目的:探讨生殖道B族链球菌(GBS)感染孕妇血清炎症因子的变化及其对胎膜早破(PROM)并发绒毛膜羊膜炎(CS)及不良妊娠结局的预测价值。方法:采用ELISA法评价血清炎症因子水平对GBS感染孕妇PROM并发CS及不良妊娠结局的预测价值。结果:血清IL-6、TNF-α、GBS感染孕妇PCT和hs-CRP水平较高。这些因素的联合诊断对PROM合并CS及不良妊娠结局具有良好的诊断价值。结论:联合预测IL-6、TNF-α、PCT和hs-CRP对PROM并发CS和不良妊娠结局的预测价值最好。
Objective: The aim of this study as to unveil changes in serum inflammatory factors in pregnant women with genital tract group B Streptococcus (GBS) infection and their predictive value for premature rupture of membranes (PROM) complicated by chorioamnionitis (CS) and adverse pregnancy outcomes. Methods: The value of serum inflammatory factor levels in predicting PROM complicating CS and adverse pregnancy outcomes in GBS-infected pregnant women was evaluated by ELISA. Results: Serum IL-6, TNF-α, PCT and hs-CRP levels were higher in pregnant women with GBS infection. The combined diagnosis of these factors had excellent diagnostic value in PROM complicating CS and adverse pregnancy outcomes. Conclusion: Joint prediction of IL-6, TNF-α, PCT and hs-CRP has the best predictive value for PROM complicating CS and adverse pregnancy outcomes.
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