enchondroma

内生软骨瘤
  • 文章类型: Case Reports
    在这里,我们报道了一位38岁的健康女士的不寻常表现,她的左前臂远端掌侧有一个无痛的缓慢生长的病变,到达鱼际区域超过15年。病变的磁共振成像显示,在T1和T2加权图像中,多小叶软组织肿块具有低信号和高信号,并具有均匀的对比增强。此外,在第一掌骨中发现稳定的色素性骨性病变,显示低T1和高T2信号,并伴有外周增强。组织病理学检查与圆柱瘤和内生软骨瘤一致,分别。患者在1年的随访中完全康复,没有复发。内生软骨瘤是手部最常见的良性肿瘤,散发性真皮圆柱瘤,相比之下,很少影响上肢。以前没有报道过这两种病理实体的共存,这可能会使诊断复杂化。
    Herein, we report an unusual presentation of a 38-year-old heathy lady with a painless slowly growing lesion in the volar aspect of her left distal forearm reaching the thenar area for >15 years. Magnetic resonance imaging of the lesion showed multilobulated soft tissue mass with low and high signal in T1- and T2-weighted images with homogenous contrast enhancement. Additionally, a stable serpiginous bony lesion was noted in the first metacarpal bone showing low T1 and high T2 signals with peripheral enhancement. Histopathological examination was consistent with cylindroma and enchondroma, respectively. The patient had full recovery with no recurrence at a 1-year follow-up visit. While enchondroma is the most common benign tumor of the hand, sporadic dermal cylindroma, in contrast, rarely affects the upper extremity. The coexistence of these two pathological entities was not previously reported and it may complicate the diagnosis.
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  • 文章类型: Case Reports
    软骨瘤是一种骨软骨良性肿瘤,最常见的累及手脚的管状骨。据我们所知,三角骨和针状骨是腕骨,文献中尚未报道三角骨和针状骨的内软骨瘤。
    一名26岁的男性出现右手腕肿胀和疼痛的末端运动。根据磁共振成像结果,诊断为三七和梨状内生软骨瘤。进行骨切除和刮宫,组织病理学证实了诊断.经过2年的随访,患者在切除后获得了无痛的手腕运动,也没有复发的迹象.改良的梅奥手腕评分为75分(一般)提高到100分(优秀)。
    外科医生应始终牢记罕见部位肿瘤的可能性,并借助成像方式和活检准确诊断肿瘤。
    UNASSIGNED: Enchondroma is a cartilaginous benign tumor of bone with the most common involvement of tubular bones of hands and feet. The triquetrum and pisiform are carpal bones and the enchondroma of the triquetrum and pisiform has not been reported in the literature to the best of our knowledge.
    UNASSIGNED: A 26-year-old male presented with swelling over his right wrist with painful terminal motion. Based on magnetic resonance imaging findings, diagnosis of enchondroma of triquetrum and pisiform was made. Bone excision and curettage were performed, and histopathology confirmed the diagnosis. After 2 years of follow-up, the patient has gained pain-free wrist movements post excision, and there are no signs of recurrence. The Modified Mayo Wrist Score of 75 (fair) improved to 100 (excellent).
    UNASSIGNED: The surgeon should always keep in mind the possibility of a tumor at the rare site and accurately diagnose the tumor with the help of imaging modalities and biopsy.
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  • 文章类型: Case Reports
    称为软骨瘤的良性软骨病变通常出现在四肢的长骨中。这个病例报告,然而,提请注意锁骨内侧端附近的内生软骨瘤的罕见和不寻常的外观。因为不寻常的位置,诊断过程非常复杂,这给医生带来了挑战。我们提供临床,放射学和组织学结果,最终允许一个准确的诊断。这个例子强调了需要考虑良性病变的非典型位置,并强调了在意外的临床环境中彻底诊断方法的必要性。由于锁骨软骨瘤的发生是一种罕见的实体,有时会误导临床医生,医疗保健提供者必须足够警惕,以保证及时准确的诊断,以便及时干预。
    Benign cartilaginous lesions called enchondromas usually appear in the long bones of the limbs. This case report, however, draws attention to an uncommon and unusual appearance of enchondroma near the medial end of clavicle. Because of the unusual location, the diagnostic process was very complex, which presented a challengefor the physicians. We provide the clinical, radiological and histological results that finally allowed for an accurate diagnosis. This example highlights the need of taking into account atypical location for benign lesions and highlights the necessity of a thorough diagnostic approach in unexpected clinical settings. Since the occurrence of clavicular enchondromas is a rare entity and can at times mislead the clinician, healthcare providers must be vigilant enough to guarantee a prompt and accurate diagnosis for timely intervention.
