cystic tumour

  • 文章类型: Journal Article
    尤因肉瘤(ES)是儿童和青少年中第二常见的原发性恶性骨肿瘤。约14.5%的原发性恶性肿瘤发生在骨盆骨,它们的预后通常比四肢或肢端肉瘤差。它通常在放射学扫描中表现出侵略性的特征,但也可能具有不同的放射学特征。在这个系列中,我们描述了罕见的骨盆骨骼尤文肉瘤,影像学上有大的骨外囊性成分,由骨外肿瘤病变中存在充满液体的空间定义,这将其与常规ES的固体性质区分开来。我们报告了3例ES的囊性表现,具有影像学特征,支持诊断由耻骨上支引起的原发性恶性骨肿瘤,并伴有巨大的骨盆内实性和囊性肿块。CT引导下活检可诊断ES,有巨大的骨盆内软组织和囊性成分。这些患者接受了新辅助化疗和质子束治疗,固体成分的大小显着减少,而囊性成分保持相对不变。两名患者接受了肿瘤的手术切除(导航P3内部半骨盆切除术和半骨盆P2/P3切除术,分别),一名患者在治疗期间死亡。在两个接受手术的人中,组织学显示ES的边缘清晰,超过99%的治疗引起的坏死。就作者所知,骨盆ES的这种不寻常的表现在文献中首次被描述为病例系列,特别是关于非典型的骨外囊性改变,随着临床和放射学特征,和他们的治疗。
    Ewing sarcoma (ES) is the second most common primary malignant bone tumour in children and adolescents. About 14.5% of primary malignancies develop in pelvic bones, where they typically have worse prognoses than extremity or acral sarcomas. It usually presents with aggressive features on radiology scans, but may also present with different radiological characteristics. In this series, we describe rare appearances of pelvic skeletal Ewing sarcoma, with large extraosseous cystic component on imaging, defined by the presence of fluid-filled spaces in the extraosseous tumour lesion, which distinguishes it from the solid nature of conventional ES. We report 3 cases of cystic presentation of ES, with imaging features supporting diagnosis of a primary malignant bone tumour arising from the superior pubic ramus with associated massive intrapelvic solid and cystic mass. CT-guided biopsy provided diagnosis of ES, with large intrapelvic soft tissue and cystic component. These patients underwent neo-adjuvant chemotherapy and proton beam therapy with significant reduction in size of the solid components, while the cystic components remained relatively unchanged. Two patients underwent surgical resection of the tumour (navigated P3 internal hemipelvectomy and hemipelvis P2/P3 resection, respectively), and one patient died while on treatment. In both who underwent surgery, histology showed ES with margins clear and more than 99% of treatment-induced necrosis. To the authors\' knowledge, this unusual presentation of pelvic ES is described for the first time in the literature as a case series, with particular reference to atypical extraosseous cystic changes, along with the clinical and radiological characteristics, and their treatment.
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  • 文章类型: Case Reports
    囊性粘液瘤非常罕见。此外,很少有报告评估了构成它们的原因。
    一名73岁的亚裔男子接受骨关节炎术前检查,经胸超声心动图(TTE)显示心内肿块。因此,他被转介到我们部门作进一步评估。他没有与肿瘤和心力衰竭相关的特定症状或家族史。TTE显示32×24mm球形块粘附在左房间隔上。肿块的上部形成为囊性,内部回声低,类似于灯泡。经食道超声心动图显示供血动脉从底部流入囊性部分。此外,两个喷射带从二尖瓣方向的囊性部分排出。冠状动脉造影显示供血动脉,主要由右冠状动脉圆锥支和左回旋支组成,血液从供血动脉流入囊状区域,并向二尖瓣排出。由于活动性,进行了手术切除,组织病理学证实是囊性粘液瘤.
    我们描述了囊性粘液瘤的独特解剖学形成,其中包括肿瘤供血动脉和引流出口血管之间的精确平衡。
    UNASSIGNED: Cystic myxomas are quite rare. Moreover, few reports have evaluated the causes that constituted them.
