■假性剥脱综合征(PES)是一种与年龄有关的全身性疾病,主要影响眼结构,其特征是晶状体上物质的沉积,睫状体,小带,角膜内皮,虹膜,和瞳孔边缘。我们比较了角膜内皮形态,眼前段参数,角膜密度测定法,以及临床单侧PES患者的临床受影响的眼睛和明显正常的眼睛之间的角膜地形图特征。
■这是一个比较,34例临床单侧PES患者的横断面研究。使用Scheimpflug成像系统检查眼前段,使用非接触镜面反射显微镜评估角膜内皮。角膜内皮细胞密度,Polymegathism,和多态性使用镜面显微镜进行评估。此外,Scheimpflug相机用于测量平坦和陡峭轴的角膜屈光力,平均角膜屈光力,最大角膜曲率测量,前房角,前房深度,前房容积,角膜体积,和顶点的角膜厚度,学生的中心,和最薄的点。在两个同心区(0-2mm和0-12mm)评价角膜密度测定法。
■总共,来自34名患者的68只眼最终被纳入研究。患者的平均(标准差)年龄为73.38(8.75)岁(范围:50-87岁)。在纳入的患者中,17(50%)为男性,17(50%)为女性。使用PES的眼睛和临床未受影响的眼睛之间的眼前节参数没有显着差异(均P>0.05)。同样,角膜内皮形态差异无统计学意义(均P>0.05)。
■我们测量的参数在临床受影响的眼睛和临床未受影响的眼睛之间没有差异。这支持PES是双边障碍的理论。考虑到与PES相关的各种并发症,在临床单侧PES患者的临床和外科治疗中,应假设双侧受累.在未来,新的研究可以增加我们对这种综合征的认识。
UNASSIGNED: Pseudoexfoliation syndrome (PES) is an age-related systemic condition that predominantly affects ocular structures and is characterized by the deposition of material on the lens, ciliary body, zonules, corneal endothelium, iris, and pupillary margin. We compared the corneal endothelial morphology, anterior segment parameters, corneal densitometry, and corneal topographic characteristics between the clinically affected and apparently normal fellow eyes of patients with clinically unilateral PES.
UNASSIGNED: This was a comparative, cross-sectional study of 34 patients with clinically unilateral PES. The anterior segment was examined using a Scheimpflug imaging system, and the corneal endothelium was assessed using a noncontact specular microscope. Corneal endothelial cell density, polymegathism, and pleomorphism were assessed using the specular microscope. Furthermore, the Scheimpflug camera was used to measure the corneal power of the flat and steep axis, mean corneal power, maximum keratometry, anterior chamber angle, anterior chamber depth, anterior chamber volume, corneal volume, and the corneal thickness at the apex point, center of the pupil, and the thinnest point. Corneal densitometry was evaluated at two concentric zones (0-2 mm and 0-12 mm).
UNASSIGNED: In total, 68 eyes from 34 patients were ultimately included in the study. The mean (standard deviation) age of the patients was 73.38 (8.75) years (range: 50-87 years). Among the included patients, 17 (50%) were male and 17 (50%) were female. The anterior segment parameters did not significantly differ between eyes with PES and their clinically unaffected fellow eyes (all P > 0.05). Similarly, no statistically significant difference was observed in corneal endothelial morphology (all P > 0.05).
UNASSIGNED: Our measured parameters do not differ between the clinically affected eye and the clinically unaffected fellow eye. This supports the theory that PES is a bilateral disorder. Considering the variety of complications associated with PES, bilateral involvement should be assumed in the clinical and surgical management of patients with clinically unilateral PES. In the future, new research could increase our understanding of this syndrome.