bilateral

双边
  • 文章类型: Case Reports
    疱疹性上皮性角膜炎是由单纯疱疹病毒(HSV)引起的角膜病毒感染。它通常表现为单侧疾病。双侧受累是疱疹性上皮性角膜炎的罕见表现,只占病例的一小部分。通过分享这个案例,我们的目标是有助于了解双侧疱疹性上皮性角膜炎,并促进该领域的进一步研究,以优化患者护理和结果一个13岁的儿童,一个已知的过敏病例,因疼痛而被送到眼科诊所,畏光,右眼发红(OD)三天。患者被诊断为双侧疱疹性上皮性角膜炎;他开始每天四次莫西沙星滴眼液,Artelac(透明质酸钠)每两小时,卡波姆HS,更昔洛韦软膏每天五次。双侧疱疹性上皮性角膜炎是HSV感染的罕见表现,与单侧疾病相比,其管理带来了独特的挑战。双侧疱疹性上皮性角膜炎的诊断主要基于临床表现。包括角膜上的双侧树突状或地理溃疡。荧光素染色是观察角膜溃疡的有价值的工具。在我们的案例中,尽管关于双侧疱疹性上皮性角膜炎的文献有限,但在没有明显前房炎症的情况下,双侧树突状溃疡的存在支持了双侧疱疹性上皮性角膜炎的诊断,管理原则与单侧疾病的原则保持一致.早期识别,迅速开始抗病毒治疗,密切的后续行动对于成功的结果至关重要。
    Herpetic epithelial keratitis is a viral infection of the cornea caused by the herpes simplex virus (HSV). It typically presents as a unilateral disease. Bilateral involvement is a rare manifestation of herpetic epithelial keratitis, accounting for only a small percentage of cases. By sharing this case, we aim to contribute to the understanding of bilateral herpetic epithelial keratitis and stimulate further research in this area to optimize patient care and outcomes A 13-year-old child, a known case of atopy, presented to the ophthalmology clinic with a complaint of pain, photophobia, and redness in the right eye (OD) for three days. The patient was diagnosed as a case of bilateral herpetic epithelial keratitis; he was started on moxifloxacin eye drops four times a day, Artelac (sodium hyaluronate) every two hours, carbomer HS, ganciclovir ointment five times per day. Bilateral herpetic epithelial keratitis is a rare manifestation of HSV infection, and its management poses unique challenges compared to unilateral disease. The diagnosis of bilateral herpetic epithelial keratitis is primarily based on clinical findings, including bilateral dendritic or geographic ulcers on the cornea. Fluorescein staining is a valuable tool for visualizing corneal ulcers. In our case, the presence of bilateral dendritic ulcers in the absence of significant anterior chamber inflammation supported the diagnosis of bilateral herpetic epithelial keratitis Despite the limited literature on bilateral herpetic epithelial keratitis, the principles of management remain consistent with those of unilateral disease. Early recognition, prompt initiation of antiviral therapy, and close follow-up are crucial for successful outcomes.
