exposure rate

暴露率
  • 文章类型: Journal Article
    公园和游乐场的土壤是儿童接触有害物质的关键基质,因为它们的高暴露率。然而,在加纳对这个问题进行了最少的调查,因此需要进行这项研究。在2015年4月至2016年3月之间收集了120个土壤样品,然后使用原子吸收光谱法分析重金属。通过口腔生物可及性和危害指数评估了土壤中重金属对学童的健康风险。使用简单的生物可达性提取测试(SBET)方法估算金属的口腔生物可达性。铁(Fe)测得的总金属浓度最高范围为2785.0-15275.0mgkg-1,其次是Pb为2.1-284.0mgkg-1。金属的口腔生物可及性显着变化,铅和铜的最高平均值分别为47.80%和54.45%,分别。平均生物可及性结果的顺序与土壤中金属的平均浓度不一致。大多数重金属的危害指数(HI)表明,除铅以外,对儿童没有潜在的非致癌健康风险(HI<1)。加纳在2004年1月1日彻底禁止使用含铅燃料之前,长期使用含铅燃料以及铅在土壤介质中的持久性可能是其高风险的原因。铅对儿童的有害健康影响要求对游乐场采取和实施适当的环境管理,以减轻儿童对土壤重金属的暴露。
    Parks and playground soils constitute a critical matrix for children exposure to hazardous substances due to their high exposure rate. However, minimal investigation has been conducted in Ghana on the subject, thus the need for this research. One hundred and twenty (120) soil samples were collected between April 2015 and March 2016 and then analyzed for heavy metals using atomic absorption spectroscopy. The health risk posed to school children by the heavy metals laden in soil was assessed via oral bioaccessibility and hazard index. The oral bioaccessibility of the metals was estimated using the simple bioaccessibility extraction test (SBET) method. Iron (Fe) measured the highest range of total metal concentrations of 2785.0-15275.0 mg kg-1 followed by Pb of 2.1-284.0 mg kg-1. The oral bioaccessibility of the metals varied significantly with Pb and Cu exhibiting the highest mean values of 47.80% and 54.45%, respectively. The sequence for the mean bioaccessibility result does not correspond with the mean concentration of metals in the soil. The hazard index (HI) for most of the heavy metals indicated no potential non-carcinogenic health risk to children (HI < 1) except for Pb. The prolonged use of leaded fuel in Ghana prior to its outright ban on January 1 2004 and the persistence of Pb in soil media may account for its high risk. The deleterious health effects of Pb on children call for the adoption and implementation of appropriate environmental management of playgrounds so as to mitigate children\'s exposure to soil-laden heavy metals.
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  • 文章类型: Journal Article
    背景:医护人员为面临SARS-COV-2暴露风险升高的COVID-19患者执行各种临床程序。这项研究旨在评估Qazvin的医护人员暴露于COVID-19,2020年伊朗
    方法:我们在Qazvin省所有接触COVID-19的一线医护人员中进行了这项描述性分析研究。我们使用多阶段分层随机抽样方法将参与者输入研究。我们用了一份问卷,“COVID-19疾病背景下的卫生工作者暴露风险评估和管理”,由世界卫生组织(WHO)设计用于收集数据。我们使用SPSS软件版本24使用描述性和分析方法分析数据。
    结果:结果显示,研究中的所有参与者都职业暴露于COVID-19病毒。所以在243名医护人员中,186人(76.5%)处于低风险,57人(23.5%)处于COVID-19病毒感染的高风险。此外,从问卷中提到的六个领域中,卫生工作者在COVID-19疾病背景下的暴露风险评估和管理,医护人员与确诊的COVID-19患者互动类型领域的平均得分,对确诊的COVID-19患者进行的卫生工作者活动领域,在医疗保健互动期间坚持感染预防和控制(IPC)的领域,在高风险组中进行气溶胶生成程序时,对IPC的依从性高于低风险组。
    结论:尽管世卫组织有严格的指导方针,许多医护人员在感染COVID-19时都暴露在外。因此,医疗保健经理,规划者,政策制定者可以修改政策,提供适当和及时的个人防护设备,并计划对工作人员进行有关感染预防和控制原则的持续培训。
    BACKGROUND: Healthcare workers perform various clinical procedures for COVID-19 patients facing an elevated risk of exposure to SARS-COV-2.This study aimed to assess the healthcare workers\' exposure to COVID-19 in Qazvin, Iran in 2020.
