epiphyses

附生
  • 文章类型: Case Reports
    小儿踝关节损伤是常见的;踝骨phy骨折在儿童中也很常见。但是孤立的腓骨远端骨腓骨远端骨折在临床上很少见。我们描述了一例青少年完全移位的Salter-HarrisII型腓骨远端骨phy骨折的不寻常病例。闭合还原的尝试失败,患者需要切开复位和内固定。局部骨膜和腓骨上支持带从腓骨远端干phy端撕脱,腓骨肌腱在下面露出,但没有明显的半脱位。据我们所知,这种组合的伤害以前没有报道过。
    Pediatric ankle injuries are common; ankle epiphyseal fractures are also common in children. But isolated distal epiphyseal fibular fractures of the distal fibula are clinically rare. We describe one unusual case of an adolescent with a completely displaced Salter-Harris type II distal fibular epiphyseal fracture. The attempt of closed reduction failed, and the patient required open reduction and internal fixation. The localized periosteum and the superior peroneal retinaculum were avulsed from the distal fibular metaphysis, with the peroneal tendons underneath exposed but no obvious subluxation. To the best of our knowledge, this combination of injuries has not been previously reported.
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  • 文章类型: Case Reports
    在以前的报告中,甲状腺功能减退,垂体功能减退,性腺功能减退是SCFE的常见内分泌原因,但这是第一次观察到先天性肾上腺增生。因此,接受长期内分泌治疗的先天性肾上腺增生患者可能面临更高的SCFE风险.
    In previous reports, hypothyroidism, hypopituitrism, and hypogonadism were common endocrine causes of SCFE, but this is the first time that congenital adrenal hyperplasia has been observed. As such, patients who have undergone long-term endocrine treatment for congenital adrenal hyperplasia could potentially be subjected to a higher risk for SCFE.
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  • 文章类型: Journal Article
    背景:儿童胫骨远端骨phy骨折常伴有关节面破坏。随着流离失所的增加,内固定通常使用骨phy螺钉进行,以闭合骨折间隙。尽管有限,高水平的临床证据支持植入物移除,骨phy螺钉通常在骨折愈合后被移除,因为胫骨关节上的接触力可能会增加。这项研究的目的是调查和比较儿童的结果和并发症,这些儿童接受了胫骨远端骨phy骨折的手术治疗,并放置了骨phy螺钉,并且在至少2年的术后随访中保留了植入物。
    方法:来自两个城市三级护理中心的18岁以下儿童接受了胫骨远端Salter-HarrisIII和IV骨折的手术治疗(2013-2020年)。人口统计,术中,术后,并收集射线照相数据。在最后的随访中收集使用足踝能力测量(FAAM)和单一评估数字评估(SANE)问卷的患者报告结果(PRO)。统计分析,包括功率分析,已执行。
    结果:包括52名儿童(30名男性,22名女性),受伤时平均年龄为13.3岁(范围,7.7-16.4年)。35名儿童保留了植入物;17名儿童移除了植入物。所有人都完成了FAAM问卷,平均随访时间为4.4±1.9年,29人完成了SANE问卷,平均随访4.4±1.7年。患者人口统计学无统计学差异,手术变量,或观察到PROs。六个孩子从最初的手术中经历了并发症,包括感染和复杂的区域疼痛综合征,两组间并发症发生率无差异(P=0.08)。此外,未观察到植入物移除导致的并发症.
    结论:与胫骨远端骨phy骨折固定和愈合后取出植入物的儿童相比,保留骨phy植入物的儿童具有相似的功能结局。
    方法:III级回顾性比较研究。
    BACKGROUND: Fractures of the distal tibial epiphysis in children are often accompanied by articular surface disruption. With increased displacement, internal fixation is frequently performed with an epiphyseal screw to close the fracture gap. Despite limited, high-level clinical evidence to support implant removal, epiphyseal screws are commonly removed after fracture healing due to potentially increased contact forces on the tibiotalar joint. The purpose of this study was to investigate and compare outcomes and complications in children that underwent surgical treatment of distal tibial epiphyseal fractures with placement of an epiphyseal screw(s) and had the implant(s) retained versus removed at a minimum of 2-year postoperative follow-up.
    METHODS: Children younger than 18 years from two urban tertiary care centers who underwent operative management of distal tibia Salter-Harris III and IV fractures using epiphyseal screws (2013-2020) were divided into two cohorts: retained epiphyseal screws and implant removed. Demographics, intraoperative, postoperative, and radiographic data were collected. Patient-reported outcomes (PROs) using the Foot and Ankle Ability Measure (FAAM) and Single Assessment Numeric Evaluation (SANE) questionnaires were collected at the final follow-up. Statistical analysis, including power analysis, was performed.