    UNASSIGNED: A 73-year-old Asian man presented for pre-operative examination of osteoarthritis, and transthoracic echocardiography (TTE) revealed an incidental intracardiac mass. Therefore, he was referred to our department for further evaluation. He had no specific symptoms or family history related to tumours and heart failure. The TTE showed a 32 × 24 mm spherical mass adherent to the left atrial septum. The upper part of the mass was cystic in formation and hypoechoic inside and resembled a light bulb. Transoesophageal echocardiography showed the feeding arteries flowing from the bottom into the cystic part. In addition, two jet strips drained from the cystic part in the direction of the mitral valve. Coronary angiography revealed the feeding arteries, which consisted mainly of the right coronary artery conus branch and the left circumflex branch, and the blood flowed into the saccular area from the feeding arteries and excreted towards the mitral valve. Surgical resection was performed due to the mobility, and the histopathology confirmed a cystic myxoma.
    UNASSIGNED: We described the unique anatomical formation of a cystic myxoma, which consisted of an exquisite balance between the tumour-feeding arteries and the draining outlet vessels.
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  • 文章类型: Case Reports
    未经证实:腹腔镜恶性肿瘤手术偶尔会导致套管针插入部位复发或端口部位转移(PSM)。我们报告了一名需要紧急腹腔镜手术治疗卵巢肿瘤的患者,并回顾了相关文献。
    UNASSIGNED:一名42岁的妇女因怀疑卵巢囊性肿瘤破裂而突然出现腹痛,并接受了腹腔镜右附件切除术。术后组织学诊断为黏液性交界性卵巢肿瘤;然而,初次手术后8个月在港口发现未分化癌.端口部位腹壁肿瘤的组织病理学诊断与术中病理结果不同,这与PSM定义相矛盾。术后,她接受了三个全身化疗疗程,但死于肿瘤转移。
    UNASSIGNED:这是一个非典型的PSM病例,与最初的肿瘤有组织病理学差异。在这种情况下,仔细的术前诊断和术中注意至关重要。
    UNASSIGNED: Laparoscopic surgery for malignant tumours occasionally results in recurrence at the trocar insertion site or port-site metastasis (PSM). We report on a patient requiring emergency laparoscopic surgery for an ovarian tumour with a review of the relevant literature.
    UNASSIGNED: A 42-year-old woman developed sudden abdominal pain and underwent laparoscopic right adnexectomy because of a suspected ovarian cystic tumour rupture. The postoperative histological diagnosis was a mucinous borderline ovarian tumour; however, an undifferentiated carcinoma was detected at the port site eight months after the initial surgery. The histopathological diagnosis of the abdominal wall tumour at the port site differed from intraoperative pathological findings, which was contradictory to PSM definition. Postoperatively, she received three systemic chemotherapy courses but died consequent to tumour metastasis.
    UNASSIGNED: This is an atypical PSM case with histopathological differences from the initial tumour. Careful preoperative diagnosis and intraoperative attention are essential in such cases.
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  • 文章类型: Journal Article
    促纤维化婴儿星形细胞瘤和神经节胶质瘤(DIA/DIG)通常表现为大尺寸,大的囊性成分,大型硬脑膜植入物,大型船只的包裹,18个月内的临床表现,癫痫发作发生率高,总体预后良好,即使肿瘤手术在第一次手术时可能非常具有挑战性。
    我们回顾性回顾了2008年至2019年间接受手术治疗的被诊断患有促纤维增生性婴儿肿瘤的患者的临床和放射学数据。
    该系列包括12名患者。手术时的中位年龄为91天。平均肿瘤体积为212cm3。囊性成分主要在0至295cm3之间。5例术前明显活动性脑积水。八名患者(66.6%)接受了全部或小计切除,其中三人(25%)接受了部分切除,1例患者(8.3%)接受活检。一名患者因严重低血压在术后24小时内死亡,作为术中大量失血的结果。总的来说,第一次手术后,有7例(58.3%)患者对肿瘤进行了再次手术:4例患者进行了两次手术;3例患者进行了3次手术。两名患者进行了远程定位并接受了化疗。在最后的随访中,7例患者无瘤,2患有稳定的疾病,和2患有进行性疾病(软脑膜播种)。
    促增生性婴儿肿瘤是罕见的巨大新生儿肿瘤。完全去除是治疗的目标,但即使不能完全切除,预后仍然良好。如果肿瘤进展或残留肿瘤引起癫痫,重新操作是第一种选择,化疗保留给不可切除或传播的病例,结果不一,while,到目前为止,放射治疗仍然不起作用。
    Desmoplastic infantile astrocytomas and gangliogliomas (DIA/DIG) usually present with a large size, large cystic component, large dural implant, encasement of big vessels, clinical presentation within 18 months of life, high incidence of seizures and overall good prognosis, even if tumour surgery can be very challenging at first procedure.
