■评估在玻璃离聚物水泥中掺入新型添加剂以改善生物相容性和机械性能的功效。
■尽管玻璃离聚物水泥(GIC)具有多种优势,它对于医疗应用来说不够坚固,它的生物相容性值得怀疑。为了提高生物相容性及其机械性能,进行了一项研究,以调查添加石墨烯的潜在好处,碳纳米管,羟基磷灰石,和生物活性玻璃到GIC。目的是提高GIC的机械性能和生物相容性。
■通过创建五个组来制备改性玻璃离聚物水泥。羟基磷灰石,多壁碳纳米管,石墨烯,石墨烯和生物活性玻璃以10:1的重量比掺入,分别。第5组被指定为对照组并使用富士II型GIC。制备90个样品后,将它们在去离子水中放置一天,然后评估它们的抗压强度,显微硬度,和径向抗拉强度,并通过与L929哺乳动物成纤维细胞直接接触检查其体外细胞毒性。
■使用平均值和标准偏差描述性统计来检查数据。通过TukeyHSD检验和使用S.P.S.S.的单向ANOVA进行比较评估。软件。
■它表明第3组的抗压强度(144.478-3.989),径向抗拉强度(20.29+-0.8601),和显微硬度(131+-3.536)与其他组相比,而在生物相容性(活力%)组1[82.55],第3组[76.49],第4组[87.63],而第2组[58.02]。
■第3组在显微硬度方面具有更好的物理性能,径向抗拉强度,和抗压强度,比其他组。在生物相容性方面,组1、组3、组4和组5是非细胞毒性的,同时多壁碳纳米管组(组2)具有细胞毒性潜力。
UNASSIGNED: To evaluate the efficacy of incorporated novel additives in Glass Ionomer Cement to ameliorate biocompatibility and mechanical properties.
UNASSIGNED: Though Glass Ionomer Cement (GIC) has multiple advantages, it is not strong enough for medical applications, and its biocompatibility is questionable. To improve biocompatibility and its mechanical properties, a study was performed to investigate the potential benefits of adding graphene, carbon nanotubes, hydroxyapatite, and bioactive glass to GIC. The objective was to enhance both the mechanical properties and biocompatibility of GIC.
UNASSIGNED: Modified Glass Ionomer Cement was prepared by creating five groups. Hydroxyapatite, multi-walled carbon nanotubes, graphene, and bioactive glass were incorporated in a 10:1 weight ratio, respectively. Group 5 was designated as the control group and used Fuji Type II GIC. After preparing 90 samples, they were kept in deionized water for a day and then evaluated their compressive strength, microhardness, and diametral tensile strength, and also checked their in vitro cytotoxicity by direct contact with L929 mammalian fibroblast cells.
UNASSIGNED: The data were examined using mean and standard deviation descriptive statistics. The comparative evaluation was done via Tukey HSD test and one-way ANOVA using S.P.S.S. software.
UNASSIGNED: It showed that Group 3 had better results in compressive strength (144.478+- 3.989), diametral tensile strength (20.29+- 0.8601), and microhardness (131+-3.536) when compared with other groups while in the biocompatibility (viability %) Group 1 [82.55], Group 3 [76.49], Group 4 [87.63], while Group 2[58.02].
UNASSIGNED: Group 3 has better physical properties in microhardness, diametral tensile strength, and compressive strength, than the other groups. In Biocompatibility, Group 1, Group 3, Group 4, and Group 5 were noncytotoxic at the same time multi-walled carbon nanotubes group (Group 2) had cytotoxic potential.