disengagement

脱离接触
  • 文章类型: Journal Article
    最近的社会道德发展理论认为,人类进化出一种在不同类型的互动中评估他人社会行为的能力。先前的婴儿研究发现,亲社会的触角和视觉偏好都超过了反社会药物。然而,是否可以通过触达行为和视觉注意力部署来推断积极或消极效价对参与积极追逐互动的代理人行为的归因(即,视觉注意力的脱离)仍然是一个悬而未决的问题。在这里,我们介绍了7个月大的婴儿(N=92),这些事件显示出积极的追逐互动。通过使用优先到达和注意任务(即,重叠范式),我们评估了婴儿是否以及如何评估攻击性追逐互动.结果表明,年幼的婴儿更喜欢接触受害者而不是侵略者,但这两种药剂都不会影响视觉注意力。此外,只有当动态线索和情感面部特征与代理人的社会角色一致时,这种达到的偏好才会出现。总的来说,这些发现表明,婴儿对攻击性互动的评估是基于婴儿对某些运动学线索的敏感性,这些线索表征了代理的作用,尤其是,这些动作和代理人的面部情感表达之间的一致性。
    Recent theories of socio-moral development assume that humans evolved a capacity to evaluate others\' social actions in different kinds of interactions. Prior infant studies found both reaching and visual preferences for the prosocial over the antisocial agents. However, whether the attribution of either positive or negative valence to agents\' actions involved in an aggressive chasing interaction can be inferred by both reaching behaviors and visual attention deployment (i.e., disengagement of visual attention) is still an open question. Here we presented 7-month-old infants (N = 92) with events displaying an aggressive chasing interaction. By using preferential reaching and an attentional task (i.e., overlap paradigm), we assessed whether and how infants evaluate aggressive chasing interactions. The results demonstrated that young infants prefer to reach the victim over the aggressor, but neither agent affects visual attention. Moreover, such reaching preferences emerged only when dynamic cues and emotional face-like features were congruent with agents\' social roles. Overall, these findings suggested that infants\' evaluations of aggressive interactions are based on infants\' sensitivity to some kinematic cues that characterized agents\' actions and, especially, to the congruency between such motions and the face-like emotional expressions of the agents.
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  • 文章类型: Journal Article
    目标:控制的需要是人类的基本动机,当被剥夺时,会导致人类行为的广泛而实质性的变化。我们旨在评估在现实生活中对个人控制构成严重威胁的情况下,控制剥夺的后果:长期失业。
    方法:使用样本N=1055名失业者(n=748)与工作者(n=307),我们研究了从控制剥夺反应的两个模型得出的预测:控制-恢复和脱离/退出.
    结论:我们发现,长期失业与强烈干扰心理和社会功能的心理状态相关。虽然我们的研究结果几乎没有支持对缺乏控制做出反应的控制-恢复模型,我们的结果提供了证据,表明长期失业的个人比工作的个人更脱离。他们更冷漠,不太可能参与重新获得控制权的努力,也不太可能积极地构建自己的未来。
    OBJECTIVE: The need for control is a fundamental human motivation, that when deprived can lead to broad and substantial changes in human behavior. We aimed to assess the consequences of control deprivation in a real-life situation that poses a severe threat to personal control: a prolonged unemployment.
    METHODS: Using a sample N = 1055 of unemployed (n = 748) versus working (n = 307) individuals, we examined predictions derived from two models of reactions to control deprivation: control-regaining and disengagement/withdrawal.
    CONCLUSIONS: We found that length unemployment is correlated with a psychological state strongly interfering with psychological as well as social functioning. While control-regaining models of responding to lack of control have received virtually no support from our findings, our results provide evidence that long-term unemployed individuals are more disengaged than working individuals. They are more apathetic, less likely to engage in control-regaining efforts and in active forms of construing one\'s own future.
