framework

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  • 文章类型: Journal Article
    发光共价有机骨架(COF)是一类有前途的晶体材料,已证明可用于传感和发光二极管。然而,单一COF发出的白光尚未实现,因为它需要同时发出蓝色的多组分有机发色团,绿色,和红灯。在这项工作中,我们报道了在其核心结构上掺入不同官能团后,利用2,1,3-苯并噻二唑的可调发射性能,成功合成了具有有效白光发射的单一COF,这导致三个配体的形成,即,4\',4-(苯并噻二唑-4,7-二基)-二苯甲醛(BTD),4,4'-(苯并硒二唑-4,7-二基)-二苯甲醛(BSD),和4,4'-(萘并[2,3-c][1,2,3]硒二唑-4,9-二基)-二苯甲醛(NSD),发出蓝色,绿色,和可见光谱的红色区域。我们表明,只有当BTD,BSD,和NSD由于从BTD到BSD/NSD的促进的能量转移过程而组装在单个COF结构中。这项工作展示了一种独特的方法来开发基于COF结构的新型白色发光材料。
    Emissive covalent organic frameworks (COFs) are a promising class of crystalline materials that have demonstrated applications for sensing and light-emitting diodes. However, white light emission from a single COF has not been achieved yet as it requires multicomponent organic chromophores that simultaneously emit blue, green, and red light. In this work, we report the successful synthesis of a single COF with efficient white light emission by utilizing tunable emission properties of 2,1,3-benzothiadazole after incorporating different functional groups on its core structure, which results in the formation of three ligands, i.e., 4\',4-(benzothiadiazole-4,7-diyl)-dibenzaldehyde (BTD), 4,4\'-(benzoselenadiazole-4,7-diyl)-dibenzaldehyde (BSD), and 4,4\'-(naphtho[2,3-c][1,2,3] selenadiazole-4,9-diyl)-dibenzaldehyde (NSD), that emit in the blue, green, and red regions of the visible light spectrum. We show that white light emission can only occur when BTD, BSD, and NSD are assembled in a single COF structure due to the facilitated energy transfer process from BTD to BSD/NSD. This work demonstrates a unique approach to developing new white light-emitting materials based on the COF structure.
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  • 文章类型: Journal Article
    基于废水的流行病学(WBE)是一种通过分析污水来监测社区健康的环境方法。COVID-19大流行促使科学家和公共卫生专业人员重新审视WBE,将其作为优化资源分配以减轻疾病传播和预防暴发的工具。一些研究强调了与公共卫生专业人员协调的WBE计划的价值;然而,实施所需的细节没有很好地描述。为了应对这种知识差距,本文记录了亚利桑那州成功的WBE计划的框架,战术流行病学反应系统(WATERS)的废水分析,详细说明了建立公共卫生准备和应对行动的通信结构和方法。此通信说明了如何采用程序操作来降低爆发严重性。此处概述的结构是可定制的,可以指导其他程序将WBE作为公共卫生工具实施。
    Wastewater-based epidemiology (WBE) is an environmental approach to monitor community health through the analysis of sewage. The COVID-19 pandemic catalyzed scientists and public health professionals to revisit WBE as a tool to optimize resource allocation to mitigate disease spread and prevent outbreaks. Some studies have highlighted the value of WBE programs that coordinate with public health professionals; however, the details necessary for implementation are not well-characterized. To respond to this knowledge gap, this article documents the framework of a successful WBE program in Arizona, titled Wastewater Analysis for Tactical Epidemiological Response Systems (WATERS), detailing the developed structure and methods of communication that enabled public health preparedness and response actions. This communication illustrates how program operations were employed to reduce outbreak severity. The structure outlined here is customizable and may guide other programs in the implementation of WBE as a public health tool.
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  • 文章类型: Journal Article
    背景:在美国,早产(PTB)率很高,黑人婴儿仍然受到不成比例的影响,今天黑人和白人婴儿死亡的差距比战前奴隶制下的差距更大。
    目标:国家少数民族健康与差异研究所研究框架反映了一套与理解和促进少数民族健康相关的独特决定因素。
    方法:我们已经应用此框架来更好地了解PTB对黑人父母的影响以及健康的社会决定因素的分布,包括结构决定因素和不平等的根本原因。
    结论:这种适应显示了母婴健康的交集,塑造了个人的经验,在生命周期的关键时期驱动差异并影响围产期结局。
    结论:在我们实现健康公平的努力中,我们必须研究潜在的机制,并认识到政策,体制结构,社会因素是种族主义的驱动因素。
    BACKGROUND: The rate of preterm birth (PTB) is high in the United States and Black infants remain disproportionately affected, with the disparity between Black and White infant deaths greater today than it was under antebellum slavery.