    We retrospectively reviewed clinical and radiological data of patients diagnosed with desmoplastic infantile tumours who were surgically treated between 2008 and 2019.
    The series included 12 patients. The median age at surgery was 91 days. The average tumour volume was 212 cm3. Cystic components were predominant ranging from 0 to 295 cm3. Active hydrocephalus was pre-operatively evident in 5 cases. Eight patients (66.6%) received total or subtotal removal, three of them (25%) underwent partial removal, and one patient (8.3%) received a biopsy. One patient died within 24 h after surgery due to severe hypotension, as a consequence of significant intraoperative blood loss. Overall, seven (58.3%) patients were reoperated on the tumour after the first procedure: 4 patients were operated twice; 3 patients were operated 3 times. Two patients presented remote localizations and underwent chemotherapy. At last follow-up, 7 patients were tumour-free, 2 are alive with stable disease, and 2 are alive with progressive disease (leptomeningeal seeding).
    Desmoplastic infantile tumours are rare giant neonatal tumours. Total removal is the goal of treatment, but prognosis remains good even if total removal is not achieved. In case of tumour progression or epilepsy from residual tumour, reoperation is the first option, with chemotherapy reserved to unresectable or disseminated cases with mixed results, while, to date, radiotherapy still plays no role.
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    文章类型: Case Reports
    Impacted teeth are one of causes of patients visits to maxillofacial surgeons or dental surgeons. They are often detected accidentally when diagnosing other diseases in area of the nose, paranasal sinuses or oral cavity. This paper presents the process of diagnostics and treatment of a rare case of a 53-year-old patient, who developed hard palate abscess as a result of caries of impacted tooth accompanied by lateral periodontal cyst and nasopalatine fistula located in jaw.
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  • 文章类型: Journal Article
    背景:产生粘蛋白的肝囊性肿瘤(MHCN)并不常见,并且可能是恶性的。方法:在我们中心发现了9例MHCN,时间超过32年。临床患者,生物,回顾了放射学和病理学特征。病变分为黏液性囊性肿瘤(MCN)和胆管导管内乳头状肿瘤(IPNB)(WHO2010分类)。结果:共审查了5个MCN和4个IPNB。血清和囊内肿瘤标志物不足以诊断恶性肿瘤。9名患者中有5名(56%)出现并发症,平均症状持续时间为26个月(范围:1-132)。三名患者在转诊前管理不善。放射学特征使9名患者中有8名(89%)能够进行术前诊断。更大的肿瘤大小,单眼病变和壁结节提示恶性肿瘤。八名患者实现了根治性肿瘤切除。1例IPNB患者被误诊并进行了去顶。103个月的中位随访,6名良性肿瘤患者中有5人活着,没有病,而误诊的IPNB在7年后复发并伴有致命性恶性转化。在三名恶性肿瘤患者中(中位随访时间:77个月),两名IPNB死亡,一个来自癌症复发,一个来自无关的原因,而恶性MCN是活的和无病的。结论:适当的MHCN诊断至关重要,然而,它经常被误诊和管理不善。完全切除后的预后良好。
    Background: Mucin-producing hepatic cystic neoplasms (MHCN) are uncommon and potentially malignant.Methods: Nine MHCN were encountered in our centre for over 32 years. Patients\' clinical, biological, radiological and pathological features were reviewed. Lesions were classified into Mucinous Cystic Neoplasms (MCN) and Intraductal Papillary Neoplasms of the Bile duct (IPNB) (WHO 2010 classification).Results: Five MCN and 4 IPNB were reviewed. Serum and intracystic tumour markers were insufficient to diagnose malignancy. Complications were encountered in five out of nine patients (56%), mean symptom duration was 26 months (range: 1-132). Three patients were mismanaged pre-referral. Radiological features enabled preoperative diagnosis in eight out of nine patients (89%). Greater tumour size, unilocular lesion and mural nodularity indicated malignancy. Radical tumour excision was achieved in eight patients. One IPNB patient was misdiagnosed and underwent unroofing. For 103 months median follow-up, five out of six patients with benign tumours were alive and disease-free, whereas the misdiagnosed IPNB recurred with fatal malignant transformation seven years later. Among the three patients with malignancies (median follow-up: 77 months), two IPNB died, one from cancer recurrence and one from unrelated causes, whereas the malignant MCN was alive and disease-free.Conclusions: Appropriate MHCN diagnosis is crucial, yet it is often misdiagnosed and mismanaged. The prognosis after complete excision is favourable.