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  • 文章类型: Journal Article
    教学要点:肋软骨样肿瘤可以模仿腹部肿块,当位于右侧软骨病时,可能提示肝脏起源。计算机断层扫描对于确定其起源和性质以及指导适当的治疗至关重要。
    Teaching Point: Costal chondroid tumors can mimic abdominal masses and, when located in the right hypochondrium, may suggest hepatic origin. Computed tomography is essential to determine their origin and nature and to guide appropriate treatment.
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  • 文章类型: Journal Article
    软骨肿瘤是一类以软骨基质存在为特征的大型异质性肿瘤。小叶生长和弓形,环状或爆米花状钙化模式。MRI显示T2加权序列中的高强度和对比后图像中的分叶状或间隔状起伏。在WHO2020分类中,软骨肿瘤被归类为良性,中间或恶性。尽管技术进步,它们继续对放射科医生和病理学家构成挑战,区分良性和恶性肿瘤是主要的困难,这就是为什么他们需要多学科的方法。本文介绍了2020年更新中引入的主要变化,描述了主要软骨肿瘤的影像学特征,并提供了区分良性和恶性肿瘤的放射学关键。
    Cartilaginous tumours are a large and heterogeneous group of neoplasms characterised by the presence of a chondroid matrix, with lobular growth and arcuate, ring-like or popcorn-like calcification patterns. MRI shows hyperintensity in T2-weighted sequences and a lobulated or septal relief in postcontrast images. In the WHO 2020 classification, chondral tumours are classified as benign, intermediate or malignant. Despite technological advances, they continue to pose a challenge for both the radiologist and the pathologist, being the main difficulty the differentiation between benign and malignant tumours, which is why they require a multidisciplinary approach. This paper describes the main changes introduced in the 2020 update, describes the imaging characteristics of the main cartilaginous tumours and provides the radiological keys to differentiate between benign and malignant tumours.
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  • 文章类型: Letter
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  • 文章类型: Case Reports
    病理性指骨骨折是指孤立性内软骨瘤的常见初始表现。中指骨的软骨瘤最常与术后运动范围缺陷相关。本报告描述了一个案例,其中在手术固定中指中内软骨瘤伴伸肌腱损伤的病理性骨折后,使用克氏针(K线)和同种异体骨修复手指运动。
    一名37岁的右手优势女子表现为左食指中指骨病理性骨折。患者选择进行手术干预,以稳定骨折并使近端指间关节(PIP)早期运动。手术固定术涉及肿瘤刮除术,用纵向K线进行断裂稳定和长度保持,具有硬化特性的同种异体骨填充骨缺损,和用于固定伸肌腱的背侧K线。术后11个月随访,同种异体移植几乎完全解决了,患者恢复了PIP90°屈曲和完全伸展。
    中指骨内生软骨瘤的病理性骨折容易因伸肌腱损伤和相关的术后运动丧失而发生并发症。植骨和克氏针固定可以早期动员手指运动,因此可能是治疗其他病理性骨折的有用技术。
    UNASSIGNED: Pathologic phalangeal fracture is a common initial presentation of solitary enchondroma of the finger. Enchondromas of the middle phalanx are most frequently associated with post-operative range of motion deficits. This report describes a case in which the use of Kirschner wires (K-wires) and allograft bone were used to salvage finger motion following surgical fixation of pathologic fracture of a middle phalanx enchondroma with extensor tendon injury.
    UNASSIGNED: A 37-year-old right hand dominant woman presents with pathologic fracture of the left index finger middle phalanx. The patient elected for surgical intervention to stabilize fracture and enable early motion at the proximal interphalangeal joint (PIP). Surgical fixation involved tumor curettage, fracture stabilization and length preservation with longitudinal K-wires, allograft bone with hardening properties to fill the bony defect, and dorsal K-wires for securing the extensor tendon. At follow-up 11 months postoperatively, the allograft had almost completely resolved, and the patient had regained PIP flexion of 90° and full extension.
