■体育活动(PA)被广泛推荐用于预防和对抗肥胖,但治疗肥胖最有效的PA模式仍不清楚.心脏代谢指数(CMI),从腰围高度比率和甘油三酯与高密度脂蛋白-胆固醇比率得出,是评估肥胖的新指标。然而,不同PA模式与CMI之间的关系仍未阐明。
■本研究旨在探讨美国成年人不同PA模式与CMI之间的关联。
■在CMI中具有完整信息的参与者,PA模式,和国家健康和营养检查调查数据库(2007-2016)中的其他协变量被纳入本研究.利用多元线性回归模型探讨PA模式与CMI之间的关系。此外,分层分析,相互作用检验和约束三次样条(RCS)回归分析用于研究关联的稳定性和非线性,分别。
■本研究共纳入16,442名成年人。在调整所有潜在协变量后,只有规律活动组与CMI降低显著相关(β=-0.13,95%CI:0.19至-0.07,P<0.0001),而周末勇士组没有达到同等的CMI降低(β=-0.09,95%CI:0.32~0.14,P=0.4204)。亚组分析和交互作用测试显示,CMI-PA关联在年龄≤45岁或>60岁、受教育程度较高的亚组更为明显。以及现在的饮酒者。此外,RCS分析表明,一周内总PA显著,与非不活动成年人的CMI非线性相关,并且总共330分钟以上的PA可以获得有利的CMI降低。
■经常活动与CMI显着降低有关,虽然是周末战士和不够活跃,但并不能获得同等的好处。对于非不活跃的个体,每周从事PA超过330分钟有助于有效降低CMI。
UNASSIGNED: Physical activity (PA) is widely recommended for preventing and combating obesity, but the most effective PA pattern for treating obesity remains unclear. Cardiometabolic index (CMI), derived from waist height ratio and triglycerides to high-density lipoprotein-cholesterol ratio, is a novel indicator for evaluating obesity. However, the relationship between different PA patterns and CMI remains unelucidated.
UNASSIGNED: This study aimed to explore the association between different PA patterns and CMI in U.S. adults.
UNASSIGNED: Participants with complete information in CMI, PA patterns, and other covariates in the National Health and Nutrition Examination Survey database (2007-2016) were included in this study. Multivariate linear regression models were utilized to explore the relationship between PA patterns and CMI. Moreover, stratified analyses, interaction tests and restricted cubic spline (RCS) regression analysis were used to investigate the stability and nonlinearity of the association, respectively.
UNASSIGNED: A total of 16,442 adults were included in this study. After adjusting for all potential covariates, only the regularly active group was significantly associated with CMI reduction (β = -0.13, 95% CI: 0.19 to -0.07, P < 0.0001), while the weekend warriors group did not achieve equivalent CMI reduction (β = -0.09, 95% CI: 0.32 to 0.14, P = 0.4204). Subgroup analyses and interaction tests revealed that the CMI-PA association was more pronounced in the subgroup with age≤45 or >60, with higher education level, and who are current drinkers. Furthermore, RCS analysis indicated that total PA in a week was significantly, nonlinearly associated with CMI in non-inactive adults, and that a total of PA more than 330 min can reap favorable CMI reduction.
UNASSIGNED: Being regularly active is associated with significant CMI reduction, while being weekend warriors and insufficiently active do not achieve equivalent benefits. For non-inactive individuals, engaging in PA for more than 330 min weekly helps to reduce CMI effectively.