catheter survival

导管存活
  • 文章类型: Journal Article
    背景:腹膜透析(PD)导管插入的理想技术应提供长期有效的导管,直到永久性肾脏替代疗法可用为止。我们在2011年开发了一种使用肾镜辅助单套管针法的技术。在这项研究中,我们报告结果,对肾镜入路与传统腹腔镜入路进行学习曲线分析和成本-效果分析。
    方法:在2005年1月至2020年12月之间,我们回顾性分析了511例采用腹腔镜或肾镜入路进行PD导管插入的患者。我们比较了患者的基线特征,手术结果,两组并发症。我们进一步分析了肾镜组,以确定成本-效果分析,在肾镜入路的学习和掌握期之间的学习曲线和并发症频率。
    结果:共有208例患者接受了腹腔镜PD导管插入,而303例患者接受了肾镜手术。肾镜组的中位导管生存期明显更长(43.1vs.60.5个月,p=0.019)。腹膜炎的发病率(29.3%vs.20.8%,p=0.035)和出口部位感染(12.5%vs.6.6%,p=0.019)在肾镜组中明显较低。成本效益分析显示,通过使用肾镜技术,医疗费用每年减少16000美元。在检查肾镜技术的学习曲线分析时,学习和掌握阶段之间的手术并发症频率没有差异。
    结论:与传统腹腔镜方法相比,肾镜技术通过减少感染并发症,有效延长导管存活时间,降低医疗费用.手术学习阶段的低并发症发生率使手术对患者和外科医生都是安全的。
    BACKGROUND: An ideal technique for peritoneal dialysis (PD) catheter insertion should provide a long-term functioning catheter until permanent renal replacement therapy becomes available. We developed a technique using the nephroscope-assisted single-trocar approach in 2011. In this study, we report the outcomes, learning curve analysis and cost-effectiveness analysisof the nephroscopic approach compared with the traditional laparoscopic approach.
    METHODS: Between January 2005 and December 2020, we retrospectively reviewed 511 patients who received PD catheter insertions using the laparoscopic or nephroscopic approach. We compared the baseline characteristics of the patients, surgical outcomes, and complications of the two groups. We further analyzed the nephroscopic group to determine the cost-effectiveness analysis, learning curve and the complication frequency between the learning and mastery periods of the nephroscopic approach.
    RESULTS: A total of 208 patients underwent laparoscopic PD catheter insertion, whereas 303 patients received nephroscopic surgery. The median catheter survival in the nephroscopic group is significantly longer (43.1 vs. 60.5 months, p = 0.019). The incidence of peritonitis (29.3% vs.20.8%, p = 0.035) and exit site infection (12.5% vs. 6.6%, p = 0.019) were significantly lower in the nephroscopic group. The cost-effectiveness analysis showed a medical expense reduction of 16000 USD annually by using the nephroscopic technique. There was no difference in the frequency of surgical complications between the learning and mastery phases when examining the learning curve analysis for the nephroscopic technique.
    CONCLUSIONS: Compared with the traditional laparoscopic approach, the nephroscopic technique effectively prolonged catheter survival and reduces health care cost by reducing infectious complications. The low complication rate during the learning phase of surgery makes the procedure safe for patients and surgeons.
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  • 文章类型: Journal Article
    目的:插管技术差异对隧道血液透析导管插入的影响尚未确定。我们旨在评估颈内静脉隧道导管置入后路的临床结果。
    方法:对2016年1月至2022年6月在一个中心进行的连续隧道导管手术进行了回顾性审核。仅包括专门放置在颈内低位后入路的导管。该研究的主要结果是12个月的导管存活,使用Kaplan-Meier存活曲线和对数秩检验进行评估。次要结果包括导管性能和手术相关并发症。
    结果:在研究期间,使用低后部技术在272例患者中插入了391个隧道颈内血液透析导管。12个月的主要通畅率为68%。96%的病例成功插入导管。4%的病例发生围手术期并发症,经常出血。导管丢失的最常见原因是功能障碍(10%)和菌血症(6%)。导管失败的最佳预测因素是高龄(HR1.02,95%CI1.00-1.04)和中心透析治疗地区(HR2.04,95%CI1.19-3.45)。
    结论:颈内静脉经管后低位入路是安全有效的。我们证实12个月的导管存活率为68%。需要进一步研究将低位后路与其他颈内静脉插管技术进行比较。
    OBJECTIVE: The impact of technical differences in cannulation technique for tunnelled haemodialysis catheter insertion is undetermined. We aimed to assess clinical outcomes of the low posterior approach for internal jugular vein tunnelled catheter placement.
