fungal infection 

  • 文章类型: Case Reports
    鼻窦肉芽肿性病变与多种疾病相关,包括结节病等免疫疾病,血管炎,免疫球蛋白G4(IgG4)相关疾病,恶性淋巴瘤,和微生物感染。这里,我们报告了一例罕见的真菌性肉芽肿,仅发生在鼻中隔。该患者向外科部门就诊,主要主诉与鼻中隔偏曲相关的鼻塞。在右鼻中隔下方发现了一个凸起。最初,它被诊断为与鼻炎相关的粘膜肿胀,并进行了手术。在鼻中隔粘膜下发现肉芽肿性病变伴骨质破坏,这导致了基于术后病理的真菌肉芽的诊断。尽管偶尔会观察到鼻中隔的细菌和真菌感染,这是首次报道的局限于鼻中隔的真菌性肉芽肿。鼻中隔感染,虽然罕见,也应考虑作为鼻中隔形态异常的鉴别诊断。
    Granulomatous lesions in the nasal sinuses are associated with a variety of diseases, including immune disorders such as sarcoidosis, vasculitis, immunoglobulin G4 (IgG4)-related diseases, malignant lymphomas, and microbial infections. Here, we report a rare case of fungal granuloma that occurred exclusively within the nasal septum. The patient presented to the Department of Surgery with the chief complaint of nasal obstruction associated with nasal septal deviation. A bulge was found below the right nasal septum. Initially, it was diagnosed as mucosal swelling associated with rhinitis, and surgery was performed. A granulomatous lesion with bone destruction was found under the mucosa of the nasal septum, which led to the diagnosis of fungal granulation based on postoperative pathology. Though bacterial and fungal infections of the nasal septum are occasionally observed, this is the first reported instance of a fungal granuloma confined to the nasal septum. Infection within the nasal septum, although rare, should also be considered as a differential diagnosis for morphological abnormalities of the nasal septum.
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  • 文章类型: Case Reports
    带状疱疹(HZ)感染是由水痘-带状疱疹病毒(VZV)的重新激活引起的,在浅表真菌感染部位很少有报道。此外,在深部真菌感染部位发生的HZ尚未在文献中报道。我们讨论了一例45岁男性患者的独特病例,该患者表现为伴有播散性HZ的Majocchi肉芽肿(MG)。
    Herpes zoster (HZ) infection is caused by the reactivation of the varicella-zoster virus (VZV) and has very rarely been reported at the site of a superficial fungal infection. Also, HZ occurring at the site of a deep fungal infection has not been reported in the literature. We discuss a unique case of a 45-year-old male patient presenting with a Majocchi granuloma (MG) superinfected with disseminated HZ.
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  • 文章类型: Journal Article
    背景:皮肤病和精神疾病之间的关系是双向的,表现为因果关系。精神疾病,如压力,焦虑,一方面,抑郁症被认为是皮肤病的发展和进展的工具,而另一方面,皮肤病引起的美容毁容是患者心理困扰的原因。进行本研究是为了调查精神病患者的皮肤病谱,为他们提供整体治疗并为他们提供更好的生活质量。
    方法:这个横截面,观察性研究是在三级医疗中心进行的.该研究共招募了170名因不同皮肤病学表现而转诊到皮肤科的精神病患者。做了病人的人口统计资料,并做了皮肤病和精神疾病之间的关联。
    结果:在170名研究参与者中,88(51.8%)为女性,其余(82,48.2%)为男性。总共记录了13种主要的皮肤病;其中,真菌感染(43,25.3%)是最常见的,其次是湿疹(18%,10.6%),寄生虫感染(17,10.0%),色素性障碍(13,7.6%),痤疮(11,6.5%),细菌感染(11,6.5%),瘙痒性疾病(11,6.5%),毛发紊乱(9,5.3%),药物反应(9,5.3%),丘疹鳞状疾病(7,4.1%),和病毒感染(6,3.5%)。在15名(8.8%)患者中存在上述以外的皮肤状况。本研究中最常见的精神疾病是重度抑郁症(41,24.1%),其次是广泛性焦虑症(38,22.4%)和精神病没有其他说明(34,20.0%)。研究中包括的其他精神疾病是双相情感障碍(22,12.9%),精神分裂症(18,10.6%),强迫症(12,7.1%),和混合焦虑抑郁障碍(5,2.9%)。
    结论:本研究的发现表明,具有皮肤病学表现的精神病患者表现出一系列皮肤病。主要是传染性(真菌,寄生,或病毒)性质。这可能与精神病患者的卫生状况相对较差有关,因此他们对这些疾病的易感性增加。大多数时候,对这些皮肤状况的易感性似乎是机会性的,不受类型的影响,持续时间,和精神疾病的控制水平。
    BACKGROUND: The relationship between skin diseases and psychiatric illnesses is bi-directional and is manifested as cause and effect. Psychiatric disorders such as stress, anxiety, and depression are seen to be instrumental in the development and progression of dermatological diseases on one hand, while on the other hand, cosmetic disfigurement caused by dermatological diseases is responsible for psychological distress in patients. The present study was conducted to investigate the spectrum of dermatological disorders in psychiatric patients to offer them holistic treatment and provide them with a better quality of life.
    METHODS: This cross-sectional, observational study was conducted at a tertiary medical care center. A total of 170 psychiatric patients referred to the dermatology department for different dermatological manifestations were enrolled in the study. A demographic profile of the patients was done, and an association between dermatological diseases and psychiatric illnesses was done.