    METHODS: We conducted this descriptive-analytical study among all healthcare workers on the frontline of exposure to COVID-19 in Qazvin province. We entered the participants into the study using a multi-stage stratified random sampling method. We utilized a questionnaire, \"Health workers exposure risk assessment and management in the context of COVID-19 disease\", designed by the World Health Organization (WHO) to collect data. We analyzed data using descriptive and analytical methods with SPSS software version 24.
    RESULTS: The results showed that all participants in the study had occupational exposure to the COVID-19 virus. So of 243 healthcare workers, 186 (76.5%) were at low risk and 57 (23.5%) at high risk of COVID-19 virus infection. Also, from the six domains mentioned in the questionnaire, health workers exposure risk assessment and management in the context of COVID-19 disease, the mean score of the domain of the type of healthcare worker interaction with a confirmed COVID-19 patient, the domain of health worker activities performed on a confirmed COVID-19 patient, the domain of the adherence to infection prevention and control (IPC) during health care interactions, and the domain of the adherence to IPC when performing aerosol-generating procedures in the high-risk group were more than the low-risk group.
    CONCLUSIONS: Despite strict WHO guidelines, many healthcare workers are exposed at contracting COVID-19. Therefore, healthcare managers, planners, and policymakers can revise the policies, provide appropriate and timely personal protective equipment, and plan for ongoing training for staff on the principles of infection prevention and control.
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  • 文章类型: Journal Article
    怀孕前和怀孕期间处方精神药物的趋势可能多年来有所改变,但是缺乏实际信息。因此,我们比较并评估了抗精神病药(锂)类别的暴露和接受率,抗焦虑药,镇静/催眠,抗抑郁药,在过去的二十年里,怀孕前和怀孕期间的精神兴奋剂。在IADB的妊娠子集中,从怀孕前六个月到孩子的出生日期,所有服用≥1种精神药物的单胎妊娠均被确定。nl处方数据库。精神药物的处方模式被区分为延续率(CR),起始速率(IR),停药率(DR),总暴露率(TER),和接受率。在怀孕前和怀孕期间暴露于精神药物的单胎妊娠在几十年之间从118.4增加到136.5(每1000单胎妊娠)。在第2十年中观察到了变化趋势,包括抗精神病药(3.3至6.8)和抗抑郁药(23.0至40.6)的TER高度增加。舍曲林的单个药物显着增加(TER:0.6至6.6和PAT:35.3%至82.5%),西酞普兰(TER:2.3至10.0和PAT:51.1%至74.6%),和喹硫平(TER:0.4至3.1,PAT:57.1%至66.0%)。尽管单胎妊娠中五类精神药物的总暴露率在第2十年中有所增加,但只有抗抑郁药类别在怀孕期间的接受率更高。某些SSRI抗抑郁药和非典型抗精神病药在第2十年中的处方频率高于第1十年,这反映出治疗方案是更安全的治疗选择。
    Trends in prescribing psychotropic drugs before and during pregnancy may have changed over the years, but actual information is lacking. We therefore compared and assessed the exposure and acceptance rates of classes of antipsychotic (+ lithium), anxiolytic, sedative/hypnotic, antidepressant, and psychostimulant before and during pregnancy in the past two decades. All singleton pregnancies with ≥1 prescription of psychotropic drug from six months before pregnancy until child\'s birthdate were identified in the pregnancy subset of the IADB.nl prescription database. The prescription patterns of psychotropics were distinguished as continuation rate (CR), initiation rate (IR), discontinuation rate (DR), total exposure rate (TER), and acceptance rate. Singleton pregnancies exposed to psychotropic drugs before and during pregnancy increased from 118.4 to 136.5 (per 1000 singleton pregnancies) between decades. Changing trends were observed in decade 2, including a high increase in the TER of antipsychotic class (3.3 to 6.8) and antidepressant class (23.0 to 40.6). A marked increase for individual drugs was seen for sertraline (TER: 0.6 to 6.6 and PAT: 35.3% to 82.5%), citalopram (TER: 2.3 to 10.0 and PAT: 51.1% to 74.6%), and quetiapine (TER: 0.4 to 3.1 and PAT: 57.1% to 66.0%). Although the total exposure rates of five classes of psychotropics in singleton pregnancies increased in decade 2, only antidepressant class had a higher acceptance rate during pregnancy. Certain SSRI antidepressants and atypical antipsychotics were more frequently prescribed in decade 2 than in decade 1, reflecting that treatment options were preferred for safer treatment choices.
