Successful artificial intelligence (AI) implementation is predicated on the trust of clinicians and patients, and is achieved through a culture of responsible use, focusing on regulations, standards, and education. Otolaryngologists can overcome barriers in AI implementation by promoting data standardization through professional societies, engaging in institutional efforts to integrate AI, and developing otolaryngology-specific AI education for both trainees and practitioners.

The development of artificial intelligence (AI) has revolutionised the medical system, empowering healthcare professionals to analyse complex nonlinear big data and identify hidden patterns, facilitating well-informed decisions. Over the last decade, there has been a notable trend of research in AI, machine learning (ML), and their associated algorithms in health and medical systems. These approaches have transformed the healthcare system, enhancing efficiency, accuracy, personalised treatment, and decision-making. Recognising the importance and growing trend of research in the topic area, this paper presents a bibliometric analysis of AI in health and medical systems. The paper utilises the Web of Science (WoS) Core Collection database, considering documents published in the topic area for the last four decades. A total of 64,063 papers were identified from 1983 to 2022. The paper evaluates the bibliometric data from various perspectives, such as annual papers published, annual citations, highly cited papers, and most productive institutions, and countries. The paper visualises the relationship among various scientific actors by presenting bibliographic coupling and co-occurrences of the author\'s keywords. The analysis indicates that the field began its significant growth in the late 1970s and early 1980s, with significant growth since 2019. The most influential institutions are in the USA and China. The study also reveals that the scientific community\'s top keywords include \'ML\', \'Deep Learning\', and \'Artificial Intelligence\'.

Cognitive impairments are a prevalent consequence of acquired brain injury, dementia, and age-related cognitive decline, hampering individuals\' daily functioning and independence, with significant societal and economic implications. While neurorehabilitation represents a promising avenue for addressing these deficits, traditional rehabilitation approaches face notable limitations. First, they lack adaptability, offering one-size-fits-all solutions that may not effectively meet each patient\'s unique needs. Furthermore, the resource-intensive nature of these interventions, often confined to clinical settings, poses barriers to widespread, cost-effective, and sustained implementation, resulting in suboptimal outcomes in terms of intervention adaptability, intensity, and duration. In response to these challenges, this paper introduces NeuroAIreh@b, an innovative cognitive profiling and training methodology that uses an AI-driven framework to optimize neurorehabilitation prescription. NeuroAIreh@b effectively bridges the gap between neuropsychological assessment and computational modeling, thereby affording highly personalized and adaptive neurorehabilitation sessions. This approach also leverages virtual reality-based simulations of daily living activities to enhance ecological validity and efficacy. The feasibility of NeuroAIreh@b has already been demonstrated through a clinical study with stroke patients employing a tablet-based intervention. The NeuroAIreh@b methodology holds the potential for efficacy studies in large randomized controlled trials in the future.

The black-box nature of machine learning models hinders the deployment of some high-accuracy medical diagnosis algorithms. It is risky to put one\'s life in the hands of models that medical researchers do not fully understand or trust. However, through model interpretation, black-box models can promptly reveal significant biomarkers that medical practitioners may have overlooked due to the surge of infected patients in the COVID-19 pandemic. This research leverages a database of 92 patients with confirmed SARS-CoV-2 laboratory tests between 18th January 2020 and 5th March 2020, in Zhuhai, China, to identify biomarkers indicative of infection severity prediction. Through the interpretation of four machine learning models, decision tree, random forests, gradient boosted trees, and neural networks using permutation feature importance, partial dependence plot, individual conditional expectation, accumulated local effects, local interpretable model-agnostic explanations, and Shapley additive explanation, we identify an increase in N-terminal pro-brain natriuretic peptide, C-reaction protein, and lactic dehydrogenase, a decrease in lymphocyte is associated with severe infection and an increased risk of death, which is consistent with recent medical research on COVID-19 and other research using dedicated models. We further validate our methods on a large open dataset with 5644 confirmed patients from the Hospital Israelita Albert Einstein, at São Paulo, Brazil from Kaggle, and unveil leukocytes, eosinophils, and platelets as three indicative biomarkers for COVID-19.

UNASSIGNED: The objective of the study is to evaluate the performance of CNN-based proposed models for predicting patients\' response to NAC treatment and the disease development process in the pathological area. The study aims to determine the main criteria that affect the model\'s success during training, such as the number of convolutional layers, dataset quality and depended variable.
UNASSIGNED: The study uses pathological data frequently used in the healthcare industry to evaluate the proposed CNN-based models. The researchers analyze the classification performances of the models and evaluate their success during training.
UNASSIGNED: The study shows that using deep learning methods, particularly CNN models, can offer strong feature representation and lead to accurate predictions of patients\' response to NAC treatment and the disease development process in the pathological area. A model that predicts \'miller coefficient\', \'tumor lymph node value\', \'complete response in both tumor and axilla\' values with high accuracy, which is considered to be effective in achieving complete response to treatment, has been created. Estimation performance metrics have been obtained as 87%, 77% and 91%, respectively.
UNASSIGNED: The study concludes that interpreting pathological test results with deep learning methods is an effective way of determining the correct diagnosis and treatment method, as well as the prognosis follow-up of the patient. It provides clinicians with a solution to a large extent, particularly in the case of large, heterogeneous datasets that can be challenging to manage with traditional methods. The study suggests that using machine learning and deep learning methods can significantly improve the performance of interpreting and managing healthcare data.