    RESULTS:  Out of 170 study participants, 88 (51.8%) were females, and the rest (82, 48.2%) were males. A total of 13 major types of dermatological conditions were noted; among them, fungal infection (43, 25.3%) was the most common, followed by eczema (18, 10.6%), parasitic infestation (17, 10.0%), pigmentary disorder (13, 7.6%), acne (11, 6.5%), bacterial infection (11, 6.5%), pruritic disorder (11, 6.5%), hair disorder (9, 5.3%), drug reaction (9, 5.3%), papulosquamous disorder (7, 4.1%), and viral infection (6, 3.5%). Skin conditions other than the above-mentioned were present in 15 (8.8%) patients. The most common psychiatric illness in the present study was major depressive disorder (41, 24.1%), followed by generalized anxiety disorder (38, 22.4%) and psychosis not otherwise specified (34, 20.0%). Other psychiatric illnesses included in the study were bipolar affective disorder (22, 12.9%), schizophrenia (18, 10.6%), obsessive-compulsive disorder (12, 7.1%), and mixed anxiety depressive disorder (5, 2.9%).
    CONCLUSIONS: The findings of the present study depict that psychiatric patients with dermatological manifestations show a spectrum of dermatological conditions, primarily of infectious (fungal, parasitic, or viral) nature. This might be associated with a relatively poor hygienic status of psychiatric patients and thus their increased susceptibility to these disorders. Most of the time, the susceptibility to these skin conditions seemed to be opportunistic and unaffected by the type, duration, and level of control of psychiatric illness.
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  • 文章类型: Case Reports
    胃肠道担子菌病(GIB)是一种罕见的真菌感染引起的ranarum,一种腐生真菌,属于担子菌类。它主要感染有免疫能力的个体,主要见于干旱的热带和亚热带地区,包括美国西南部,沙特阿拉伯,非洲,和亚洲。毫不奇怪,据报道,大量的人类感染来自这些温暖,适合这种真菌生长的湿润气候区域,特别是来自沙特阿拉伯和美国亚利桑那州的南部地区。GIB容易误诊为恶性肿瘤,炎症性肠病,憩室炎,淋巴瘤以及罕见的慢性肠道感染。在这个系列中,我们总结了临床特征,成像,组织病理学特征,以及在我们机构诊断为GIB的患者的治疗。
    Gastrointestinal basidiobolomycosis (GIB) is a rare fungal infection caused by Basidiobolus ranarum, a saprophytic fungus that belongs to the class of Basidiobolomycetes. It mainly infects immunocompetent individuals and is mainly found in arid tropical and subtropical regions, including Southwestern America, Saudi Arabia, Africa, and Asia. Not surprisingly, a great number of human infections have been reported from these warm, humid climate regions that are felicitous for the growth of this fungus, especially from the southern region of Saudi Arabia and Arizona in the United States of America. GIB is easily misdiagnosed as malignancy, inflammatory bowel disease, diverticulitis, lymphoma, and chronic intestinal infections due to its rarity. In this case series, we summarize the clinical features, imaging, histopathological features, and treatment of patients diagnosed with GIB in our institution.
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  • 文章类型: Journal Article
    目标:在印度的皮肤科门诊部,皮肤癣菌病是最常见的皮肤病。目的是收集有关非处方药(OTC)患病率的数据,疾病的知识,以及各种社会经济类别的皮肤癣菌感染人群的卫生习惯。
    方法:在印度中部的三级护理机构,进行了为期6个月的横断面研究.关于社会经济阶层的数据,卫生习惯,任何类型的治疗的既往史,了解病情,并记录了类似疾病的家族史。共有551名患者被纳入研究。使用Spearman相关系数(rho)评估相关性。
    结果:社会经济课程对寻求皮肤科医生的建议影响不大。所有患者中约有81.8%使用类固醇。类固醇的使用与病情的严重程度之间存在正相关(rho=0.237)。大约34%的患者服用处方药,根据药剂师的建议。类固醇的使用与药剂师的处方呈正相关(rho=0.426,p<0.001)。非处方药的供应和相信药剂师有资格识别和治疗疾病的个人是重要的原因。
    结论:所有社会经济阶层的人们都需要更多地意识到与不适当使用药物和一般皮肤问题相关的风险。严格的法规来控制处方药的销售并阻止替代医学的从业者开出对抗疗法的药物可能是有益的。
    OBJECTIVE: In dermatology outpatient departments in India, dermatophytosis is the most commonly encountered dermatosis. The objective was to collect data regarding the prevalence of over-the-counter (OTC) medication, knowledge of the illness, and hygiene habits among people with dermatophyte infections across various socioeconomic classes.
    METHODS: At a tertiary care facility in central India, a cross-sectional study was carried out over six months. Data about socioeconomic class, hygiene routines, prior history of any type of treatment, understanding of the condition, and family history of similar illnesses were noted. A total of 551 patients were included in the study. The correlation was evaluated using Spearman\'s correlation coefficient (rho).
    RESULTS: Socioeconomic class had little impact on seeking dermatologist advice. Steroids were prescribed to approximately 81.8% of all patients. There was a positive correlation (rho = 0.237) between the use of steroids and the severity of the condition. Around 34% of patients took prescription medications, as recommended by a pharmacist. The use of steroids positively correlated (rho = 0.426, p<0.001) with prescriptions by pharmacists. Over-the-counter drug availability and individuals believing pharmacists were qualified to identify and treat illnesses were significant contributing causes.
    CONCLUSIONS: People from all socioeconomic strata need to be made more aware of the risks associated with the inappropriate use of medications and skin problems in general. Strict regulations to control prescription drug sales and deter practitioners of alternative medicine from prescribing allopathic medications may be beneficial.
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