Objective:To explore the clinical value of supine median³ nystagmus in the accurate diagnosis of horizontal semicircular canal benign paroxysmal positional vertigo（HC-BPPV）. Methods:A total of 187 patients with HC-BPPV admitted to the First Affiliated Hospital of Xi\'an Jiaotong University from June 2020 to March 2021 were selected. Among them 42 cases of Cupulolithiasis and 145 cases of Canalithiasis. The nystagmus parameters of patients left and right supine position and supine median³ position were recorded in detail by RART. According to the direction of supine median³ nystagmus, patients were divided into three groups: group A（nystagmus to weak side）, group B（nystagmus to strong side）, group C（negative nystagmus）. The canalith repositioning manoeuvres（CRM） was carried out by utility of an automatic vestibular function diagnosis and therapy system（SRM-IV）. The cure rate of CRM in three groups of HC-BPPV patients was compared, Multivariate logistic regression analysis was performed to analyze the influencing factors of CRM for HC-BPPV. Results:The cure rates of group A, group B and group C were 81.58%, 16.13% and 56.25%, respectively. The difference among the three groups was statistically significant. Then a pairwise comparison of group A, B and C, the difference was statistically significant（χ²A-B=40.294,P<0.001,χ²B-C=14.528, P<0.001,χ²A-C=11.606, P=0.001）; the results of multivariate logistic regression analysis showed that the direction of supine median³ nystagmus and BMI were the influencing factors of CRM for HC-BPPV. Conclusion:The direction, intensity and duration of supine median³ nystagmus play an important role in determining the responsibility semicircular canal of HC-BPPV.
目的：探讨仰卧正中位³眼震特征在水平半规管良性阵发性位置性眩晕（horizontal canal benign paroxysmal positional vertigo，HC-BPPV）责任半规管准确判定及疗效预估中的临床价值。 方法：选取2020年6月至2021年3月就诊于西安交通大学第一附属医院耳鼻咽喉头颈外科并确诊为HC-BPPV的患者187例，其中嵴顶结石症42例，管石症145例。采取快速轴位滚转试验（rapid axial roll test，RART）并详细记录患者在双耳下及仰卧正中位³引出的眼震参数，按照仰卧正中位³眼震方向分为3组：A组（眼震向弱侧）、B组（眼震向强侧）、C组（眼震阴性）。通过全自动前庭功能诊治系统（SRM-Ⅳ）进行复位治疗，比较3组HC-BPPV患者的复位治愈率，并进行多因素logistic回归分析HC-BPPV复位疗效的影响因素。 结果：A组治愈率81.58%（62/76），B组治愈率16.13%（5/31），C组治愈率56.25%（45/80），3组治愈率比较，差异有统计学意义（χ²=40.038，P<0.001），3组两两比较，患者治愈率差异均有统计学意义（χ²A-B=40.294，P<0.001，χ²B-C=14.528，P<0.001，χ²A-C=11.606，P=0.001）。多因素logistic回归分析结果显示：仰卧正中位³眼震方向及BMI是HC-BPPV复位疗效的影响因素。 结论：仰卧正中位³眼震的方向、强度及持续时间在判定HC-BPPV责任半规管中有重要意义。.

The study was conducted to develop a visual and intuitive quantitative evaluation method for maxillary cystic lesions after curettage. Mimics 16.0 and Geomagic Studio 2013 were used to form a precise reconstruction of the cystic lesion morphology of 60 cases; the average reduction rates and 95% confidence interval were calculated. Computed tomography (CT) registration was performed before and after surgery to observe morphology features of the bone regeneration of the cystic area. The average reduction rates (RR) of the cysts after curettage were (43.56 ± 16.79)%, (54.33 ± 17.15)% and (68.53 ± 15.99)% at 3 months, 6 months and 12 months after surgery, respectively. The average monthly reduction rates (MRR) were (12.07 ± 4.35)%, (8.16 ± 2.84)% and (5.35 ± 1.52)% at 3 months, 6 months and 12 months after surgery, respectively. Correlation analysis by comparing with each group showed that the effect of sex and age in the 3-month group and the initial size in the 12-month group on RR and MRR were statistically significant. Within the limitations of the study it seems that the chosen approach for quantitative evaluation of the therapeutic effect of curettage for jaw cystic lesions might facilitate visual and quantitative follow-up of cyst curettage and timely detection of recurrence.

