背景:光动力疗法是治疗某些形式的皮肤癌和广泛性日光性皮肤病的有效工具,并且可以有益于寻常痤疮的治疗。当用作区域治疗时,主要的限制因素之一是患者在治疗的照明阶段感到非常严重的灼痛。
目的:为了检查在大面积光动力疗法之前和期间应用的植物来源的抗伤害感生喷雾剂的有效性。
方法:面部分裂或左臂与右臂,我们对60例患者进行了安慰剂对照试验,以评估该喷雾剂减轻疼痛感觉的有效性.
结果:在照明阶段,所有照明点的疼痛都有统计学上的显着减轻,但在照明后的前72小时,不适水平没有显着差异。
结论:在研究期间仅进行大面积光动力疗法治疗。对于小面积治疗没有结论。
结论:使用简单的,植物来源的抗伤害性喷雾剂可以减少接受大面积光动力治疗的患者所经历的不适。
BACKGROUND: Photodynamic therapy is an effective tool in the management of some forms of skin cancer and generalized solar dermopathy and can be beneficial in the management of acne vulgaris. When used as an area treatment one of the main limiters is the quite severe burning pain that patients feel during the illumination phase of the treatment.
OBJECTIVE: To examine the effectiveness of a plant derived anti-nociceptive spray applied prior to and during large area photodynamic therapy.
METHODS: A split face or left arm versus right arm, placebo controlled trial was performed on 60 patients to assess the effectiveness of the spray in reducing pain perception.
RESULTS: There was a statistically significant reduction in pain at all illumination points during the illumination phase but no significant difference in discomfort levels in the first 72 h post illumination.
CONCLUSIONS: Only large area photodynamic therapy treatment was performed during the study. No conclusions can be drawn for small area treatments.
CONCLUSIONS: Use of a simple, plant derived anti-nociceptive spray can reduce the discomfort experienced by patients undergoing photodynamic therapy to large areas.