    RESULTS: Fifty-two children were included (30 males, 22 females) with a mean age of 13.3 years at the time of injury (range, 7.7-16.4 years). Thirty-five children retained the implants; seventeen had implants removed. All completed the FAAM questionnaires at a mean follow-up of 4.4 ± 1.9 years, while 29 completed the SANE questionnaire at a mean follow-up of 4.4 ± 1.7 years. No statistically significant difference in patient demographics, surgical variables, or PROs was observed. Six children experienced complications from the initial surgery, including infections and complex regional pain syndrome, with no difference in complication rates between the cohorts ( P =0.08). Furthermore, no complication was observed as a result of implant removal.
    CONCLUSIONS: Children with retained epiphyseal implants have similar functional outcomes as compared with those who had implants removed after distal tibial epiphyseal fracture fixation and union.
    METHODS: Level III-Retrospective comparative study.
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  • 文章类型: Journal Article
    2022年6月9日,张某(男)因涉嫌强制猥亵同学,于案发当时被依法刑事拘留。在审讯过程中,张某自报出生于2006年9月22日;户籍资料记载张某出生于2005年9月22日,男性,汉族,公民身份号码为******20050922****。为正确处理此案,某市公安局委托本鉴定机构对张某本次摄片时(2022年6月10日)的骨龄进行法医学鉴定。.
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  • 文章类型: Journal Article
    对第二次世界大战时期的26个岩骨和掌骨骨的骨p的比较分析显示,DNA产量或STR分型的成功率没有显着差异。岩骨之间DNA保存的意外均等,骨骼遗骸中内源性DNA的著名来源,和掌骨的骨phy,它们是多孔的,容易受到植物学变化的影响,令人惊讶。在这项研究中,我们引入ATR-FTIR光谱作为一种方法来揭示骨分子结构和DNA保存之间的相关性。对具有相同织物学历史的掌骨和岩骨进行采样并准备进行DNA分析。虽然一部分样本用于DNA分析,另一例接受了ATR-FTIR光谱检查.比较了掌骨骨和岩骨骨的归一化光谱和FTIR指数。因为使用的遗骸的纺织历史相对较短和稳定,ATR-FTIR光谱揭示了两种骨骼类型之间的细微结构差异。岩骨表现出更高的矿化,而附生含有更多的有机物。在掌骨骨phy中意外保存DNA可能归因于小梁内软组织残留物的存在。在这里观察到的骨骼分子结构的差异表明,有不同的机制可以在骨骼组织中保存DNA。
    A comparative analysis of 26 petrous bones and epiphyses of metacarpals from the Second World War era revealed no significant differences in DNA yield or success in STR typing. This unexpected parity in DNA preservation between the petrous bone, a renowned source of endogenous DNA in skeletal remains, and the epiphyses of metacarpals, which are porous and susceptible to taphonomic changes, is surprising. In this study, we introduced ATR-FTIR spectroscopy as an approach to unravel the correlation between bone molecular structure and DNA preservation. Metacarpals and petrous bones with same taphonomic history were sampled and prepared for DNA analyses. While one portion of the sample was used for DNA analysis, the other underwent ATR-FTIR spectroscopic examination. The normalized spectra and FTIR indices between the epiphyses of metacarpals and petrous bones were compared. Because the taphonomic history of the remains used is relatively short and stable, the ATR-FTIR spectroscopy unveiled subtle structural differences between the two bone types. Petrous bones exhibited higher mineralization, whereas epiphyses contained more organic matter. The unexpected preservation of DNA in the epiphyses of metacarpals can likely be attributed to the presence of soft tissue remnants within the trabeculae. Here observed differences in the molecular structure of bones indicate there are different mechanisms enabling DNA preservation in skeletal tissues.
