龄11~71岁,平均(52.0±15.8)岁。病变位于腮腺2例,颈部12例。12例行颈部肿物切除术,2例行超声引导下腮腺肿物粗针穿刺术,术后均经病理明确诊断。4例术后辅以激素治疗,术后3个月预后良好,病变范围缩小;3例未服用药物,病变持续存在,仍感不适;7例术后未服用药物,病变范围扩大,多器官进展。 结论:头颈部结节病的患者临床少见,容易漏诊、误诊,选用激素治疗可获得良好疗效。.
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  • 文章类型: English Abstract
    Objective:To establish the normal values of subjective visual vertical (SVV) in different head deflection angles and analyze its test and retest reliability, in order to provide a reference for the clinical application of SVV in the evaluation of vestibular disorders. Methods:Thirty-one healthy young people were selected to wear VR glasses, and the SVV data were tested in five different head-tilt, namely, 0° in the upright head position, 45°in the left head position, 45° in the right head position, 90° in the left head position, and 90° in the right head position, and were re-tested 2 weeks later. Results:①The mean values of SVV at 5 different head-tilt angles of 0°, left 45°, right 45°, left 90°, and right 90° were -0.07±1.71, 4.30±5.39, -6.51±5.58, -3.76±7.42, and 0.40±8.02, respectively, The 95% confidence limits of SVV at 0°, left 45°, right 45°, left 90°, right 90°, and right 90° were (-3.42, 3.28), (-6.26, 14.86), (-17.45, 4.43), (-18.30, 10.78), and(-15.32, 16.12), respectively; ②The absolute values of SVV at 4 different head-tilt angles of left 45°, right 45°, left 90°, and right 90° were 5.62±3.96, 6.90±5.07, 6.82±4.70 and 6.48±4.68, respectively. The 95% confidence limits of SVV at left 45°, right 45°, left 90°, right 90°, and right 90° were(0,12.11),(0,15.21),(0,14.53)and(0,14.16), respectively. The asymmetry ratio is 10% for the absolute value of the 45 ° deviation and 3% for the absolute value of the 90° deviation; ③Intra-class correlation coefficients(ICC) for 0°, left 45°, right 45°, left 90°, right 90°were 0.757, 0.673, 0.674, 0.815, and 0.856, respectively. Conclusion:SVV has good retest reliability and high stability, and the SVV normal value data of different head deviation angles established in the present study can be used as a reference for the diagnosis and evaluation of vestibular disorders.
    目的:建立不同头位偏斜角度下的主观视觉垂直线(subjective visual vertical,SVV)正常值数据,并分析其复测信度,为SVV的临床应用提供参考。 方法:选取31名健康青年人,佩戴虚拟现实眼镜,分别测试在直立头位0°、左头位偏斜45°(L45°)、右头位偏斜45°(R45°)、左头位偏斜90°(L90°)、右头位偏斜90°(R90°)5个不同角度下的SVV数据,并于2周后进行复测。 结果:①0°、L45°、R45°、L90°、R90° 5个不同头位偏斜角度下的SVV平均值分别为:-0.07±1.71、4.30±5.39、-6.51±5.58、-3.76±7.42、0.40±8.02,95%CI分别为:(-3.42,3.28)、(-6.26,14.86)、(-17.45,4.43)、(-18.30,10.78)、(-15.32,16.12);②L45°、R45°、L90°、R90°4个不同头位偏斜角度下的SVV偏差绝对值分别为:5.62±3.96、6.90±5.07、6.82±4.70、6.48±4.68;95%CI分别为:(0,12.11)、(0,15.21)、(0,14.53)、(0,14.16);双侧45°偏差绝对值的不对称性比为10%;双侧90°偏差绝对值的不对称性比为3%;③0°、L45°、R45°、L90°、R90° SVV的组内相关系数分别为0.757、0.673、0.674、0.815、0.856。 结论:SVV具有良好的复测信度,临床测试稳定性高,本研究建立的不同偏斜角度下SVV正常值数据可辅助临床对前庭系统疾病进行精细化诊断和功能评估。.
