coronary artery bypass grafting(cabg)

冠状动脉旁路移植术 (cabg)
  • 文章类型: Case Reports
    大动脉炎(TA)是一种罕见的大血管动脉炎,主要影响主动脉及其主要分支。这种炎症导致增厚,纤维化,动脉壁狭窄,这可能导致血栓形成。所产生的症状通常是由于末端器官的缺血。冠状动脉受累并不常见,主要影响动脉口。冠状动脉的口受累可以有一个戏剧性的过程,包括致命的结果。我们介绍了一名16岁女性的TA累及左冠状动脉主干口的病例,导致严重狭窄.在左主干动脉上成功进行经皮冠状动脉介入治疗,并放置了通气管支架,7个月后,由于突出支架近端开口完全血栓形成,心脏骤停并发。
    Takayasu arteritis (TA) is a rare form of large vessel arteritis that predominantly affects the aorta and its major branches. This inflammation leads to thickening, fibrosis, and stenosis of the arterial walls, which may lead to thrombus formation. The resulting symptoms are typically due to ischemia of the end organs. Coronary artery involvement is uncommon and primarily affects the ostia of the arteries. Ostial involvement of the coronary arteries can have a dramatic course, including fatal outcomes. We present the case of a 16-year-old female with TA involving the ostium of the left main coronary artery, causing severe stenosis. A successful percutaneous coronary intervention was performed on the left main artery with snorkel stent placement, which was complicated by cardiac arrest seven months later due to complete thrombosis of the proximal opening of the protruding stent.
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  • 文章类型: Case Reports
    由于免疫球蛋白G4(IgG4)相关疾病(IgG4-RD)引起的冠状动脉瘤(CAA)相对罕见,治疗方法的选择没有共识。在本研究中,我们报告了IgG4-RD引起的多个巨大CAAs的手术治疗结果。一名71岁的男子被诊断为严重的主动脉瓣反流和CAA。血液检查显示IgG4水平很高,计算机断层扫描显示四个巨大的冠状动脉瘤:两个在右冠状动脉(RCA)(近端RCA和后降支(PDA)),一个在左前降支(LAD),和一个在对角分支(Dx)。我们计划进行主动脉瓣置换术,冠状动脉瘤切除术,冠状动脉旁路移植术(CABG)。主动脉瓣置换术后,近端RCA的CAA,LAD,Dx被切除。用心包牛补片和结扎封闭动脉瘤的近端和远端。然而,由于远端PDA钙化太多,无法吻合,PDA动脉瘤比其他动脉瘤小,决定离开PDA动脉瘤.SVG-RCA和Dx的吻合,以及左胸内动脉到LAD,被执行了。动脉瘤壁的组织病理学检查显示高IgG4阳性细胞/IgG阳性细胞比率,并诊断为IgG4-RD。在治疗因IgG4-RD引起的CAAs时,选择一个考虑到大小的程序是至关重要的,location,和动脉瘤的性质,和合并症。为了确保切除动脉瘤和阻断血流,用心包牛补片和CABG封闭流入和流出道是有效的。
    Coronary artery aneurysms (CAAs) due to an immunoglobulin G4 (IgG4)-related disease (IgG4-RD) are relatively rare, and there is no consensus on the choice of treatment method. In the present study, we report the results of the surgical treatment for multiple giant CAAs caused by IgG4-RD. A 71-year-old man was diagnosed with severe aortic regurgitation and CAAs. A blood test showed high IgG4 levels, and computed tomography revealed four giant coronary artery aneurysms: two in the right coronary artery (RCA) (proximal RCA and posterior descending artery (PDA)), one in the left anterior descending (LAD), and one in the diagonal branch (Dx). We planned aortic valve replacement, coronary aneurysm resection, and coronary artery bypass grafting (CABG). After finishing aortic valve replacement, the CAAs in proximal RCA, LAD, and Dx were resected. The proximal and distal tracts of the aneurysm were closed with a pericardial bovine patch and ligation. However, since the distal PDA was too calcified to be anastomosed, and the PDA aneurysm was smaller than the others, it was decided to leave the PDA aneurysm. The anastomoses of SVG-RCA and Dx, as well as the left internal thoracic artery to LAD, were performed. Histopathological examination of the aneurysm wall showed a high IgG4-positive cell/IgG-positive cell ratio, and a diagnosis of IgG4-RD was made. In the treatment of CAAs due to IgG4-RD, it is essential to select a procedure that takes into account the size, location, and nature of the aneurysm, and comorbidities. To ensure resection of the aneurysm and blockade of blood flow, closure of the inflow and outflow tracts with a pericardial bovine patch and CABG are effective.