    METHODS: A retrospective audit was undertaken on consecutive tunnelled catheter procedures performed at a single centre between January 2016 and June 2022. Only catheters specifically placed with a low posterior internal jugular approach were included. The study\'s primary outcome was 12-month catheter survival, evaluated using the Kaplan-Meier survival curve and log-rank test. Secondary outcomes included catheter performance and procedure-related complications.
    RESULTS: During the study period, 391 tunnelled internal jugular haemodialysis catheters were inserted in 272 patients using the low posterior technique. The 12-month primary patency rate was 68%. Catheter insertion was successful in 96% of cases. Peri-procedural complications occurred in 4% of cases, most frequently bleeding. The most common reasons for catheter loss were dysfunction (10%) and bacteraemia (6%). The best predictors of catheter failure were advanced age (HR 1.02, 95% CI 1.00-1.04) and in-centre dialysis treatment locality (HR 2.04, 95% CI 1.19-3.45).
    CONCLUSIONS: The low posterior approach for internal jugular vein tunnelled catheter insertion is effective and safe. We demonstrated a 12-month catheter survival rate of 68%. Further research comparing the low posterior approach with other internal jugular vein cannulation techniques is warranted.
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  • 文章类型: Multicenter Study
    背景:PD导管尖端迁移是常见的并发症,也是导管故障的重要原因。从这个角度来看,我们介绍了我们在新导管和新技术方面的经验,该技术涉及使用新的三袖带PD导管和低进入部位,以试图防止PD导管迁移.
    方法:在5年的时间里,在一个以上的PD中心对503例PD患者进行了研究。
    结果:在5年随访期间,我们记录的导管迁移百分比为零。其他技术并发症为引流不良,占3.4%,网膜包裹占2.8%,早期渗漏3.4%,导管置换占2.4%。在研究结束时,PD导管1年生存率为97.6%.
    结论:我们的新型三套囊PD导管和我们的低进入方法似乎在预防PD导管迁移和减少其他机械并发症方面有效。
    BACKGROUND: PD catheter tip migration is a common complication and a significant cause of catheter malfunction. In this perspective, we present our experience with a new catheter and a new technique that involves the use of a new triple cuff PD catheter and a low entry site in an attempt to prevent PD catheter migration.
    METHODS: A total of 503 incident PD patients have been studied in more than one PD center over a period of 5 years.
    RESULTS: During the 5-year follow up we recorded zero percent catheter migration. Other technical complications were poor drainage in 3.4%, omental wrap in 2.8%, early leakage in 3.4%, and catheter replacement in 2.4%. By the end of the study, the one-year PD catheter survival was 97.6%.
    CONCLUSIONS: Our new triple cuff PD catheter and our low-entry approach seem to be effective in preventing PD catheter migration and minimizing other mechanical complications.
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  • 文章类型: Journal Article
    随着慢性肾病患者数量的增加,肾脏科医师的活动逐渐扩大。这项研究评估了肾脏病学家进行的外周中心静脉导管(PICC)的安全性和成功率。
    我们回顾性分析了一个医疗中心的医疗记录。所有患者均接受了两名肾脏科医师的PICC手术。拔除导管的原因分为意外拔除;治疗终止;导管闭塞;血管血栓形成;导管相关性感染,或病人死亡。总体导管并发症定义为导管闭塞,血管血栓形成,或导管相关感染。
    在286例患者中,共进行了335次导管插入。总的来说,335例中的251例患者在随访期间需要拔除导管.在251例有导管相关并发症的病例中,有48例(19.1%)拔除了导管。在单变量和多变量分析中,糖尿病与导管相关性感染相关.导管1个月生存率为85.3%。在单变量和多变量分析中,糖尿病和透视引导下的导管插入与良好的导管存活率相关.
