BACKGROUND: Cancer pathology shows disease development and associated molecular features. It provides extensive phenotypic information that is cancer-predictive and has potential implications for planning treatment. Based on the exceptional performance of computational approaches in the field of digital pathogenic, the use of rich phenotypic information in digital pathology images has enabled us to identify low-level gliomas (LGG) from high-grade gliomas (HGG). Because the differences between the textures are so slight, utilizing just one feature or a small number of features produces poor categorization results.
METHODS: In this work, multiple feature extraction methods that can extract distinct features from the texture of histopathology image data are used to compare the classification outcomes. The successful feature extraction algorithms GLCM, LBP, multi-LBGLCM, GLRLM, color moment features, and RSHD have been chosen in this paper. LBP and GLCM algorithms are combined to create LBGLCM. The LBGLCM feature extraction approach is extended in this study to multiple scales using an image pyramid, which is defined by sampling the image both in space and scale. The preprocessing stage is first used to enhance the contrast of the images and remove noise and illumination effects. The feature extraction stage is then carried out to extract several important features (texture and color) from histopathology images. Third, the feature fusion and reduction step is put into practice to decrease the number of features that are processed, reducing the computation time of the suggested system. The classification stage is created at the end to categorize various brain cancer grades. We performed our analysis on the 821 whole-slide pathology images from glioma patients in the Cancer Genome Atlas (TCGA) dataset. Two types of brain cancer are included in the dataset: GBM and LGG (grades II and III). 506 GBM images and 315 LGG images are included in our analysis, guaranteeing representation of various tumor grades and histopathological features.
RESULTS: The fusion of textural and color characteristics was validated in the glioma patients using the 10-fold cross-validation technique with an accuracy equals to 95.8%, sensitivity equals to 96.4%, DSC equals to 96.7%, and specificity equals to 97.1%. The combination of the color and texture characteristics produced significantly better accuracy, which supported their synergistic significance in the predictive model. The result indicates that the textural characteristics can be an objective, accurate, and comprehensive glioma prediction when paired with conventional imagery.
CONCLUSIONS: The results outperform current approaches for identifying LGG from HGG and provide competitive performance in classifying four categories of glioma in the literature. The proposed model can help stratify patients in clinical studies, choose patients for targeted therapy, and customize specific treatment schedules.

We present a deep learning (DL) network-based approach for detecting and semantically segmenting two specific types of tuberculosis (TB) lesions in chest X-ray (CXR) images. In the proposed method, we use a basic U-Net model and its enhanced versions to detect, classify, and segment TB lesions in CXR images. The model architectures used in this study are U-Net, Attention U-Net, U-Net++, Attention U-Net++, and pyramid spatial pooling (PSP) Attention U-Net++, which are optimized and compared based on the test results of each model to find the best parameters. Finally, we use four ensemble approaches which combine the top five models to further improve lesion classification and segmentation results. In the training stage, we use data augmentation and preprocessing methods to increase the number and strength of lesion features in CXR images, respectively. Our dataset consists of 110 training, 14 validation, and 98 test images. The experimental results show that the proposed ensemble model achieves a maximum mean intersection-over-union (MIoU) of 0.70, a mean precision rate of 0.88, a mean recall rate of 0.75, a mean F1-score of 0.81, and an accuracy of 1.0, which are all better than those of only using a single-network model. The proposed method can be used by clinicians as a diagnostic tool assisting in the examination of TB lesions in CXR images.

UNASSIGNED: The study explores the use of Electroencephalograph (EEG) signals as a means to uncover various states of the human brain, with a specific focus on emotion classification. Despite the potential of EEG signals in this domain, existing methods face challenges. Features extracted from EEG signals may not accurately represent an individual\'s emotional patterns due to interference from time-varying factors and noise. Additionally, higher-level cognitive factors, such as personality, mood, and past experiences, further complicate emotion recognition. The dynamic nature of EEG data in terms of time series introduces variability in feature distribution and interclass discrimination across different time stages.
UNASSIGNED: To address these challenges, the paper proposes a novel adaptive ensemble classification method. The study introduces a new method for providing emotional stimuli, categorizing them into three groups (sadness, neutral, and happiness) based on their valence-arousal (VA) scores. The experiment involved 60 participants aged 19-30 years, and the proposed method aimed to mitigate the limitations associated with conventional classifiers.
UNASSIGNED: The results demonstrate a significant improvement in the performance of emotion classifiers compared to conventional methods. The classification accuracy achieved by the proposed adaptive ensemble classification method is reported at 87.96%. This suggests a promising advancement in the ability to accurately classify emotions using EEG signals, overcoming the limitations outlined in the introduction.
UNASSIGNED: In conclusion, the paper introduces an innovative approach to emotion classification based on EEG signals, addressing key challenges associated with existing methods. By employing a new adaptive ensemble classification method and refining the process of providing emotional stimuli, the study achieves a noteworthy improvement in classification accuracy. This advancement is crucial for enhancing our understanding of the complexities of emotion recognition through EEG signals, paving the way for more effective applications in fields such as neuroinformatics and affective computing.

