现代自动化实验室血液学分析仪使用各种方法来测量不同的血液学参数。这些参数在患者症状的诊断和临床解释中是有用的。所以,这是非常重要的比较不同的分析仪测量相同的参数。因此，对SysmexXN3000和HoribaYumizenH2500分析的全血细胞计数进行了比较。在收集的4小时内，在两个分析仪中处理了总共296份EDTA抗凝血样品。白细胞计数,红细胞计数,红细胞指数,白细胞分类计数，比较血小板计数、血小板指数和网织红细胞计数。在不同参数之间获得了良好的相关性和一致性。对于WBC（0.997），SysmexXN3000和YumizenH2500之间观察到了很强的相关性（r>0.9），红细胞（0.997），血红蛋白（0.999），血细胞比容（0.974），MCV(0.902),MCH(0.99)，,阻抗血小板计数（0.989），平均血小板体积（0.954），plateletcrit(0.971),血小板分布宽度（PDW）（0.916），中性粒细胞（0.997），淋巴细胞（0.989），单核细胞（0.943），和嗜酸性粒细胞（0.991）计数。对于RDW-CV(0.75)观察到中等相关性。嗜碱性粒细胞计数显示较差的相关性(r<0.5),这可能是由于样本选择的嗜碱性粒细胞计数大多较低。对于大多数参数，如WBC，观察到可接受的偏差，红细胞,血红蛋白,血细胞比容,血小板计数,中性粒细胞，淋巴细胞，嗜酸性粒细胞和单核细胞。所研究的仪器除了很少的参数外，还确保了令人满意的互换性。因此，在不影响临床决策的情况下，促进一个分析仪被另一个分析仪的替代。
Modern automated laboratory haematology analysers use various methods to measure different haematological parameters. These parameters are useful in the diagnostic and clinical interpretation of patient symptoms. So, it is very important to compare the performance of different analysers measuring the same parameter. Hence, a comparison of complete blood counts analysed by Sysmex XN 3000 and Horiba Yumizen H2500 was performed. Total 296 EDTA anti-coagulated blood samples were processed in both the analysers in duplicate within 4 h of collection. The white blood cell count, red blood cell count, erythrocyte indices, differential leukocyte count, platelet count and platelet indices and reticulocyte count were compared. A good level of correlation and agreement between different parameters were obtained. A strong correlation was observed (r > 0.9) between Sysmex XN 3000 and Yumizen H2500 for WBC (0.997), RBC (0.997), Haemoglobin (0.999), haematocrit (0.974), MCV (0.902), MCH (0.99),, platelet count by impedance (0.989), mean platelet volume (0.954), plateletcrit (0.971), platelet distribution width (PDW) (0.916), neutrophils (0.997), lymphocytes (0.989), monocytes (0.943), and eosinophils (0.991) counts. A moderate correlation was observed for RDW-CV (0.75). The basophils count showed poor correlation (r < 0.5) possibly because of sample selection with mostly low basophils count. An acceptable bias was observed for most of the parameters like WBC, RBC, Haemoglobin, Haematocrit, platelet counts, neutrophils, lymphocytes, eosinophils and monocytes. The studied instruments ensured satisfactory interchangeability except for few parameters, thus facilitate substitution of one analyser by another without affecting the clinical decision making.
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