    我们的研究结果表明,肾脏科医师插入PICC的成功率和并发症发生率较低。这些发现表明,已经精通其他程序的介入肾脏病学家可以扩大其活动和利润领域。
    UNASSIGNED: As the number of patients with chronic kidney disease increases, nephrologist activities are gradually expanding. This study evaluated the safety and success of peripherally inserted central catheter (PICC) performed by nephrologists.
    UNASSIGNED: We retrospectively analyzed the medical records of a medical center. All patients underwent a PICC procedure by two nephrologists. The reasons for catheter removal were classified as accidental removal; treatment termination; catheter occlusion; vessel thrombosis; catheter-related infection, or patient death. Overall catheter complications were defined as catheter occlusion, vessel thrombosis, or catheter-related infection.
    UNASSIGNED: A total of 335 catheterizations among 286 patients were performed. Overall, catheter removal was required during follow-up in 251 of 335 cases. The catheter was removed in 48 out of 251 (19.1%) cases with catheter-related complications. In univariate and multivariate analyses, diabetes mellitus was associated with catheter-related infection. The catheter survival rates were 85.3% at 1 month. In univariate and multivariate analyses, diabetes mellitus and fluoroscopy-guided insertion were associated with favorable catheter survival.
    UNASSIGNED: The results of our study showed high success and low complication rates for PICC insertion by nephrologists. These findings indicate that interventional nephrologists already skilled in other procedures can expand their field of activity and profit.
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  • 文章类型: Journal Article
    OBJECTIVE: There is an ongoing debate about the ideal technique for peritoneal dialysis (PD) catheter insertion in patients with end-stage renal disease (ESRD). A half-percutaneous (\"Half-Perc\") technique shares some of the advantages of both percutaneous technique and traditional open surgery. This retrospective study aimed to evaluate the clinical feasibility, safety, and effects of the \"Half-Perc\" technique for PD catheter placement, and to compare the clinical outcomes of the \"Half-Perc\" technique with various imaging-assisted percutaneous techniques from the current literature.
    METHODS: We included 280 consecutive patients with ESRD who underwent the \"Half-Perc\" insertion of the first PD catheter between September 2016 and September 2019. We recorded baseline characteristics, operative parameters, catheter-related complications, catheter survival, and the reason behind PD cessation.
    RESULTS: We included 174 men and 106 women, with a mean age of 50.4 years (range, 11-85 years). The mean operative time was 28.8 min (range, 15-38 min) and technical success rate was observed in 278 patients (99.3%). There were 28 episodes (10%) of mechanical complications with initial catheters occurring during the follow-up. Catheter malfunctions were the most common mechanical complication and were observed in 15 patients. Peritonitis was the most frequent catheter-related complication, with 32 episodes of peritonitis observed in 29 (10.4%) patients. After a mean follow-up period of 15.4 months (range, 2-36 months), 235 patients (83.9%) survived with their initial PD catheter by the end of the study. Of the 280 patients analyzed, 35 patients (12.5%) ceased PD at some stage during follow-up. The most common reason for PD cessation was kidney transplantation (18 patients (6.4%)), followed by death (9 patients (3.2%)) and switch to hemodialysis (HD) (7 patients (2.5%)), and recovery of renal failure (1 patient (0.4%)).
    CONCLUSIONS: The \"Half-Perc\" technique, including a modified metal trocar, is a simple, safe, and effective method for PD catheter placement that can be used for patients with ESRD.
