背景:术后咽喉痛(POST)是一种令人不快的结果,可作为成人气管插管的结果。气管内导管(ETT)袖带的压力增加通常会导致局部粘膜损伤,导致喉咙痛。这项研究的目的是比较两种不同的ETT袖带压力监测系统与没有袖带压力监测成人POST的发生率和严重程度。
方法:114名ASAI-III患者,18-65岁,和需要气管内插管的手术包括在这项研究中。患者被随机分为三组:对照组(C),袖带压力表(G),和自动袖带控制器(A)。C组术中不监测ETT袖带压力,但在G组和A组中使用袖带压力计和自动袖带控制器监测,分别。术后,在2、24和48小时评估患者POST的存在和严重程度,声音嘶哑和咳嗽.
结果:111名患者完成了这项研究。术后48小时内G组40.5%的患者(n=37)(p=0.013)和A组23.7%的患者(n=38)(p<0.001)发生POST,C组为69.4%(n=36)。声音嘶哑没有显着差异,咳嗽,和吞咽困难。当比较A组和C组时,A组个体表现出较低的显著(≥2级)POST和声音嘶哑发生率(10.5%vs.41.7%,p=0.002;26.3%vs.58.3%,p=0.005)。手术后48小时内,患者组之间的严重咳嗽和吞咽困难的发生率没有显着差异。A组术后2、24h的POST评分均为0(0~0),2h时显著低于C组(1(0-2),p<0.001;24小时为1(0-1),p=0.001)。G组术后2h的POST评分为0(0-1.5),低于C组(P=0.024)。A组声音嘶哑程度0分(0~2分)优于C组(2分(0~2分),术后2小时p=0.006)。
结论:结论:这项研究的结果表明,可以通过使用袖带压力表方法或自动袖带控制器方法来减少POST的发生。自动袖带控制器监测可以潜在地降低POST和声音嘶哑的严重性。
背景:中国临床试验注册中心,标识符:ChiCTR2100054089,日期:08/12/2021.
BACKGROUND: Postoperative sore throat (POST) is an unpleasant outcome that can occur as a result of tracheal intubation in adults. Increased pressure from the endotracheal tube (ETT) cuff often leads to local mucosal injury, resulting in sore throat. The purpose of this study was to compare the effect of two different ETT cuff pressure monitoring systems vs. no cuff pressure monitoring on the incidence and severity of POST in adults.
METHODS: One hundred and fourteen ASA I-III patients of either gender, aged 18-65 years, and undergoing surgery requiring endotracheal intubation were included in this study. Patients were randomized into three groups: control (C), cuff pressure
gauge (G), and automated cuff controller (A). The ETT cuff pressure was not monitored intraoperatively in group C but was monitored using a cuff pressure
gauge and an automated cuff controller in groups G and A, respectively. Postoperatively, patients were assessed at 2, 24, and 48 h for the presence and severity of POST, hoarseness and cough.
RESULTS: One hundred and eleven patients completed the study. POST occurred in 40.5% of the patients in group G (n = 37) (p = 0.013) and 23.7% of the patients in group A (n = 38) (p < 0.001) within 48 h after surgery, compared to 69.4% in group C (n = 36). There were no significant differences in hoarseness, coughing, and dysphagia across the groups at any time. When comparing groups A and C, individuals in group A exhibited a lower occurrence of significant (grade ≥ 2) POST and hoarseness (10.5% vs. 41.7%, p = 0.002; 26.3% vs. 58.3%, p = 0.005). The incidence of significant cough and dysphagia did not differ substantially across the patient groups within 48 h after surgery. POST scores in group A at 2, 24 h postoperatively were both 0 (0-0), which was significantly lower than those in group C (1 (0-2) at 2 h, p < 0.001 ; 1 (0-1) at 24 h, p = 0.001). POST in group G at 2 h postoperatively was graded as 0 (0-1.5) which was milder than group C (P = 0.024). The severity of hoarseness in group A with scores of 0 (0-2) was superior to that in group C (2 (0-2), p = 0.006) at 2 h postoperatively.
CONCLUSIONS: In conclusion, the findings of this study indicated that the occurrence of POST can be reduced by using either the cuff pressure
gauge approach or the automated cuff controller method. The automated cuff controller monitoring can potentially decrease the severity of POST and hoarseness.
BACKGROUND: Chinese Clinical Trial Registry, identifier: ChiCTR2100054089, Date: 08/12/2021.