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  • 文章类型: Journal Article
    背景和目的:骨龄测定是对不明遗骸进行法医和灾难鉴定的一种有价值的方法,以及医疗和外科手术目的。这项回顾性研究的目的是确定基于骨phy融合阶段的年龄,并调查与性别相关的差异。材料和方法:从约旦南部医院的医学影像中心收集膝盖的X射线,并由两名确定股骨闭合骨epi相的观察者进行检查,胫骨,和腓骨的末端靠近膝盖根据三阶段分类。结果:主要结果表明,与男性相比,女性在股骨下端以及胫骨和腓骨上端显示出较早的骨phy结合(II期)。在男性中,在17-18岁时,可以看到膝关节骨完全愈合的开始(第三阶段),而在女性中,它是在16-17岁的时候看到的。此外,在21-22岁和20-21岁的年龄组中,100%的男性和女性膝关节骨骼显示完全愈合,分别。尽管女性表现出比男性更早的骨phy完全结合的开始和结束,对收集到的数据进行分析显示,在膝关节骨的骨连接的三个阶段,男性和女性之间没有显着的年龄差异。结论:膝关节骨epi骨融合的影像学分析结果是确定实际年龄的有用方法。这项研究支持不同地理位置之间的性别和种族差异。需要大量样本的研究来验证我们的发现。
    Background and Objectives: Bone age determination is a valuable method for forensic and disaster identifications of unknown human remains, as well as for medical and surgical procedural purposes. This retrospective research study aimed to determine the age based on epiphyseal fusion stages and investigate differences related to gender. Materials and Methods: X-rays of the knee were collected from medical imaging centers in hospitals in the south of Jordan and examined by two observers who determined the bone epiphyseal phase of closure for the femur, tibia, and fibula bone ends close to the knee based on a three-stage classification. Results: The main results revealed that females showed earlier epiphyseal union (Stage II) at the lower end of the femur and the upper ends of the tibia and fibula compared to males. In males, the start of complete union (Stage III) at knee bones was seen at the age of 17-18 years, while in females, it was seen at the age of 16-17 years. Additionally, knee bones showed complete union in 100% of males and females in the age groups 21-22 years and 20-21 years, respectively. Although females showed an earlier start and end of epiphyseal complete union than males, analysis of collected data showed no significant age differences between males and females at the three stages of epiphyseal union of the knee bones. Conclusions: Findings of the radiographic analysis of bone epiphyseal fusion at the knee joint are a helpful method for chronological age determination. This study supports the gender and ethnicity variation among different geographical locations. Studies with a high sample number would be needed to validate our findings.
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    文章类型: Case Reports
    Epiphyseal fractures of the metatarsal head are a rare entity specially as an isolated injury and is rarely seen in patients with skeletal immaturity. Due lack of documentation for this type of fracture, the treatment of choice is uncertain. The purpose of the present study is to present two cases and treatment of epiphyseal fracture of the second metatarsal head, to our knowledge there are no publications for this injury.
    Las fracturas epifisarias de la cabeza metatarsiana son una entidad poco frecuente, principalmente cuando se presentan de forma aislada y en raras ocasiones se ven en pacientes con inmadurez esquelética. Debido a la escasez de documentación para este tipo de fractura, el tratamiento de elección es incierto. El motivo del presente estudio es presentar dos casos de fractura epifisaria de la cabeza del segundo metatarsiano y su tratamiento, ya que para nuestro conocimiento no hay publicaciones al respecto.
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  • 文章类型: Journal Article
    小儿踝关节骨折是常见的损伤,占所有周围密封损伤的重要部分。Salter-Harris分类是关于physeal和epi骨周围损伤的最流行的分类。Ogden对此进行了扩展,并描述了7型骨折,这些骨折完全是骨phy内骨折,包括骨折从关节表面通过骨phy软骨的传播,不涉及phy。这些损伤在患有旋后倒置型损伤的儿科患者的腓骨远端很常见。文献中没有关于这些损伤的治疗的具体指南或建议。我们介绍了这种损伤模式的三例,并描述了我们选择的管理方法,该方法可使每位患者达到完全,无痛的踝关节活动范围,并恢复到所有先前的活动和运动,没有并发症。旋后倒置型小儿踝关节骨折是所有整形外科医生在整个实践或训练中的某个时候都会遇到的常见损伤。识别骨折变异并了解小儿踝关节骨折的治疗方案对整个骨科社区很重要。
    Pediatric ankle fractures are prevalent injuries that make up a notable portion of all periphyseal injuries. The Salter-Harris classification is the most popular classification about physeal and periepiphyseal injuries. Ogden expanded on this and described type 7 fractures which are completely intraepiphyseal and include propagation of the fracture from the articular surface through the epiphyseal cartilage and do not involve the physis. These injuries are common about the distal fibula in pediatric patients with supination-inversion type injuries. There are no specific guidelines or recommendations on treatment of these injuries in the literature. We present three cases of this injury pattern and describe our chosen management that leads each patient to full, painless ankle range of motion and return to all prior activities and sports without complication. Supination-inversion type pediatric ankle fractures are common injuries that all orthopaedic surgeons will encounter at some point throughout their practice or training. Recognizing fracture variants and understanding treatment options of pediatric ankle fractures are important for the orthopaedic community as a whole.