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  • 文章类型: Journal Article
    在超重和肥胖患者中放置用于慢性肾病(CKD)的腹膜透析导管(PDC)是困难的,因为手术领域更深。该患者子集的生存率和并发症文献不一致,我们试图在印度人口中分析这个研究问题。
    我们回顾性分析了在印度两家三级政府医院的“超重和肥胖”队列(“O”)中,由肾脏科医生使用外科手术开腹手术插入的PDC的生存和并发症,并将结果与正常体重队列(\'N\')进行比较,随访12-36个月。
    245个PDC通过外科手术剖腹手术插入,\'N\'与\'O\'的比例为169:76。'O'组更多的是农村居民(P=0.003)和腹部手术后(P=0.008)的患者。1年、2年和3年死亡审查导管存活率为98.6%,95.8%,\'O\'组中分别为88.2%,97.6%,N组分别为94.5%和91.8%(P=0.52)。患者生存率(P=0.63),机械性并发症(P=0.09)和感染性并发症(P=0.93)在手术组中具有可比性,尽管手术具有技术挑战性.难治性腹膜炎相关的PDC去除具有可比性(P=0.54)。先前的血液透析或导管相关的血流感染或糖尿病对结果没有贡献。
    肥胖和超重CAPD患者的导管存活率和患者存活率不劣于正常体重患者。机械,和感染性并发症是相当的,尽管技术上具有挑战性的腹部地形\'O\'组。在肥胖和超重中,CAPD的整体表现良好。
    UNASSIGNED: Peritoneal dialysis catheter (PDC) placement for chronic kidney disease (CKD) amongst overweight and obese patients is difficult owing to deeper operating field. Literature being discordant on survival and complications in this patient subset, we attempted to analyse this research question in Indian population.
    UNASSIGNED: We retrospectively analysed PDC inserted by nephrologist using surgical minilaparotomy for survivals and complications amongst \'overweight and obese\' cohort (\'O\') at two tertiary care government hospitals in India, and compared results with normo-weight cohort (\'N\'), with 12-36 months follow-up.
    UNASSIGNED: 245 PDCs were inserted by surgical minilaparotomy and \'N\' to \'O\' ratio was 169:76. \'O\' group were more rural residing (P = 0.003) and post-abdominal surgery (P = 0.008) patients. The 1, 2, and 3-year death censored catheter survival rate was 98.6%, 95.8%, and 88.2% respectively in \'O\' group, and 97.6%, 94.5% and 91.8% in \'N\' group respectively (P = 0.52). Patient survival (P = 0.63), mechanical complications (P = 0.09) and infective complications (P = 0.93) were comparable despite technically challenging surgery in \'O\' group. Refractory peritonitis related PDC removal was comparable (P = 0.54). Prior haemodialysis or catheter related blood stream infections or diabetes were non-contributory to results.
    UNASSIGNED: Catheter survival and patient survival amongst obese and overweight CAPD patients was non-inferior to normal weight patients. Mechanical, and infective complications were comparable despite technically challenging abdominal terrain in \'O\' group. The overall CAPD performance was good amongst obese and overweight.
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  • 文章类型: Journal Article
    The aim of the present study was to perform a comparative analysis of peritoneal dialysis catheter (PDC) insertion between blind and surgical methods by nephrologists.
    The present study enrolled 249 peritoneal dialysis patients who received first-time PDC insertion. All PDC insertions were performed using either the blind or surgical method. In our hospital during the study period, two of three nephrologists performed the blind method routinely in all eligible patients (blind group), and one of three nephrologists performed the surgical method in all eligible patients (surgical group). Catheter outcomes, including infectious or mechanical complications, functional parameters, and catheter survival, were evaluated.
    The numbers of patients underwent surgical or blind methods were 105 and 144, respectively. The use of systemic analgesics in the surgical group was higher than that in the blind group. The operation time was longer in the blind group than in the surgical group. The D0 level and peritoneal Kt/V were similar between the two groups. There was no significant difference in infectious and mechanical complications between the two groups. The catheter survival and intervention-free survival were similar between the two groups (P = .995 for catheter survival and P = .723 for intervention-free survival).
    Our study shows that catheter outcomes are similar between blind and surgical insertion techniques performed by nephrologists. These findings reveal that patients without previous major abdominal surgery would be suitable to receive any one of the two methods according to the operator-friendly technique.
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  • 文章类型: Journal Article
    To evaluate the efficacy and safety of ultrasound-guided percutaneous peritoneal dialysis catheter insertion using multifunctional bladder paracentesis trocar.