    OBJECTIVE: The National Institute on Minority Health and Disparities Research Framework reflects a unique set of determinants relevant to the understanding and promotion of minority health.
    METHODS: We have applied this framework to better understand the effects of PTB on Black parents and the distribution of the social determinants of health, including structural determinants and root causes of inequities.
    CONCLUSIONS: This adaptation shows the intersection in maternal and infant health that shapes individuals\' experiences, drives disparities and impacts perinatal outcomes in critical periods over the lifecourse.
    CONCLUSIONS: In our efforts to achieve health equity, it is imperative that we study the underlying mechanisms and recognize that policies, institutional structures, and social factors are drivers of racism.
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  • 文章类型: Journal Article
    背景:/目标取消实施,包括删除或减少不必要或不适当的处方,对于确保患者获得适当的循证医疗保健至关重要。取消执行工作的利用取决于战略报告的质量。为了进一步了解取消医疗实践的有效方法,需要规范行为目标和取消实施战略的组成部分。本文旨在批判性地分析行为目标和战略组成部分的好坏,在专注于在二级医疗保健环境中取消不必要或不适当处方的研究中,被报道。
    方法:对最近发表的取消实施研究综述中的研究进行了补充分析。文章文本被逐字编码到两个既定的规范框架中。行为成分被演绎地编码为行动的五个要素,演员,上下文,目标,时间(AACTT)框架。战略组件被映射到Proctor的“衡量实施战略”框架的九个元素。
    结果:低价值处方的行为成分,编码到AACTT框架中,一般规定得很好。然而,Actor和Time组件通常含糊不清或没有很好地报告。战略组成部分的规范,编码到Proctor框架中,报道得不太好。Proctor\的演员,行动目标:指定目标,剂量和理由要素没有很好地报告或在提供的细节数量上有所变化。我们还提供其他规格的建议,例如“互动”参与者有一个策略。
    结论:AACTT和Proctor框架联合使用时,可以适应处方实践的行为目标和取消实施策略的组成部分的规范。这些基本细节需要理解,复制并成功取消不必要或不适当的处方。总的来说,这些组件的报告质量标准化是重复任何取消实施工作所必需的。
    背景:未注册。
    BACKGROUND: /Aims De-implementation, including the removal or reduction of unnecessary or inappropriate prescribing, is crucial to ensure patients receive appropriate evidence-based health care. The utilization of de-implementation efforts is contingent on the quality of strategy reporting. To further understand effective ways to de-implement medical practices, specification of behavioural targets and components of de-implementation strategies are required. This paper aims to critically analyse how well the behavioural targets and strategy components, in studies that focused on de-implementing unnecessary or inappropriate prescribing in secondary healthcare settings, were reported.
    METHODS: A supplementary analysis of studies included in a recently published review of de-implementation studies was conducted. Article text was coded verbatim to two established specification frameworks. Behavioural components were coded deductively to the five elements of the Action, Actor, Context, Target, Time (AACTT) framework. Strategy components were mapped to the nine elements of the Proctor\'s \'measuring implementation strategies\' framework.
    RESULTS: The behavioural components of low-value prescribing, as coded to the AACTT framework, were generally specified well. However, the Actor and Time components were often vague or not well reported. Specification of strategy components, as coded to the Proctor framework, were less well reported. Proctor\'s Actor, Action target: specifying targets, Dose and Justification elements were not well reported or varied in the amount of detail offered. We also offer suggestions of additional specifications to make, such as the \'interactions\' participants have with a strategy.
    CONCLUSIONS: Specification of behavioural targets and components of de-implementation strategies for prescribing practices can be accommodated by the AACTT and Proctor frameworks when used in conjunction. These essential details are required to understand, replicate and successfully de-implement unnecessary or inappropriate prescribing. In general, standardisation in the reporting quality of these components is required to replicate any de-implementation efforts.
    BACKGROUND: Not registered.
