donor site morbidity

供体部位发病率
  • 文章类型: Journal Article
    对颌面重建患者供体部位发病率的文献进行了系统综述。比较了两种广泛使用的皮瓣,即游离腓骨皮瓣(FFF)和DCIA皮瓣,以回答以下问题:(1)使用FFF和DCIA皮瓣进行颌面部重建的患者的供体部位发病率是否存在显着差异?(2)是否应将供体部位发病率视为选择皮瓣进行重建的标准。
    搜索策略基于PRISMA指南。检索了各种电子数据库。在回顾我们系统综述中的七篇文章时,我们发现口腔鳞状细胞癌是导致头颈部缺损的最常见病理,需要用游离皮瓣重建。
    共调查了531名使用FFF和DCIA皮瓣进行颌面部重建的参与者。这项研究包括两种性别。在微血管手术后评估参与者的短期和长期供体部位发病率。平均年龄为45-60岁。七项研究中有三项显示DCIA在供体部位的并发症比腓骨组少。而另外两项研究证明FFF优于DCIA。一项研究证明,两个皮瓣的供体部位发病率较低。
    游离腓骨是头颈部重建中的首选皮瓣,其供体部位发病率与DCIA相当。髂动脉皮瓣的优点包括自然弯曲,丰富的垂直和水平骨高度,用于骨轮廓和骨整合,隐藏的疤痕,在长期随访中,伤口愈合问题的发生率低,对功能和生活质量的影响最小。因此,这使得它的自由瓣的选择,一个无法避免。该系统评价在PROSPERO(CRD42021268949)注册。
    UNASSIGNED: A systematic review of the literature on the donor site morbidity in patients undergoing Maxillofacial reconstruction was performed. The two widely used flaps namely free fibula flap (FFF) and DCIA flap were compared to answer the following questions: (1) Is donor site morbidity significantly different in patients undergoing maxillofacial reconstruction with FFF and DCIA flap? (2) Should donor site morbidity be considered as the criteria for choosing the flap for reconstruction.
    UNASSIGNED: The search strategy was based on PRISMA guidelines. Various electronic databases were searched. On reviewing the seven articles included in our systematic review, we found out oral squamous cell carcinoma to be the most common pathology leading to the defects in head and neck region requiring reconstruction with free flaps.
    UNASSIGNED: A total of 531 participants were investigated who underwent maxillofacial reconstruction using FFF and DCIA flap. The study included both the genders. The participants were assessed for short- and long-term donor site morbidity after the microvascular surgery. Mean age is 45-60 years. Three out of seven studies showed DCIA to have lesser complications at donor site than fibula group. While other two studies proved FFF to be better than DCIA. One study proved low donor site morbidity with regard to both the flap.
    UNASSIGNED: The free fibula being the flap of choice in head and neck reconstruction has a comparable donor site morbidity to DCIA. The advantages of the iliac artery flap include natural curvature, abundant vertical and horizontal bone height for bone contouring and osseointegration, hidden scar, low incidence of wound healing problems and minimal effect on function and quality of life at long-term follow-up. Thus, it makes it the free flap of choice that one cannot avoid. This systematic review was registered at PROSPERO (CRD42021268949).
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  • 文章类型: Journal Article
    在前交叉韧带重建(ACLR)后6个月的短期随访中,通过超声成像研究股四头肌腱供体部位的愈合情况,并研究临床结果。
    在2019年3月至2020年8月之间,本研究回顾性纳入了61个膝盖。术中,长度,测量收获的QT移植物的宽度和厚度。在6个月的随访中,患者由五名放射科医生中的一名进行评估,遵循相同的协议来计算缺陷体积,患者在视觉模拟量表上对疼痛进行了自我评估,国际膝关节文献委员会(IKDC)和膝关节损伤和骨关节炎结果评分(KOOS)。
    术中,QT移植物的体积为4635.4±912.5mm3。术后,在6.5±0.7个月时进行超声检查,缺损体积为323.3±389.2mm3,代表供体部位的93%±9%的愈合率。在至少6个月的随访中,IKDC为61.6±16,KOOS为70.2±16.6。年龄与治愈率显着相关(β:-0.005;p=0.032)。
    随访6个月时,根据超声测量,QT供体部位的缺损大小已愈合93±9%,留下的平均缺损体积为323.3mm3.这表明QT在移植物收获后具有很高的愈合能力,10例患者在手术后6个月达到完全缺损闭合。这些发现的临床相关性是股四头肌腱供体部位的愈合率高,但是外科医生应该意识到老年患者的治愈率较低。
    四级,回顾性病例系列。
    UNASSIGNED: To investigate the healing of the quadriceps tendon donor site after partial thickness graft harvesting through ultrasound imaging at a short-term follow-up of 6-month following anterior cruciate ligament reconstruction (ACLR) and to investigate the clinical outcomes.
