■在寻求治疗的患者样本中比较儿童期发作与迟发性注意力缺陷多动障碍(ADHD)的特征。
■在最近被诊断为多动症的101名成年患者中,使用成人多动症诊断访谈(DIVA2.0),56名受试者表现出儿童期发作的ADHD,45例显示迟发性ADHD。根据他们的社会人口统计学比较两组,临床,和神经心理特征,提供粗(OR)和调整后的赔率比(AOR),和他们的95%置信区间[95%CI]。
■与晚发性多动症相比,儿童期发病的患者的教育评分较低,(OR=0.52;95%CI[0.35,0.76]),冲动性得分更高(aOR=1.09;95%CI[1.03,1.16]),多动-冲动性ADHD症状数量增加(aOR=1.9;95%CI[1.46,2.47]),儿童创伤发生率较高(aOR=1.07;95%CI[1.01,1.13]),大麻使用障碍(aOR=1.07;95%CI[1.01,1.13]),和工作记忆障碍。没有观察到关于年龄的差异,性别,精神症状,生活质量,和自主性。
■儿童期发病的成人多动症表现出更严重的特征,相对于迟发性多动症。
To compare the characteristics of childhood-onset versus late-onset Attention Deficit Hyperactivity Disorder (ADHD) in a sample of treatment-seeking patients.
Among total of 101 adult patients who were recently diagnosed for ADHD, using the Diagnostic Interview for Adult ADHD (DIVA 2.0), 56 subjects exhibited childhood-onset ADHD, versus 45 displayed late-onset ADHD. Both groups were compared according to their sociodemographic, clinical, and neuropsychological features, providing crude (OR) and adjusted odds ratios (aOR), and their 95% confidence intervals [95% CI].
Compared to late-onset ADHD, patients with childhood-onset had a lower educational score, (OR = 0.52; 95% CI [0.35, 0.76]), a greater score of impulsivity (aOR = 1.09; 95% CI [1.03, 1.16]), an increased number of hyperactive-impulsive ADHD symptoms (aOR = 1.9; 95% CI [1.46, 2.47]), and higher rates childhood trauma (aOR = 1.07; 95% CI [1.01, 1.13]), cannabis use disorder (aOR = 1.07; 95% CI [1.01, 1.13]), and working memory impairment. No difference was observed concerning age, sex, psychiatric symptoms, quality of life, and autonomy.
Childhood-onset adult ADHD displayed a more severe profile, relative to late-onset ADHD.