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  • 文章类型: Journal Article
    OneHealth是一种跨学科方法,通过跨多个学科的合作来促进复杂健康问题的解决。除了问责制,一个健康治理结构促进了共同的理解,信任,以及对不同观点和要求的欣赏。本文全面分析了当前在中国现有卫生治理框架内整合“一个卫生”方法的情况。并提出进一步改进的策略,通过审查当前的卫生政策,强调实施水平和对推进“一个卫生”治理的贡献。
    One Health is an interdisciplinary approach that promotes the resolution of complex health issues through collaboration across multiple disciplines. In addition to accountability, the One Health governance structure fosters shared understanding, trust, and an appreciation for diverse perspectives and requirements. This article provides a comprehensive analysis of the current integration of the One Health approach within China\'s existing health governance framework. It also proposes strategies for further improvement, with emphasis on the level of implementation and contributions to the advancement of One Health governance through an examination of current health policies.
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  • 文章类型: Journal Article
    尽管显示来自合格临床数据登记处(QCDR)的性能数据的仪表板激增,临床医生和实践人员参与此类仪表板的程度尚未得到很好的描述。我们旨在开发一个概念框架,用于评估用户对仪表板技术的参与度,并展示其在风湿病学QCDR中的应用。
    我们开发了BDC(广度-深度-上下文)框架,其中包括广度的概念(来自仪表板会话),深度(来自仪表板操作),和背景(源于实践特征)。我们通过来自美国风湿病学会的风湿病信息系统(RISE)注册表的用户日志数据展示了其应用,以定义参与概况并表征与不同概况相关的实践水平因素。
    我们在2020-2021年将BDC框架应用于RISE注册中心的213个动态实践,并将实践分为4个参与概况:未参与(8%),最低限度参与(39%),适度参与(34%),参与度最高(19%)。有更多患者和特定电子健康记录供应商(eClinicalWorks和eMDs)的做法有更高的可能性成为参与程度最高的群体,即使在调整了其他因素之后。
    我们开发了BDC框架来表征用户对注册表仪表板的参与,并演示了其在专业QCDR中的使用。BDC框架的应用揭示了广泛的使用广度和深度,并且特定的环境因素与参与性质相关。
    展望未来,BDC框架可用于研究与类似仪表板的参与度。
    UNASSIGNED: Despite the proliferation of dashboards that display performance data derived from Qualified Clinical Data Registries (QCDR), the degree to which clinicians and practices engage with such dashboards has not been well described. We aimed to develop a conceptual framework for assessing user engagement with dashboard technology and to demonstrate its application to a rheumatology QCDR.
    UNASSIGNED: We developed the BDC (Breadth-Depth-Context) framework, which included concepts of breadth (derived from dashboard sessions), depth (derived from dashboard actions), and context (derived from practice characteristics). We demonstrated its application via user log data from the American College of Rheumatology\'s Rheumatology Informatics System for Effectiveness (RISE) registry to define engagement profiles and characterize practice-level factors associated with different profiles.
    UNASSIGNED: We applied the BDC framework to 213 ambulatory practices from the RISE registry in 2020-2021, and classified practices into 4 engagement profiles: not engaged (8%), minimally engaged (39%), moderately engaged (34%), and most engaged (19%). Practices with more patients and with specific electronic health record vendors (eClinicalWorks and eMDs) had a higher likelihood of being in the most engaged group, even after adjusting for other factors.
    UNASSIGNED: We developed the BDC framework to characterize user engagement with a registry dashboard and demonstrated its use in a specialty QCDR. The application of the BDC framework revealed a wide range of breadth and depth of use and that specific contextual factors were associated with nature of engagement.
    UNASSIGNED: Going forward, the BDC framework can be used to study engagement with similar dashboards.