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  • 文章类型: Journal Article
    已经建立了一种根据暴露量校准碘125种子的方法。标准的自由空气电离室,用于测量软X射线,被选择用于测量。使用四到六个种子的阵列来增强电离电流与背景电流的比率。在凹入室中单独测量来自阵列的种子。阵列的曝光速率与凹入室中的电离电流之和的商是凹入室的校准因子。为三种类型的碘-125种子建立了校准因子。种子暴露校准的总体不确定性小于6%。
    A method for calibrating iodine-125 seeds in terms of exposure has been established. The standard free-air ionization chamber, used for measuring soft x rays, was chosen for the measurements. Arrays of four to six seeds were used to enhance the ionization-current-to-background-current ratio. Seeds from an array were measured individually in a re-entrant chamber. The quotient of the exposure rate for the array by the sum of the ionization currents in the re-entrant chamber is the calibration factor for the re-entrant chamber. Calibration factors were established for three types of iodine-125 seeds. The overall uncertainty for the seed exposure calibrations is less than 6%.
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  • 文章类型: Journal Article
    这项研究涉及两个波兰地点的环境空气中存在的气态和颗粒结合汞的浓度,在排放结构方面不同,以及与这些汞物种相关的吸入风险估计。总气态汞(TGM)和PM2.5结合汞(PBM)的测量是在Zabrze的城市站和ZswotyPotok的农村站进行的,2014-2015年。这两个地点都位于西里西亚,被认为是欧洲空气污染热点之一。TGM在线测量(Tekran2537)。PM2.5样品是使用低容量采样器采集的。热分解后,通过CVAAS法测定PM中的Hg含量。Zabrze中TGM和PBM的中值浓度分别为2.48ngm-3和37.87pgm-3;同时在兹罗提波托克,分别为1.69ngm-3和27.82pgm-3。显然,观察到TGM和PBM浓度的季节性变化,反映了煤炭燃烧对电力和供暖用途的汞和PM排放的重要性。在最保守的暴露情况下,使用确定性方法进行健康风险评估。获得的HQ比率和累积HI指数低于极限值(<1)。这意味着吸入汞不太可能对健康造成危害。
    This study concerns the concentrations of gaseous and particle-bound mercury present in ambient air of two Polish sites, differing in terms of emission structure, and the estimation of inhalation risks related to those Hg species. The measurements of total gaseous mercury (TGM) and PM2.5-bound mercury (PBM) were performed at an urban station in Zabrze and a rural station in Złoty Potok, in 2014-2015. Both sites are located in Silesia, considered one of the European air pollution hot-spots. TGM was measured on-line (Tekran 2537). PM2.5 samples were taken with the use of low volume samplers. Hg contents in PM were determined by the CVAAS method following thermal decomposition. The median concentrations of TGM and PBM in Zabrze were 2.48 ng m-3 and 37.87 pg m-3, respectively; meanwhile in Zloty Potok, these were 1.69 ng m-3 and 27.82 pg m-3, respectively. Clearly, seasonal variability of TGM and PBM concentrations were observed, reflecting the importance of Hg and PM emissions from coal combustion for power and heating purposes. Health risk assessment was performed using a deterministic approach by the most conservative exposure scenario. The obtained HQ ratios and the cumulative HI indexes were below the limit value (<1). This means an unlikely health hazard due mercury inhalation.
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  • 文章类型: Journal Article
    137Cs γ-ray sources, which have been proposed by the Public Health Service as a substitute for radium in the treatment of malignant diseases, require suitable calibration if consistency is to be achieved in radiation treatment. Several 137Cs sources were calibrated using a graphite cavity ionization chamber in an open-air geometry. The contribution of scatter from the room surfaces was calculated and the source measurements corrected for this effect. A large-volume aluminum-walled ionization chamber was designed and fabricated for use in routine calibrations. This chamber will be used as a means for intercomparison of the source to be calibrated with one of the standards.
