goals

目标
  • 文章类型: Journal Article
    背景:健康人倡议是一项全国性的努力,旨在每十年在美国制定公共卫生目标。在其最新的迭代中,2030年健康人,与避孕相关的关键目标侧重于在有意外怀孕风险的妇女中增加使用有效的节育(被归类为对预防怀孕最有效或中等有效的避孕方法)。这种狭隘的关注与性健康和生殖健康平等不一致,认识到个人自我定义的避孕药具需求对于监测避孕药具的获取以及设计政策和方案战略以增加获取至关重要。
    目的:我们旨在比较2种人口水平的避孕药具获取指标:常规指标,在被认为有意外怀孕风险的人群中,使用被认为对预防怀孕最有效或中等有效的避孕方法(接近健康人群2030方法),和以人为中心的度量标准,在当前和未来的避孕使用者中使用首选的避孕方法。
    方法:我们使用2022年收集的具有全国代表性的数据来构建避孕药具获取的2个指标;总体样本包括出生时没有使用女性绝育或以其他方式感染并且没有怀孕或试图怀孕的女性(未加权N=2760;人口估计:4390万)。我们进行了比较分析,通过检查个人是否满足两个指标的分母的纳入标准,来检查指标的趋同和背离,都不是度量,只有传统的度量标准,或仅以人为中心的指标。
    结果:比较两种方法来测量避孕方法,我们发现,79%的受访者被纳入或排除在这两个指标之外(反映出,当个体被两个指标同等对待时,这些指标趋同).其余21%代表指标的差异,估计有570万不想使用避孕方法的个体仅包括在常规公分母中,估计有350万正在使用或想使用避孕方法但从未将阴茎阴道性交仅包括在以人为中心的公分母中。在仅包含在常规度量中的那些中,100%是不使用避孕药的非使用者,他们也不想。在仅包括在以人为中心的度量中的那些中,目前有68%的人使用避孕方法。尽管他们目前或希望使用避孕药具,这些人被排除在常规指标之外,因为他们从未有过阴茎-阴道性行为.
    结论:我们的分析强调,经常使用的避孕药具获取指标错过了数百万人的需求,同时包括了非使用者的内容,并排除了那些正在使用或想要使用从未发生过性行为的避孕药具的人。记录和量化当前评估避孕方法与更多以人为中心的方法之间的差距,有助于清楚地确定方案和政策努力应集中在哪里。
    BACKGROUND: The Healthy People initiative is a national effort to lay out public health goals in the United States every decade. In its latest iteration, Healthy People 2030, key goals related to contraception focus on increasing the use of effective birth control (contraceptive methods classified as most or moderately effective for pregnancy prevention) among women at risk of unintended pregnancy. This narrow focus is misaligned with sexual and reproductive health equity, which recognizes that individuals\' self-defined contraceptive needs are critical for monitoring contraceptive access and designing policy and programmatic strategies to increase access.
    OBJECTIVE: We aimed to compare 2 population-level metrics of contraceptive access: a conventional metric, use of contraceptive methods considered most or moderately effective for pregnancy prevention among those considered at risk of unintended pregnancy (approximating the Healthy People 2030 approach), and a person-centered metric, use of preferred contraceptive method among current and prospective contraceptive users.
    METHODS: We used nationally representative data collected in 2022 to construct the 2 metrics of contraceptive access; the overall sample included individuals assigned female at birth not using female sterilization or otherwise infecund and who were not pregnant or trying to become pregnant (unweighted N=2760; population estimate: 43.9 million). We conducted a comparative analysis to examine the convergence and divergence of the metrics by examining whether individuals met the inclusion criteria for the denominators of both metrics, neither metric, only the conventional metric, or only the person-centered metric.
    RESULTS: Comparing the 2 approaches to measuring contraceptive access, we found that 79% of respondents were either included in or excluded from both metrics (reflecting that the metrics converged when individuals were treated the same by both). The remaining 21% represented divergence in the metrics, with an estimated 5.7 million individuals who did not want to use contraception included only in the conventional metric denominator and an estimated 3.5 million individuals who were using or wanted to use contraception but had never had penile-vaginal sex included only in the person-centered metric denominator. Among those included only in the conventional metric, 100% were content nonusers-individuals who were not using contraception, nor did they want to. Among those included only in the person-centered metric, 68% were currently using contraception. Despite their current or desired contraceptive use, these individuals were excluded from the conventional metric because they had never had penile-vaginal sex.
