浆细胞瘤是单一的,异常浆细胞的孤立肿瘤。它可以在骨头内发育,称为骨孤立性浆细胞瘤,或者骨头外,称为骨外(髓外)浆细胞瘤,不会扩散到身体的其他部位。浆细胞瘤,后纵隔的罕见表现,通常出现在骨或软组织中的单发或多发病变。标准治疗包括确定性放疗,可能治愈髓外病例。预后各不相同,在不并发多发性骨髓瘤和高风险细胞遗传学恶化的情况下更有利。该病例涉及一名80年代初的男性,有广泛的病史,表现为吞咽困难和呼吸困难。诊断显示与多发性骨髓瘤相关的罕见后纵隔浆细胞瘤,强调及时诊断和治疗的重要性。
A plasmacytoma is a single, isolated tumour of abnormal plasma cells. It can develop within the bone, known as solitary plasmacytoma of bone, or outside the bone, referred to as extraosseous (extramedullary) plasmacytoma, without spreading to other parts of the body. Plasmacytoma, an uncommon presentation in the posterior mediastinum, usually arises as solitary or multiple lesions in bone or soft tissues. The standard treatment involves definitive radiotherapy, potentially curative for extramedullary cases. The prognosis varies, being more favourable without concurrent multiple myeloma and worsening with high-risk cytogenetics. The case involves a male in his early 80s with an extensive medical history presenting with difficulty swallowing and dyspnoea. The diagnosis revealed a rare posterior mediastinal plasmacytoma associated with multiple myeloma, emphasising the importance of prompt diagnosis and treatment.