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  • 文章类型: Journal Article
    这项研究旨在检查用eldecalcitol(ELD)进行卵巢切除的大鼠长骨的骨phy骨和干phy端之间的基于最小化的骨形成。将16周龄雌性大鼠分为四组:接受赋形剂的假手术大鼠(假手术组),接受媒介物的去卵巢(OVX)大鼠(媒介物组),或ELD(30或90纳克/千克体重,分别;ELD30和ELD90组)。ELD给药增加了骨体积和小梁厚度,减少OVX大鼠的骨phy和干mis端破骨细胞的数量。Sham和Vehicle组在两个区域中主要表现出基于重塑的骨形成。ELD组的骨phy显示出基于最小化的骨形成的频率明显高于基于重塑的骨形成。相比之下,与ELD30组相比,ELD90组的干干meta端表现出显著更多的基于最小化的骨形成.然而,在ELD90组中,基于最小模型的骨形成和基于重塑的骨形成之间没有显着差异。虽然小模型诱导的新骨含有很少的硬化蛋白免疫反应性骨细胞,潜在的预先存在的骨头有很多。ELD组的骨phy中,在小型骨诱导的骨中,硬化素阳性骨细胞的百分比显着降低,而在干mis端则没有降低。因此,似乎ELD可能会在骨phy中而不是在干phy端中诱导基于最小化的骨形成,并且ELD驱动的最小化可能与硬化素合成的抑制有关。
    This study aimed to examine minimodeling-based bone formation between the epiphyses and metaphyses of the long bones of eldecalcitol (ELD)-administered ovariectomized rats. Sixteen-week-old female rats were divided into four groups: sham-operated rats receiving vehicle (Sham group), ovariectomized (OVX) rats receiving vehicle (Vehicle group), or ELDs (30 or 90 ng/kg BW, respectively; ELD30 and ELD90 groups). ELD administration increased bone volume and trabecular thickness, reducing the number of osteoclasts in both the epiphyses and metaphyses of OVX rats. The Sham and Vehicle groups exhibited mainly remodeling-based bone formation in both regions. The epiphyses of the ELD groups showed a significantly higher frequency of minimodeling-based bone formation than remodeling-based bone formation. In contrast, the metaphyses exhibited significantly more minimodeling-based bone formation in the ELD90 group compared with the ELD30 group. However, there was no significant difference between minimodeling-based bone formation and remodeling-based bone formation in the ELD90 group. While the minimodeling-induced new bone contained few sclerostin-immunoreactive osteocytes, the underlying pre-existing bone harbored many. The percentage of sclerostin-positive osteocytes was significantly reduced in the minimodeling-induced bone in the epiphyses but not in the metaphyses of the ELD groups. Thus, it seems likely that ELD could induce minimodeling-based bone formation in the epiphyses rather than in the metaphyses, and that ELD-driven minimodeling may be associated with the inhibition of sclerostin synthesis.
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  • 文章类型: Journal Article
    方法:一名13岁的青少年男孩患有偏瘫性脑瘫,尽管进行了广泛的保守治疗,但膝关节屈曲畸形为10°。由于胫骨后斜度(PTS)为16°,胫骨近端应用前半表皮固定术。9个月后取出2个螺钉。16个月的最后随访显示膝关节完全伸展,PTS为4°。
    结论:所提出的技术是治疗膝关节屈曲畸形并增加PTS的良好替代方法,令人惊讶的是文献中没有描述。对于其他病理,例如小儿前交叉韧带损伤伴PTS增加,这可能值得考虑。
    METHODS: A 13-year-old adolescent boy with hemiplegic cerebral palsy suffering from fixed knee flexion deformity of 10° despite extensive conservative treatment. Owing to a posterior tibial slope (PTS) of 16°, anterior hemiepiphysiodesis was applied to the proximal tibia. The 2 screws were removed after 9 months. Final follow-up at 16 months showed complete knee extension and a PTS of 4°.
    CONCLUSIONS: The presented technique is a good alternative in knee flexion deformity with an increased PTS and has surprisingly not been described in the literature. This might be worth considering for other pathologies such as pediatric anterior cruciate ligament injury with an increased PTS.
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