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  • 文章类型: Journal Article
    低风险的测试表现通常反映了考生的能力和努力。在整个评估过程中,可以通过快速猜测行为来识别表现出低努力的考生。一旦确定了快速猜测,就提出了过多的方法来调整分数,但这些都受到强烈假设或考生被免职的困扰。在这项研究中,我们说明了如何使用IRTree模型来调整考生的快速猜测行为能力。我们的方法是灵活的,因为它不假设快速猜测行为和兴趣特征之间的独立性(例如,能力)也不需要删除从事快速猜测的考生。此外,除了感兴趣的特征外,我们的方法独特地允许同时建模脱离潜在特征。结果表明,相对于忽略快速猜测或以不同方式适应的模型,该模型对于估计考生在脱离潜在特征中的个体差异以及提供更精确的考生能力测量非常有用。一项模拟研究表明,我们的模型对具有快速反应的个体的兴趣特征估计的偏差较小,无论样本大小和样本中的快速响应率如何。最后,我们讨论了模型的扩展和未来研究的方向。
    Low-stakes test performance commonly reflects examinee ability and effort. Examinees exhibiting low effort may be identified through rapid guessing behavior throughout an assessment. There has been a plethora of methods proposed to adjust scores once rapid guesses have been identified, but these have been plagued by strong assumptions or the removal of examinees. In this study, we illustrate how an IRTree model can be used to adjust examinee ability for rapid guessing behavior. Our approach is flexible as it does not assume independence between rapid guessing behavior and the trait of interest (e.g., ability) nor does it necessitate the removal of examinees who engage in rapid guessing. In addition, our method uniquely allows for the simultaneous modeling of a disengagement latent trait in addition to the trait of interest. The results indicate the model is quite useful for estimating individual differences among examinees in the disengagement latent trait and in providing more precise measurement of examinee ability relative to models ignoring rapid guesses or accommodating it in different ways. A simulation study reveals that our model results in less biased estimates of the trait of interest for individuals with rapid responses, regardless of sample size and rapid response rate in the sample. We conclude with a discussion of extensions of the model and directions for future research.
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  • 文章类型: Journal Article
    返回:服务脱离在CHR-P(临床精神病高风险)的受试者中很常见,可能会恶化日常功能和增加未经治疗的精神病的持续时间。这就是为什么确定服务脱离的基线预测因素可以帮助更好地调整每个CHR-P个人的后续行动。
    目的:由于对该主题的研究很少,这项检查的目标是:(1)计算CHR-P样本中2年随访期间的服务脱离率;(2)检查基线时脱离接触的最相关预测因素.
    方法:所有年轻的CHR-P参与者都参加了“帕尔马高危精神状态”(PARMS)方案。在入境时,完成了全球功能评估(GAF)量表和阳性和阴性综合征量表(PANSS)。使用Cox回归分析。
    结果:本次考试招募了80名CHR-P受试者。在后续行动中,观察到2年服务脱离接触患病率为15%。服务脱离的统计上有力的预测因素是进入时抗抑郁药的处方较低。其他相关的基线预测因素是移民身份,更高的GAF分数,较低水平的焦虑抑郁症状和较低的接受心理社会干预。
    结论:CHR-P个体中焦虑抑郁特征的基线存在可能有利于参与专门的EIP服务。然而,需要实施改善患者动机和参与护理的策略。
    BACK: Service disengagement is common in subjects at CHR-P (clinical high risk for psychosis), potentially worsening daily functioning and increasing the duration of untreated psychosis. That is why to identify baseline predictors of service disengagement could help better tailoring follow-up on every CHR-P individual.
    OBJECTIVE: Since there are few studies on this topic, the goals of this examination were: (1) to calculate service disengagement rates in a CHR-P sample along 2-years of follow-up; and (2) to examine the most relevant predictive factors of disengagement at baseline.
    METHODS: All young CHR-P participants were enrolled within the \'Parma At-Risk Mental States\' (PARMS) protocol. At entry, the Global Assessment of Functioning (GAF) scale and the positive and negative syndrome scale (PANSS) were completed. Cox regression analyses were used.
    RESULTS: Hundred and eighty CHR-P subjects were recruited in this examination. During the follow-up, a 2-year service disengagement prevalence rate of 15% was observed. A statistically robust predictive factor of service disengagement was a lower prescription of antidepressant drug at entry. Other relevant baseline predictive factors were migrant status, higher GAF score, lower levels of anxious-depressive symptoms and a lower acceptance of psychosocial interventions.
    CONCLUSIONS: Baseline presence of anxious-depressive features in CHR-P individuals could favour engagement to specialized EIP services. However, implementing strategies to improve patients\' motivation and involvement in care are needed.