    CONCLUSIONS: Our analysis highlights that a frequently used metric of contraceptive access misses the needs of millions of people by simultaneously including content nonusers and excluding those who are using or want to use contraception who have never had sex. Documenting and quantifying the gap between current approaches to assessing contraceptive access and more person-centered ones helps clearly identify where programmatic and policy efforts should focus going forward.
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  • 文章类型: Journal Article
    背景需要更多的研究来了解在基于能力的临床学习环境中实施结构化目标设定对受训者参与的影响。目的探讨2家医院老年医学轮换中居民如何进行轮换针对性目标设定干预。方法期望所有轮换居民完成干预,由基于SMART的(具体而言,可测量,可成就,相关,和限时)目标设定表格和与教学人员的反馈会议。从2019年11月到2021年6月,我们招募了轮换居民的便利样本。研究参与者完成了轮换前后35项荷兰居民教育气候测试(D-RECT)问卷,以比较他们在老年轮换和轮换后半结构化访谈之前的轮换得分,我们使用不断比较和反身主题分析的原理对其进行转录和分析。结果我们采访了参与目标设定干预的58名居民中的12名(20.7%),其中11人完成了两份D-RECT问卷。与前一次临床轮换相比,参与者的D-RECT评分更有利于老年医学轮换(M=4.29±0.37;M=3.84±0.44,P=.002)。访谈记录的分析产生了3个主题,关于参与者如何感知干预影响他们的学习经验:(1)结构化的形式和过程调解,通知,并限制目标选择;(2)与教师的互动,病人,和系统因素影响目标制定;(3)非结构化评估导致目标实现的不确定性。挑战包括时间限制和不可预测的临床机会。结论目标设定似乎可以帮助许多居民指导他们的学习努力,并与教职员工参与协作过程。我们确定了限制居民参与目标设定干预的挑战,这可以为其他基于能力的课程中目标设定的实际实施提供信息。
    Background More research is required to understand the effects of implementing structured goal-setting on trainee engagement in competency-based clinical learning environments. Objective To explore how residents experienced a rotation-specific goal-setting intervention on geriatric medicine rotations at 2 hospitals. Methods All rotating residents were expected to complete the intervention, consisting of a SMART-based (Specific, Measurable, Achievable, Relevant, and Time-Bound) goal-setting form and feedback sessions with teaching faculty. From November 2019 to June 2021, we recruited a convenience sample of rotating residents. Study participants completed pre- and postrotation 35-item Dutch Residency Educational Climate Test (D-RECT) questionnaires to compare scores from their rotation before the geriatric rotation and a postrotation semistructured interview, which we transcribed and analyzed using principles of constant comparison and reflexive thematic analysis. Results We interviewed 12 of 58 (20.7%) residents participating in the goal-setting intervention, 11 of whom completed both D-RECT questionnaires. Participants\' D-RECT scores favored the geriatric medicine rotation versus the immediately preceding clinical rotation (M=4.29±0.37; M=3.84±0.44, P=.002). Analyses of interview transcripts yielded 3 themes on how participants perceived the intervention influenced their learning experience: (1) structured forms and processes mediate, inform, and constrain goal selection; (2) interactions with faculty, patients, and system factors influenced goal enactment; and (3) unstructured assessments led to uncertainty around goal achievement. Challenges included time restrictions and unpredictable clinical opportunities. Conclusions Goal-setting appeared to help many residents direct their learning efforts and engage in collaborative processes with teaching faculty. We identified challenges limiting residents\' engagement with the goal-setting intervention, which may inform the practical implementation of goal-setting in other competency-based curricula.