BACKGROUND: The purpose of this study is to investigate the correlation between energy spectrum computed tomography (CT) imaging and the pathological characteristics and prognosis of cervical cancer.
METHODS: All participants underwent energy spectrum CT plain scan and enhanced scan of the cervix, uterine body, and common iliac vein. The correlation between the slope of energy spectrum attenuation curve and pathological characteristics and curative effect was analyzed, and the receiver operating characteristic (ROC) curve of the slope of energy spectrum attenuation curve to distinguish some pathological characteristics and curative effect was constructed.
RESULTS: The energy spectrum curves of cervix, uterine body, and common iliac vein all showed a downward trend. The slope of cervix energy spectrum curve showed a significant difference in different differentiation degree (P<0.05), and the slope of energy spectrum curve showed an upward trend. The slope of energy spectrum curve of common iliac vein was significantly different between high and low cell proliferation antigen marker (Ki67) (P<0.05), and the slope of Ki67 high expression was higher than that of Ki67 low expression. Treatment was effective in 17 participants and ineffective in 11. After treatment, the energy spectrum curve slope of cervix and energy spectrum curve slope of common iliac vein in the effective group were significantly increased compared with before treatment (P<0.05), and the energy spectrum curve slope of cervix in the ineffective group was increased compared with before treatment, but the difference was not significant (P>0.05). The area under the curve (AUC) of distinguishing Ki67 expression of energy spectrum curve slope of common iliac vein was 0.7008, sensitivity was 66.67%, and specificity was 62.34%. The AUC of distinguishing the curative effect of cervical energy spectrum curve slope was 0.6131, sensitivity was 56.25%, and specificity was 59.09%. The AUC of distinguishing the curative effect of energy spectrum curve slope of common iliac vein was 0.6563, sensitivity was 60.42%, and specificity was 58.33%.
CONCLUSIONS: The energy spectrum curve slope has potential value in the prediction of certain specific pathological types of cervical cancer and the evaluation of curative effect.

Small cell lung cancer belongs to neuroendocrine tumors and is the most malignant one in lung cancer. It possesses clinical features such as rapid growth, easy early metastasis, and poor prognosis. PET/CT is a molecular imaging technique that combines morphological and metabolic imaging. It has been widely used in the diagnosis, staging, treatment planning, efficacy and prognosis evaluation of tumors. This article reviews the efficacy, prognostic parameters, evaluation criteria, possible influencial factors, clinical application and value of 18F-fluorodeoxyglucose (18F-FDG) PET/CT in small cell lung cancer. The accuracy and sensitivity of 18F-FDG PET/CT in small cell lung cancer stage, efficacy and prognosis evaluation are significantly higher than those of traditional imaging methods. Maximal standardized uptake, metabolic tumor volume, and total lesion glycolysis have been applied in efficacy and prognosis prediction, which have important value in developing the personalized treatment and improving the survival for small cell lung cancer patient.
小细胞肺癌属于神经内分泌肿瘤，是肺癌中恶性程度最高的一种，具有生长快、易早期转移、预后差等临床特征。PET/CT是融形态与代谢显像于一体的分子影像技术，目前已被临床广泛应用于肿瘤的诊断、分期、治疗方案的制订、疗效及预后评估等方面。本文主要综述18F-氟代脱氧葡萄糖(18F-fluorodeoxyglucose，18F-FDG) PET/CT对小细胞肺癌疗效和预后的评价方法、评价参数、评价标准、影响因素、临床应用及其价值。18F-FDG PET/CT在小细胞肺癌的分期、疗效和预后评价上的准确度、灵敏度明显高于传统影像学方法，其主要的代谢参数最大标准摄取值、肿瘤代谢体积、病灶糖酵总量被应用到疗效与预后预测中，对制订小细胞肺癌患者的个性化治疗方案及改善生存有重要价值。.