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  • 文章类型: Journal Article
    目的:本研究旨在评估和比较汽车和自行车驾驶员前头姿势(FHP)的患病率,及其与颈部和心肺参数的潜在相关性。
    方法:这项横断面研究涉及来自勒克瑙市区和郊区的400名参与者,北方邦,印度,包括200名汽车司机和200名年龄在18-65岁之间、至少有五年驾驶历史的自行车司机。使用诸如颈椎活动范围和颈部残疾指数(NDI)之类的测量来评估颈部健康。通过静息心率评估心肺参数,血压,和使用肺活量测定测试的肺功能测试,和FHP使用Surgimap应用程序进行评估。使用IBMSPSSStatistics软件(26.0版)进行统计分析,包括描述性统计,假设检验,二进制数据的卡方检验或Fisher精确检验,和相关分析。
    结果:结果表明,汽车和自行车驾驶员的平均FHP差异具有统计学意义(p=0.0001),表明汽车司机的FHP患病率高于自行车司机。相关分析显示FHP和颈部健康指标之间存在显著关联,尤其是颈椎屈曲(r=0.71,p<0.05),(r=0.78,p<0.05)和左侧旋转(r=0.56,p<0.05),(r=0.61,p<0.05)在汽车和自行车驾驶员中。在心肺参数中,静息心率与FHP显著相关(r=0.33,p<0.05),(r=0.42,p<0.05),肺活量测定结果FVC(r=0.29,p<0.05),FEV1(r=0.22,p<0.05),汽车和自行车驾驶员的FVC(r=0.31,p<0.05)。
    结论:我们观察到汽车驾驶员的FHP发生率更高,表明在骑自行车的过程中,长时间的静态姿势可能比动态移动导致更大的姿势偏差。这种关联表明,FHP可能对全身健康产生广泛的影响,超越肌肉骨骼问题。这些发现有可能影响旨在改善驾驶员整体健康结果的预防策略和干预措施。
    OBJECTIVE: This study aimed to evaluate and compare the prevalence of Forward Head Posture (FHP) in car and bike drivers, and its potential correlation with neck and cardiopulmonary parameters.
    METHODS: This cross-sectional study involved 400 participants from urban and suburban areas around Lucknow, Uttar Pradesh, India, including 200 car drivers and 200 bike drivers aged 18-65 years with a minimum five-year driving history. Neck health was assessed using measurements such as cervical range of motion and Neck Disability Index (NDI), cardiopulmonary parameters were evaluated through resting heart rate, blood pressure, and pulmonary function tests using the spirometry test, and FHP was assessed using Surgimap application. Statistical analysis was performed using IBM SPSS Statistics software (version 26.0) and included descriptive statistics, hypothesis testing, Chi-square or Fisher\'s exact test for binary data, and correlation analyses.
    RESULTS: The result show that difference in the mean FHP between car and bike drivers was statistically significant (p = 0.0001), indicating a higher prevalence of FHP among car drivers than among bike drivers. Correlation analyses revealed significant associations between FHP and neck health metrics, especially cervical flexion (r = 0.71, p<0.05), (r = 0.78, p<0.05) and left-side rotation (r = 0.56, p<0.05), (r = 0.61, p<0.05) in car and bike drivers. Among the cardiopulmonary parameters, significant correlations with FHP were observed in resting heart rate (r = 0.33, p<0.05), (r = 0.42, p<0.05), spirometry results FVC (r = 0.29, p<0.05), FEV1 (r = 0.22, p<0.05), and FVC (r = 0.31, p<0.05) for car and bike drivers.
    CONCLUSIONS: We observed a higher incidence of FHP in car drivers, indicating that a prolonged static posture may lead to greater postural deviation than dynamic movement during biking. This association suggests that FHP could have wide-reaching implications for systemic health, beyond musculoskeletal issues. These findings have the potential to influence preventative strategies and interventions aimed at improving the overall health outcomes for drivers.