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  • 文章类型: Case Reports
    先兆子痫,一种复杂的多系统疾病,主要影响肾脏和肝脏,通过孕妇的高血压和器官功能障碍表现出来。先兆子痫也可引起眼部体征,但它们并不常见。渗出性视网膜脱离(ERD)是一种不寻常但危险的后果。本研究提供了在经历先兆子痫时经历渗出性视网膜脱离的患者的全面临床描述和治疗。一名28岁的沙特女性,没有病史或手术史,由于严重先兆子痫和引产失败,接受了紧急剖宫产(CS)。病人抱怨无痛的视力模糊,从分娩白天开始,中央黑斑和视力下降。该患者被送往医院进行血压监测和进一步调查。患者开始静脉注射肼屈嗪(IV)和拉贝洛尔PO以控制BP。该患者因引产失败后出现重度子痫前期,经剖宫产分娩,产后四周她的视力得到了改善。作为先兆子痫的结果的视网膜脱离是保守的管理,预后普遍良好。以前的研究一直强调多学科方法的重要性,促进产科医生和眼科医生之间的合作。这种协作策略不仅确保全面的护理,而且有助于早期发现,及时干预,并改善了妊娠期间影响孕产妇健康和眼科健康的疾病的管理结果。
    Preeclampsia, a complex multisystem disorder predominantly impacting the kidneys and liver, manifests through hypertension and organ dysfunction in expectant mothers. Preeclampsia can also cause ocular signs, but they are uncommon. Exudative retinal detachment (ERD) is one such unusual but dangerous consequence. A thorough clinical description and therapy of a patient who experienced exudative retinal detachment while experiencing preeclampsia are provided in this study. A 28-year-old Saudi female, with no medical or surgical history, underwent an emergency cesarean section (CS) due to severe preeclampsia and failed induction of labor. The patient complained of painless blurry vision, with central dark spot and decreased vision starting from labor daytime. The patient was admitted to the hospital for blood pressure monitoring and further investigations. The patient was started on hydralazine intravenous (IV) and labetalol PO to control BP. The patient was delivered by cesarean section for preeclampsia with severe features after the failure of labor induction, and she had improved her vision by four weeks postpartum. Retinal detachment as a consequence of preeclampsia is conservatively managed, with a generally favorable prognosis. Previous studies have consistently emphasized the critical importance of a multidisciplinary approach that fosters collaboration between obstetricians and ophthalmologists. This collaborative strategy not only ensures comprehensive care but also facilitates early detection, timely intervention, and improved management outcomes for conditions affecting both maternal health and ophthalmic well-being during pregnancy.
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  • 文章类型: Case Reports
    在像印度这样的国家,结核病是地方性的,可以影响任何器官,尽管肺结核是猖獗的,肺外是罕见的。影响腮腺的结核病是罕见的,通常是单方面的。然而,引起双侧腮腺冷脓肿的结核分枝杆菌更为罕见。这里,我们介绍了一例年轻女性,表现为腮腺区域双侧缓慢增长的肿胀,夜间体温升高两个月。在临床检查中,没有看到炎症的迹象。超声检查显示厚壁低回声集合,其中隔和内部回声累及腮腺的浅叶和深叶。细针穿刺细胞学(FNAC)提示在ZN染色上检测到干酪样肉芽肿和抗酸杆菌,从而确认冷脓肿的诊断。她服用了抗结核药物,肿胀的大小急剧减少。
    Tuberculosis being endemic in country like India can affect any organ though pulmonary tuberculosis is rampant and extrapulmonary is rare. Tuberculosis affecting parotid gland is a rare occurrence, usually unilateral. However, Mycobacterium tuberculosis causing cold abscess in bilateral parotid glands is even rarer. Here, we present a case of a young female presented with bilateral slow-growing swelling in the parotid region with evening raise of temperature for two months. On clinical examination, no signs of inflammation were seen. Ultrasonography showed thick-walled hypoechoic collection with septae and internal echoes within involving both superficial and deep lobes of the parotid gland. Fine-needle aspiration cytology (FNAC) suggested a caseating granuloma and acid fast bacilli were detected on ZN staining, thereby confirming the diagnosis of cold abscess. She was put on antitubercular drugs and there was a drastic reduction in the size of swelling.