    UNASSIGNED: Pathologic fracture of middle phalanx enchondroma is prone to complication by extensor tendon injury and associated post-operative loss of motion. Bone grafting and Kirschner wire fixation allowed for early mobilization of finger motion and thus may be a useful technique for use in treatment of other pathologic fractures.
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  • 文章类型: Journal Article
    软骨瘤是常见的良性骨肿瘤,通常出现在手中。它们可以引起肿胀和疼痛等症状,但往往不被注意到。如果肿瘤扩张,它可以减少骨皮质并使骨骼容易骨折。诊断基于临床调查和影像学检查。尽管它们在射线照片上有典型的外观,在急性创伤环境中,它们可能主要被误诊或完全无法识别。深度学习模型在图像分类和模式识别中的早期应用表明,该技术也可以用于检测手X射线照片中的内生软骨瘤。我们用414张内植骨X射线照片训练了一个深度学习模型,以从手部X射线照片中检测内植骨。使用一组单独的131张X射线照片(47%带有内生软骨瘤)来评估经过训练的深度学习模型的性能。三位临床专家的Enchondroma注释是我们评估深度学习模型性能的基本事实。我们的深度学习模型从62个内生X射线照片中检测到56个内生X射线。受试者操作曲线下面积为0.95。区域统计重叠的F1评分为69.5%。我们的深度学习模型可能是X光片筛查和引起怀疑的有用工具。
    Enchondromas are common benign bone tumors, usually presenting in the hand. They can cause symptoms such as swelling and pain but often go un-noticed. If the tumor expands, it can diminish the bone cortices and predispose the bone to fracture. Diagnosis is based on clinical investigation and radiographic imaging. Despite their typical appearance on radiographs, they can primarily be misdiagnosed or go totally unrecognized in the acute trauma setting. Earlier applications of deep learning models to image classification and pattern recognition suggest that this technique may also be utilized in detecting enchondroma in hand radiographs. We trained a deep learning model with 414 enchondroma radiographs to detect enchondroma from hand radiographs. A separate test set of 131 radiographs (47% with an enchondroma) was used to assess the performance of the trained deep learning model. Enchondroma annotation by three clinical experts served as our ground truth in assessing the deep learning model\'s performance. Our deep learning model detected 56 enchondromas from the 62 enchondroma radiographs. The area under receiver operator curve was 0.95. The F1 score for area statistical overlapping was 69.5%. Our deep learning model may be a useful tool for radiograph screening and raising suspicion of enchondroma.
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  • 文章类型: Case Reports
    •多例病例报告发表于同时出现颗粒细胞瘤的Ollier病患者。•正在用雄激素和雌激素治疗更多的医疗状况,包括性别烦躁不安.•应谨慎使用活性激素治疗的变性患者。•提供者应考虑对激素反应性医疗条件进行预筛查。
    •Multiple case reports are published on patients with Ollier\'s disease presenting simultaneously with granulosa cell tumors.•More medical conditions are being treated with androgens and estrogens, including gender dysphoria.•Caution should be given to transgender patients on active hormonal therapy.•Providers should consider prescreening for hormonally responsive medical conditions.
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  • 文章类型: Case Reports
    Maffucci综合征是一种罕见的先天性非遗传性综合征,在美国已报道少于300例。它的特点是多个内生软骨,血管瘤,很少见淋巴管瘤.软骨瘤可能发生恶性转化为软骨肉瘤。监测在检测早期恶性转化中起着至关重要的作用。氟脱氧葡萄糖(FDG)PET/CT,虽然失宠,可以被医生用作成像模态来确定这种转换,及时管理和干预。在这份报告中,我们分享我们对这种情况的经验。
    Maffucci\'s syndrome is a rare congenital nonhereditary syndrome with less than 300 cases having been reported in the United States. It is characterized by multiple enchondromas, hemangiomas, and rarely lymphangiomas. Enchondromas may undergo malignant transformation to chondrosarcomas. Surveillance plays a vital role in detecting early malignant transformation. Fluorodeoxyglucose (FDG) PET/CT, although falling out of favor, may be utilized as an imaging modality by physicians to determine such transformation, allowing for timely management and intervention. In this report, we share our experience with such a case.
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