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  • 文章类型: Case Reports
    转甲状腺素蛋白心脏淀粉样变性(ATTR-CA)是一种以心肌中错误折叠的转甲状腺素蛋白在细胞外沉积为特征的疾病,由于临床表现多样和非特异性,历史上难以诊断。可变心电图(ECG)和超声心动图检查结果。无创心脏成像的进步导致ATTR-CA的诊断显着增加。曾经被认为是一种罕见的疾病,越来越多的证据表明ATTR-CA比以前理解的更普遍,提示需要早期诊断和干预。我们概述了一名78岁的男性因胸部不适出现在急诊科的情况,呼吸急促,头晕,和出汗。他被发现患有严重的冠状动脉疾病(CAD)和间歇性完全性心脏传导阻滞。心脏功能障碍无法通过经皮冠状动脉介入治疗(PCI)解决,因此患者被转诊为冠状动脉旁路移植术(CABG)。术中,患者的心脏被发现异常增厚和纤维化。心脏组织活检和使用99m焦磷酸盐闪烁显像进行评估,单光子发射计算机断层扫描,液相色谱-串联质谱显示ATTR-CA。需要快速且低成本的筛查工具以允许疾病的早期识别。心脏淀粉样变性的诊断线索包括腕管综合征的存在,腰椎管狭窄症,心房颤动,射血分数保留的难治性心力衰竭,左心室壁增厚.考虑到这些危险信号的症状,在老年患者中,即使在急性环境中出现ATTR心脏淀粉样变性,临床医师也应该有更高的怀疑指数.
    Transthyretin cardiac amyloidosis (ATTR-CA) is a condition characterized by extracellular deposition of misfolded transthyretin proteins in the myocardium and has been historically difficult to diagnose due to diverse clinical manifestations and nonspecific, variable electrocardiogram (ECG) and echocardiogram findings. Advancements in noninvasive cardiac imaging have led to significant increases in diagnoses of ATTR-CA. Once thought to be a rare condition, there is growing evidence to suggest that ATTR-CA is more prevalent than previously understood, prompting the need for early diagnosis and intervention. We outline the case of a 78-year-old male who presented to the emergency department with chest discomfort, shortness of breath, dizziness, and diaphoresis. He was found to have severe coronary artery disease (CAD) and intermittent complete heart block. Cardiac dysfunction was unable to be resolved by percutaneous coronary intervention (PCI) and thus the patient was referred for coronary artery bypass grafting (CABG). Intraoperatively, the patient\'s heart was found to be abnormally thickened and fibrosed. Biopsy of the cardiac tissue and evaluation using technetium-99m pyrophosphate scintigraphy, single-photon emission computed tomography, and liquid chromatography-tandem mass spectrometry revealed ATTR-CA. There is a need for fast and low-cost screening tools to allow for early identification of the disease. Diagnostic clues for cardiac amyloidosis include the presence of carpal tunnel syndrome, lumbar spinal stenosis, atrial fibrillation, treatment-resistant heart failure with preserved ejection fraction, and a thickened left ventricular wall. Given the presence of these red flag symptoms, clinicians should have a heightened index of suspicion for ATTR cardiac amyloidosis in elderly patients even when presenting in acute settings.