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  • 文章类型: Journal Article
    背景:严格的安全性(CVS)对于确保安全的腹腔镜胆囊切除术很重要。当CVS是不可能的,进行胆囊次全切除术.在考虑胆囊次全切除术时,外科医生通常关心的是防止胆囊管的胆漏。急性胆囊炎的胆囊次全切除术的两种主要类型是开窗和重建。以前,这两个没有选择标准;因此,进行开放转换。这项研究旨在评估我们以目标为导向的方法,以选择开窗或重建急性胆囊炎的胆囊次全切除术。
    方法:我们在2019年4月推出了面向目标的方法。在介绍这种方法之前,急性胆囊炎的腹腔镜胆囊切除术无胆囊次全切除术标准。我们的方法引入后,根据大部胆囊切除术标准对急性胆囊炎进行腹腔镜胆囊切除术。我们回顾性回顾了2015年至2021年间因急性胆囊炎而接受腹腔镜胆囊切除术的患者的病历。腹腔镜胆囊切除术治疗急性胆囊炎由外科医生进行,无论他们是新手还是退伍军人。
    结果:从2015年4月到2019年3月的时期是在我们的方法引入(BI)之前,从2019年4月到2021年12月的时期是在我们的方法引入(AI)之后。在BI和AI期间有177和186例急性胆囊炎患者,分别。两组在术前特征方面无显著差异,手术时间,和失血。组间腹腔镜胆囊次全切除率无差异(10.2%[BI]vs.[AI]13.9%;p=0.266)。BI期间的开放转化率明显高于AI期间(7.4%vs.1.6%;p=0.015)。
    结论:我们的目标导向方法是可行的,安全,许多外科医生容易理解。
    BACKGROUND: A critical view of safety (CVS) is important to ensure safe laparoscopic cholecystectomy. When the CVS is not possible, subtotal cholecystectomy is performed. While considering subtotal cholecystectomy, surgeons are often concerned about preventing bile leakage from the cystic ducts. The two main types of subtotal cholecystectomy for acute cholecystitis are fenestrating and reconstituting. Previously, there were no selection criteria for these two; therefore, open conversion was performed. This study aimed to evaluate our goal-oriented approach to choose fenestrating or reconstituting subtotal cholecystectomy for acute cholecystitis.
    METHODS: We introduced our goal-oriented approach in April 2019. Before introducing this approach, laparoscopic cholecystectomy for acute cholecystitis was performed without criteria for subtotal cholecystectomy. After our approach was introduced, laparoscopic cholecystectomy for acute cholecystitis was performed according to the subtotal cholecystectomy criteria. We retrospectively reviewed the medical records of patients who underwent laparoscopic cholecystectomy for acute cholecystitis between 2015 and 2021. Laparoscopic cholecystectomy for acute cholecystitis was performed by surgeons regardless of whether they were novices or veterans.
    RESULTS: The period from April 2015 to March 2019 was before the introduction (BI) of our approach, the period from April 2019 to December 2021 was after the introduction (AI) of our approach. There were 177 and 186 patients with acute cholecystitis during the BI and AI periods, respectively. There were no significant differences between groups in terms of preoperative characteristics, operative time, and blood loss. No difference in the laparoscopic subtotal cholecystectomy rate between groups (10.2% [BI] vs. 13.9% [AI]; p = 0.266) was obserbed. The open conversion rate during the BI period was significantly higher than that during the AI period (7.4% vs. 1.6%; p = 0.015).
    CONCLUSIONS: Our goal-oriented approach is feasible, safe, and easy for many surgeons to understand.
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  • 文章类型: Journal Article
    当目标是帮助患者提高生活质量时,直接关注对每个患者最重要的活动和关系是有意义的。这可以通过以下三个步骤来最有效地完成,包括1)与患者联系,2)共同创建以目标为导向的计划,和3)与病人合作,家庭,团队成员,和顾问来增加成功的概率。一旦掌握了这种方法和必要的系统,进程,关系已经到位,这不应该比面向问题的方法花费更多的时间,几乎可以肯定,这对医生和患者来说都会更令人满意。对基于人群的质量指标的影响是不确定的。尽管更少的患者可能会选择遵循标准建议,那些这样做的人可能更有可能坚持他们。
    When the goal is to help patients improve their quality of life, it makes sense to focus directly on the activities and relationships that are most important to each patient. This can be accomplished most effectively by following a three-step process that includes 1) connecting with the patient around what matters to them, 2) co-creating a goal-oriented plan, and 3) collaborating with patient, family, team members, and consultants to increase the probability of success. Once this approach has been mastered and the necessary systems, processes, and relationships are in place, this should not take more time than a problem-oriented approach, and it will almost certainly be more satisfying for both physician and patient. The impact on population-based quality metrics is uncertain. Though fewer patients may choose to follow standard recommendations, those who do may be more likely to adhere to them.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    自愿国家审查(VNR)为参与国提供了一个分享经验的平台,失败,以及在实现联合国(UN)可持续发展目标(SDG)方面的成功。本研究的目的是对叙事元素有更深入的理解,尤其是情绪,为了更有效地评估和支持全球可持续发展目标的进展。使用基于方面的情绪分析(ABSA)分析了来自166个国家的232个VNR,以提取每个国家对17个可持续发展目标的情绪。然后将情绪得分与相应的官方联合国可持续发展目标得分进行比较,各国根据对所有17个可持续发展目标的看法进行分组,以确定潜在的共同发展途径。该分析发现,报告的情绪与SDG2(零饥饿)和SDG11(可持续城市和社区)的官方SDG得分之间存在显著正相关。与SDG5(性别平等)呈负相关。相反,这种关系对大多数可持续发展目标来说并不重要,这表明VNR叙述可能不能直接反映实际进展。t分布随机邻居嵌入(t-SNE)方法表明发达国家之间的情绪得分一致。相比之下,新兴市场在报告情绪上有更大的差异,前沿市场,最不发达国家,在报告可持续发展目标进展方面存在更大的分散(特别是在最不发达国家之间)和情绪,这种情绪似乎从一个报告年到另一个报告年都发生了变化。这些发现强调了在每个国家的独特情况和每个国家特有的挑战的背景下解释VNR的必要性。