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  • 文章类型: Journal Article
    艾滋病毒(PWH)和丙型肝炎(HCV)患者脱离护理会增加不良健康结果的风险,并对实现全球消除艾滋病毒和HCV的目标构成重大障碍。根据乔安娜·布里格斯研究所的框架,我们进行了范围审查,以综合和突出文献中关于PWH和HCV之间(不参与)治疗的现有差距.我们使用8个电子数据库搜索了从开始到2023年5月在高收入国家的PWH和HCV中(不)参与护理的原始研究。我们的搜索产生了4462条不重复的记录,涵盖27项研究。(DIS)参与护理的定义是多种多样的,在保留率的操作和时间测量方面具有相当大的异质性。研究确定了与药物和物质使用相关的(DIS)参与的预测因素(n=5篇文章),临床因素(n=5),社会福利(n=4),和人口统计学特征(n=2)。当参与护理被视为暴露时,它与HCV治疗开始相关(n=3),实现持续的病毒学应答(n=2),并维持HIV病毒抑制(n=1)。改善PWH和HCV护理参与度的干预措施仅限于五项使用现金奖励(n=1)和个人病例管理(n=4)的研究。(Dis)参与护理是一个动态过程,受转移优先级的影响,这些优先级可能会“倾斜平衡”,朝向或远离与医疗保健专业人员的定期互动。然而,不一致的定义使得跨研究比较和荟萃分析几乎是不可能的。进一步的研究需要建立一个标准化的定义,以确定处于脱离接触高风险的患者,并开发干预措施,利用嵌套的HIV/HCV护理级联来保留和恢复失去护理的患者。
    Disengagement from care among people with HIV (PWH) and hepatitis C (HCV) increases the risks of adverse health outcomes and poses significant barriers to achieving global HIV and HCV elimination goals. In accordance with the Joanna Briggs Institute framework, a scoping review was conducted to synthesize and highlight existing gaps in the literature on (dis)engagement in care among PWH and HCV. We searched for original studies on (dis)engagement in care among PWH and HCV in high-income countries using eight electronic databases from inception to May 2023. Our search yielded 4462 non-duplicated records, which were scoped to 27 studies. Definitions of (dis)engagement in care were diverse, with considerable heterogeneity in how retention was operationalized and temporally measured. Studies identified predictors of (dis)engagement to be related to drug and substance use (n = 5 articles), clinical factors (n = 5), social and welfare (n = 4), and demographic characteristics (n = 2). When engagement in care was treated as an exposure, it was associated with HCV treatment initiation (n = 3), achieving sustained virological response (n = 2), and maintaining HIV viral suppression (n = 1). Interventions to improve care engagement among PWH and HCV were limited to five studies using cash incentives (n = 1) and individual case management (n = 4). (Dis)engagement in care is a dynamic process influenced by shifting priorities that may \'tip the balance\' towards or away from regularly interacting with healthcare professionals. However, inconsistent definitions render cross-study comparisons and meta-analyses virtually impossible. Further research needs to establish a standardized definition to identify patients at high risk of disengagement and develop interventions that leverage the nested HIV/HCV care cascades to retain and recover patients lost from care.
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  • 文章类型: Journal Article
    计算机认知训练(CCT)是一种可扩展的,耐受性良好的干预措施有望减缓认知能力下降。CCT的有效性往往受到缺乏有效参与的影响。精神疲劳是影响CCT有效参与的主要因素,特别是在有痴呆症风险的老年人中。需要可扩展的,自动措施,可以不断监测和可靠地检测CCT期间的精神疲劳。这里,我们开发并验证了一种新颖的循环视频转换(RVT)方法,用于在CCT期间使用视频记录的面部手势监测轻度认知障碍的老年人的实时精神疲劳.与用于精神疲劳的二元和多类别分类的现有模型相比,RVT模型实现了最高的平衡精度(79.58%)和精度(0.82)。我们还通过与CCT任务的反应时间显着相关来验证我们的模型(Waldχ2=5.16,p=0.023)。通过利用动态时间信息,RVT模型展示了准确测量实时精神疲劳的潜力,为未来CCT研究奠定基础,旨在通过及时预防精神疲劳来增强有效参与。
    Computerized cognitive training (CCT) is a scalable, well-tolerated intervention that has promise for slowing cognitive decline. The effectiveness of CCT is often affected by a lack of effective engagement. Mental fatigue is a the primary factor for compromising effective engagement in CCT, particularly in older adults at risk for dementia. There is a need for scalable, automated measures that can constantly monitor and reliably detect mental fatigue during CCT. Here, we develop and validate a novel Recurrent Video Transformer (RVT) method for monitoring real-time mental fatigue in older adults with mild cognitive impairment using their video-recorded facial gestures during CCT. The RVT model achieved the highest balanced accuracy (79.58%) and precision (0.82) compared to the prior models for binary and multi-class classification of mental fatigue. We also validated our model by significantly relating to reaction time across CCT tasks (Waldχ2=5.16,p=0.023). By leveraging dynamic temporal information, the RVT model demonstrates the potential to accurately measure real-time mental fatigue, laying the foundation for future CCT research aiming to enhance effective engagement by timely prevention of mental fatigue.