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  • 文章类型: Journal Article
    背景:死亡的主要原因,冠状动脉疾病(CAD)通常需要冠状动脉旁路移植术(CABG)和经皮冠状动脉介入治疗(PCI)等侵入性手术.土著和非土著澳大利亚人的心血管结果各不相同;然而,缺乏对这些差异的全面了解。
    方法:为了比较土著和非土著澳大利亚人的PCI和CABG结果,我们进行了系统评价和荟萃分析.包括10项回顾性观察研究,这些研究检查了死亡率,心血管事件,合并症,和手术成功率。搜索了2014年至2024年的数据库,直接比较澳大利亚土著和非土著人口的研究是纳入标准之一。
    结果:手术后30天内,接受PCI的澳大利亚土著居民合并症发生率较高,长期死亡率和MACE风险较高.同样,CABG术后土著患者的长期死亡率更高.文化安全,社会经济因素,以及影响治疗延误和获得护理的区域因素,所有受影响的差异。对于30天的死亡率,汇总分析显示比值比为1.04(95%CI0.78,1.40),表明没有有意义的差异。不利事件的总赔率比为1.07(95%CI0.86,1.33),这意味着土著群体和没有土著群体之间没有统计学上的显著差异。
    结论:土著澳大利亚人在PCI和CABG手术后的心血管结局仍然更差,即使程序成功率相似。确保土著群体获得公平的心血管结果,针对潜在风险因素的靶向治疗,增加获得文化上适当的护理的机会,减少医疗保健障碍至关重要。
    BACKGROUND: A major cause of death, coronary artery disease (CAD) often necessitates invasive procedures like coronary bypass grafting (CABG) and percutaneous coronary intervention (PCI). Cardiovascular outcomes vary between indigenous and non-indigenous Australian people; however, comprehensive knowledge of these differences is absent.
    METHODS: To compare PCI and CABG results between indigenous and non-indigenous Australians, a systematic review and meta-analysis were carried out. Included were 10 retrospective observational studies that examined mortality, cardiovascular events, comorbidities, and operative success rates. Databases spanning 2014 to 2024 were searched, and research that directly compared Australia\'s indigenous and non-indigenous populations was among the inclusion criteria.
    RESULTS: Within 30 days of surgery, indigenous Australians receiving PCI had greater rates of comorbidities and were at higher risk of long-term mortality and MACE. Similarly, there was a greater long-term death rate among indigenous patients following CABG. Cultural safety, socioeconomic factors, and regional factors affecting treatment delays and access to care all affected disparities. For 30-day mortality, the pooled analysis shows an odds ratio of 1.04 (95% CI 0.78, 1.40), indicating no meaningful difference. The total odds ratio for unfavorable occurrences is 1.07 (95% CI 0.86, 1.33), meaning there is no statistically significant difference between Indigenous groups and those that are not.
    CONCLUSIONS: Indigenous Australians continue to have worse cardiovascular outcomes after PCI and CABG procedures, even with similar procedural success rates. To ensure equitable cardiovascular outcomes for indigenous groups, targeted therapies targeting underlying risk factors, increased access to culturally appropriate care, and decreased obstacles to healthcare access are critical.
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  • 文章类型: Case Reports
    一种罕见的冠状动脉疾病是冠状动脉瘤(CAA)。根据血管造影报告,冠状动脉瘤的发病率从1.5%到4.9%不等,在男性中频率更高。患有冠心病和右冠状动脉(RCA)动脉瘤的患者同时进行了成功的同时冠状动脉搭桥术以及动脉瘤重建手术。
    One kind of coronary artery disease that is uncommon is coronary artery aneurysm (CAA). According to angiographic reports, the incidence of coronary artery aneurysms ranges from 1.5% to 4.9%, with a higher frequency in men. A patient with both coronary heart disease and an aneurysm in the right coronary artery (RCA) underwent a successful simultaneous coronary bypass together with an aneurysmal reconstruction procedure.