    Voluntary National Reviews (VNRs) provide a platform for participating countries to share their experiences, failures, and successes in achieving the United Nations (UN) Sustainable Development Goals (SDGs). The objective of this study is to gain a deeper understanding of the narrative elements, particularly the sentiment, in VNRs in order to more effectively assess and support global SDG progress. A total of 232 VNRs from 166 countries are analyzed using Aspect-Based Sentiment Analysis (ABSA) to extract each country\'s sentiment toward the 17 SDGs. The sentiment scores are then compared to the corresponding official UN SDG scores, and countries are grouped by their sentiment toward all 17 SDGs to identify potential common development pathways. The analysis uncovers a notable positive correlation between the reported sentiment and official SDG scores for SDG 2 (zero hunger) and SDG 11 (sustainable cities and communities), and a negative correlation for SDG 5 (gender equality). Conversely, this relationship is not significant for the majority of SDGs, suggesting that VNR narratives may not directly reflect actual progress. A t-distributed stochastic neighbor embedding (t-SNE) approach indicates a consistent sentiment score among developed countries. In contrast, there are greater differences in reporting sentiment among Emerging Markets, Frontier Markets, and Least Developed Countries (LDCs), where there is greater dispersion (especially among LDCs) and sentiment in reporting on SDG progress that appears to have changed from one reporting year to another. These findings highlight the need to interpret VNRs in the context of each country\'s unique situation and challenges specific to each country.
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  • 文章类型: Journal Article
    本研究在可持续发展目标(SDGs)的背景下系统地评估了仿生研究,以辨别仿生与SDGs之间的跨学科相互作用。生物仿生与关键可持续发展目标的结合展示了其跨学科性质和为整个健康领域提供解决方案的潜力,可持续性和能源部门。这项研究确定了两个主要的专题组。第一个专题组侧重于健康,伙伴关系,和陆地生命(可持续发展目标3、17和15),强调仿生学在医疗保健创新中的作用,可持续合作,和土地管理。这个集群展示了仿生对医疗技术做出贡献的潜力,强调跨部门伙伴关系和生态系统保护的必要性。第二个专题组围绕清洁水,能源,基础设施,和海洋生物(可持续发展目标6、7、9和14),展示自然启发的可持续发展挑战解决方案,包括能源生产和水净化。可持续发展目标7在该集群中的突出地位表明,仿生对可持续能源实践做出了重大贡献。对专题组的分析进一步揭示了仿生的广泛适用性及其在加强可持续能源获取和促进生态系统保护方面的作用。新兴的研究课题,比如元启发式,纳米发电机,外泌体,和生物打印,表示一个有望取得重大进展的动态字段。通过绘制生物模拟和可持续发展目标之间的联系,这项研究提供了该领域轨迹的全面概述,强调其在推进全球可持续发展努力中的重要性。
    This study systematically evaluates biomimicry research within the context of sustainable development goals (SDGs) to discern the interdisciplinary interplay between biomimicry and SDGs. The alignment of biomimicry with key SDGs showcases its interdisciplinary nature and potential to offer solutions across the health, sustainability, and energy sectors. This study identified two primary thematic clusters. The first thematic cluster focused on health, partnership, and life on land (SDGs 3, 17, and 15), highlighting biomimicry\'s role in healthcare innovations, sustainable collaboration, and land management. This cluster demonstrates the potential of biomimicry to contribute to medical technologies, emphasizing the need for cross-sectoral partnerships and ecosystem preservation. The second thematic cluster revolves around clean water, energy, infrastructure, and marine life (SDGs 6, 7, 9, and 14), showcasing nature-inspired solutions for sustainable development challenges, including energy generation and water purification. The prominence of SDG 7 within this cluster indicates that biomimicry significantly contributes to sustainable energy practices. The analysis of thematic clusters further revealed the broad applicability of biomimicry and its role in enhancing sustainable energy access and promoting ecosystem conservation. Emerging research topics, such as metaheuristics, nanogenerators, exosomes, and bioprinting, indicate a dynamic field poised for significant advancements. By mapping the connections between biomimicry and SDGs, this study provides a comprehensive overview of the field\'s trajectory, emphasizing its importance in advancing global sustainability efforts.
