肠相关淋巴组织（GALT）癌，也被称为圆顶型癌症，是结直肠腺癌的一种罕见的独特亚型，在英国医学文献中仅报道了18例。这些肿瘤具有独特的临床病理特征，被认为具有低恶性潜能，预后良好。在这里，我们描述了一例49岁男性间歇性便血2年的病例.结肠镜检查显示乙状结肠距肛门260mm处有约20mm×17mm的无蒂宽基息肉，表面有轻微充血。组织学上,该病变显示典型的GALT癌。患者随访一年半，没有出现任何不适，如腹痛或便血，无肿瘤复发。此外，我们回顾了文献，总结了GALT癌的临床病理特征，并强调了其病理鉴别诊断，以进一步探讨这种罕见的结直肠腺癌类型。
Gut-associated lymphoid tissue (GALT) carcinoma, also termed dome-type carcinoma, is an infrequent distinctive subtype of colorectal adenocarcinoma and only 18 cases have been reported in the English medical literature. These tumors have unique clinicopathological features and are considered to have a low malignant potential with favorable prognosis. Herein, we described a case of a 49-year-old male with intermittent hematochezia for 2 years. Colonoscopy revealed a sessile broad-based polyp of approximately 20 mm × 17 mm in the sigmoid colon 260 mm away from the anus, with a slightly hyperemic surface. Histologically, this lesion showed typical GALT carcinoma. The patient was followed up for one and a half year and he did not experience any discomfort, such as abdominal pain or hematochezia, and no tumor recurrence occurred. Moreover, we reviewed the literature, summarized the clinicopathological features of GALT carcinoma, and highlighted its pathological differential diagnosis to further explore this infrequent type of colorectal adenocarcinoma.
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