excisional tissue biopsy

切除组织活检
  • 文章类型: Case Reports
    霍奇金淋巴瘤(HL)是一种通常起源于B细胞的恶性肿瘤。HL可以进一步分为经典HL和结节性淋巴细胞占优势的HL(NLPHL)。NLPHL是一种罕见的淋巴瘤。在胸部成像上,它通常在局部表现为明显的坚硬淋巴结肿大或纵隔肿块。有些患者可能有B症状(发烧,盗汗,和无意的减肥),脾肿大,还有肝肿大.我们描述了一名32岁男性的NLPHL病例,其经典发现是这种罕见的HL。
    Hodgkin\'s lymphoma (HL) is a malignancy that is typically B-cell in origin. HL can be further classified into classical HL and nodular lymphocyte-predominant HL (NLPHL). NLPHL is a rare lymphoma. It commonly presents locally with palpable firm lymphadenopathy or mediastinal mass seen on chest imaging. Some patients may have B symptoms (fever, night sweats, and unintentional weight loss), splenomegaly, and hepatomegaly. We describe a case of NLPHL in a 32-year-old male with classical findings of this rare class of HL.
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  • 文章类型: Case Reports
    口腔鳞状乳头状瘤(SP)是通常在舌头中生长的良性肿块,牙龈,小舌,嘴唇,和味觉。出现一例无症状的有蒂的鳞状乳头状瘤位于软腭中心。进行了手术治疗和组织病理学分析。本报告的目的是强调早期诊断和处理常见良性口腔病变以防止其转化为恶性肿瘤的重要性。
    Oral squamous papillomas (SPs) are benign masses commonly growing in the tongue, gingiva, uvula, lips, and palate. A case of an asymptomatic pedunculated squamous papilloma at the center of the soft palate is presented. Both surgical management and histopathologic analysis were conducted. The aim of this report is to stress the importance of early diagnosis and management of common benign oral lesions to prevent their transformation into malignancy.
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  • 文章类型: Case Reports
    COVID-19是由新型冠状病毒SARS-CoV-2引起的持续大流行。COVID-19的临床特征很多。虽然它是一种多系统疾病,它主要涉及呼吸系统。已有病例报道COVID-19的罕见表现,其中COVID-19相关的菊池病就是其中之一。据我们所知,这是世界上第三例报告的病例。我们报道了一位60多岁的女士患有COVID-19感染和继发性细菌性肺炎,这就需要入住ICU,有持续的发烧峰值,高炎症标记和白细胞减少。在患病的第三周,她还被发现有轻微的颈部淋巴结肿大,活检显示组织细胞坏死性淋巴结炎与菊池病一致。患者在没有任何干预的情况下在两周内恢复顺利。COVID-19相关菊池病的病理生理学尚不清楚。然而,COVID-19是一种病毒性疾病,涉及白细胞介素的变化。后者被假定为菊池病。
    COVID-19 is an ongoing pandemic caused by the novel coronavirus SARS-CoV-2. The clinical features of COVID-19 are myriad. Though it is a multisystem illness, it predominantly involves the respiratory system. There have been case reports on rare manifestations of COVID-19, of which COVID-19-related Kikuchi\'s disease is one of them. To our knowledge, this is the third reported case in the world. We report a lady in her late 60s with COVID-19 infection and secondary bacterial pneumonia, which necessitated ICU admission, having ongoing fever spikes with high inflammatory markers and leukopenia. She was also found to have tender cervical lymphadenopathy on the third week of illness, whose biopsy revealed histiocytic necrotizing lymphadenitis in keeping with Kikuchi\'s disease. The patient had an uneventful recovery in two weeks without any intervention. The pathophysiology of COVID-19-related Kikuchi\'s disease is unclear. However, COVID-19 is a viral illness that involves changes in interleukins. The latter is postulated in Kikuchi\'s disease.
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  • 文章类型: Case Reports
    本文的目的是介绍一名50岁女性的大型外周骨化性纤维瘤的临床病例,该病例是从先前诊断的化脓性肉芽肿演变而来的。该患者被转诊以治疗左上第一磨牙附近的颊和腭牙龈上的病变。颜色是紫红色,直径约3厘米,有一个光滑的表面,一个带蒂出血的底座,经过七年的进化,被诊断为化脓性肉芽肿.经过三年的逃避,患者返回报告病变增加和进食困难。临床上结节外观为小叶,粉红色的颜色和光滑,有蒂,公司的一致性,无出血,最大的延伸大约5厘米,延伸到上颌结节。切除病灶并进行组织病理学检查,这导致了周围骨化性纤维瘤的诊断。患者随访约18个月,修复,愈合满意,无复发临床征象。在这种情况下,观察到化脓性肉芽肿可能演变为周围骨化性纤维瘤,根据发生的组织病理学变化,随着钙化物质的发展,纤维成熟,三年后,初始病变的血管含量降低。
    The aim of the present article is to present the clinical case of a large peripheral ossifying fibroma that evolved from a previously diagnosed pyogenic granuloma in a 50-year-old woman. The patient was referred for treatment of a lesion over the buccal and palatal gingiva close to the left upper first molar. It was purplish-red in color, approximately 3 cm in diameter, having a smooth surface, a pedicled and bleeding base, with seven years of evolution, and diagnosed as pyogenic granuloma. After three years of evasion, the patient returned reporting an increase in the lesion and difficulty in eating. Clinically the nodule was lobular in appearance, pink in color and smooth, pediculated, firm in consistency, non-bleeding, about 5 cm in its greatest extension, extending to the maxillary tuberosity. The lesion was excised and referred for histopathological examination, which led to the diagnosis of peripheral ossifying fibroma. The patient was followed for approximately 18 months, prosthetically rehabilitated, with satisfactory healing and no clinical signs of recurrence. The possible evolution of a pyogenic granuloma to a peripheral ossifying fibroma was observed in this case, based on the histopathological changes that occurred, with the development of calcified material, fibrous maturation, and decreased vascular content of the initial lesion after three years.
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  • 文章类型: Case Reports
    We present a case of chondroblastoma-like chondroma (CLC) of soft tissue that manifested as a palmar mass on the left hand of an 84-year-old man. Physical examination, imaging investigation, and needle biopsy initially suggested a giant cell tumor of the tendon sheath, until a correct diagnosis was made based on excised specimen histology. The patient underwent a marginal excision for soft-tissue mass removal. Follow-up examination showed excellent relief of symptoms, and full hand mobility was regained. The diagnosis of CLC is challenging because the radiographic and pathological features vary. Therefore, we highly emphasize the importance of utilizing excisional tissue for histopathological assessment in atypical chondroma presentations.
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