corticosteroid side effects

  • 文章类型: Journal Article
    皮质类固醇是抗炎药,用于减少炎症和抑制各种疾病的免疫系统,包括过敏,哮喘,系统性红斑狼疮,湿疹,炎症性肠病,和肿胀的关节或肌肉。这项研究的目的是评估沙特阿拉伯普通人群中有关皮质类固醇副作用的意识水平和信息来源。
    这项观察性横断面研究是在沙特阿拉伯使用电子问卷进行的。使用了非概率便利抽样技术。社会科学统计软件包(SPSS)用于数据分析。
    该研究包括来自沙特阿拉伯的755名参与者(67.3%的女性和32.7%的男性)。大约26.8%的人报告使用皮质类固醇,73.9%的人知道糖皮质激素的副作用。在类固醇使用者(202名参与者)中,最常见的情况是过敏(36.1%),哮喘或慢性阻塞性肺疾病(COPD)(21.8%),和皮肤病(27.7%)。大多数受访者(57.9%)使用类固醇少于2周,最常见的形式是局部应用(52.5%)。只有30.7%的人在处方时收到了有关副作用的信息。报道最多的副作用是躯干肥胖,月亮的脸,皮肤变薄,瘀伤,伤口愈合较慢。
    这项研究强调了在沙特阿拉伯提高对皮质类固醇副作用的认识和知识的重要性。虽然总体认识水平相对令人满意,具体的副作用需要在教育工作中进一步关注。
    UNASSIGNED: Corticosteroids are anti-inflammatory medications that are used to reduce inflammation and inhibit the immune system in a variety of disorders, including allergies, asthma, systemic lupus erythematous, eczema, inflammatory bowel disease, and swollen joints or muscles. The goal of this study was to assess the level of awareness and sources of information about the side effects of corticosteroids among the general population in Saudi Arabia.
    UNASSIGNED: This observational cross-sectional study was conducted in Saudi Arabia using an electronic questionnaire. A non-probability convenience sampling technique was used. Statistical Package for the Social Sciences (SPSS) was used for data analysis.
    UNASSIGNED: The study included 755 participants from Saudi Arabia (67.3% females and 32.7% males). Around 26.8% reported using corticosteroids, and 73.9% were aware of the side effects of glucocorticoids. Among steroid users (202 participants), the most common conditions were allergies (36.1%), asthma or chronic obstructive pulmonary disease (COPD) (21.8%), and skin diseases (27.7%). The majority of respondents (57.9%) used steroids for less than 2 weeks, and topical application (52.5%) was the most common form. Only 30.7% received information about side effects at the time of prescription. The most reported side effects were truncal obesity, moon face, skin thinning, bruising, and slower wound healing.
    UNASSIGNED: This study highlights the importance of promoting awareness and knowledge regarding the side effects of corticosteroids in Saudi Arabia. While overall awareness levels were relatively satisfactory, specific side effects require further attention in educational efforts.
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  • 文章类型: Case Reports
    皮质类固醇诱发的肌病是最常见的药物诱发的肌病,可能在治疗以皮质类固醇为主要治疗手段的疾病期间出现。我们介绍了一个临床病例,患者接受皮质类固醇治疗,表现为近端肌无力,肌痛,肌肉酶显著升高,和横纹肌溶解引起的急性肾损伤。只有通过肌肉活检才能明确诊断。
    Corticosteroid-induced myopathy is the most common drug-induced myopathy and could appear during the treatment of diseases where corticosteroids are the mainstay of treatment. We present a clinical case of a patient treated with corticosteroids who presented with proximal muscle weakness, myalgias, marked elevation of muscle enzymes, and acute kidney injury due to rhabdomyolysis. The definitive diagnosis was only possible through a muscle biopsy.
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