■传统的视听性刺激(AVSS)测试可能会遇到局限性,包括勃起反应率低和缺乏统一的诊断标准。
■我们旨在探讨虚拟现实AVSS(VR-AVSS)测试在评估勃起功能和诊断勃起功能障碍(ED)中的临床价值。
■从2020年6月至2022年3月,在3个临床中心对18至60岁的参与者进行了筛查分析。人口统计数据,5项国际勃起功能指数(IIEF-5),勃起硬度评分(EHS),并收集自我报告的症状问题。根据IIEF-5和EHS确认ED患者和对照患者。在RigiScan录制期间,所有受试者都通过VR设备观看了60分钟的色情视频。参数包括尖端平均刚度,尖端有效勃起持续时间(刚度持续时间≥60%,尖端有效勃起持续时间),基础平均刚度,并对基础有效勃起持续时间进行了评估。
■感兴趣的主要结果是应用VR沉浸技术来改进传统的AVSS测试。
■共纳入301例ED病例和100例合格对照患者进行最终分析。与对照组患者相比,ED病例的IIEF-5评分明显较低,EHS,积极响应率,和勃起刚度和持续时间。ED和对照组患者的阳性率分别为75.5%和90.9%,分别。尖端平均刚度的截止点,提示有效勃起持续时间,基础平均刚度,基础有效勃起持续时间为40.5%(敏感度:77.6%,特异性:70.2%;P<.001),4.75分钟(灵敏度:75.9%,特异性:75.4%;P<.001),48.5%(灵敏度:77.6%,特异性:75.1%;P<.001),和7.75分钟(灵敏度:79.3%,特异性:75.7%;P<.001)。
■VR的技术优势将使VR-AVSS沉浸测试成为比传统AVSS模式更准确的检测。
■我们的研究应用VR沉浸技术来建立AVSS测试的标准操作程序,能有效减少不利因素的干扰,最大限度地减少检测误差。然而,测试数据仅包括阳性反应受试者,因此,无法获得对AVSS测试呈阴性反应的男性的真实勃起状态。
■VR-AVSS测试可有效提高ED的诊断准确性。平均刚度和有效勃起持续时间是排除ED的最佳诊断参数。
UNASSIGNED: The traditional audiovisual sexual stimulation (AVSS) test may experience limitations including low erectile response rate and lack of unified diagnostic criteria.
UNASSIGNED: We aimed to explore the clinical value of AVSS with virtual reality (VR-AVSS) test in assessing erectile function and diagnosing erectile dysfunction (ED).
UNASSIGNED: Participants 18 to 60 years of age were screened for analysis in 3 clinical centers from June 2020 to March 2022. Demographic data, 5-item International Index of Erectile Function (IIEF-5), erectile hardness score (EHS), and self-reported symptom questions were collected. The ED patients and control patients were confirmed according to the IIEF-5 and EHS. All subjects watched a 60-minute erotic video by VR device during RigiScan recording. The parameters including tip average rigidity, tip effective erectile duration (duration of rigidity ≥60%, tip effective erectile duration), base average rigidity, and base effective erectile duration were evaluated.
UNASSIGNED: The main outcome of interest was the application of VR immersion technology to improve the traditional AVSS test.
UNASSIGNED: A total of 301 ED cases and 100 eligible control patients were included for final analysis. Compared with control patients, ED cases had significantly lower IIEF-5 scores, EHS, positive response rate, and erectile rigidity and duration. The positive response rate of ED and control patients were 75.5% and 90.9%, respectively. The cutoff points of tip average rigidity, tip effective erectile duration, base average rigidity, and base effective erectile duration were 40.5% (sensitivity: 77.6%, specificity: 70.2%; P < .001), 4.75 minutes (sensitivity: 75.9%, specificity: 75.4%; P < .001), 48.5% (sensitivity: 77.6%, specificity: 75.1%; P < .001), and 7.75 minutes (sensitivity: 79.3%, specificity: 75.7%; P < .001).
UNASSIGNED: The technological superiority of VR will enable the VR-AVSS immersion test to be a more accurate detection than traditional AVSS modes.
UNASSIGNED: Our study applied VR immersion technology to establish the standard operation procedure for the AVSS test, which could effectively reduce the interference of adverse factors and minimize the detecting errors. However, the test data only included positive response subjects, so the true erectile status of men with a negative response to the AVSS test cannot be obtained.
UNASSIGNED: The VR-AVSS test can effectively improve the diagnostic accuracy of ED. The average rigidity and effective erectile duration were the optimal diagnostic parameters for excluding ED.