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  • 文章类型: Journal Article
    喉头膨出,充满空气的喉室阑尾的异常扩张,是一种罕见的情况,主要是单方面出现。然而,双边事件极为罕见。在这篇文章中,我们介绍了一例双侧喉膨出的病例,并进行了全面的文献综述。一名57岁男性出现呼吸困难,stridor,和双侧颈部肿块。他的病史包括慢性咳嗽和间歇性声音嘶哑。在三个月的时间里,颈部肿块逐渐扩大,导致呼吸窘迫.有趣的是,他否认经历过减肥,食欲下降,或发烧。临床检查显示相当大,颈部两侧柔软的肿块,阻塞淋巴结评估。计算机断层扫描(CT)成像证实存在左合并喉囊肿和右合并喉囊肿。随后,患者接受了气管造口术。良性活检结果排除恶性肿瘤。双侧喉癌的手术切除导致了顺利的恢复。“喉癌”一词由Virchow于1867年引入,用于描述与Morgagni心室相关的囊的异常扩张。诊断涉及全面的病史,体检,和放射成像,尤其是CT,将喉癌与其他疾病区分开来。通常无症状,它们通常在50岁左右偶然发现,尽管声音变化或呼吸困难等症状可能会出现。对文献的审查确定了77起记录在案的案件,主要是男性,表现出各种症状和治疗方式。该病例强调了双侧合并喉膨出的罕见性,强调及时诊断和手术干预以获得良好结果的重要性。综合研究揭示了不同的临床方面,强调继续调查以加强管理策略的必要性。
    Laryngocele, an abnormal dilation of the appendix of the laryngeal ventricle filled with air, is a rare condition predominantly presenting unilaterally. However, bilateral occurrences are exceedingly rare. In this article, we present a case of bilateral laryngocele along with a comprehensive literature review. A 57-year-old male presented with dyspnea, stridor, and bilateral neck masses. His medical history included chronic cough and intermittent hoarseness. Over a 3 month period, the neck masses progressively enlarged, resulting in respiratory distress. Interestingly, he denied experiencing weight loss, decreased appetite, or fever. Clinical examination revealed sizable, soft masses on both sides of the neck, obstructing lymph node assessment. Computed tomography (CT) imaging confirmed the presence of a left combined laryngopyocele and a right combined laryngocele. Subsequently, the patient underwent tracheostomy. Benign biopsy results excluded malignancy. Surgical excision of bilateral laryngoceles resulted in an uneventful recovery. The term \"laryngocele\" was introduced by Virchow in 1867 to describe the abnormal dilation of the saccule associated with Morgagni\'s ventricle. Diagnosis involves a thorough patient history, physical examination, and radiological imaging, notably CT, to differentiate laryngoceles from other conditions. Typically asymptomatic, they are often incidentally discovered around age 50, although symptoms such as voice changes or breathing difficulties can manifest. A review of the literature identified 77 documented cases, primarily in males, exhibiting various symptoms and treatment modalities. This case underscores the rarity of bilateral combined laryngocele, emphasizing the importance of timely diagnosis and surgical intervention for favorable outcomes. Comprehensive research reveals diverse clinical aspects, highlighting the necessity for continued investigation to enhance management strategies.
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  • 文章类型: Journal Article
    背景:一些研究比较了同期双侧和分期双侧髋和膝关节置换的利弊,但这两种手术选择的结果仍然存在争议。本研究旨在评估人口统计特征,意大利双侧一期全髋关节和膝关节置换术的发生率和住院率。
    方法:使用意大利卫生部的国家医院出院报告(SDO)收集数据。这项研究涉及2001年至2015年进行髋关节置换术和2001年至2016年进行膝关节置换术的成年人(20岁以上)。
    结果:总体而言,进行了1,544例双侧同期髋关节置换术。发病率为每100,000名成年意大利居民0.21例。男女比例为1.1。平均住院天数为11.7±11.8天。主要的编码诊断是:骨关节炎,局部化,小学,骨盆区和大腿(ICD代码:715.15)。进行了2,851例双侧同时膝关节置换。发病率为每100,000名成年意大利居民0.37例。男女比例为0.6。平均住院天数为7.7±5.8天。主要的编码诊断是:骨关节炎,局部化,小学,小腿(ICD代码:715.16)。
    结论:在意大利,作为双侧关节置换的主要原因,髋和膝骨关节炎的负担是显著的。国家登记纵向分析可以为建立国际指南提供数据,该指南涉及一个阶段双侧同时进行髋关节或膝关节置换与两个阶段的适当适应症。
    BACKGROUND: Several studies have compared the pros and cons of simultaneous bilateral versus staged bilateral hip and knee replacement but the outcomes of these two surgical options remains a matter of controversy. This study aimed to evaluate demographic features, incidence and hospitalization rates of bilateral one stage total hip and knee arthroplasty in Italy.
    METHODS: The Italian Ministry of Health\'s National Hospital Discharge Reports (SDO) were used to gather data. This study referred to the adult population (+ 20 years of age) from 2001 to 2015 for hip arthroplasty and from 2001 to 2016 for knee arthroplasty.