    UNASSIGNED: Between March 2019 and August 2020, 61 knees were retrospectively included in this study. Intraoperatively, the length, width and thickness of the harvested QT graft were measured. At a 6-month follow-up, patients were assessed by one of five radiologists, following the same protocol to calculate the defect volume, and patients performed a self-evaluation of pain on the Visual Analogue Scale, International Knee Documentation Committee (IKDC) and the Knee injury and Osteoarthritis Outcome Scores (KOOS).
    UNASSIGNED: Intraoperatively, the QT grafts had a volume of 4635.4 ± 912.5 mm3. Postoperatively, ultrasound was performed at 6.5 ± 0.7 months, and the defect volume was 323.3 ± 389.2 mm3, representing a healing rate of 93% ± 9% of the donor site. At a minimum 6-month follow-up, IKDC was 61.6 ± 16 and KOOS was 70.2 ± 16.6. Age was significantly associated with the healing rate (β: -0.005; p = 0.032).
    UNASSIGNED: At 6 months follow-up, the defect size of the QT donor site had healed by 93 ± 9% leaving a mean defect volume of 323.3 mm3 according to ultrasound measurements. This suggests that the QT has a high capacity for healing after graft harvesting, with 10 patients reaching full defect closure 6 months after surgery. The clinical relevance of these findings is that the quadriceps tendon donor site has high rates of healing, but surgeons should be aware of lower healing rates in older patients.
    UNASSIGNED: Level IV, retrospective case series.
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  • 文章类型: Journal Article
    背景:这项研究比较了患者报告的功能和美学结果,即对radial骨前臂游离皮瓣(RFFF)供体部位的分裂厚度皮肤移植(STSG)和斧头皮瓣闭合。
    方法:对RFFF(2015-2020)患者进行回顾性分析。那些愿意参加患者报告结果(PRO)的人填写了患者-观察者疤痕评估量表(POSAS)和密歇根手结果问卷(MHOQ)。
    结果:198例患者符合我们的纳入标准,81例患者参加了PRO。STSG与斧头瓣的肌腱暴露率较高(11vs.1,p=0.0019),但皮肤坏死率较低(5vs.16,p=0.0190)和表皮溶解(1vs.12,p=0.0028)。在POSAS的所有领域中,STSG的疤痕质量均优于斧头瓣。两组MHOQ评分相似,总分无统计学差异(p=0.2165)。
    结论:STSG在日常生活活动中似乎不太妥协,更好的满意度和改进的疤痕质量比斧头皮瓣,但肌腱暴露率较高。
    方法:3喉镜,2024.
    BACKGROUND: This study compares patient-reported functional and aesthetic outcomes of split-thickness skin graft (STSG) versus hatchet flap closure of radial forearm free flap (RFFF) donor site.
    METHODS: Patients with RFFF (2015-2020) were retrospectively identified. Those willing to participate in patient-reported outcomes (PRO) filled out Patient-Observer Scar Assessment Scale (POSAS) and Michigan Hand Outcome Questionnaire (MHOQ).
    RESULTS: 198 patients met our inclusion criteria and 81 participated in PRO. There was a higher rate of tendon exposure in STSG versus hatchet flap (11 vs. 1, p = 0.0019), but a lower rate of skin necrosis (5 vs. 16, p = 0.0190) and epidermolysis (1 vs. 12, p = 0.0028). Scar quality in STSG was superior to hatchet flap in all domains of POSAS. MHOQ scores were similar between both groups with no statistical difference in overall scores (p = 0.2165).
    CONCLUSIONS: STSG appeared to have less compromise in activities of daily living, better satisfaction and improved scar quality than hatchet flap, but a higher rate of tendon exposure.
    METHODS: 3 Laryngoscope, 2024.