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    人们经常遇到各种类型的冲突。这里,我们会问,and,如果是,如何,不同类型的冲突,从实验室的Stroop冲突到日常生活的自我控制或道德冲突,彼此相关。我们提出了一个框架,假设行动目标表示是分层组织的,从具体行动到抽象目标。框架的关键假设是涉及更抽象目标的冲突(例如,自我控制/道德冲突)嵌入在更复杂的行动空间中;因此,为了解决这些冲突,人们需要考虑更多相关的目标和行动。我们讨论了复杂性的差异如何影响冲突解决机制以及解决冲突的成本/收益。总之,我们提供了一种新的方法来概念化和分析跨不同领域的冲突监管。
    People regularly encounter various types of conflict. Here, we ask if, and, if so, how, different types of conflict, from lab-based Stroop conflicts to everyday-life self-control or moral conflicts, are related to one other. We present a framework that assumes that action-goal representations are hierarchically organized, ranging from concrete actions to abstract goals. The framework\'s key assumption is that conflicts involving more abstract goals (e.g., self-control/moral conflict) are embedded in a more complex action space; thus, to resolve such conflicts, people need to consider more associated goals and actions. We discuss how differences in complexity impact conflict resolution mechanisms and the costs/benefits of resolving conflicts. Altogether, we offer a new way to conceptualize and analyze conflict regulation across different domains.
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  • 文章类型: Journal Article
    新任务通常是分阶段学习的,每个阶段都反映了不同的学习挑战。因此,每个学习阶段都可能由不同的神经元过程介导。然而,大多数啮齿动物对目标导向学习的神经元相关性的研究集中在个体结局指标和个体大脑区域。这里,我们纵向研究了小鼠从幼稚到专家的头部固定表现,操作调理晶须辨别任务。除了跟踪刺激歧视的主要行为结果,我们跟踪并比较了一系列基于对象和基于时间的行为度量。这些行为分析确定了多个,在这个任务中部分重叠的学习阶段,与初始响应实施一致,早期刺激-反应概括,和后期反应抑制。为了开始理解这些学习过程的神经元基础,我们在整个学习过程中对背侧新皮质进行了宽视野Ca2+成像,并将行为测量值与神经元活动相关联.我们发现新皮层激活模式与各种行为措施之间存在明显而广泛的相关性。例如,感觉辨别的改善与目标刺激引起的反应相关皮质的激活以及干扰刺激引起的整体皮质抑制相关。我们的研究揭示了一个简单的目标导向学习任务的多维学习,并为这些各种学习过程背后的神经元调制生成了假设。
    New tasks are often learned in stages with each stage reflecting a different learning challenge. Accordingly, each learning stage is likely mediated by distinct neuronal processes. And yet, most rodent studies of the neuronal correlates of goal-directed learning focus on individual outcome measures and individual brain regions. Here, we longitudinally studied mice from naïve to expert performance in a head-fixed, operant conditioning whisker discrimination task. In addition to tracking the primary behavioral outcome of stimulus discrimination, we tracked and compared an array of object-based and temporal-based behavioral measures. These behavioral analyses identify multiple, partially overlapping learning stages in this task, consistent with initial response implementation, early stimulus-response generalization, and late response inhibition. To begin to understand the neuronal foundations of these learning processes, we performed widefield Ca2+ imaging of dorsal neocortex throughout learning and correlated behavioral measures with neuronal activity. We found distinct and widespread correlations between neocortical activation patterns and various behavioral measures. For example, improvements in sensory discrimination correlated with target stimulus evoked activations of response-related cortices along with distractor stimulus evoked global cortical suppression. Our study reveals multidimensional learning for a simple goal-directed learning task and generates hypotheses for the neuronal modulations underlying these various learning processes.
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