■对嗜酸性粒细胞性胃肠道疾病(EGID)患者的人口统计学特征了解甚少。基于人群的EGID人口统计学评估可能表明诊断中的健康差异。
■我们旨在表征EGID的人口统计学分布,并评估在报告患者特征时可能存在的偏倚。
■我们进行了系统评价,提取年龄数据,性别,性别,种族,种族,身体质量指数,保险,EGID患者和来源人群的城市/农村居住地。通过卡方检验评估比例差异。人口报告与最近的指南进行了比较。
■在符合纳入/排除标准的50项研究中,12例报告EGID和来源人群中≥1个人口统计学特征。除了年龄、性别或性别,人口统计学很少描述(种族=4,种族=1,保险=1)或没有描述(体重指数,城市/农村住宅)。相对于来源人群,男性受试者的EoE或食管嗜酸性粒细胞增多比例更高,但其他EGID在性别或性别分布上无差异.“性别”和“性别”互换使用,经常只报告男性比例。种族和族裔的报告与指南不一致。
■当前数据仅支持EoE的男性优势。证据不足以支持任何特定种族的EGID丰富,民族,或其他人口群体。需要以人口为基础的研究,介绍病例和来源人群的人口统计数据。实施更具包容性的人口统计学特征报告指南对于防止EGID患者的及时诊断和管理差异至关重要。
UNASSIGNED: The demographic characteristics of patients with eosinophilic gastrointestinal diseases (EGIDs) are poorly understood. Population-based assessments of EGID demographics may indicate health disparities in diagnosis.
UNASSIGNED: We aimed to characterize the demographic distribution of EGIDs and evaluate the potential for bias in reporting patient characteristics.
UNASSIGNED: We conducted a systematic review, extracting data on age, sex, gender, race, ethnicity, body mass index, insurance, and urban/rural residence on EGID patients and the source population. Differences in proportions were assessed by chi-square tests. Demographic reporting was compared to recent guidelines.
UNASSIGNED: Among 50 studies that met inclusion/exclusion criteria, 12 reported ≥1 demographic feature in both EGID and source populations. Except for age and sex or gender, demographics were rarely described (race = 4, ethnicity = 1, insurance = 1) or were not described (body mass index, urban/rural residence). A higher proportion of male subjects was observed for EoE or esophageal eosinophilia relative to the source population, but no difference in gender or sex distribution was observed for other EGIDs. \"Sex\" and \"gender\" were used interchangeably, and frequently only the male proportion was reported. Reporting of race and ethnicity was inconsistent with guidelines.
UNASSIGNED: Current data support a male predominance for EoE only. Evidence was insufficient to support enrichment of EGIDs in any particular racial, ethnic, or other demographic group. Population-based studies presenting demographics on both cases and source populations are needed. Implementation of guidelines for more inclusive reporting of demographic characteristics is crucial to prevent disparities in timely diagnosis and management of patients with EGIDs.