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  • 文章类型: Journal Article
    解剖学损害了对活蛇的体长和头部大小进行测量的精度和准确性。身体措施(鼻孔长度,SVL)包含许多滑膜椎间关节,每个允许弯曲和有限的伸展和压缩。在静息和拉伸条件下,14种系统发育多样性物种的躯干的放射学图以及对椎间关节的解剖和组织学分析表明,这些关节的滑膜性质是SVL测量差异的基础。同样,连接阿尔西诺皮人蛇的可移动鼻子和下颌元素的粘弹性组织的普遍存在和多样性是头部长度和宽度测量差异的基础。对于头部和钳口装置的整体尺寸,对于许多蛇来说,最容易和相对精确地测量的部分是下颌骨,因为它只有一个活动关节。至于准确性,椎间和颅骨关节的解剖结构支持这样的假设,即在活蛇中,头部和躯干没有确切的尺寸。
    Anatomy compromises the precision and accuracy of measurements made of the body length and head size of live snakes. Body measures (snout-vent length, SVL) incorporate many synovial intervertebral joints, each allowing flexion and limited extension and compression. Radiographs of the trunk in 14 phylogenetically diverse species in resting and stretched conditions combined with dissections and histological analysis of intervertebral joints show that the synovial nature of these joints underlies the variance in SVL measures. Similarly, the ubiquity and variety of viscoelastic tissues connecting mobile snout and jaw elements of alethinophidian snakes underlie variances in length and width measures of the head. For the overall size of the head and jaw apparatus, the part that can be most easily and relatively precisely measured for many snakes is the mandible because it has only one mobile joint. As to accuracy, the anatomy of intervertebral and cranial joints supports the hypothesis that in living snakes, the head and trunk have no exact size.
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  • 文章类型: Journal Article
    目的:脑出血(ICH)中血肿扩大(HE)是影响患者预后的关键因素,然而,目前缺乏预测HE的有效临床工具。我们的目标是开发一个基于深度学习的全自动框架,用于仅使用临床非对比CT(NCCT)扫描来预测HE。
    方法:从84个中心收集了一个大型回顾性数据集(n=2484),而前瞻性数据集(n=500)来自26个其他中心。基线NCCT扫描和随访NCCT扫描在6小时和48小时内从症状发作,分别。HE定义为随访NCCT时体积增加超过6mL。根据患者纳入时间将回顾性数据集分为训练集(n=1876)和验证集(n=608)。训练了一个两阶段框架来预测HE,并在验证集和预期集上评估了其性能。接收机工作特性曲线下面积(AUC),灵敏度,和特异性被利用。
    结果:我们的两阶段框架在回顾性验证集上的AUC为0.760(95%CI0.724-0.799),在前瞻性集上的AUC为0.806(95%CI0.750-0.859),优于常用的BAT得分,其AUC分别为0.582和0.699。
    结论:我们的框架可以使用入院头颅NCCT扫描自动且稳健地识别处于HE高风险的ICH患者,提供比BAT分数更准确的预测。
    OBJECTIVE: Hematoma expansion (HE) in intracerebral hemorrhage (ICH) is a critical factor affecting patient outcomes, yet effective clinical tools for predicting HE are currently lacking. We aim to develop a fully automated framework based on deep learning for predicting HE using only clinical non-contrast CT (NCCT) scans.
    METHODS: A large retrospective dataset (n = 2484) was collected from 84 centers, while a prospective dataset (n = 500) was obtained from 26 additional centers. Baseline NCCT scans and follow-up NCCT scans were conducted within 6 h and 48 h from symptom onset, respectively. HE was defined as a volume increase of more than 6 mL on the follow-up NCCT. The retrospective dataset was divided into a training set (n = 1876) and a validation set (n = 608) by patient inclusion time. A two-stage framework was trained to predict HE, and its performance was evaluated on both the validation and prospective sets. Receiver operating characteristics area under the curve (AUC), sensitivity, and specificity were leveraged.
    RESULTS: Our two-stage framework achieved an AUC of 0.760 (95% CI 0.724-0.799) on the retrospective validation set and 0.806 (95% CI 0.750-0.859) on the prospective set, outperforming the commonly used BAT score, which had AUCs of 0.582 and 0.699, respectively.
    CONCLUSIONS: Our framework can automatically and robustly identify ICH patients at high risk of HE using admission head NCCT scans, providing more accurate predictions than the BAT score.
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