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  • 文章类型: Journal Article
    背景。尽管移动健康(mHealth)干预措施在改善健康结果方面显示出了希望,他们中的大多数很少转化为规模。目前正在进行的mHealth研究大多规模很小,短期和捐助者资助的试点研究,其有效性的证据有限。为了促进扩大规模,已经提出了几个框架来加强卫生干预措施的一般性实施。然而,在低资源环境中,缺乏对在常规护理中实施和整合mHealth干预措施的具体关注。我们的范围审查旨在综合和开发一个框架,以指导mHealth干预措施的实施和整合。方法:我们搜索了PubMed,谷歌学者,和已发表理论的ScienceDirect数据库,模型,以及与2000年1月1日至2023年12月31日临床干预措施的实施和整合有关的框架。数据处理以Arksey和O\'Malley提出的范围审查方法为指导。如果研究是i)在2000年至2023年之间进行同行评审并发表,ii)明确描述了临床干预实施和整合的框架,或iii)全文可用,并以英文出版。我们从审查的框架中整合了不同的领域和结构,以开发实施和整合mHealth干预措施的新框架。结果:我们确定了8篇合格论文,其中8个框架由102个实施域组成。没有一个已确定的框架专门针对在低资源环境中整合mHealth干预措施。与培训领域相关的两个结构(技能传授和干预意识),四个结构(技术和后勤支持,确定忠诚的员工,监督,并重新设计)从重组领域,来自激励领域的两个结构(货币激励和非货币激励),任务域中的两个构造(组织任务和政府任务)和集成域中的两个构造(协作和常规工作流)。因此,一个新的框架,概述了五个主要领域-训练,重组,激励,任务,和整合(TRIMI)-与在低资源环境中整合和实施mHealth干预措施有关。结论:TRIMI框架为低资源环境中mHealth干预措施的实施和整合缺陷提供了现实可行的解决方案。
    UNASSIGNED: Although mobile health (mHealth) interventions have shown promise in improving health outcomes, most of them rarely translate to scale. Prevailing mHealth studies are largely small-sized, short-term and donor-funded pilot studies with limited evidence on their effectiveness. To facilitate scale-up, several frameworks have been proposed to enhance the generic implementation of health interventions. However, there is a lack of a specific focus on the implementation and integration of mHealth interventions in routine care in low-resource settings. Our scoping review aimed to synthesize and develop a framework that could guide the implementation and integration of mHealth interventions.
    UNASSIGNED: We searched the PubMed, Google Scholar, and ScienceDirect databases for published theories, models, and frameworks related to the implementation and integration of clinical interventions from 1st January 2000 to 31st December 2023. The data processing was guided by a scoping review methodology proposed by Arksey and O\'Malley. Studies were included if they were i) peer-reviewed and published between 2000 and 2023, ii) explicitly described a framework for clinical intervention implementation and integration, or iii) available in full text and published in English. We integrated different domains and constructs from the reviewed frameworks to develop a new framework for implementing and integrating mHealth interventions.
    UNASSIGNED: We identified eight eligible papers with eight frameworks composed of 102 implementation domains. None of the identified frameworks were specific to the integration of mHealth interventions in low-resource settings. Two constructs (skill impartation and intervention awareness) related to the training domain, four constructs (technical and logistical support, identifying committed staff, supervision, and redesigning) from the restructuring domain, two constructs (monetary incentives and nonmonetary incentives) from the incentivize domain, two constructs (organizational mandates and government mandates) from the mandate domain and two constructs (collaboration and routine workflows) from the integrate domain. Therefore, a new framework that outlines five main domains-train, restructure, incentivize, mandate, and integrate (TRIMI)-in relation to the integration and implementation of mHealth interventions in low-resource settings emerged.
    UNASSIGNED: The TRIMI framework presents a realistic and realizable solution for the implementation and integration deficits of mHealth interventions in low-resource settings.
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  • 文章类型: Journal Article
    黎巴嫩和冲突地区的学童和青少年精神健康障碍患病率显著上升,因此需要立即采取干预措施。尽管患病率上升,这些社区目前缺乏有效的计划,这些计划清楚地确定了在学童中促进和预防心理健康的概念。解决这个差距,本文旨在为教育工作者提出一个情境模型和框架,研究人员和政策制定者。所提出的模型包括3个级别,包括一组行动和干预措施。每个级别采用的干预措施应进行微调,以产生一个关怀和支持性的学习环境,有效地纳入学生心理健康的三个基本领域:促进心理健康保护因素,特别是社交和情感学习(SEL)和韧性,以及预防精神健康障碍(MHD)。框架中详细阐述了每个级别的干预措施,并将其与学校环境中存在的相应部分联系起来,包括教师,家庭,社区,媒体,和政策制定者。该框架还扩展了这些干预措施,以涵盖SEL的核心能力,弹性,以及预防冲突地区最普遍的精神健康障碍。
    The significant rise in the prevalence of mental health disorders among school children and adolescents in Lebanon and conflict zones necessitate immediate interventions. Despite this elevated prevalence, such communities currently lack effective programs which clearly identify the concepts of mental health promotion and prevention among school children. Addressing this gap, our paper aims to propose a contextual model and framework for educators, researchers and policy-makers. The proposed model includes 3-levels comprising set of actions and interventions. Interventions adopted at each level should be fine-tuned to produce a caring and supportive learning environment that effectively incorporates the three essential domains of student\'s mental health: promoting mental health protective factors, notably social and emotional learning (SEL) and resilience, as well as preventing mental health disorders (MHD). Interventions set at each level are elaborated in the framework and linked to the corresponding segments present in the school environment to include teachers, family, community, media, and policymakers. The framework also extends these interventions to encompass the core competencies of SEL, resilience, as well as the prevention of the most prevalent mental health disorders in conflict zones.