    RESULTS: Overall, 1,544 bilateral simultaneous hip replacement were carried out. The incidence rate was 0.21 cases per 100,000 adult Italian residents. Male/female ratio was 1.1. The average days of hospital stay was 11.7 ± 11.8 days. The main primary codified diagnosis was: osteoarthrosis, localized, primary, pelvic region and thigh (ICD code: 715.15). 2,851 bilateral simultaneous knee replacement were carried out. The incidence rate was 0.37 cases per 100,000 adult Italian residents. Male/female ratio was 0.6. The average days of hospital stay was 7.7 ± 5.8 days. The main primary codified diagnosis was: osteoarthrosis, localized, primary, lower leg (ICD code: 715.16).
    CONCLUSIONS: The burden of hip and knee osteoarthrosis as a leading cause of bilateral joint replacement is significant in Italy. The national registers\' longitudinal analysis may provide data for establishing international guidelines regarding the appropriate indications for one stage bilateral simultaneous hip or knee replacement versus two stage.
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  • 文章类型: Journal Article
    为了汇编有关双侧肩关节前脱位(BASD)的现有文献并分析患者的人口统计学,损伤机制,损伤特征,管理,和结果。
    本系统评价按照系统评价和荟萃分析(PRISMA)指南的首选报告项目进行。在线数据库,包括OvidMedline1946-,Embase.com1947-,Scopus1960-,CochraneCentral,和Clinicaltrials.gov被系统地查询。符合纳入条件的研究是病例报告或病例系列,记录BASD。两名评审员独立筛选并将一组先验排除标准应用于每个返回的研究。数据被提取,编译,并从每例报告的BASD病例中合成。应急表/卡方分析,T-tests,进行单变量回归分析以评估不同变量之间的关系。
    纳入81项研究(87例BASD)。患者年龄为41.1(SD±19.5)岁,大多数为男性(n=63;72.4%)。大约四分之一的患者(28.7%)有癫痫/癫痫发作史或正在接受治疗。年轻男性更容易因癫痫发作或触电而患BASD(P<0.05)。近三分之一的病例(n=27;31.0%)延迟出现。那些持续发作或触电的患者更有可能延迟出现(P=0.013)。大多数事件导致简单的位错,这些位错被成功闭合。癫痫发作或电击导致的BASD更可能是骨折脱位(P=0.018);在年轻的骨折脱位患者中,闭合复位失败或不尝试的频率更高(P<0.05)。中位随访时间为6个月(IQR:3个月-12个月)。7例患者(10.6%)出现并发症,4例(2.3%)出现复发性不稳定。
    在没有已知创伤的情况下出现BASD的年轻男性中,对惊厥事件的怀疑应该很高。在已知的癫痫患者中,出现慢性双侧肩或手臂疼痛,应考虑BASD,并应加快检查以避免误诊。
    UNASSIGNED: To compile the existing literature on bilateral anterior shoulder dislocation (BASD) and analyze patient demographics, mechanisms of injury, injury characteristics, management, and outcome.
    UNASSIGNED: This systematic review was conducted in accordance with Preferred Reporting Items for Systematic review and Meta-Analyses (PRISMA) guidelines. Online databases, including Ovid Medline 1946-, Embase.com 1947-, Scopus 1960-, Cochrane Central, and Clinicaltrials.gov were systematically queried. Studies eligible for inclusion were case reports or case-series, documenting BASD. Two reviewers independently screened and applied a set of a priori exclusion criteria to each returned study. Data were extracted, compiled, and synthesized from each reported case of BASD. Contingency tables/Chi-Square Analyses, T-tests, and univariate regression analyses were conducted to assess relationships between different variables.
    UNASSIGNED: Eighty-one studies (87 cases of BASD) were included. Patients were 41.1 (SD± 19.5) years old and most were male (n=63; 72.4%). Around a quarter of patients (28.7%) had a history of epilepsy/seizures or were being worked-up for such. Younger males were more likely to have BASD due to a seizure or electrocution (P<0.05). Close to a third of cases (n=27; 31.0%) were delayed in presentation. Those sustaining seizures or electrocutions were more likely to be delayed in presentation (P=0.013). Most events resulted in simple dislocations that were closed reduced successfully. BASD resulting from seizures or electrocutions were more likely to be fracture-dislocations (P=0.018); and in younger patients with fracture-dislocations, closed reduction was more often to fail or not be attempted (P<0.05). Median follow-up was 6 months (IQR: 3 months - 12 months). Seven patients (10.6%) had complications and 4 (2.3%) demonstrated recurrent instability.
