本文的目的是介绍一名50岁女性的大型外周骨化性纤维瘤的临床病例,该病例是从先前诊断的化脓性肉芽肿演变而来的。该患者被转诊以治疗左上第一磨牙附近的颊和腭牙龈上的病变。颜色是紫红色,直径约3厘米,有一个光滑的表面,一个带蒂出血的底座,经过七年的进化,被诊断为化脓性肉芽肿.经过三年的逃避,患者返回报告病变增加和进食困难。临床上结节外观为小叶,粉红色的颜色和光滑,有蒂,公司的一致性,无出血,最大的延伸大约5厘米,延伸到上颌结节。切除病灶并进行组织病理学检查,这导致了周围骨化性纤维瘤的诊断。患者随访约18个月,修复,愈合满意,无复发临床征象。在这种情况下,观察到化脓性肉芽肿可能演变为周围骨化性纤维瘤,根据发生的组织病理学变化,随着钙化物质的发展,纤维成熟,三年后,初始病变的血管含量降低。
The aim of the present article is to present the clinical case of a large peripheral ossifying fibroma that evolved from a previously diagnosed pyogenic granuloma in a 50-year-old woman. The patient was referred for treatment of a lesion over the buccal and palatal gingiva close to the left upper first molar. It was purplish-red in color, approximately 3 cm in diameter, having a smooth surface, a pedicled and bleeding base, with seven years of evolution, and diagnosed as pyogenic granuloma. After three years of evasion, the patient returned reporting an increase in the lesion and difficulty in eating. Clinically the nodule was lobular in appearance, pink in color and smooth, pediculated, firm in consistency, non-bleeding, about 5 cm in its greatest extension, extending to the maxillary tuberosity. The lesion was excised and referred for histopathological examination, which led to the diagnosis of peripheral ossifying fibroma. The patient was followed for approximately 18 months, prosthetically rehabilitated, with satisfactory healing and no clinical signs of recurrence. The possible evolution of a pyogenic granuloma to a peripheral ossifying fibroma was observed in this case, based on the histopathological changes that occurred, with the development of calcified material, fibrous maturation, and decreased vascular content of the initial lesion after three years.