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  • 文章类型: Journal Article
    运动科学家(尤其是在生物分子研究领域)经常将运动队列分类为耐力,力量,或混合,并创建一个实用的框架来研究看似相似的群体之间的不同运动人群。认识到这些分类的局限性和复杂性至关重要,因为它们可能过分简化了每项运动的多维特征。如果是,处理此类方法的研究的有效性可能会受到损害,不同研究之间的可比性具有挑战性或不可能。这种观点批判性地审视并突出了与当前体育类型相关的问题,批评现有的体育分类系统,并强调了建立普遍接受的分类模型的必要性,以提高未来体育生物分子研究的质量。
    Exercise scientists (especially in the field of biomolecular research) frequently classify athletic cohorts into categories such as endurance, strength, or mixed, and create a practical framework for studying diverse athletic populations between seemingly similar groups. It is crucial to recognize the limitations and complexities of these classifications, as they may oversimplify the multidimensional characteristics of each sport. If so, the validity of studies dealing with such approaches may become compromised and the comparability across different studies challenging or impossible. This perspective critically examines and highlights the issues associated with current sports typologies, critiques existing sports classification systems, and emphasizes the imperative for a universally accepted classification model to enhance the quality of biomolecular research of sports in the future.
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  • 文章类型: Journal Article
    食物环境,人们直接参与更广泛的食物系统,可能是粮食系统环境可持续性的重要贡献者。
    这项研究的主要目标是建立一个新的食品环境框架,该框架考虑了环境指标,并使用先前作为4个南亚城市食品系统调查的一部分收集的数据来评估数据可用性和差距。
    该框架是通过对以前的食品环境框架进行结构化的文献回顾以及与内容专家的深入访谈(n=6)而开发的。然后将框架和指标映射到消费者和供应商调查收集的数据,使用城市粮食系统评估工具(UFSAT)在阿默达巴德(印度),浦那(印度),加德满都(尼泊尔),和博卡拉(尼泊尔)。
    我们扩大了食品环境中的可持续发展领域,包括消费者到食品供应商的旅行,食品配送服务的存在,与可持续性相关的政策,供应商的食物浪费,供应商塑料使用,供应商实用程序使用情况,供应商回收和废物管理实践,食品包装。根据南亚4个城市的现有数据绘制框架,我们发现食物环境可持续性指标的变化,特别是关于消费者向食品摊贩的运输,送货服务的存在,和食物浪费。
    尽管大多数食品环境研究都集中在健康食品的可获得性和可负担性,迫切需要更好地了解食物环境的各个方面如何有助于实现环境目标。当将框架映射到现有的食物系统数据时,我们发现食品环境中环境可持续性的数据存在差距,并且不同环境中的指标存在差异.
    UNASSIGNED: Food environments, where people directly engage with broader food systems, may be an important contributor to the environmental sustainability of food systems.
    UNASSIGNED: The primary objectives of this study were to establish a new food environment framework that considers environmental indicators and to assess data availability and gaps using data previously collected as part of a food systems survey in 4 South Asian cities.
    UNASSIGNED: The framework was developed by conducting a structured literature review of previous food environment frameworks and in-depth interviews with content experts (n = 6). The framework and indicators were then mapped to data collected by consumer and vendor surveys using the Urban Food Systems Assessment Tool (UFSAT) in Ahmedabad (India), Pune (India), Kathmandu (Nepal), and Pokhara (Nepal).
    UNASSIGNED: We have expanded the sustainability domain within food environments to include consumer travel to food vendors, the presence of food delivery services, policies related to sustainability, vendor food waste, vendor plastic use, vendor utility usage, vendor recycling and waste management practices, and food packaging. Mapping the framework to existing data from 4 cities in South Asia, we found variations in food environment sustainability indicators, particularly regarding consumer transportation to food vendors, the presence of delivery services, and food waste.
    UNASSIGNED: Although the majority of food environment research focuses on the availability and affordability of healthy foods, there is an urgent need to understand better how aspects of food environments contribute to environmental goals. When mapping the framework to existing food systems data, we found gaps in data on environmental sustainability in food environments and variation in indicators across settings.
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