ejaculation preservation

射精保存
  • 文章类型: Journal Article
    目的:射精功能障碍是前列腺增生手术中最常见的副作用。改进的技术已经出现,目的是在不损害阻塞缓解的情况下保持顺行射精。没有标准化或验证。PARTURP研究是一项研究部分与完全前列腺切除术的随机研究。我们进行了一次研究者共识会议,以定义理想的手术技术,以实现保留射精的同时正确缓解梗阻。
    方法:召开了PARTURP研究的所有研究者的专家共识会议,以使用名义分组方法定义通用技术。目标是定义要切除的区域和要保留的区域;定义适当解除障碍的标准;定义适当保存射精的标准。
    结果:所有研究人员(n=15)参加了共识会议,并获得了所有参与者之间的协议。要保留的解剖标志位于Verumontanum周围和前列腺尿道的后部。这些结构必须保存到距离Verumontanum2厘米处。参与者同意需要保留所有要保留的区域的尿道粘膜,并在切除区域到达摘除平面。
    结论:PARTURP随机研究的研究者已经确定了射精手术的解剖标志。这些地标将在研究期间使用,这种保留射精技术的临床结果将与完全切除和长达3年的随访进行比较。
    OBJECTIVE: Ejaculatory dysfunction is the most common side effect of benign prostatic hyperplasia surgery. Modified techniques have emerged with the aim of preserving antegrade ejaculation without compromising obstruction relief. None are standardized or validated. The PARTURP study is a randomized study investigating partial versus complete prostate resection. We conducted an investigator consensus meeting to define the ideal surgical technique to achieve both correct obstruction relief with ejaculation preservation.
    METHODS: An expert consensus meeting involving all investigators of the PARTURP study took place to define a common technique using the nominal group methodology. The objectives were to define the areas to be resected and the areas to be preserved; to define the criteria for proper obstruction relief; to define the criteria for proper ejaculation preservation.
    RESULTS: All investigators (n = 15) attended the consensus meeting, and agreement between all the participants was obtained. The anatomical landmarks to be preserved are located around the verumontanum and along the posterior part of the prostatic urethra. These structures must be preserved up to 2 cm from the verumontanum. The participants agreed on the need to preserve the urethral mucosa in all the areas to be preserved and to reach the enucleation plane in the areas of resection.
    CONCLUSIONS: Anatomical landmarks for ejaculation-sparing surgery have been defined by the investigators of the PARTURP randomized study. These landmarks will be used during the study, and the clinical outcomes of this ejaculation-sparing technique will be compared with complete resection with up to 3 years follow-up.
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  • 文章类型: Journal Article
    尽管传统的经尿道前列腺电切术(TURP)在改善泌尿症状和流速方面非常成功,据报道,顺行射精丢失的发生率较高。因此,我们的目的是前瞻性比较新型膀胱颈和阴部上双保留TURP与常规TURP的疗效和结局,以改善排尿和射精.
    在2019年1月至2020年11月之间,所有符合资格标准的良性前列腺增生(BPH)患者在随机分组后接受了常规TURP(第1组)或联合膀胱颈和输卵管上保留TURP(第2组)。比较两组的功能结局,包括国际前列腺症状评分(IPSS),峰值流速,排尿后残留尿液,围手术期变量和术后并发症。使用国际勃起功能指数-问题9(IIEF-9)和射精投影评分(EPS)评估射精。
    共有90名患者被随机分组,45个分别为第1组和第2组。两组的人口统计学特征具有可比性。第1组逆行射精和膀胱颈挛缩明显增高。两组在3个月时IPSS(26.12±2.88至4.69±0.87(第1组)vs第2组的26.60±3.45至4.36±1.74)和Qmax(第1组的7.03±2.71至24.36±3.82mL/svs第2组的6.29±2.64至25.28±4.33mL/s)均有显着改善。然而,在6个月时,IPSS和Qmax有显著差异.第2组的IIEF-9评分与术前相似(4.18±0.75)和2.58±0.86(第1组)。第1组的EPS显着下降,但与第2组的术前EPS相似。与第1组的22.22%相比,第2组的顺行射精保留率为88.89%。
    双膀胱颈和阴部射精保留TURP在防止前列腺<50cc的逆行射精和膀胱颈挛缩方面优于常规TURP,具有相当的功能效果。围手术期和术后发病率。
    UNASSIGNED: Although conventional transurethral resection of the prostate (TURP) is highly successful in improving urinary symptoms and flow rates, a higher incidence of loss of antegrade ejaculation has been reported. Therefore, we aimed at prospectively comparing the efficacy and outcomes of a novel dual bladder neck and supramontanal sparing TURP to conventional TURP to improve voiding and ejaculation.