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  • 文章类型: Case Reports
    脑卒中是心脏手术的常见并发症,颈动脉狭窄是中风的既定危险因素。因此,正在接受心脏手术的颈动脉狭窄患者需要同时或在心脏手术前对前者进行适当的处理.我们提出了一个具有挑战性的病例,一个67岁的男性患者,他表现为全身无力,严重的主动脉瓣狭窄,和显著的双侧颈动脉狭窄。这些发现的共存引发了关于是否先进行颈动脉内膜切除术或主动脉瓣置换术的争论。此外,过去的经皮冠状动脉介入治疗和冠状动脉旁路移植术的病史使该决定更具挑战性.多种方法已被用于处理与心脏手术并存的颈动脉狭窄;然而,没有明确的指导方针,尤其是冠状动脉旁路移植术以外的手术或颈动脉狭窄为双侧且严重的手术。
    Stroke is a common complication of cardiac surgery, and carotid artery stenosis is an established risk factor for stroke. Therefore, patients with carotid artery stenosis who are undergoing cardiac surgery require proper management of the former either simultaneously or before cardiac surgery. We present a challenging case of a 67-year-old male patient who presented with generalized weakness, severe aortic stenosis, and significant bilateral carotid artery stenosis. The coexistence of these findings sparked a debate about whether to perform a carotid endarterectomy first or an aortic valve replacement. Moreover, a past history of percutaneous coronary intervention and coronary artery bypass grafts made the decision more challenging. Multiple approaches have been employed for the management of coexisting carotid artery stenosis with cardiac surgery; however, no definitive guidelines exist, especially for surgeries other than coronary artery bypass grafts or where the carotid stenosis is bilateral and severe.
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  • 文章类型: Journal Article
    Coronary artery disease (CAD) is a prevalent and possibly fatal cardiovascular ailment, and it is treated surgically by coronary artery bypass grafting (CABG). The coronary arteries, which supply the heart with oxygen and nutrients, are the most commonly affected. Even though CABG is a frequently employed procedure to restore cardiac blood flow, prolonged rehabilitation is necessary for long-term success. For patients with heart disease, cardiac rehabilitation (CR) involves a comprehensive therapeutic approach. It consists of risk mitigation, regular exercise, health education, and efficient stress management. Information and communication technology is used in telerehabilitation (TR), a rehabilitation service that offers a flexible choice that improves self-management. This study examined novel approaches and effective intervention elements while comparing cardiac TR with center-based programs in terms of risk factor management, patient commitment, and satisfaction.
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  • 文章类型: Journal Article
    急性冠状动脉综合征(ACS)是全球主要的死亡原因,强调有效预防的重要性,早期诊断,及时干预。虽然药物对许多患者有好处,血运重建手术,如冠状动脉旁路移植术(CABG),经皮冠状动脉介入治疗(PCI),和新兴的混合方法仍然是ACS管理的关键。这篇综述深入研究了2018年ESC/EACTS指南,并对现有文献进行了分析,以阐明血运重建方法的频谱。虽然CABG和PCI都显示出有希望的结果,两者之间的最佳选择取决于对个体患者因素的全面评估,解剖复杂性由先进的成像指导,合并症,和年龄。决定是否进行罪魁祸首或完全血运重建,以及立即或分阶段的血运重建,取决于各种因素,包括年龄,疾病复杂性,和临床结果。这种基于证据的决策过程是由一个基于正在进行的临床评估的多学科心脏团队精心策划的。本综述的主要目的是为血运重建策略提供有价值的见解,并审查当前指南与该领域最新进展的一致性。
    Acute coronary syndrome (ACS) stands as a leading global cause of mortality, underscoring the importance of effective prevention, early diagnosis, and timely intervention. While medications offer benefits to many patients, revascularization procedures such as coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), and emerging hybrid approaches remain pivotal for ACS management. This review delves into the 2018 ESC/EACTS guidelines alongside an analysis of existing literature to shed light on the spectrum of revascularization methods. While both CABG and PCI demonstrate promising outcomes, the optimal choice between the two hinges on a comprehensive assessment of individual patient factors, anatomical complexity guided by advanced imaging, comorbidities, and age. The determination of whether to pursue culprit or total revascularization, as well as immediate or staged revascularization, is contingent upon various factors, including age, disease complexity, and clinical outcomes. This evidence-based decision-making process is orchestrated by a multidisciplinary heart team grounded in ongoing clinical evaluation. The primary objective of this review is to provide valuable insights into revascularization strategies and scrutinize the congruence of current guidelines with recent advancements in the field.