In the realm of healthcare, the demand for swift and precise diagnostic tools has been steadily increasing. This study delves into a comprehensive performance analysis of three pre-trained convolutional neural network (CNN) architectures: ResNet50, DenseNet121, and Inception-ResNet-v2. To ensure the broad applicability of our approach, we curated a large-scale dataset comprising a diverse collection of chest X-ray images, that included both positive and negative cases of COVID-19. The models\' performance was evaluated using separate datasets for internal validation (from the same source as the training images) and external validation (from different sources). Our examination uncovered a significant drop in network efficacy, registering a 10.66% reduction for ResNet50, a 36.33% decline for DenseNet121, and a 19.55% decrease for Inception-ResNet-v2 in terms of accuracy. Best results were obtained with DenseNet121 achieving the highest accuracy at 96.71% in internal validation and Inception-ResNet-v2 attaining 76.70% accuracy in external validation. Furthermore, we introduced a model ensemble approach aimed at improving network performance when making inferences on images from diverse sources beyond their training data. The proposed method uses uncertainty-based weighting by calculating the entropy in order to assign appropriate weights to the outputs of each network. Our results showcase the effectiveness of the ensemble method in enhancing accuracy up to 97.38% for internal validation and 81.18% for external validation, while maintaining a balanced ability to detect both positive and negative cases.

UNASSIGNED: Artificial intelligence technologies have great potential in classifying neurodegenerative diseases such as Alzheimer\'s and Parkinson\'s. These technologies can aid in early diagnosis, enhance classification accuracy, and improve patient access to appropriate treatments. For this purpose, we focused on AI-based auto-diagnosis of Alzheimer\'s disease, Parkinson\'s disease, and healthy MRI images.
UNASSIGNED: In the current study, a deep hybrid network based on an ensemble classifier and convolutional neural network was designed. First, a very deep super-resolution neural network was adapted to improve the resolution of MRI images. Low and high-level features were extracted from the images processed with the hybrid deep convolutional neural network. Finally, these deep features are given as input to the k-nearest neighbor (KNN)-based random subspace ensemble classifier.
UNASSIGNED: A 3-class dataset containing publicly available MRI images was utilized to test the proposed architecture. In experimental works, the proposed model produced 99.11% accuracy, 98.75% sensitivity, 99.54% specificity, 98.65% precision, and 98.70% F1-score performance values. The results indicate that our AI system has the potential to provide valuable diagnostic assistance in clinical settings.

BACKGROUND: Advances in technology have led to the emergence of computerized diagnostic systems as intelligent medical assistants. Machine learning approaches cannot replace professional humans, but they can change the treatment of diseases such as cancer and be used as medical assistants.
BACKGROUND: Breast cancer treatment can be very effective, especially when the disease is detected in the early stages. Feature selection and classification are common data mining techniques in machine learning that can provide breast cancer diagnosis with high speed, low cost and high precision.
METHODS: This paper proposes a new intelligent approach using an integrated filter-evolutionary search-based feature selection and an optimized ensemble classifier for breast cancer diagnosis. The selected features mainly relate to the viable solution as the selected features are successfully used in the breast cancer disease classification process. The proposed feature selection method selects the most informative features from the original feature set by integrating adaptive thresholder information gain-based feature selection and evolutionary gravity-search-based feature selection. Meanwhile, classification model is done by proposing a new intelligent multi-layer perceptron neural network-based ensemble classifier.
RESULTS: The simulation results show that the proposed method provides better performance compared to the state-of-the-art algorithms in terms of various criteria such as accuracy, sensitivity and specificity. Specifically, the proposed method achieves an average accuracy of 99.42% on WBCD, WDBC and WPBC datasets from Wisconsin database with only 56.7% of features.
CONCLUSIONS: Systems based on intelligent medical assistants configured with machine learning approaches are an important step toward helping doctors to detect breast cancer early.