OBJECTIVE: To investigate the changes of serum anti-schistosome antibody titers in schistosomiasis japonica patients after treatment, in order to provide the evidence for formulating the schistosomiasis surveillance program in marshland and lake regions.
METHODS: Upon prospective cohort study, the stool examination positive schistosomiasis patients and blood examination positive suspected patients (the titer was more than 1:80, including 1:80) were selected as the research objects in Jiangling County in 2014, and they received the 2-day praziquantel therapy. Half year, one year and two years after the treatment, their blood samples and fecal samples were collected for IHA anti-schistosome antibody detections and schistosome egg and miracidium detections.
RESULTS: In 2014, the stool examination positives were 251, and the majority of them were over 41 years old, accounting for 93.23% (234/251) ; 581 cases of high antibody titers were detected by the IHA method, and the majority of them were over 41 years old, accounting for 89.16% (518/581) . Half year, one year and two years after the treatment, among the stool examination positives, the negative conversion rates of stool positives were 99.60% (250/251), 100% (239/239) and 100% (234/234) respectively and the negative conversion rates of antibody positives were 21.91% (55/251), 64.11% (156/239) and 76.89% (193/234) respectively. In the high antibody titer positives, the negative conversion rates were 38.04% (221/581), 64.11% (359/560), and 77.86% (429/551) respectively, Half year, one year and two years after the treatment. There were statistically significant differences among the antibody negative conversion rates by χ2 test (χ2 = 77.538, 183.412, 25.469 respectively, all P < 0.001) . The geometric mean values of antibody titers of different durations between 2 groups were analyzed by 2-independent-samples T test, and the geometric mean values of antibody titers between the 2 groups were different before the treatment (t = 23.576, P < 0.01), but the geometric mean values of antibody titers between the 2 groups were not different 6 months, 1 year and 2 years after the treatment (t = -0.046, 1.165, -0.132, P = 0.964, 0.245, 0.895 respectively).
CONCLUSIONS: The levels of serum anti-schistosome antibody degrade slowly in schistosomiasis japonica patients after the treatment, and the results of IHA tests cannot distinguish the current schistosome infection from previous schistosome infection. Therefore, it is necessary to develop the specific diagnostic technology for schistosome infection in order to meet the need of monitoring.
［摘要］目的 分析人群日本血吸虫病治疗后抗体滴度变化, 为制订监测巩固方案提供科学依据。 方法 采用定群前 瞻性研究法, 以江陵县2014年检出的粪检阳性病人及血检阳性滴度1∶80以上 (含1∶80)者为对象, 先用吡喹酮2日疗法 治疗, 于治疗后半年、1年、2年分别采集血样、粪样, 进行IHA抗体检测和集卵孵化法检测。 结果 2014年粪检阳性病例 251人, 年龄以41岁以上为主, 占93.23% (234/251); IHA法检测抗体高滴度病例581人, 年龄以41岁以上为主, 占89.16% (518/581)。粪检阳性人群治疗后半年、1年、2年粪检转阴率分别为99.60% (250/251)、100% (239/239)、100% (234/234), IHA法检测抗体转阴率分别是21.91% (55/251)、64.11% (156/239)和76.89% (193/234); IHA法检测抗体高滴度人群治疗 后半年、1年、2年转阴率分别为38.04% (221/581)、64.11% (359/560)、77.86% (429/551); 抗体转阴率进行χ2 检验, 差异均 有统计学意义 (χ2 = 77.538、183.412、25.469, P 值均< 0.001)。分别对两组人群治疗前后不同时间段抗体滴度的几何均值 进行t 检验, 治疗前两组人群的抗体滴度几何均值差异有统计学意义 (t = 23.576, P < 0.01); 治疗后半年、1年、2年两组人 群抗体滴度的几何均值差异均无统计学意义 (t = -0.046、1.165、-0.132, P 均> 0.01)。 结论 日本血吸虫病治疗后人群血 清中抗体水平消退缓慢, 尚需开发特异的诊断技术以满足监测需求。.