    A retrospective review of 103 ESRD patients receiving percutaneous PD catheter insertion using a multifunctional bladder paracentesis trocar under ultrasound guidance at a single center between May 2016 and May 2018. Mechanical complications and catheter survival were evaluated over a 12-month follow-up.
    Catheterization using this technique required only 10-30 minutes from the beginning of local anesthesia to the end of skin suture at the puncture site (mean 18 ± 7 minutes) and an incision length of 2-4 cm. Moreover, only four of 103 cases required catheter removal due to poor drainage within one month after surgery, with a success rate of 96.19%. Among failures, omentum wrapping was cause in two cases, catheter displacement in one case, and protein clot blockage in one case, while there were no instances of organ injury, severe hemorrhage, peritubular leakage, hernia, peritonitis, or exit infection within one month of PD catheter insertion. Catheter survival at 1 year was 92.2%.
    Percutaneous PD catheter insertion using a multifunctional bladder paracentesis trocar and ultrasound guidance is a feasible technique for ESRD patients.
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  • 文章类型: Journal Article
    Midline catheters (MCs) are commonly inserted in patients with difficult venous access (DVA) needing peripheral access. Recently, the alternative placement of ultrasound-guided long peripheral catheters (LPCs) has spread. However, no study has compared the reliability of the 2 devices. This study aims to compare the safety and reliability of MCs and LPCs in DVA patients.
    A retrospective cohort study was conducted, enrolling 184 DVA patients. Polyurethane MCs and 2 lengths of polyethylene LPCs (8/10 cm and 18 cm) were compared. The independent effect of catheter type on uncomplicated catheter survival was determined through a Cox regression analysis.
    The relative incidences of overall catheter-related complications (CRCs) were 15.84 of 1,000, 10.64 of 1,000, and 6.27 of 1,000 catheter-days for 8/10 cm-LPCs, 18 cm-LPCs, and MCs, respectively. The relative incidences of catheter-related bloodstream infections were 0.72 of 1,000 for both length LPCs and 0.48 of 1,000 catheter-days for MCs. Compared to MCs, a significant increase in CRC risk for 8/10 cm LPCs (hazard ratio [HR] 5.328; 95% confidence interval [CI] 2.118-13.404; P < 0.001) was found, along with a nonsignificant trend toward an increased risk for 18 cm-LCPs (HR 2.489; 95% CI 0.961-6.448; P = 0.060).
    MCs allow for longer uncomplicated indwelling times than LPCs. The decision regarding which catheter to use should consider the planned duration of intravenous therapy, the patient\'s clinical condition, and the cost of the device.
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  • 文章类型: Journal Article
    International guidelines recommended a delayed start of peritoneal dialysis at least 2 weeks between catheter insertion and continuous peritoneal dialysis therapy initiation (break-in period). Up to now, the optimal duration of the break-in period is still unclear. The aim of our study was to evaluate in patients, with immediate initiation of continuous peritoneal dialysis, the efficacy of a double purse-string around the inner cuff in preventing mechanical and infectious complications either in semi-surgical or surgical catheter implantation. From January 2011 to December 2018, 135 peritoneal dialysis catheter insertions in 125 patients (90 men and 35 women, mean age 62.02 ± 16.7) were performed. Seventy-seven straight double-cuffed Tenckhoff catheters were implanted semi-surgically on midline under the umbilicus by a trocar, and 58 were surgically implanted through the rectus muscle. In all patients, continuous peritoneal dialysis was started immediately after catheter placement. Mechanical and infectious catheter-related complications during the first 3 months after initiation of continuous peritoneal dialysis were recorded. The overall incidence of leakages, catheter dislocations, peritonitis, and exit-site infections was 4/135 (2.96%), 2/135 (1.48%), 14/135 (10.3%), and 4/135 (2.96%), respectively. Regarding the incidence of catheter-related complications, no bleeding events, bowel perforations, or hernia formations were observed with either the semi-surgical or surgical technique. Double purse-string technique around the inner cuff allows an immediate start of continuous peritoneal dialysis both with semi-surgical and surgical catheter implantation. This technique is a safe and feasible approach in patients needing an urgent peritoneal dialysis.
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