chronobiological patterns

  • 文章类型: Journal Article
    (1)背景:本研究调查了天气状况之间的关系,昼夜模式,和膝关节总运动范围(ROM),以及症状的严重程度(疼痛和僵硬)在老年人膝骨关节炎。(2)方法:对28名患有膝骨关节炎的老年人进行了探索性纵向研究(平均年龄71.86±4.49岁;男性占46.4%,53.6%妇女)。我们使用视觉模拟量表(VAS)作为评估工具,用于自我报告的局部膝关节疼痛和僵硬,和ROM的测角法。测量了两次,相隔六个月,在冬天和夏天,在每个选定的日子的早晨和晚上。记录的天气因素包括温度,相对湿度,大气压力,和最大风速。(3)结果:研究显示季节和时间对疼痛和僵硬有显著影响,分别(p<0.001)。此外,季节和时间之间的显着相互作用影响了膝关节总ROM(p<0.001)。此外,时间与膝关节总ROM之间存在统计学上显著的关系(p<0.001)。(4)结论:这项研究强调了老年人膝骨关节炎的某些症状和功能方面的季节性波动和日常变化之间的复杂联系。
    (1) Background: This study investigated the relationship between weather conditions, diurnal patterns, and total knee range of motion (ROM), as well as the severity of symptoms (pain and stiffness) in older adults with knee osteoarthritis. (2) Methods: An exploratory longitudinal study was conducted on 28 older adults with knee osteoarthritis (mean age 71.86 ± 4.49 years; 46.4% men, 53.6% women). We used as assessment tools the Visual Analog Scales (VAS) for self-reported local knee pain and stiffness, and goniometry for ROM. Measurements were taken twice, six months apart, in winter and summer, in the morning and evening of each selected day. Recorded weather factors comprised temperature, relative humidity, barometric pressure, and maximum wind speed. (3) Results: The study revealed significant effects of season and time of day on pain and stiffness, respectively (p < 0.001). Additionally, a significant interaction between season and time influenced total knee ROM (p < 0.001). Moreover, there was a statistically significant relationship between time and total knee ROM (p < 0.001). (4) Conclusions: This research underscores the complex link between seasonal fluctuations and daily variations in some symptomatic and functional aspects of knee osteoarthritis in older adults.
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  • 文章类型: Journal Article
    This study explored the periodic changes in the onset of aortic dissection in a single center in northern China, with the goal to improve predictability and prevention. We collected the clinical data of 1121 patients from Hebei Province treated for acute aortic dissection at Fuwai Hospital between January 2010 and December 2016. The patterns of aortic dissection during different periods of each day, each month, and each quarter of a year were analyzed. Variations in the number of cases were summarized for weekdays, weekends, and different periods of a day in each season. We compared the differences in gender, age, body mass index, Marfan syndrome, hypertension, and the type of aortic dissection during different time periods and different seasons. In the study, 774 patients (69.1%) with type A aortic dissection and 347 patients (30.9%) with type B aortic dissection were included. The average age of 1121 patients was 51.4 ± 12.0 years. Overall, the peak period for the onset of aortic dissection in a day was between 13:00 and 18:00. There was no statistically significant difference in the number of cases between weekdays and weekend (P = 0.94). Most cases occurred in winter (30.9%); the rate of onset was the lowest in summer (16.6%). No statistically significant difference was observed between male and female patients in terms of variations during different periods of a day (P = 0.45) and seasons (P = 0.12). In conclusion, aortic dissection displayed circadian and seasonal patterns in northern China. Onset of the disease peaked between 13:00 and 18:00 in a day. Winter was the peak season for the onset of acute aortic dissection, regardless of sex, type of dissection and age.
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