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  • 文章类型: Case Reports
    冠状动脉旁路移植术(CABG)在治疗阻塞性冠状动脉疾病中起着重要作用,尤其是糖尿病或多血管疾病患者。目前,在美国,据报道,CABG的年发病率约为40万。总的来说,胃肠道(GI)并发症发生在接受心脏直视手术的患者中不到2%。急性结肠假性梗阻,也被称为奥格尔维综合征,是一种以结肠扩张为特征的疾病,其不存在阻碍肠内容物流动的解剖损伤。这种情况发生在心脏手术后的0.06%的患者中,在CABG患者中,报告的发病率约为0.046%.在这份报告中,我们讨论了一例接受CABG后出现Ogilvie综合征的患者。
    Coronary artery bypass graft (CABG) surgery has a major role in the management of obstructive coronary artery disease, especially in patients with diabetes or multiple vessel disease. Currently, in the USA, the annual incidence rate of CABG has been reported to be approximately 400,000. Overall, gastrointestinal (GI) complications occur in less than 2% of patients undergoing open-heart surgery. Acute colonic pseudo-obstruction, also known as Ogilvie\'s syndrome, is a disorder characterized by dilatation of the colon in the absence of an anatomic lesion that obstructs the flow of intestinal contents. This condition occurs in 0.06% of patients following cardiac surgery, and in CABG patients, the reported incidence is approximately 0.046%. In this report, we discuss a case of a patient who developed Ogilvie\'s syndrome after undergoing CABG.
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  • 文章类型: Journal Article
    这项研究的目的是比较行冠状动脉旁路移植术(CABG)的射血分数降低和保留的患者的早期和长期死亡率。这项荟萃分析遵循了2020年系统评价和荟萃分析(PRISMA)指南的首选报告项目。两名调查人员独立对PubMed进行了系统而全面的搜索,EMBASE,和Scopus从成立到2023年7月15日,使用搜索词“降低了射血分数,“\”保留射血分数,冠状动脉搭桥手术,“和”死亡率。\"布尔运算符(AND,OR)与医学主题标题(MeSH)术语一起使用以完善搜索。手动搜索所有纳入文章的参考列表,以确定潜在的相关研究。我们的搜索仅限于以英语发表的研究。该荟萃分析评估的结果包括短期死亡率(包括住院和30天死亡率)和长期死亡率。本荟萃分析共纳入5项研究。汇总的样本量为94,399名参与者。汇总分析显示,与EF保留的患者相比,EF降低的患者早期死亡的风险明显更高(风险比,RR:2.14,95%CI:1.50至3.06)。合并分析还报道,与EF保留的患者相比,EF降低的患者的晚期死亡率明显更高(RR:1.67,95%CI:1.35至2.08)。研究的汇总分析表明,EF降低的患者的早期和晚期死亡率均显着较高。强调EF评估在CABG患者危险分层中的重要性。
    The aim of this study was to compare early and long-term mortality in patients with reduced and preserved ejection fraction (EF) undergoing coronary artery bypass graft (CABG). This meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. Two investigators independently conducted a systematic and comprehensive search of PubMed, EMBASE, and Scopus from inception to July 15, 2023, using the search terms \"reduced ejection fraction,\" \"preserved ejection fraction,\" \"coronary artery bypass surgery,\" and \"mortality.\" Boolean operators (AND, OR) were used with medical subject heading (MeSH) terms to refine the search. The reference lists of all included articles were manually searched to identify potentially relevant studies. We restricted our search to studies published in the English language. The outcomes assessed in this meta-analysis included short-term mortality (including in-hospital and 30-day mortality) and long-term mortality. A total of five studies were included in this meta-analysis. The pooled sample size is 94,399 participants. Pooled analysis showed that the risk of early mortality was significantly higher in patients with reduced EF compared to patients with preserved EF (risk ratio, RR: 2.14, 95% CI: 1.50 to 3.06). The pooled analysis also reported that late mortality was significantly higher in patients with reduced EF compared to patients with preserved EF (RR: 1.67, 95% CI: 1.35 to 2.08). The pooled analysis of studies demonstrated a significantly higher rate of both early and late mortality in patients with reduced EF, emphasizing the importance of EF assessment in risk stratification for CABG patients.
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