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  • 文章类型: Journal Article
    当需要用于中等大小缺损的细薄组织时,建议使用颞顶瓣(TPF)。这种皮瓣最常用的形式是耳廓重建。本文讨论了这种皮瓣在耳廓以外的面部重建中的应用,强调供体部位的发病率。
    在这项回顾性研究中,口腔颌面外科的存档文件,医学科学大学,马什哈德,伊朗从2016年至2020年进行了评估。包括TPF用于面部重建的患者。检查皮瓣存活,并以皮肤疤痕和额神经分支损伤的形式评估供体部位的发病率。
    该皮瓣用于8例患者的面部重建。所有病例都经历过脱发,当还包括头皮皮肤时,这是最大的。所有患者都可以抬起眉毛,这意味着面神经的完整额支。
    TPF是一种用于面部重建的多功能皮瓣。然而,这种皮瓣的复合筋膜皮肤形式的脱发率高。
    UNASSIGNED: Temporoparietal flap (TPF) is recommended when thin delicate tissue for medium sized defect is needed. The most used form of this flap is for auricle reconstruction. In this article usage of this flap for facial reconstruction other than auricle is discussed, emphasing on donor site morbidity.
    UNASSIGNED: In this retrospective study, archived files of the Department of Oral and Maxillofacial Surgery, University of Medical Sciences, Mashhad, Iran were evaluated from 2016-2020. Patients whom TPF was used for facial reconstruction were included. Flap survival was checked and donor site morbidity was evaluated in the form of skin scar and frontal nerve branch injury.
    UNASSIGNED: This flap was used in 8 patients for facial reconstruction. All the cases had experienced Alopecia and this was the greatest when the skin of scalp was also included. All of the patients could elevate the eyebrow that means intact frontal branch of facial nerve.
    UNASSIGNED: TPF is a versatile flap for facial reconstruction. However, alopecia is high in composite fasciocutaneous form of this flap.
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    文章类型: Journal Article
    In contrast to tangential excision, enzymatic debridement with NexoBrid® selectively removes non-viable tissue, allowing some deep dermal burn wounds to still heal conservatively. In this retrospective study, we investigated the reduction in surgery and associated scarring following enzymatic debridement in definitely deep burns as proven by laser Doppler imaging. One hundred two exclusively laser Doppler imaging-blue regions of interest where there was no doubt at all about the surgical indication, were selected for analysis in 32 patients treated with NexoBrid®. The total surface area of the 102 exclusively blue regions of interest was 5,086.4cm2. NexoBrid® resulted in a substantial reduction in the need for autografts as 1,986.9cm2 (39%) healed with conservative treatment. This corresponded with a significant reduction in patients (56.3%) requiring surgery. Exclusively laser Doppler imaging-blue regions of interest treated surgically with split thickness skin grafts required significantly more time to heal compared to conservative treatment (37.8±17.5 vs. 27.0±10.5 days). A very limited rate of hypertrophic scarring (16.7%) was observed. This is the first paper demonstrating a proven and significant reduction in the extent of autografting as well as in the number of surgical procedures after selective enzymatic debridement in objectively laser Doppler imaging-defined and therefore proven deep burns. Even after extended conservative treatment with prolonged healing times following NexoBrid®, hypertrophic scar formation was limited (5/54 regions of interest, 9.3%). Also in operated patients, the incidence of hypertrophic scarring following a strict regimen of aftercare was low (12/48 regions of interest, 25%).
    À la différence de l’excision chirurgicale tangentielle, le débridement enzymatique au Nexobrid® ne s’intéresse qu’au tissu nécrosé ce qui permet la cicatrisation spontanée de certaines brûlures intermédiaires. Dans cette étude rétrospective, nous avons évalué la diminution des interventions chirurgicales (et des séquelles y afférant) en cas d’utilisation de l’excision enzymatique sur des brûlures affirmées comme profondes par Imagerie Laser- Doppler (ILD). Nous avons analysé 102 régions d’intérêt, apparaissant bleues à l’ILD chez 32 patients traités par Nexobrid®, représentant une surface totale de 5 086,4 cm2. Ceci a permis une cicatrisation spontanée de 1 986,9 cm2 (39% de l’ensemble et 56,3% chez les patients ayant dû être opérés). Les patients traités par excision- greffe sont restés significativement plus longtemps que ceux ayant cicatrisé spontanément (37,8 +/- 17,5 j VS 27 +/- 10,5). L’incidence globale des cicatrices hypertrophiques était basse (16,7%). Ceci est la première publication montrant une diminution significative de la surface greffée et du nombre d’interventions chirurgicales après l’utilisation d’une excision enzymatique chez des patients souffrant de brûlures définies comme profondes par ILD. Même après une cicatrisation spontanée longue après Nexobrid®, l’incidence des cicatrices hypertrophiques reste faible (5/54 régions d’intérêt - 9,3%) quand elle s’élève à 25% après excision- greffe (12/48).