    UNASSIGNED: Between January 2019 and November 2020, all patients with benign prostatic hyperplasia (BPH) satisfying the eligibility criteria underwent either conventional TURP (Group 1) or combined bladder neck and supramontanal sparing TURP (Group 2) after randomisation. The groups were compared for functional outcomes including International Prostate Symptom Score (IPSS), peak flow rates, post-void residual urine, perioperative variables and postoperative complications. Ejaculation was assessed with International Index of Erectile Function-Question 9 (IIEF-9) and Ejaculation Projection score (EPS).
    UNASSIGNED: A total of 90 patients were randomised, 45 each to Group 1 and 2 respectively. The demographic profiles across both groups were comparable. Retrograde ejaculation and bladder neck contracture were significantly higher in Group 1. Both groups demonstrated significant improvement in the IPSS (26.12 ±2.88 to 4.69 ±0.87 (Group 1) vs 26.60 ±3.45 to 4.36 ±1.74 in Group 2) and Qmax (7.03 ±2.71 to 24.36 ±3.82 mL/s in Group 1 vs 6.29 ±2.64 to 25.28 ±4.33 mL/s in Group 2) at 3 months. However, a significant difference in IPSS and Qmax were recorded at 6 months. IIEF-9 score in Group 2 remained similar to preoperative profile (4.18 ±0.75) vs 2.58 ±0.86 (Group 1). EPS significantly decreased in Group 1 but remained similar to preoperative EPS in Group 2. Antegrade ejaculation was preserved in 88.89% in Group 2 as compared to 22.22% in Group 1.
    UNASSIGNED: Dual bladder neck and supramontanal ejaculation preserving TURP is superior to conventional TURP in preventing retrograde ejaculation and bladder neck contractures in prostates <50 cc with comparable functional results, perioperative and postoperative morbidity.
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  • 文章类型: Journal Article
    OBJECTIVE: To review the current data on retrograde ejaculation (RE) and ejaculatory dysfunction (EjD) after endoscopic and minimally invasive surgical treatment of benign prostatic obstruction (BPO) and, their perceived impact in the quality of life (QoL) and sexual life of patients and their partners.
    METHODS: Narrative review of systematic reviews (SR) assessing comparative rates of RE, EjD or erectile dysfunction (EF) was carried out. Relevant articles on the prevalence of RE, EjD or EF and on their impact in the QoL or sexual life of patients and partners were manually selected based on relevance.
    RESULTS: Twelve SRs reporting on comparisons of different endoscopic/minimally invasive treatments of BPO were found. Data on outcomes varied widely. Overall, after conventional TURP or laser techniques 42-75% of patients present RE. Prostatic incision and ablative procedures present lowest rates of de novo RE or EjD whereas laser adenomectomy and ejaculation preservation procedures preserve antegrade ejaculation in 46-68% of patients. EjDs is associated to LUTS and present in 10% of sexualy active men before intervention. It modulates the QoL and sexual life of the couple. In spite of the scarce literature assessing patient\'s and partner\'s perception of postoperative EjD, it strongly suggests that both parties value the maintenance of the ejaculatory function.
    CONCLUSIONS: Ejaculation-preserving techniques and minimally invasive techniques successfully prevent BPO treatment-induced RE or EjD in 70-100% of the cases. While this is appealing to patients and spouses, technique selection and treatment durability are issues to be discussed with the couple.
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  • 文章类型: Journal Article
    OBJECTIVE: Ejaculatory dysfunction is the most common side effect related to surgical treatment of benign prostatic obstruction (BPO). Nowadays, modified surgical techniques and non-ablative techniques have emerged with the aim of preserving antegrade ejaculation. Our objective was to conduce a systematic review of the literature regarding efficacy on ejaculatory preservation of modified endoscopic surgical techniques, and mini-invasive non-ablatives techniques for BPO management.
    METHODS: A systematic review of the literature was carried out on the PubMed database using the following MESH terms: \"Prostatic Hyperplasia/surgery\" and \"Ejaculation\", in combination with the following keywords: \"ejaculation preservation\", \"photoselective vaporization of the prostate\", \"photoselective vapo-enucleation of the prostate\", \"holmium laser enucleation of the prostate\", \"thulium laser\", \"prostatic artery embolization\", \"urolift\", \"rezum\", and \"aquablation\".
    RESULTS: The ejaculation preservation rate of modified-TURP ranged from 66 to 91%. The ejaculation preservation rate of modified-prostate photo-vaporization ranged from 87 to 96%. The only high level of evidence studies available compared prostatic urethral lift (PUL) and aquablation versus regular TURP in prospective randomized-controlled trials. The ejaculation preservation rate of either PUL or aquablation compared to regular TURP was 100 and 90 versus 34%, respectively.
    CONCLUSIONS: Non-ablative therapies and modified endoscopic surgical techniques seemed to be reasonable options for patients eager to preserve their ejaculatory functions.
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