背景:由于慢性肝病(CLD)和消化性溃疡疾病,埃及面临着巨大的公共卫生负担。CLD,主要由丙型肝炎病毒(HCV)感染引起,影响了全国2.9%以上的人口,区域差异。脂肪性肝病正在迅速成为CLD的重要贡献者,尤其是在城市地区。酸相关疾病是另一种广泛的疾病,可以显着影响生活质量。这些因素和其他因素显着影响在埃及进行的胃肠内镜手术的适应症和发现。
目的:我们旨在评估临床人口统计数据,适应症,以及在埃及各个地区接受胃肠内镜手术的埃及患者的内镜发现。
方法:本研究采用回顾性多中心横断面设计。数据是从埃及各省15个三级胃肠内窥镜检查单位接受胃肠内窥镜检查的患者中收集的。
结果:5910名年龄在38-63岁的患者被纳入研究;75%的患者接受了食管胃十二指肠镜检查(EGD),而25%的人接受了结肠镜检查。在所有被研究的患者中,最常见的EGD适应症是消化不良(19.5%),其次是呕血(19.06%),和黑便(17.07%)。招募患者的最终EGD诊断为门静脉高压相关后遗症(60.3%),其次是酸相关疾病(55%),而10.44%的患者进行了正常明显的内窥镜检查。男性,老年,和慢性肝病的存在是更常见的患者来自上埃及省下。便血(38.11%)是结肠镜检查的最多指征,其次是不明原因贫血(25.11%)。IBD和痔疮(22.34%和21.86%,分别)是被研究患者中最普遍的诊断,而其中18.21%的患者结肠镜检查结果正常。
结论:这是描述埃及内镜手术情况的最大研究。我们的研究强调了在埃及,疾病负担的区域差异对胃肠内窥镜检查的利用和结局的显著影响.慢性肝病的高患病率反映在EGD的研究结果中,而结肠镜检查结果提示有可能需要提高对结直肠疾病的认识.
BACKGROUND: Egypt faces a significant public health burden due to chronic liver diseases (CLD) and peptic ulcer disease. CLD, primarily caused by Hepatitis C virus (HCV) infection, affects over 2.9% of the population nationwide, with regional variations. Steatotic liver disease is rapidly emerging as a significant contributor to CLD, especially in urban areas. Acid-related disorders are another widespread condition that can significantly impact the quality of life. These factors and others significantly influence the indications and findings of gastrointestinal endoscopic procedures performed in Egypt.
OBJECTIVE: We aimed to evaluate the clinico-demographic data, indications, and endoscopic findings in Egyptian patients undergoing gastrointestinal endoscopic procedures in various regions of Egypt.
METHODS: This study employed a retrospective multicenter cross-sectional design. Data was collected from patients referred for gastrointestinal endoscopy across 15 tertiary gastrointestinal endoscopy units in various governorates throughout Egypt.
RESULTS: 5910 patients aged 38-63 were enrolled in the study; 75% underwent esophagogastroduodenoscopy (EGD), while 25% underwent a colonoscopy. In all studied patients, the most frequent indications for EGD were dyspepsia (19.5%), followed by hematemesis (19.06%), and melena (17.07%). The final EGD diagnoses for the recruited patients were portal hypertension-related sequelae (60.3%), followed by acid-related diseases (55%), while 10.44% of patients had a normally apparent endoscopy. Male gender, old age, and the presence of chronic liver diseases were more common in patients from upper than lower Egypt governorates. Hematochezia (38.11%) was the most reported indication for colonoscopy, followed by anemia of unknown origin (25.11%). IBD and hemorrhoids (22.34% and 21.86%, respectively) were the most prevalent diagnoses among studied patients, while normal colonoscopy findings were encountered in 18.21% of them.
CONCLUSIONS: This is the largest study describing the situation of endoscopic procedures in Egypt. our study highlights the significant impact of regional variations in disease burden on the utilization and outcomes of GI endoscopy in Egypt. The high prevalence of chronic liver disease is reflected in the EGD findings, while the colonoscopy results suggest a potential need for increased awareness of colorectal diseases.