BACKGROUND: Epidemiological studies show that breast cancer is the most common cancer in women in the world. Breast cancer treatment can be very effective, especially when the disease is detected in the early stages. The goal can be achieved by using large-scale breast cancer data with the machine learning models METHODS: This paper proposes a new intelligent approach using an optimized ensemble classifier for breast cancer diagnosis. The classification is done by proposing a new intelligent Group Method of Data Handling (GMDH) neural network-based ensemble classifier. This method improves the performance of the machine learning technique by using a Teaching-Learning-Based Optimization (TLBO) algorithm to optimize the hyperparameters of the classifier. Meanwhile, we use TLBO as an evolutionary method to address the problem of appropriate feature selection in breast cancer data.
RESULTS: The simulation results show that the proposed method has a better accuracy between 7 and 26% compared to the best results of the existing equivalent algorithms.
CONCLUSIONS: According to the obtained results, we suggest the proposed algorithm as an intelligent medical assistant system for breast cancer diagnosis.

An automated diagnosis system is crucial for helping radiologists identify brain abnormalities efficiently. The convolutional neural network (CNN) algorithm of deep learning has the advantage of automated feature extraction beneficial for an automated diagnosis system. However, several challenges in the CNN-based classifiers of medical images, such as a lack of labeled data and class imbalance problems, can significantly hinder the performance. Meanwhile, the expertise of multiple clinicians may be required to achieve accurate diagnoses, which can be reflected in the use of multiple algorithms. In this paper, we present Deep-Stacked CNN, a deep heterogeneous model based on stacked generalization to harness the advantages of different CNN-based classifiers. The model aims to improve robustness in the task of multi-class brain disease classification when we have no opportunity to train single CNNs on sufficient data. We propose two levels of learning processes to obtain the desired model. At the first level, different pre-trained CNNs fine-tuned via transfer learning will be selected as the base classifiers through several procedures. Each base classifier has a unique expert-like character, which provides diversity to the diagnosis outcomes. At the second level, the base classifiers are stacked together through neural network, representing the meta-learner that best combines their outputs and generates the final prediction. The proposed Deep-Stacked CNN obtained an accuracy of 99.14% when evaluated on the untouched dataset. This model shows its superiority over existing methods in the same domain. It also requires fewer parameters and computations while maintaining outstanding performance.

In this paper, we propose a novel multi-stream video classifier for infant needs detection. The proposed system is an ensemble-based system that combines several machine learning to improve the overall result of the state-of-the-art algorithms. It is a multi-stream in the sense that it combines the output predictions of both audio and images of infants from every single classifier employed in the system for a unified result. This produces better performance and results compared to the previous other research techniques, which relied on only one of these modalities. For training and testing the proposed system, from the Dunstan Baby Language video collection, we built three separate datasets for videos, images, and sounds encompassing the five primary infant needs that require predicting. These are: hunger, have wind, uncomfortable (require diaper change), wants to burp or tired, with a total of 3348 samples. We used four different ensemble algorithms for the best reachable performance. The proposed algorithm improves the overall accuracies of each single classifier from a low of 51% to a high of 99%. The proposed method also improves the accuracy of the classification process by about 9% compared to the state-of-the-art approaches, which was 90%.

BACKGROUND: Feature selection in the face of high-dimensional data can reduce overfitting and learning time, and at the same time improve the accuracy and efficiency of the system. Since there are many irrelevant and redundant features in breast cancer diagnosis, removing such features leads to more accurate prediction and reduced decision time when dealing with large-scale data. Meanwhile, ensemble classifiers are powerful techniques to improve the prediction performance of classification models, where several individual classifier models are combined to achieve higher accuracy.
METHODS: In this paper, an ensemble classifier algorithm based on multilayer perceptron neural network is proposed for the classification task, in which the parameters (e.g., number of hidden layers, number of neurons in each hidden layer, and weights of links) are adjusted based on an evolutionary approach. Meanwhile, this paper uses a hybrid dimensionality reduction technique based on principal component analysis and information gain to address this problem.
RESULTS: The effectiveness of the proposed algorithm was evaluated based on the Wisconsin breast cancer database. In particular, the proposed algorithm provides an average of 17% better accuracy compared to the best results obtained from the existing state-of-the-art methods.
CONCLUSIONS: Experimental results show that the proposed algorithm can be used as an intelligent medical assistant system for breast cancer diagnosis.