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  • 文章类型: Journal Article
    目的:前臂游离皮瓣(RFFF)广泛应用于头颈部重建,然而,其供体部位缺陷仍然是一个显著的缺点。内侧腓肠动脉穿支自由襟翼(MSAPFF)被认为是RFFF的替代襟翼。本研究旨在全面分析其特点,结果,以及它们对患者生活质量的影响。
    方法:本研究纳入了2017年2月至2023年4月期间使用RFFF和MSAPFF进行口腔重建的所有患者。襟翼特性,记录并比较结果和术后并发症。主观供体部位发病率,美学和功能结果,和生活质量也进行了分析。
    结果:该研究包括76例患者:37例接受了RFFF重建,和39MSAPFF。RFFF和MSAPFF之间的成功率没有显着差异(97.2%vs97.4%),皮瓣尺寸(4.8×8.8cm2对5×9.8cm2),住院时间(15.5天比13.5天)和受体部位并发症(P>0.05)。然而,MSAPFF显示皮瓣厚度较大(P=0.001),较小的动脉口径(P=0.008),椎弓根长度较短(P=0.001),和更长的收获时间(P<0.001)。腕关节和踝关节运动的前后范围或受体部位并发症之间没有显着差异。MSAPFF显示供体部位发病率差异显著(P<0.05)。
    结论:MSAPFF是修复口腔缺陷的RFFF的绝佳替代品,除了小腿后部隐藏的疤痕之外,较大的皮瓣厚度,接受椎弓根长度和动脉口径。然而,与RFFF相比,应考虑收获时间和手术技能。
    结论:该研究强调了MSAPFF作为RFFF的替代选择的重要性,具有较低的供体部位发病率和较高的口腔重建成功率,并改善了患者消融手术后的生活质量。
    OBJECTIVE: Radial Forearm Free flap (RFFF) is widely used in head and neck reconstruction, yet its donor site defect remains a significant drawback. The Medial Sural Artery Perforator Free Flap (MSAPFF) is considered an alternative flap to RFFF. This study aims to comprehensively analyze their characteristics, outcomes, and their impact on patient quality of life.
    METHODS: All patients who underwent oral cavity reconstruction using RFFF and MSAPFF between February 2017 and April 2023 were included in this study. Flap characteristics, outcomes and post-operative complications were recorded and compared. Subjective donor site morbidity, aesthetic and functional results, and quality of life were also analyzed.
    RESULTS: The study included 76 patients: 37 underwent reconstruction with RFFF, and 39 with MSAPFF. There was no significance difference between the RFFF and MSAPFF regarding the success rate (97.2% vs 97.4%), flap size (4.8 × 8.8 cm2 vs 5 × 9.8 cm2), hospital of stay (15.5 days vs 13.5 days) and recipient site complications (P > 0.05). However, MSAPFF showed larger flap thickness (P = 0.001), smaller arterial caliber (P = 0.008), shorter pedicle length (P = 0.001), and longer harvesting time (P < 0.001). No significant difference was observed between the pre-and postoperative ranges of wrist and ankle movements or in recipient site complications. MSAPFF showed a significant difference in donor site morbidity (P < 0.05).
    CONCLUSIONS: The MSAPFF is an excellent alternative to the RFFF for repairing oral cavity defects, with additional advantage of a well-hidden scar on the posterior calf, a larger flap thickness, accepted pedicle length and arterial caliber. However, one should consider the harvesting time and surgical skills required in comparison to the RFFF.
    CONCLUSIONS: The study highlights the importance of the MSAPFF as an alternative option for RFFF with less donor site morbidity and high success rate in oral cavity reconstruction and improved patient Quality of life after ablative surgery.