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  • 文章类型: Journal Article
    本研究从在英语职业和半职业足球中担任与维护和福利有关的角色的各种人员的角度探讨了对虐待的理解。
    通过社会建构主义的立场,本研究能够探索足球虐待的多种理解和看法。个人半结构化访谈(MDuration=68.00分钟,SD=9.05分钟)是由19名参与者在联赛结构中工作进行的,从英超联赛(EPL)到英格兰北部英超联赛甲级联赛,以及与英国职业足球一些主要组织合作的个人。
    通过反身主题分析,强调了三个总体维度:“目前对足球虐待的理解,“”虐待的成分,“和”虐待的体征和症状。“那些以保护能力工作的人的调查结果反映了围绕理解虐待成分的研究文献,但也证明了足球环境对不法行为的细微差别,因为某些形式的虐待是由这种环境的独特性质驱动的。
    从应用的角度来看,研究结果还概述了如何区分虐待的更公开和更隐蔽的迹象和症状,同时也强调了虐待对个人心理健康和自我意识的影响。总的来说,这些发现为从业者和研究人员在设计保障和福利提供时提供了一个考虑的平台,强调需要提高对虐待的知识和认识,同时进行干预以挑战职业足球中普遍存在的工作场所文化。
    UNASSIGNED: This study explored the understanding of maltreatment from the perspective of various personnel working in roles related to safeguarding and welfare in English professional and semi-professional football.
    UNASSIGNED: Through a social constructivist position, the present study was able to explore multiple understandings and perceptions of maltreatment in football. Individual semi-structured interviews (MDuration = 68.00 minutes, SD = 9.05 minutes) were conducted with 19 participants working across league structures ranging from the English Premier League (EPL) to the English Northern Premier League Division One, as well as individuals working with some of the principal organizations in English professional football.
    UNASSIGNED: Through reflexive thematic analysis, three general dimensions were highlighted: \"current understanding of maltreatment in football,\" \"constituents of maltreatment,\" and \"signs and symptoms of maltreatment.\" Findings from those working in a safeguarding capacity mirror the research literature around understanding the components of maltreatment but also demonstrate how wrongdoing is nuanced by the football context, in that certain forms of maltreatment are driven by the unique nature of this environment.
    UNASSIGNED: From an applied perspective, the findings also outline how to distinguish both the more overt and covert signs and symptoms of maltreatment, whilst also highlighting the impact of maltreatment on individuals\' mental health and their sense of self. Overall, the findings provide a platform for practitioners and researchers to consider in the design of safeguarding and welfare provision by highlighting the need to raise knowledge and awareness of maltreatment whilst intervening to challenge the prevailing workplace culture within professional football.
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  • 文章类型: Journal Article
    护理的级联,通常用于评估艾滋病毒和丙型肝炎(HCV)卫生服务的提供,在捕捉个人参与模式的复杂性方面有局限性。这项研究检查了HIV和HCV感染者的参与和死亡轨迹的动态性质。
    我们使用了来自加拿大HIV-HCV共感染队列的数据,前瞻性跟踪来自18个中心的2098名参与者,每两年一次。马尔可夫多状态模型用于评估与以下状态之间过渡相关的社会人口统计学和临床因素:(1)失访(LTFU),定义为18个月没有访问;(2)重新参与(LTFU后重新进入队列);(3)退出研究(即,移动);(4)死亡;否则仍然(5)从事护理。
    从2003年到2022年,共有1809名参与者符合资格标准,并贡献了12591人年。LTFU很常见,46%的人至少经历过1次发作,其中只有57%的人重新参与。五分之一(n=383)的参与者在研究期间死亡。过渡到LTFU的参与者死亡的可能性是一贯参与的参与者的两倍。与过渡到LTFU相关的因素包括可检测的HCVRNA(调整后的危险比[aHR],1.37;95%置信区间[CI],1.13-1.67),HCV治疗的证据,但没有持续的病毒学应答结果(AHR,1.99;95%CI,1.56-2.53),和最近的监禁(AHR,1.94;95%CI,1.58-2.40)。在所有参与轨迹中,土著是死亡的重要预测指标。
    脱离临床护理很常见,并导致更高的死亡率。LTFU人群更有可能需要HCV治疗,突出了消除策略的优先人群。
    UNASSIGNED: The cascade of care, commonly used to assess HIV and hepatitis C (HCV) health service delivery, has limitations in capturing the complexity of individuals\' engagement patterns. This study examines the dynamic nature of engagement and mortality trajectories among people with HIV and HCV.