    UNASSIGNED: In young males presenting with BASD without known trauma, suspicion should be high for a convulsant event. In patients with a known seizure disorder who present with chronic bilateral shoulder or arm pain, BASD should be considered and work-up should be expedited to avoid misdiagnosis.
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  • 文章类型: Case Reports
    骨盆指是一种罕见的先天性异常,通常是偶然发现的。我们介绍了一名44岁的男性患者,在道路交通事故后的一次初步调查中,在骨盆X光片上发现了双侧骨盆指。使用计算机断层扫描成像的补充成像证实了罕见的双侧发现。由于患者无症状,因此在切除时没有进行手术尝试。
    A pelvic digit is a rare congenital anomaly and is often discovered incidentally. We present a 44-year-old male patient with bilateral pelvic digits discovered on a pelvic radiograph during a primary survey after a road traffic accident. Supplementary imaging using computed tomographic imaging confirmed the bilateral finding which is rare. No surgical attempt was made at removal as the patient remained asymptomatic.
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  • 文章类型: Journal Article
    目的:评估可能影响双侧输尿管结石患者合理治疗决策过程的某些因素。
    方法:对来自6个中心的153例双侧输尿管结石患者进行评估,并分为三组。第1组(n:21)接受DJ支架插入输尿管和输尿管肾镜(URS)碎石术治疗对侧输尿管结石的患者。第2组(n:91),输尿管结石和接受双侧DJ支架插入的第3组(n:41)患者的URS碎石术。在三组中对手术的结果和相关患者以及结石相关因素进行了比较评估。
    结果:虽然双侧DJ组的尿路感染率和血清肌酐水平明显较高,发现在进行双侧URS的病例中,先前的URS病史明显高于进行双侧DJ支架置入的病例。在输尿管下段结石的情况下,URS的执行频率明显更高,而DJ支架置入术似乎是输尿管上段结石的更合理方法。在输尿管下段结石患者中,更大更硬的石头,内分泌学家倾向于将URS作为第一选择。
    结论:在双侧输尿管结石的情况下做出合理的治疗方法是具有挑战性的。我们的研究结果表明血清肌酐水平,相关UTI,结石的位置和硬度以及先前的输尿管镜检查记录可能是在紧急情况下决定JJ支架置入和输尿管镜下取石的重要因素。
    OBJECTIVE: To evaluate certain factors that may affect the decision-making process for the rational management approach in cases presenting with bilateral ureteral stones.
    METHODS: A total of 153 patients presenting with bilateral ureteral stones from 6 centers were evaluated and divided in three groups. Group 1 (n:21) Patients undergoing DJ stent insertion in one ureter and ureterorenoscopic (URS) lithotripsy for the contralateral ureteral stone. Group 2 (n:91), URS lithotripsy for both ureteral stones and Group 3 (n:41) patients undergoing bilateral DJ stent insertion. The outcomes of the procedures and the relevant patient as well as stone related factors have been comparatively evaluated in three groups.
    RESULTS: While associated UTI rates and serum creatinine levels were significantly higher in bilateral DJ group, previous URS history was found to be significantly higher in cases undergoing bilateral URS than those undergoing bilateral DJ stenting. URS was performed significantly more often in cases with lower ureteral stones and DJ stenting seems to be more rational approach in upper ureteral stones. In patients with lower ureteral stones, larger and harder stones, endourologists tended to perform URS as the first option.
    CONCLUSIONS: Decision making for a rational approach in cases with bilateral ureteral stones my be challenging. Our findings demonstated that serum creatinine levels, associated UTI, location and the hardness of the stone and previous ureteroscopy anamnesis could be important factors in making a decision between JJ stenting and ureteroscopic stone extraction in emergency conditions.