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  • 文章类型: Journal Article
    这篇全面的综述探讨了重建手术领域中皮肤转移技术中供体部位发病率和瘢痕结局的复杂性。这篇综述综合了现有文献,通过调查广泛的嫁接方法,阐明了影响结果的多方面因素。从传统的自体移植到尖端的组织工程方法。关键发现强调了移植物特征的复杂相互作用,外科技术,和患者特定的变量。临床实践倡导者对细微差别的影响,以患者为中心的方法,结合新兴的微创手术和辅助治疗。这篇综述最后提出了对未来研究的建议,强调纵向研究的重要性,比较分析,患者报告的结果,先进的成像技术,组织工程创新的探索。这种合成促进了我们对供体部位发病率和疤痕结果的理解。它提供了完善临床协议的路线图,最终在重建手术中提高治疗效果和患者健康之间的微妙平衡。
    This comprehensive review delves into the intricacies of donor site morbidity and scar outcomes in skin transfer techniques central to the field of reconstructive surgery. The review synthesizes existing literature to illuminate the multifaceted factors influencing outcomes by surveying a broad spectrum of grafting methods, from traditional autografts to cutting-edge tissue engineering approaches. Key findings underscore the complex interplay of graft characteristics, surgical techniques, and patient-specific variables. The implications for clinical practice advocate for a nuanced, patient-centered approach, incorporating emerging minimally invasive procedures and adjuvant therapies. The review concludes with recommendations for future research, emphasizing the importance of longitudinal studies, comparative analyses, patient-reported outcomes, advanced imaging techniques, and exploration of tissue engineering innovations. This synthesis advances our understanding of donor site morbidity and scar outcomes. It provides a roadmap for refining clinical protocols, ultimately enhancing the delicate balance between therapeutic efficacy and patient well-being in reconstructive surgery.
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  • 文章类型: Journal Article
    目的:儿童耳廓重建的单侧肋软骨获取(UCCH)往往会导致胸部畸形。因此,我们的研究旨在开发一种新的双侧肋软骨获取(BCCH)方法,以预防和减少胸部畸形。
    方法:接受UCCH(n=50)或BCCH(n=46)的单侧小耳畸形患者被纳入本研究。BCCH组的移植物是从同侧半胸部的第6肋软骨和其他半胸部的第7和第8软骨中收获的。进行计算机断层扫描和体格检查以确定手术后胸部轮廓中的任何身体畸形。手术后胸廓疤痕的外观使用疤痕压迫评估和评定量表(SCAR)和视觉模拟量表(VAS化妆品)进行评估。使用数字评定量表(NRS)来量化供体部位的疼痛。在随访期间评估重建的耳朵。
    结果:BCCH组没有患者出现胸廓畸形,UCCH组中有16例患者出现轻度(n=12)或重度(n=4)胸畸形(p<0.001)。SCAR(3.09vs.2.92,p=0.580)和VAS评分(0.96与0.90,p=0.813)两组之间没有显着差异。对于两个治疗臂,NRS评分在术后第一天最高,在10天内逐渐下降.两组的NRS评分和重建耳朵的美学效果无明显差异。
    结论:BCCH方法有效地降低了供体部位胸廓畸形的发生率,而不会增加患者的术后疼痛和美容问题。它可以在临床上用于改善肋软骨移植物的患者预后。
    方法:4喉镜,2024.
    OBJECTIVE: Unilateral costal cartilage harvesting (UCCH) for auricle reconstruction in children tends to cause thoracic deformities. Therefore, our study aimed to develop a novel bilateral costal cartilage harvesting (BCCH) method to prevent and reduce thoracic deformities.
    METHODS: Patients with unilateral microtia who underwent either UCCH (n = 50) or BCCH (n = 46) were enrolled in this study. The grafts for the BCCH group were harvested from the 6th costal cartilage of the ipsilateral hemithorax and the 7th and 8th cartilage from the other hemithorax. Computed tomography and physical examination were performed to identify any physical deformities in the chest contours post-surgery. The cosmetic appearance of the thoracic scars post-surgery was evaluated using the Scar Cosmesis Assessment and Rating Scale (SCAR) and Visual Analogue Scales (VAS cosmetic). The numerical rating scale (NRS) was used to quantify the pain in donor sites. The reconstructed ears were assessed during the follow-up period.