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  • 文章类型: Journal Article
    Mobile X-ray device is widely employed because it is useful for diagnosis in patients having mobility difficulties and in medical emergencies. As various devices for X-ray generation have continued to be developed, X-ray devices can now be used more safely and effectively. However, mobile X-ray devices generate relatively low X-ray doses due to the limitation of the power input. Therefore, the use of mobile X-ray devices is limited to thin parts of body. In this study, a new device was designed in order to increase the usefulness of mobile X-ray devices by offsetting the weaknesses of the existing mobile X-ray devices, rendering them useable independently. A supercapacitor and battery were used as the internal power source for the X-ray generation in the manufactured device. The pulse width modulation (PWM) method is applied to control the tube voltage and current required for generating the X-ray, and the pulse frequency modulation (PFM) method is applied to the control to generate the high voltage in order to enhance the precision and efficiency. The manufactured X-ray device was used to evaluate the control signal, frequency, and output characteristics according to changes in tube voltage and current. Based on the results of X-ray generation, it is confirmed that precise control was achieved by X-ray generation increases linearly with increasing tube voltage and tube current. This means that precise control of the manufactured mobile X-ray device is passible. In addition, the study confirmed that stable output was achieved by checking the tube voltage, tube current and exposure rate during the exposure times by high power condition.
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  • 文章类型: Journal Article
    A method for calibrating iodine-125 seeds in terms of exposure has been established. The standard free-air ionization chamber, used for measuring soft x rays, was chosen for the measurements. Arrays of four to six seeds were used to enhance the ionization-current-to-background-current ratio. Seeds from an array were measured individually in a re-entrant chamber. The quotient of the exposure rate for the array by the sum of the ionization currents in the re-entrant chamber is the calibration factor for the re-entrant chamber. Calibration factors were established for three types of iodine-125 seeds. The overall uncertainty for the seed exposure calibrations is less than 6%.
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  • 文章类型: Journal Article
    本文使用机载光谱伽马数据来估算北帕尔米群岛3区对人类的放射性危害程度,叙利亚中部。曝光率(ER),吸收剂量率(ADR),年有效剂量率(AEDR),计算了研究区域已建立的岩性评分图中包含的11个辐射单位的产热(HP),以评估辐射背景对人类的影响。获得的结果表明,区域3中的人体在长时间暴露的可接受范围内受到辐射危害。区域3中最高的辐射产热值对应于以铀和th值相对较高的磷酸盐位置。
    Airborne spectrometric gamma data are used in this paper to estimate the degree of radioactive hazard on humanity in Area-3, Northern Palmyrides, Central Syria. Exposure Rate (ER), Absorbed Dose Rate (ADR), Annual Effective Dose Rate (AEDR), and Heat Production (HP) of the eleven radiometric units included in the established lithological scored map in the study area have been computed to evaluate the radiation background influence in humans. The results obtained indicate that a human body in Area-3 is subjected to radiation hazards in the acceptable limits for long duration exposure. The highest radiogenetic heat production values in Area-3 correspond to the phosphatic locations characterized by relatively high values of uranium and thorium.
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  • 文章类型: Journal Article
    {010}-刻面暴露的锐钛矿TiO2晶体在暴露的刻面中表现出最高的光反应性。为了获得更高的暴露率,这项工作研究了纳米片的转变,该纳米片在由岩盐结构的Li2TiO3前体衍生的层内具有空腔。通过在HCl水溶液中的H/Li离子交换从前体中提取所有锂离子,四甲基铵离子嵌入后,前体可以分层成纳米片。在不同温度和pH值下对[TiO3]2-纳米片进行水热处理。结果表明,在较宽的pH和温度范围内形成锐钛矿相,与使用[Ti4O9]2-纳米带和[Ti1.73O4]1.07-纳米片相比。在低pH值,[111]多面纳米棒状锐钛矿纳米晶体优先形成,随着溶液pH值的增加,纳米晶体优先沿[001]方向生长,导致其表面上有很大比例的{010}面。光催化活性随着{010}晶面暴露率的增加而增加。
    {010}-Facet-exposed anatase TiO2 crystals exhibit the highest photoreactivity among the exposed facets. To obtain a higher exposure rate of this facet, the work investigated the transformation of the nanosheets with cavities within the layers derived from a rock-salt-structured Li2TiO3 precursor. All the lithium ions were extracted from the precursor by H+/Li+ ion exchange in HCl aqueous solutions, and after tetramethylammonium ions were intercalated, the precursor can delaminated into the nanosheets. The [TiO3]2- nanosheets were hydrothermally treated under different temperatures and pH values. The results showed that the anatase phase was formed in a wider range of pH and temperature, compared with using nanoribbons of [Ti4O9]2- and nanosheets of [Ti1.73O4]1.07-. At low pH, [111]-faceted nanorod-shaped anatase nanocrystals were formed preferentially, and the nanocrystals preferentially grow along the [001] direction with the increase of solution pH, leading to a large percentage of {010} facets on their surface. The photocatalytic activity increases with the increase of exposure rate of {010} facets.
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