corneoscleral graft

  • 文章类型: Case Reports
    目的:介绍一例Ahmed管植入术后6个月暴露与角膜融化和虹膜脱垂相关的复杂病例。以及需要多次同种异体移植和角膜缘重建的手术重新定位。方法:一名60岁的患者在6个月前从先前放置的Ahmed瓣膜中获得导管暴露并伴有角膜融化和虹膜脱垂的急诊室。我们的方法是使用一个角膜巩膜移植物来修复融化的角膜并避免进一步的虹膜脱垂,并使用第二个巩膜移植物来覆盖重新定位的管。结膜解剖完成后,然后用100%的酒精清洗和加深融化的角膜和管子。为试管制作了一个新的入口点,并使用酒精保存的巩膜同种异体移植物覆盖,并使用角膜巩膜同种异体移植物修复了先前的入口点,角膜外观恢复了角膜缘并避免了虹膜进一步突出。结果:6个月随访患者恢复良好,解剖修复,和IOP正常化。结论:这些病例的手术修复要求很高,并且需要手术即兴和延长手术时间。关于外科医生如何处理类似病例的文献仍然非常有限,这是关键的提示,哪些是应该避免的失误。在这种情况下,我们使用多个巩膜/角膜巩膜同种异体移植物在一个特定的方向和不同的缝合线来重建受损的角膜缘区域和恢复解剖结构。缩写:VA=视觉敏锐度,GDD=青光眼引流装置,IOP=眼压。
    Aim: To present a complex case of Ahmed tube exposure 6 months after the implantation associated with corneal melting and iris prolapse, and the surgical reposition that required multiple allografts and limbal reconstruction. Methods: A 60-year-old patient arrived at the emergency room with tube exposure combined with corneal melting and iris prolapse from a previously placed Ahmed valve 6 months prior. Our approach was to use one corneoscleral graft to repair the melted cornea and avoid further iris prolapse and a second scleral graft to cover the repositioned tube. Upon completion of conjunctival dissection, cleaning and deepithelization of the melted cornea and the tube by application of alcohol 100% followed. A new entry point was made for the tube and was covered using an alcohol-preserved scleral allograft and the previous entry point was repaired using a corneoscleral allograft with the corneal aspect restoring the limbus and avoiding further iris protrusion. Results: 6 months follow-up of the patient showed excellent recovery, anatomical restoration, and IOP normalization. Conclusion: Surgical repair of these cases can be very demanding, and requires surgical improvisation and prolonged surgical time. The literature remains very limited on how a surgeon should approach similar cases, which are the crucial tips, and which are the missteps that should be avoided. In this case, we used multiple scleral/corneoscleral allografts in a specific orientation and different sutures to reconstruct the damaged limbal area and restore the anatomy. Abbreviations: VA = Visual Acuity, GDD = Glaucoma Drainage Device, IOP = Intra Ocular Pressure.
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  • 文章类型: Journal Article
    The article reviews available data on Mooren\'s ulcer - a rare disease of, supposedly, autoimmune origin that manifests as peripheral ulceration of the cornea and poses a risk of its perforation. The variability of clinical presentation and course of the disease often leads to misdiagnosis and inadequate treatment. The present review focuses on specific signs characteristic of the disease and the most effective methods of its treatment.
    В обзоре приведены данные имеющихся клинических наблюдений о язве Мурена — редкого заболевания роговицы предположительно аутоиммунной этиологии, характеризующегося ее прогрессирующим периферическим изъязвлением и риском перфорации. Разнообразие клинических проявлений и течения заболевания нередко приводят к ошибочной постановке диагноза и последующей неверной тактике лечения. В обзоре описаны основные специфические проявления данного заболевания и наиболее эффективные методы лечения.
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  • 文章类型: Journal Article
    To assess the postoperative outcomes of limbal dermoid excision with corneoscleral graft transplantation. The charts of 8 consecutive patients (mean age: 13.0y) who had undergone limbal dermoid excision with lamellar corneoscleral graft transplantation by a single surgeon were retrospectively reviewed. Mean dermoid size was 7.75 mm (6.0-12.0 mm). Mean visual acuities (in logMAR units) before and after surgery were 1.8 and 1.7, respectively (P=0.29). Spherical equivalents were 1.3 diopter (D) before surgery and 0.7 D after surgery (P=0.40). The mean astigmatism measurements before and after surgery were 2.4 D and 1.5 D, respectively (P=0.17). Vector analysis revealed a mild change in astigmatism with a mean \"d\" of 3.2 (0.56-6.89). No intra- or post-operative complications occurred. Lamellar keratoplasty for limbal dermoids is safe and offers good cosmesis and tectonic stability. A significant decrease in the amount of astigmatism is not expected following surgery.
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  • 文章类型: Case Reports
    OBJECTIVE: To describe the technique of limbal stem cell-sparing corneoscleroplasty for the management of advanced keratoglobus.
    METHODS: A patient with bilateral advanced keratoglobus, with best-corrected visual acuity of 20/400 in the right eye and 20/200 in the left eye, underwent limbal stem cell-sparing corneoscleroplasty of the right eye. Initially, a 360-degree limbal incision with 200-μm depth was created, followed by a sublimbal tunnel dissection into the sclera, in order to conserve stem cells. Next, a limbus-to-limbus lamellar keratectomy at 200-μm depth was performed. Meanwhile, a donor corneoscleral button with preserved endothelium of the central 8 mm was fashioned. Prior to suturing the donor corneoscleral graft using a modified suturing technique to cover its scleral component, a full-thickness trephination of 8-mm diameter was completed in the central host cornea.
    RESULTS: Reepithelialization occurred within the first week. No episodes of rejection, intraocular pressure spikes, or epithelial breakdown were observed postoperatively. At the 6-month follow-up, the patient had 20/70 best-corrected vision and a smooth cornea with regular astigmatism on topography.
    CONCLUSIONS: Limbal stem cell-sparing corneoscleroplasty is a single-step technique for restoring the structural integrity of the cornea in advanced keratoglobus while preserving the host limbal stem cells.
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