■术后咽喉痛(POST)是气管粘膜损伤引起的气管插管全身麻醉后的常见并发症。多种技术可预防术后咽喉痛(POST)。我们的研究旨在比较两种技术:静脉注射利多卡因和口服利多卡因与安慰剂,以预防经气管插管全身麻醉后的术后咽喉痛。
■我们进行了前瞻性双盲,涉及患者的随机对照临床试验,建议在气管插管的全身麻醉下进行少于240分钟的计划手术。患者分为三组:L组:输注生理盐水,袖口充满碱化利多卡因。S组:注入1.5mg/kg利多卡因,袖口充满盐水。T组:安慰剂:输注生理盐水,袖口充满盐水。我们的主要结果是喉咙痛的发生率及其在术后前24小时的(视觉模拟量表)VAS评分。我们的次要结果是咳嗽的发生率,发音困难,吞咽困难,术后恶心呕吐。对
■90例患者进行分析,并分为3组,每组30例。术后第六个小时POST的发生率,对于安慰剂,“L”组,和“S”组,分别,67%,30%,和47%。在术后24小时,67%,13%,和37%。静脉注射利多卡因在第24小时显着降低了POST的VAS(S:6.80±20.70;T:20.67±18.182;p=0.02)。碱化利多卡因显著降低术后第6小时(L:8.17±22.761;T:23±21.838;p=0.048)和术后第24小时(L:6.33±20.592;T:20.67±18.182;p=0.019)的术后VAS,疼痛评分最低。术后6、24小时L、S组之间无统计学差别。两种利多卡因技术都能在出现时减少咳嗽,具有碱化利多卡因的优越性(p=0.02)。他们降低了咳嗽的发生率,发音困难,吞咽困难,恶心,和安慰剂相比呕吐。
■静脉注射利多卡因可以更好地控制术后咽喉痛。
UNASSIGNED: postoperative sore throat (POST) is a common complication after general anesthesia with endotracheal intubation caused by tracheal mucosal injury. Multiple techniques prevent postoperative sore throat (POST). Our study aimed to compare two techniques: intravenous and intracuff lidocaine versus placebo to prevent postoperative sore throat after general anesthesia with orotracheal intubation.
UNASSIGNED: we conducted a prospective double-blind, randomized controlled clinical trial involving patients, proposed for a scheduled surgery less than 240 minutes under general anesthesia with orotracheal intubation. Patients were divided into three groups: L group: infused with saline, cuff filled with alkalinized lidocaine. S group: Infused with 1.5 mg/kg of lidocaine, cuff filled with saline. T group: placebo: infused with saline, cuff filled with saline. Our primary outcome was the incidence of sore throat and their (visual analog scale) VAS score in the first 24 postoperative hours. Our secondary outcomes were the incidence of cough, dysphonia, dysphagia, and postoperative nausea and vomiting.
UNASSIGNED: ninety patients were analyzed and divided into 3 groups of 30. The incidence of POST at the sixth postoperative hour, for placebo, the \"L\" group, and the \"S\" group, respectively, was 67%, 30%, and 47%. And at the 24th postoperative hours 67%, 13%, and 37%. Intravenous lidocaine reduced significantly the VAS of POST at the 24th hour (S: 6.80 ± 20.70; T: 20.67 ± 18.182; p= 0.02). Alkalinized lidocaine decreased significantly the VAS of POST in the sixth (L: 8.17 ± 22.761; T: 23 ± 21.838; p = 0.048) and the 24th postoperative hour (L: 6.33 ± 20.592; T: 20.67 ± 18.182; p= 0.019) with the lowest pain score. There was no statistically significant difference between the L and S groups at the 6 and 24 postoperative hours. Both lidocaine techniques reduced cough at emergence, with the superiority of alkalinized lidocaine (p=0.02). They decreased the incidence of cough, dysphonia, dysphagia, nausea, and vomiting compared to a placebo.
UNASSIGNED: intravenous and intracuff lidocaine allowed better control of postoperative sore throat.