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  • 文章类型: Journal Article
    成骨不全症(OI)是一种以骨骼脆性为特征的异质性疾病。在这里,我们报告了一例双侧股骨头软骨下功能不全骨折(SIF)后诊断为OI的病例。一名37岁的妇女因左髋部疼痛而被转诊到Sa玉医科大学医院,该疼痛持续了2个月,没有任何创伤。她随后被诊断为左股骨头SIF。三个月后,她在没有任何创伤的情况下进一步发展了右髋关节的SIF。在T2加权冠状和矢状图像上,双侧髋关节的磁共振成像显示软骨下骨和股骨头骨髓水肿的线性低信号变化,诊断这两个SIF。骨密度为0.851g/cm2(T评分,-1.3)在腰椎处,0.578g/cm2(T分数,-1.9)在右股骨颈处,和0.582g/cm2(T分数,-1.9)在左股骨颈处。考虑到患者有多处骨折史,蓝色巩膜,轻度双侧感音神经性听力损失,她满足OI的诊断标准。基因检测揭示了COL1A1(NM_000088.3,c.3806G>A:p.Trp1269*)中的突变。经过7个月的保守治疗,她的症状有所改善。四年后,两髋无疼痛,无骨关节炎进展的证据.OI可导致青春期和成年期或以后由于骨脆性引起的骨折不全,没有OI的案例,除了目前的情况,被诊断为双侧SIF的结果。
    Osteogenesis imperfecta (OI) is a heterogeneous disorder characterised by bone fragility. Herein, we report a case of OI diagnosed after subchondral insufficiency fracture (SIF) of bilateral femoral heads. A 37-year-old woman was referred to Saitama Medical University Hospital due to left hip pain without any trauma that lasted for 2 months. She was subsequently diagnosed with SIF of the left femoral head. After 3 months, she further developed SIF of the right hip without any trauma. Magnetic resonance imaging of the bilateral hips showed linear low-signal changes of the subchondral bone and bone marrow oedema of the femoral head on T2-weighted coronal and sagittal images, diagnosing of both SIFs. The bone mineral density was 0.851 g/cm2 (T-score, -1.3) at the lumbar spine, 0.578 g/cm2 (T-score, -1.9) at the right femoral neck, and 0.582 g/cm2 (T-score, -1.9) at the left femoral neck. Considering that the patient had multiple histories of fracture, blue sclera, and mild bilateral sensorineural hearing loss, she satisfied the diagnostic criteria for OI. Genetic testing revealed a mutation in COL1A1 (NM_000088.3, c.3806G>A: p. Trp1269*). After 7 months of conservative therapy, her symptoms improved. After 4 years, both hips were pain-free with no evidence of osteoarthritis progression. OI can result in insufficiency fractures due to bone fragility in adolescence and adulthood or later, and none of the cases of OI, except for the current case, were diagnosed as a result of bilateral SIF.
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  • 文章类型: Case Reports
    包虫病,归因于细粒棘球蚴,在流行地区构成了重大的健康威胁。这里,我们介绍了一例涉及一名来自巴基斯坦农村的15岁男孩的病例,该男孩最初因持续性咳嗽和咯血而就医.尽管最初血清学标志物检测呈阴性,影像学检查显示双肺有明确的囊肿.通过组织病理学检查确认诊断。治疗包括阿苯达唑治疗和囊肿的手术切除。我们的病例强调了与血清阴性病例相关的诊断挑战,并强调了在流行地区考虑包虫病的重要性。与典型的血清学标记无关。本报告增强了对临床表现的理解,诊断方法,肺包虫囊肿的治疗策略。
    Hydatid disease, attributed to the tapeworm Echinococcus granulosus, poses a significant health threat in regions where it is endemic. Here, we present a case involving a 15-year-old boy from rural Pakistan who initially sought medical attention due to a persistent cough and hemoptysis. Despite initially testing negative for serological markers, imaging studies revealed well-defined cysts in both lungs. Confirmation of the diagnosis was achieved through histopathological examination. Management includes albendazole therapy and surgical excision of the cyst. Our case underscores the diagnostic challenges associated with seronegative cases and underscores the importance of considering hydatid disease in endemic regions, irrespective of typical serological markers. This report enhances understanding regarding the clinical presentation, diagnostic approach, and management strategies for pulmonary hydatid cysts.
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