气味结合蛋白(OBP)是一种主要与嗅觉相关的水溶性小蛋白,促进气味分子运输到敏感淋巴中的相关受体。虽然传统上认为嗅觉是必不可少的,最近的研究表明,OBP参与调节化学通讯和防御的多种生理功能。在过去的10年里,新出现的证据表明,OBP在从不需要的外源性物质(包括植物挥发物和农药)中纯化受体周围空间中起着至关重要的作用,可能促进异源生物适应,如主机位置,适应,和农药抗性。这种多功能性可以归因于,在某种程度上,它们的结构可变性和运输有效性,隔离,并隐藏许多疏水分子。这里,我们首先概述了OBP的分类和结构特性。随后,我们讨论了昆虫OBP在通讯中的多种功能作用及其对外源性物质的适应。通过综合该领域的现有知识,我们的综述论文有助于全面了解昆虫OBP在化学生态学中的重要性,异种生物适应,为这个迷人的研究领域的未来研究铺平了道路。
Odorant binding proteins (OBPs) are small water-soluble proteins mainly associated with olfaction, facilitating the transport of odorant molecules to their relevant receptors in the sensillum lymph. While traditionally considered essential for olfaction, recent research has revealed that OBPs are engaged in a diverse range of physiological functions in modulating chemical communication and defense. Over the past 10 years, emerging evidence suggests that OBPs play vital roles in purifying the perireceptor space from unwanted xenobiotics including plant volatiles and pesticides, potentially facilitating xenobiotic adaptation, such as host location, adaptation, and pesticide resistance. This multifunctionality can be attributed, in part, to their structural variability and effectiveness in transporting, sequestering, and concealing numerous hydrophobic molecules. Here, we firstly overviewed the classification and structural properties of OBPs in diverse insect orders. Subsequently, we discussed the myriad of functional roles of insect OBPs in communication and their adaptation to xenobiotics. By synthesizing the current knowledge in this field, our review paper contributes to a comprehensive understanding of the significance of insect OBPs in chemical ecology, xenobiotic adaptation, paving the way for future research in this fascinating area of study.