未经证实:腹内粘连(IAAs)继发于腹膜损伤,例如先前的手术或腹内感染(IAIs)。因此,在任何手术中,采用拟合技术以最大限度地减少粘连的可能性是至关重要的。由于缺乏类似的数据,本研究旨在探讨诱导的高血清腹水白蛋白梯度(SAAG)和低血清腹水白蛋白梯度(SAAG)对小鼠模型术后微观和宏观粘附率的影响。
UNASSIGNED:将60只小鼠分为6组,每组10只。对照组(1和4)接受生理盐水,第2组和第5组接受高SAAG腹水,第3组和第6组腹膜内接受低SAAG腹水。这些小组在第0天接受了剖腹探查术,随后在手术的第10天(第1、2、3组)和第30天(第4、5、6组)进行相同的程序。然后,对微观和宏观IAA进行了评估。采用SPSS软件对数据进行分析,p值小于0.05。
UNASSIGNED:相比之下,在低SAAG腹水组中,在10天和30天后发现的微观和宏观IAA最少。与其他两组相比,差异有统计学意义(P=0.01)。手术10天后,与对照组和低SAAG腹水组相比,高SAAG组的宏观IAA明显降低。
UNASSIGNED:腹内低SAAG腹水可以显着降低术后纤维化和粘连带形成的概率。
未经评估:IR。BUMS.REC.1399.503.
UNASSIGNED: Intra-abdominal adhesions (IAAs) are secondary to peritoneal injuries such as previous surgery or intra-abdominal infections (IAIs). Accordingly, it is crucial to employ fitting techniques to minimize the likelihood of adhesions in any surgery. Due to a paucity of similar data available, this study sought to explore the effects of induced high serum ascites albumin gradient (SAAG) and low serum ascites albumin gradient (SAAG) on the rate of post-operative microscopic and macroscopic adhesion in a mouse model.
UNASSIGNED: Sixty mice were compared in six groups of ten each. Control groups (1 &4) received normal saline, groups 2&5 received high SAAG ascites fluid, and groups 3&6 received low SAAG ascites fluid intraperitoneally. These groups underwent exploratory laparotomy on day zero, followed by the same procedure on the 10th (groups 1,2,3) and the 30th (Groups 4,5,6) day of surgery. Then, microscopic and macroscopic IAAs were evaluated. Data were analyzed in SPSS software and compared with a p-value less than 0.05.
UNASSIGNED: By comparison, the least microscopic and macroscopic IAAs after 10 and 30 days were found in the low SAAG ascites group. Revealing a statistically significant difference compared to the other two groups (P = 0.01). After 10 days of surgery, macroscopic IAA in the high SAAG group was significantly lower compared to the control and Low SAAG ascites groups.
UNASSIGNED: Intraabdominal low SAAG ascites fluid can significantly decrease the probability of postoperative fibrosis and adhesion band formation.
UNASSIGNED: IR. BUMS.REC.1399.503.