    RESULTS: None of the patients in the BCCH group developed thoracic deformities, while 16 patients within the UCCH group developed mild (n = 12) or severe (n = 4) thoracic deformities (p < 0.001). The SCAR (3.09 vs. 2.92, p = 0.580) and VAS scores (0.96 vs. 0.90, p = 0.813) did not differ significantly between the two groups. For both treatment arms, the NRS scores were highest on the first-day post-surgery and gradually dropped over the 10 days. No significant differences were found in the NRS scores and the aesthetic outcomes of the reconstructed ears between the two groups.
    CONCLUSIONS: The BCCH method effectively reduced the incidence of thoracic deformity at the donor site without increasing postoperative pain and cosmetic concerns for patients. It could be used clinically to improve patient outcomes of costal cartilage grafts.
    METHODS: 4 Laryngoscope, 2024.
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  • 文章类型: Journal Article
    背景:桡骨前臂游离皮瓣(RFFF)是各种重建的主力。尽管RFFF抬高后有多种手术技术可用于供体部位的闭合,最常见的技术是使用分层厚度皮肤移植(STSG)或全厚度皮肤移植(FTSG)进行闭合.闭合可导致前臂和手的伤口并发症和功能以及美学损害。计划的系统评价和荟萃分析的目的是比较与伤口相关的功能相关和美学相关的结果与全厚度皮肤移植物(FTSG)和分裂厚度皮肤移植物(STSG)在radial前臂游离皮瓣(RFFF)供体部位闭合。
    方法:将进行系统评价和荟萃分析。将遵循系统审查和荟萃分析(PRISMA)指南的首选报告项目。电子数据库和平台(PubMed,Embase,Scopus,WebofScience,Cochrane中央对照试验登记册(中央),中国国家知识基础设施(CNKI)和临床试验注册(ClinicalTrials.gov,德国临床试验注册,ISRCTN注册表,国际临床试验注册平台)将使用预定义的搜索词进行搜索,直到2024年1月15日。重新搜索将在审查发表前12个月内进行。符合条件的研究应报告在提高RFFF和缺损闭合后供体部位并发症的发生。包括的闭合技术是使用全厚度皮肤移植物和分裂厚度皮肤移植物的技术。排除的闭合技术是不使用皮肤移植物的初次伤口闭合。结果被认为是受伤的-,功能-,和美学相关。将纳入的研究是随机对照试验(RCTs)以及前瞻性和回顾性比较队列研究。病例对照研究,没有对照组的研究,动物研究和尸体研究将被排除在外。每个研究将由两名审阅者以盲法方式进行筛选。第三位审稿人解决差异。将使用ROBINS-I和RoB2工具评估原始研究中的偏倚风险。使用ReviewManager(RevMan)5.4.1完成数据合成。如果合适,将进行荟萃分析。研究之间的变异性将使用I2指数进行评估。如有必要,将使用R。结果的证据质量最终将使用建议分级评估来评估,开发和评估(等级)方法。
    结论:这项研究的发现可能有助于我们了解两种闭合技术的并发症发生率,并可能对未来RFFF供体部位管理指南的制定具有重要意义。如果可用数据有限,并且有几个问题仍未得到回答,将需要更多的比较研究。
    背景:该协议是根据PRISMA-P协议扩展而开发的,并于2023年9月17日在国际前瞻性系统审查登记册(PROSPERO)注册(注册号CRD42023351903)。
    BACKGROUND: The radial forearm free flap (RFFF) serves as a workhorse for a variety of reconstructions. Although there are a variety of surgical techniques for donor site closure after RFFF raising, the most common techniques are closure using a split-thickness skin graft (STSG) or a full-thickness skin graft (FTSG). The closure can result in wound complications and function and aesthetic compromise of the forearm and hand. The aim of the planned systematic review and meta-analysis is to compare the wound-related, function-related and aesthetics-related outcome associated with full-thickness skin grafts (FTSG) and split-thickness skin grafts (STSG) in radial forearm free flap (RFFF) donor site closure.
