为了开发和验证牛津髋关节评分(OHS)和HOOS-12汇总影响评分之间的双向人行横道,在牛津膝关节评分(OKS)和KOOS-12综合影响评分之间。
数据来自澳大利亚骨科协会国家关节置换登记患者报告结果测量项目。分析中包括接受OHS和HOOS-12或OKS和KOOS-12器械的骨关节炎初次关节置换的患者。使用等百分位法创建四个人行横道,在相等之前,使用对数线性模型平滑了分数的分布。通过比较实际分数和派生分数来评估交叉有效性,皮尔逊相关系数,均方根误差(RMSE)和Bland-Altman图。
配对的OHS/HOOS-12数据和配对的OKS/KOOS-12数据可用于4,513例接受全髋关节置换的患者和5,942例接受全膝关节置换的患者,分别。在实际和人行横道得出的平均得分之间观察到最小差异(实际OHS27.55与得出的OHS27.56;实际HOOS-1253.28与得出的HOOS-1253.31;实际OKS27.34与得出的OKS27.34;实际KOOS-1250.51与得出的KOOS-1250.58)。在实际得分和派生得分之间观察到高度相关性(髋关节专用器械的皮尔森r:0.943-0.946;膝关节专用器械的皮尔森r:0.925-0.931)。绘制的实际与平均值得出的分数也表明在仪器量表的宽度上具有很强的一致性。
这些人行横道提供了实际OHS的近似,OKS,HOOS-12和KOOS-12得分,如多个验证指标所示。他们为临床医生提供资源,研究人员和关节成形术登记处,以支持PROMs评分转换和数据协调工作。
To develop and validate bi-directional
crosswalks between the Oxford Hip Score (OHS) and HOOS-12 summary impact score, and between the Oxford Knee Score (OKS) and KOOS-12 summary impact score.
Data were sourced from the Australian Orthopaedic Association National Joint Replacement Registry Patient-Reported Outcome Measures Program. Patients undergoing primary joint replacement for osteoarthritis who completed the OHS and HOOS-12 or OKS and KOOS-12 instruments were included in the analysis. An equipercentile method was used to create four
crosswalks, with the distribution of scores smoothed using log-linear models prior to equating. Crosswalk validity was assessed through comparison of actual vs derived scores, Pearson correlation coefficients, root mean square errors (RMSE) and Bland-Altman plots.
Paired OHS/HOOS-12 data and paired OKS/KOOS-12 data were available for 4,513 patients undergoing total hip replacement and 5,942 patients undergoing total knee replacement, respectively. Minimal differences were observed between actual and crosswalk-derived mean scores (actual OHS 27.55 vs derived OHS 27.56; actual HOOS-12 53.28 vs derived HOOS-12 53.31; actual OKS 27.34 vs derived OKS 27.34; actual KOOS-12 50.51 vs derived KOOS-12 50.58). High correlation was observed between actual and derived scores (Pearson\'s r for hip-specific instruments: 0.943-0.946; Pearson\'s r for knee-specific instruments: 0.925-0.931). Plotted actual vs mean derived scores also indicated robust concordance across the breadth of the instrument scales.
These
crosswalks provide close approximations of actual OHS, OKS, HOOS-12 and KOOS-12 scores, as indicated by multiple validation metrics. They offer a resource for clinicians, researchers and arthroplasty registries to support PROMs score conversion and data harmonisation efforts.