目的:本研究旨在评估光学相干断层扫描(OCT)特征,以区分年龄相关性黄斑变性(AMD)中黄斑新生血管形成(MNV)的瘢痕阶段的瘢痕。
方法:20例患者的医疗记录,每组10,1型和2型MNV,被选中进行研究。选择的参与者年龄在50岁以上,并接受了全面的眼部检查以及吲哚菁绿血管造影(ICGA)。眼底荧光血管造影(FFA),和光谱光学相干层析成像(SOCT)(海德堡工程,德国),分别。定性和定量OCT测量,比如视网膜外小管的频率,存在囊样空间,疤痕区域,脉络膜厚度,视网膜厚度,视网膜层(DRIL)中存在解体,中央凹轮廓,疤痕中的视网膜层受累,对两组进行细致的评价和比较。
结果:1型MNV和2型MNV在脉络膜厚度上的显著差异在1毫米以内的鼻腔和上象限中被发现,在3毫米以内的上象限,在所有象限中,除了下象限在6毫米以内。总的来说,2型MNV显示脉络膜比1型MNV薄。
结论:尽管两组之间有几个重叠的特征,OCT能够发现有助于区分AMD中1型(息肉样脉络膜血管病变(PCV))和2型(经典)MNV的特征性特征.这种精确的区分有可能帮助眼科医生做出明智的决定,从而加强患者护理。
OBJECTIVE: This study aimed to assess the optical coherence tomography (OCT) characteristics for differentiating scars in the scarred stages of macular neovascularization (MNV) in age-related macular degeneration (AMD).
METHODS: Medical records of 20 patients, 10 in each group with type 1 and type 2 MNV, were selected for the study. Participants chosen were above 50 years of age and underwent comprehensive eye examination alongside indocyanine green angiography (ICGA), fundus fluorescence angiography (FFA), and Spectralis optical coherence tomography (SOCT) (Heidelberg Engineering, Germany), respectively. The qualitative and quantitative OCT measurements, such as the frequency of outer retinal tubulations, presence of cystoid spaces, scar area, choroid thickness, retinal thickness, presence of disorganization in retinal layers (DRIL), foveal contour, and involvement of retinal layers in the scar, were meticulously evaluated and compared between the two groups.
RESULTS: Significant disparities between type 1 MNV and type 2 MNV in choroidal thickness were identified in the nasal and superior quadrants within 1 mm, in the superior quadrant within 3 mm, and in all quadrants except the inferior quadrant within 6 mm. Overall, type 2 MNV showed thinner choroid than type 1 MNV.
CONCLUSIONS: Although there are several overlapping features noticed between the groups, the OCT was able to pick up characteristic features that aid in differentiating type 1 (polypoidal choroidal vasculopathy (PCV)) and type 2 (classic) MNV in AMD. This precise differentiation has the potential to assist ophthalmologists in making well-informed decisions, thereby enhancing patient care.