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  • 文章类型: Evaluation Study
    目的:评估机器人辅助肾部分切除术(RAPN)在囊性肿瘤中的疗效,分析一个大的,多机构,RAPN回顾性系列,由于关于囊性肿瘤中RPN结局的可用数据有限。
    方法:我们评估了2010年至2013年接受RAPN治疗囊性或实体肿瘤的465例患者,回顾性Vattikuti机器人泌尿外科全球质量倡议(GQI-RUS)数据库。单变量和多变量线性和逻辑回归模型解决了囊性肿瘤与围手术期结果的关联。
    结果:总而言之,54(12%)肿瘤是囊性的。囊性肿瘤与手术时间显著缩短相关(t-3.9;P<0.001),一旦根据协变量的影响进行了调整,而失血和热缺血时间相似。术后任何级别的并发症记录在66个实体(16%)和9个囊性(17%)肿瘤中(P=0.08)。在多变量分析中,囊性肿瘤与任何级别的术后并发症的风险显著降低无关[比值比(OR)0.9;P=0.8].同样,具有囊性特征的肿瘤的存在与高级别术后并发症的风险无显著差异(OR2.2;P=0.1).囊性和实体肿瘤的癌症组织学患病率和手术切缘阳性率相似。囊性肿瘤与术后估计肾小球滤过率无显著差异(t0.4;P=0.7),一旦调整了协变量的影响。
    结论:RAPN可用于围手术期的囊性肾肿瘤,病态,和功能结果类似于实体瘤可实现的结果。
    OBJECTIVE: To evaluate the outcomes of robot-assisted partial nephrectomy (RAPN) in cystic tumours, analysing a large, multi-institutional, retrospective series of RAPN, as limited data are available about the outcome of RAPN in cystic tumours.
    METHODS: We evaluated 465 patients who received RAPN for either cystic or solid tumours from 2010 to 2013 and included in the multi-institutional, retrospective Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database. Univariable and multivariable linear and logistic regression models addressed the association of cystic tumours with perioperative outcomes.
    RESULTS: In all, 54 (12%) tumours were cystic. Cystic tumours were associated with significantly lower operative time (t -3.9; P < 0.001), once adjusted for the effect of covariates, whereas blood loss and warm ischaemia time were similar. Postoperative any grade complications were recorded in 66 solid (16%) and nine cystic (17%) tumours (P = 0.08). In multivariable analysis, cystic tumours were not associated with a significantly lower risk of any grade postoperative complications [odds ratio (OR) 0.9; P = 0.8]. Similarly, presence of tumours with cystic features was not associated with a significantly different risk of high-grade postoperative complications (OR 2.2; P = 0.1). Prevalence of cancer histology and positive surgical margin rates were similar in cystic and solid tumours. Cystic tumours were not associated with significantly different postoperative estimated glomerular filtration rate (t 0.4; P = 0.7), once adjusted for the effect of covariates.
    CONCLUSIONS: RAPN can be performed in cystic renal tumours with perioperative, pathological, and functional outcomes similar to those achievable in solid tumours.
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  • DOI:
    文章类型: Case Reports
    The authors present a case of a left gigantic supraclavicular and lateralcervical tumor with rapid growth, which has turned out to be a subdeltoideus bursitis.
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  • 文章类型: Case Reports
    Teratomas are germ cell tumours arising as the result of abnormal development of totipotential cells. They are commonly encountered in the gonads and occasionally found in mediastinum. We report a case of asymptomatic 28 years old lady with concomitant mature cystic teratoma in her mediastinum and left ovary which was diagnosed incidentally during health check up. This case is reported because of its rare and unusual coexistence.
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