    UNASSIGNED: We used data from the Canadian HIV-HCV Co-Infection Cohort, which prospectively follows 2098 participants from 18 centers biannually. Markov multistate models were used to evaluate sociodemographic and clinical factors associated with transitioning between the following states: (1) lost-to-follow-up (LTFU), defined as no visit for 18 months; (2) reengaged (reentry into cohort after being LTFU); (3) withdrawn from the study (ie, moved); (4) death; otherwise remained (5) engaged-in-care.
    UNASSIGNED: A total of 1809 participants met the eligibility criteria and contributed 12 591 person-years from 2003 to 2022. LTFU was common, with 46% experiencing at least 1 episode, of whom only 57% reengaged. One in 5 (n = 383) participants died during the study. Participants who transitioned to LTFU were twice as likely to die as those who were consistently engaged. Factors associated with transitioning to LTFU included detectable HCV RNA (adjusted hazards ratio [aHR], 1.37; 95% confidence interval [CI], 1.13-1.67), evidence of HCV treatment but no sustained virologic response result (aHR, 1.99; 95% CI, 1.56-2.53), and recent incarceration (aHR, 1.94; 95% CI, 1.58-2.40). Being Indigenous was a significant predictor of death across all engagement trajectories.
    UNASSIGNED: Disengagement from clinical care was common and resulted in higher death rates. People LTFU were more likely to require HCV treatment highlighting a priority population for elimination strategies.
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  • 文章类型: Journal Article
    由于COVID-19,药剂师已经面临各种危险,这些危险对他们的心理健康产生影响。这项研究强调了COVID-19和工作的影响导致了他们的倦怠。因此,有必要提供心理健康服务。
    评估COVID-19对药学专业人员工作的影响,并确定倦怠对尼泊尔一线卫生提供者药剂师心理健康的影响程度。
    来自尼泊尔第2、3和5省的药剂师参加了一项自我管理的问卷,该问卷使用16项OLBI评估了心理健康,幸福感和倦怠。数据收集自2023年1月至2023年3月。独立样本t检验,单向方差分析,皮尔森的相关性,和线性回归用于确定倦怠与心理健康和福祉之间的任何重要联系。
    在243名参与者中,发现COVID-19大流行和工作对33.7%的药剂师的心理健康和福祉产生负面影响。参与者报告有41.6%的案例有财务问题,9.5%的人考虑离开该行业,并担心服务质量的提供和工作中的错误。在疲惫之间观察到了很强和有意义的正相关关系和线性回归,脱离接触,倦怠,心理健康和幸福。在医院环境中兼职工作的药剂师(p<0.050)由于培训不足而经历了倦怠,延长工作时间,工作上和工作下的压力。
    药剂师应优先考虑健康的工作与生活平衡,其中包括避免>8小时的长时间轮班,定期进行体育锻炼,并促进同事之间的公开交流,以解决工作场所的问题。
    UNASSIGNED: Due to COVID-19, pharmacists have been exposed to a variety of dangers that have an impact on their mental health. The study highlights that impact of COVID-19 and work led to burnout among them. Thus, it is necessary to offer mental health services.
    UNASSIGNED: To assess the impact of COVID-19 on the work of pharmacy professionals and ascertain the extent of the influence of burnout on mental health among pharmacists working as frontline health providers in Nepal.
    UNASSIGNED: Pharmacists from Province 2, 3, and 5 in Nepal participated in a self-administered questionnaire that assessed mental health and wellbeing and burnout using 16-item OLBI. Data was collected from January 2023-March 2023. Independent sample t-test, one-way ANOVA, Pearson\'s correlation, and linear regression were employed to identify any significant connections between burnout and mental health and wellbeing.
    UNASSIGNED: Out of 243 participants, COVID-19 pandemic and work was found to have a negative impact on the mental health and wellbeing of a 33.7% of pharmacists. Participants reported having financial issues in 41.6% of cases and 9.5% considered leaving the profession and were concerned about the provision of service quality and making mistakes at work. A strong and meaningful positive relationship and linear regression were observed between exhaustion, disengagement, burnout, mental health and wellbeing. Pharmacists working part-time (p < 0.050) in hospital settings experienced burnout as a result of insufficient training, extended working hours, and stress both on and off the job.