    METHODS: A systematic review and meta-analysis will be conducted. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines will be followed. Electronic databases and platforms (PubMed, Embase, Scopus, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), China National Knowledge Infrastructure (CNKI)) and clinical trial registries (ClinicalTrials.gov, the German Clinical Trials Register, the ISRCTN registry, the International Clinical Trials Registry Platform) will be searched using predefined search terms until 15 January 2024. A rerun of the search will be carried out within 12 months before publication of the review. Eligible studies should report on the occurrence of donor site complications after raising an RFFF and closure of the defect. Included closure techniques are techniques that use full-thickness skin grafts and split-thickness skin grafts. Excluded techniques for closure are primary wound closure without the use of skin graft. Outcomes are considered wound-, functional-, and aesthetics-related. Studies that will be included are randomized controlled trials (RCTs) and prospective and retrospective comparative cohort studies. Case-control studies, studies without a control group, animal studies and cadaveric studies will be excluded. Screening will be performed in a blinded fashion by two reviewers per study. A third reviewer resolves discrepancies. The risk of bias in the original studies will be assessed using the ROBINS-I and RoB 2 tools. Data synthesis will be done using Review Manager (RevMan) 5.4.1. If appropriate, a meta-analysis will be conducted. Between-study variability will be assessed using the I2 index. If necessary, R will be used. The quality of evidence for outcomes will eventually be assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.
    CONCLUSIONS: This study\'s findings may help us understand both closure techniques\' complication rates and may have important implications for developing future guidelines for RFFF donor site management. If available data is limited and several questions remain unanswered, additional comparative studies will be needed.
    BACKGROUND: The protocol was developed in line with the PRISMA-P extension for protocols and was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 17 September 2023 (registration number CRD42023351903).
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  • 文章类型: Journal Article
    本研究旨在将ACL供体站点发病率(ACL-DSM)问卷翻译成土耳其语,并评估前交叉韧带(ACL)重建后个体中土耳其语版本的ACL-DSM问卷(ACL-DSM-Tr)的可靠性和有效性。这个过程涉及向前和向后翻译,文化适应,和ACL-DSM-Tr问卷对九十九名患者(平均年龄30.73±8.55岁)的验证。参与者完成ACL-DSM-Tr,国际膝关节纪录片委员会(IKDC)主观形式,ACL返回运动(ACL-RSI),和被遗忘的联合量表(FJS)问卷。内部一致性,可靠性,并对ACL-DSM-Tr的有效性进行了分析。ACL-DSM-Tr具有较高的内部一致性(Cronbach的alpha.755)和出色的重测可靠性(Spearman相关性r=.811,p<.001;Cronbach的alpha.890)。ACL-DSM-Tr评分与IKDC评分呈强正相关(r=.690,p<.001),与FJS评分呈中等正相关(r=.535,p<.001)。尽管ACL-DSM-Tr和ACL-RSI亚组得分之间存在相当的相关性,与ACL-RSI总分无显著相关性(p=0.297).总之,ACL-DSM-Tr展示了内部一致性,可靠性,以及ACL重建患者的有效性。该问卷有可能在监测患者满意度和评估ACL重建后供体部位的舒适度方面产生重大益处。
    This study aimed to translate the ACL Donor Site Morbidity (ACL-DSM) questionnaire into Turkish and assess the reliability and validity of the Turkish version of the ACL-DSM questionnaire (ACL-DSM-Tr) among individuals following anterior cruciate ligament (ACL) reconstruction. The process involved forward and back-translation, cultural adaptation, and validation of the ACL-DSM-Tr questionnaire on ninety-nine patients (mean age 30.73 ± 8.55 years). Participants completed ACL-DSM-Tr, International Knee Documentary Committee (IKDC) subjective form, ACL Return to Sport (ACL-RSI), and Forgotten Joint Scale (FJS) questionnaires. The internal consistency, reliability, and validity of the ACL-DSM-Tr were analyzed. The ACL-DSM-Tr demonstrated a high internal consistency (Cronbach\'s alpha .755) and excellent test-retest reliability (Spearman correlation r = .811, p < .001; Cronbach\'s alpha .890). The ACL-DSM-Tr score exhibited a strong positive correlation with the IKDC score (r = .690, p < .001) and a moderate positive correlation with the FJS score (r = .535, p < .001). Despite a fair correlation between ACL-DSM-Tr and ACL- RSI subgroup scores, no significant correlation was observed with the ACL-RSI total score (p = .297). In conclusion, the ACL-DSM-Tr demonstrated internal consistency, reliability, and validity in patients with ACL reconstruction. This questionnaire has the potential to yield significant benefits in monitoring patient satisfaction and evaluating the level of comfort experienced at the donor site following ACL reconstruction.
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