抗生素耐药性的巨大增加和新抗生素的有限范围，有效的抗生素是我们应该思考合理的抗感染治疗方法的原因。在临床实践中，经常发现在治疗危重病人的同时过度使用抗生素。抗生素治疗通常是经验性的，或者它只是基于治疗上的犹豫不决，不仅仅是ICU患者。在取样进行微生物分析之前施用抗生素,或者没有基于实验室发现的治疗调整。解决方案在于抗生素管理，这是确保抗生素在未来几年内足够有效的方法。
The enormous increase in antibiotic resistance and the limited spectrum of new, effective antibiotics are the reasons why we should think about a rational approach to anti-infective therapy. The excessive and non-indicated use of antibiotics while treating critically ill patients can be found quite often in clinical practice. Antibiotic therapy is usually indicated empirically, or it is only based on therapeutic indecision, not just in ICU patients. The antibiotics are administered before taking a sample for microbiological analysis or there is no therapy adjustment based on the laboratory findings. The solution lies in antibiotic stewardship, which is the way to ensure that antibiotics will be sufficiently effective in years to come.