    UNASSIGNED: Pharmacists are to prioritize a healthy work-life balance, which includes avoiding prolonged shifts >8 h, regular physical exercise and promote open communication among colleagues to address workplace concerns.
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  • 文章类型: Journal Article
    背景:脱离抗逆转录病毒疗法(ART)护理是HIV感染者无法实现病毒载量抑制的重要原因。
    方法:我们搜索了2015年1月至2022年12月的两个数据库和会议摘要,以寻找报告脱离ART护理原因的研究。我们包括在采用“治疗所有”或“选项B+”政策后进行的定量(主要是调查)和定性(深入访谈或焦点小组)研究。我们使用归纳方法对原因进行分类:我们报告研究中报告原因的频率,并为原因开发了概念框架。
    结果:我们确定了21项研究,这些研究报告了“全面治疗”时代脱离ART护理的原因,主要在非洲国家:对艾滋病毒感染者的一般人群进行了六项研究,9名孕妇或产后妇女,6名选定人群(吸毒人群各一名,与世隔绝的土著社区,男人,女人,青少年和与男性发生性关系的男性)。报告的原因是:副作用或其他抗逆转录病毒片剂问题(15项研究);缺乏ART的感知益处(13项研究);心理,心理健康或药物使用(13项研究);对耻辱或保密的担忧(14项研究);缺乏社会或家庭支持(12项研究);社会经济原因(16项研究);与医疗机构相关的原因(11项研究);以及急性近端事件,如意外活动(12项研究)。脱离接触的最常见原因是意外事件,社会经济原因,ART副作用或缺乏ART的感知益处。概念上,研究描述了潜在的脆弱性因素(个体,人际关系,结构和医疗保健),但通常意外的近端事件(例如意外的移动性)是脱离接触发生的触发因素。
    结论:人们脱离了对个人的ART护理,人际关系,结构和医疗保健原因,这些原因相互重叠和相互作用。虽然艾滋病毒方案无法预测和解决可能导致脱离接触的所有事件,一种认识到这种冲击将会发生的方法可能会有所帮助。
    结论:卫生服务应侧重于通过欢迎ART服务来鼓励客户参与护理的方式,以人为本,更灵活,同时提供依从性干预措施,如咨询和同伴支持。
    BACKGROUND: Disengagement from antiretroviral therapy (ART) care is an important reason why people living with HIV do not achieve viral load suppression become unwell.
    METHODS: We searched two databases and conference abstracts from January 2015 to December 2022 for studies which reported reasons for disengagement from ART care. We included quantitative (mainly surveys) and qualitative (in-depth interviews or focus groups) studies conducted after \"treat all\" or \"Option B+\" policy adoption. We used an inductive approach to categorize reasons: we report how often reasons were reported in studies and developed a conceptual framework for reasons.
    RESULTS: We identified 21 studies which reported reasons for disengaging from ART care in the \"Treat All\" era, mostly in African countries: six studies in the general population of persons living with HIV, nine in pregnant or postpartum women and six in selected populations (one each in people who use drugs, isolated indigenous communities, men, women, adolescents and men who have sex with men). Reasons reported were: side effects or other antiretroviral tablet issues (15 studies); lack of perceived benefit of ART (13 studies); psychological, mental health or drug use (13 studies); concerns about stigma or confidentiality (14 studies); lack of social or family support (12 studies); socio-economic reasons (16 studies); health facility-related reasons (11 studies); and acute proximal events such as unexpected mobility (12 studies). The most common reasons for disengagement were unexpected events, socio-economic reasons, ART side effects or lack of perceived benefit of ART. Conceptually, studies described underlying vulnerability factors (individual, interpersonal, structural and healthcare) but that often unexpected proximal events (e.g. unanticipated mobility) acted as the trigger for disengagement to occur.
    CONCLUSIONS: People disengage from ART care for individual, interpersonal, structural and healthcare reasons, and these reasons overlap and interact with each other. While HIV programmes cannot predict and address all events that may lead to disengagement, an approach that recognizes that such shocks will happen could help.
    CONCLUSIONS: Health services should focus on ways to encourage clients to engage with care by making ART services welcoming, person-centred and more flexible alongside offering adherence interventions, such as counselling and peer support.
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